• Korean Journal of Food Science and Technology
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• v.43 no.4
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• pp.513-517
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• 2011

The effects of nonthermal plasma treatments against Salmonella Typhimurium, Escherichia coli O157:H7, and Listeria monocytogenes living on polystyrene (PS), sausage casings, and smoked salmon were investigated. Inoculated PS, casings, and salmon were treated with nonthermal plasma generated with helium (5 L/min) or with both helium (5 L/min) and oxygen (100 mL/min) at 60 Hz and 30 kV/cm for 2, 5, or 10 min. S. Typhimurium exhibited the highest sensitivity to the helium-used treatment. The greatest reduction (3.9${\pm}$0.8 log$CFU/cm^2$) was observed with L. monocytogenes on PS after the treatment with the mixed gas for 5 min. The treatment with the mixed gas inhibited L. monocytogenes on casings and salmon by 0.5${\pm}$0.3 log$CFU/cm^2$ and 1.0${\pm}$0.3 log CFU/g, respectively. Different treatment times did not result in different reductions of L. monocytogenes on both casings and salmon. The types of treatment gas and material of contamination need to be considered for evaluating the antimicrobial effects of nonthermal plasma treatments.

• Physical Therapy Korea
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• v.11 no.2
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• pp.47-63
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• 2004

In most tissues, apoptosis plays a pivotal role in normal development and in regulation of cell number. Therefore inappropriate apoptosis is revealed in a variety of diseases. This study was carried out to investigate the effects of acupuncture and needle electrode electrical stimulation on the change of caspase-3, 9 and neuronal nitric oxide synthase (nNOS) immunoreactive cells in the sprague dawley rats (SD rat). In immobilized SD rats (n=5), enhanced caspase-3 and caspase-9 expression were detected in the reticular part of substantia nigra, and enhanced nNOS was detected in the dorsolateral periaqueductal gray (DL-PAG) of midbrain and the paraventricular nucleus (PVN) of the hypothalamus using immunohistochemistry. Following the immobilization, acupuncture (n=5) and needle electrode electrical stimulation (n=5, 2 Hz) was applied at H$\acute{e}$g$\breve{u}$ (LI4) acupoint of SD rats, respectively. The stress-induced enhancement in the expression of caspase-3, 9 and nNOS were The present results demonstrate that and needle electrode electrical stimulation are effective in the modulation of expression of caspase-3, 9 and nNOS induced by immobilization.

• Proceedings of the Materials Research Society of Korea Conference
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• 1994.11a
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• pp.98-98
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• 1994

최근 청색반도체레이저의 실현을 위하여 ZnSe가 대표하는 II-Ⅵ족 화합물반도체와 Gan가 대표하는 III족 질화물반도체분야에서 집중적인 연구가 이루어지고 있으며, 아직까지 실용화 되지 않고 있는 청색반도체레이저의 출현에 대하여 많은관심이 모아지고 있다. III족 질화물반도체는 InM(Eg:1.9eV)부터 AIN(Eg: 6.2eV)에 이르기까지 전 조성영역에서 완전한 고용체를 이루며, 실온에서 직접천이형 에너지 대구조를 가지므로 청색 혹은 자외영역에서 동작하는 발광소자를 제작하는데 있어 유망시 되고 있는 소재이다. 특히 GaN와 InN의 3원흔정인 GaInN를 활성층으로 이용하면 그 발전파장을 370nm부터 650nm까지 즉 가시 전 영역으로부터 근 자외영역을 포함할 수 있게 된다. 이 연구에서는 AIGaN/GaInN 이중이종접합(DH) 구조의 고아여기에 의한 유도방출고아의 편광 특성을 조사하였다. 유기금속기상에피텍셜(MOVPE)법으로 성장한 AIGaN/GaInN DH 구조의 표면에 수직으로 펄스 발진 질소레이저(파장: 337.1cm, 주기 10Hz, 폭: 8nsec) 빔을 조사하고 DH구조의 단면으로부터의 유도방출광을 편광기를 통과 시킨 후 스펙트럼을 측정하였다. 입사고아 밀도가 증가함에 따라 약 402nm의 파장에서 유도발출에 의한 가도가 큰 피크가 나타났고, 그 반치폭은 약 18meV이었다. 실온에서 AIGaN/GaInN DH 구조로 부터의 유도방출에 필요한 입사광밀도의 임계치는 약 130㎾/$\textrm{cm}^2$이었다. 한편 편광각이 90$^{\circ}$일때는 발광스펙트럼의 강도가 매우 낮고 단지 자연방출에 의한 스펙트럼만이 나타났다. 편광각이 0$^{\circ}$일 때 최대의 방출광 강도를 나타내었으며, 편광각이 -90$^{\circ}$로 회전함에 따라 발고아강도의 강도가 감소하였다. 이와 같은 결과는 광여기에 의하여 AIGaN/GaInN DH 로 부터의 유도방출광이 GaInN활성층의 단면에 평행한 전기장의방향으로, 즉 TE모드로 선형적으로 편광됨을 의미한다. AIGaN/GanN DH 로 부터의 유도방출이 선형적으로 TE모드로 편광되는 것은 이 구조를 이용한 청색 및 자외선 반도체 레이저다이오드의 실현에 매우 유익한 것이다.

• Journal of the Korean Vacuum Society
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• v.19 no.1
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• pp.36-44
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• 2010

The ambipolar diffusion equation has been solved in a fine-tube lamp of a few mm in diameter. In the diffusion of radial direction, the plasma diffuses and vanishes away at the glass wall by recombination with the characteristic time of plasma loss is given by $\tau_r\;=\;(r_0/2.4)^2/D_a$. With the radius $r_0{\sim}1\;mm$ and the ambipolar diffusion coefficient $D_a{\sim}0.01\;m^2/s$, the vanishing time is calculated $\tau_r{\sim}10\;{\mu}s$ which corresponds to the least value of frequency 30 kHz for the sustaining the plasma in the operation of high voltage AC-power. In the diffusion of longitudinal z-direction, a high density plasma generated at the area of a high voltage electrode, diffuses into the positive column with the characteristic time $\tau_z{\sim}0.1\;s$. The plasma diffusion velocity at the boundary of high density plasma is $u_D{\sim}10^2\;m/s$ at the time $t{\sim}10^{-6}$ s and the diffusion velocity becomes slow as $u_D{\sim}1\;m/s$ at $t{\sim}10^{-3}\;s$. Therefore, for the long lamp of 1 m, it takes about several seconds for the high density plasma at the area of electrode to diffuse through the whole positive column space.

• Proceedings of the Materials Research Society of Korea Conference
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• 1994.11a
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• pp.97-97
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• 1994

Wide gap 반도체 중 하나인 GaN 에너지갭이 실온에서 3.4eV 이고 직접천이형 에너지대 구조를 가지므로 청색 및 자외영역의 파장을 발광하는 발광다이오드와 바도체 레이저 다이오드의 제작에유용한 재료이다. GaN계 III족 질화물반도체가 다파장용 광원으로서 유망함을 보인 것은 1970년대 초방의기초적 연구이다. 이로부터 약 25년이 경고한 현재 청색발광다이오드가 실용화당계에 이르게 되었지만 아직까지 전류주입에 의한 레이저발진은 보고되고있지 않다. 이 논문에서는 ALGaN/GaN이중이종접합(DH) 구조의 광여기에 의한 유도방출과 광학적 이득을 측정하므로서 전류주입에의한 레이저발진의 가능성을 조사하였다. 유기금속기상에피텍셜(MOVPE)법으로 성장한 ALGaN/GaN DH구조의 표면에 수직으로 펄스발진 질소레이저(파장:337.1nm, 주기:10Hz, 폭: 8nsec) 빔의 공출력밀도를 변화시키어 조사하고 시료의단면 혹은 표면으로부터 방출되는 광 스펙트럼을 측정하였다. 입상광밀도가 증가함에 따라 자연방출에 의한 발광피크보다 낮은 에너지에서 발광강도가 큰 유도방출에 의한 피크가 370nm의 파장에서 현저하게 나타났으며 실온에서 유동방출에 필요한 입사공밀도의 임계치는 약 89㎾/$\textrm{cm}^2$이었다. 이는 GaN 단독층에 대한 유동방출의 임계치 700㎾/$\textrm{cm}^2$ 에 비하여 약 1/8정도 낮은 것이며, 이를 전류밀도로 환산하면 약 27㎄/$\textrm{cm}^2$ 정도로서 전류주입에 의하여서도 레이저발진을 실현할 수 있는 현실적인 값이다. 한편 광여기 방법으로 측정한 광학적 이득은 입사광의 밀도가 각각 100㎾/$\textrm{cm}^2$과 200㎾/$\textrm{cm}^2$일 때 34$cm^{-1}$ / 과 160 $cm^{-1}$ / 이었다. 이와 같은 결과는 GaN의밴드단 부근의 파장영역에서 AIGaN 흔정의 굴절율이 GaN의 굴절율보다 작으므로 DH구조의 채택의 의한 광의 몰입이 가능하여 임계치가 저하된 것으로 여겨진다. 또한 광학적 이득의 존재는 이 구조에 의한 극단파장 반도체 레이저다이오드의 실현 가능성을 나타내는 것이다.

• The Journal of Korean Physical Therapy
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• v.19 no.1
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• pp.57-66
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• 2007

Purpose: We investigated the effects of the combined therapy in rats with rheumatoid arthritis induced by type II collagen for 28 days, which consisted of the oral administration of the AR and EA applied to zusanli acupoint(ST36). Methods: Normal group was oral administered with 0.9% NaCl $0.5\;m{\ell}/day$ to normal rats. Control group was oral administered with 0.9% NaCl $0.5\;m{\ell}/day$ to arthritic rats. Group I was oral administered with AR 500 mg/kg $0.5\;m{\ell}/day$ to arthritic rats. Group II was given 2 Hz EA of ST36 in the test group for 30 min/day to arthritic rats. Group III was oral administered with AR 500 mg/kg $0.5\;m{\ell}/day$ and 2 Hz EA of ST36 in the test group for 30 min/day to arthritic rats. We Observed effect of the histopathological changes by H&E stain of liver, kidney, knee joint and ELSIA of cytokines($TNF-{\alpha}$). Results: 1. The vacuolization of liver tissue was decreased in group I, II, III comparing with control group. 2. The glomerular sclerosis of kidney tissue was decreased in group I, II, III comparing with control group. 3. The erosion of arthritic site of knee joint tissue was decreased group I, II, III comparing with control group. In particular group III was the most effective comparing with group I, II on the histopathological view. 4. In the ELSIA test of $TNF-{\alpha}$ concentration, Control group significantly increased in the concentration more than group I, II, III. The rate of increase in concentration slowed down in group III more than group I, II(p<0.05). Conclusion: It is concluded that 500 mg/kg of AR extracts and EA have clear therapeutic effect on the rheumatoid arthritis.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.29 no.2
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• pp.123-131
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• 2007

Introduction: Distraction osteogenesis is widely used as for bone lengthening in patients with maxillofacial deformity and alveolar bone atrophy. One of the major problems in distraction osteogenesis is long consolidation period for 2-3 months, in which the devices have to be fixed on the bone to prevent relapse. It results in scar formation on the face, disturbance of mastication and speech. This study was performed to evaluate the stimulating effect of pulsed electromagnetic field on the early bone consolidation in distraction osteogenesis. Materials and methods: Total 10 rabbit were used (5 for control group, 5 for experimental group). A vertical osteotomy in the mandibular body was performed and the distraction device was fixed. After 5 days distraction was done 1mm per a day for 7 days. A pulsed electromagnetic field (38 Gauss, 60 Hz) was applied for 8 hours per day and it continued for 5 days immediately after distraction in the experimental group. Both groups were sacrificed after 2 weeks. Histological specimens with H&E and Masson Trichrome staining were made and histomorphometrically analysed with image analyser. Results: The device for distraction osteogenesis was displaced in one animal for each group, therefore, only four animals in both groups were evaluated. In both groups, a new bone formation was observed in the distracted area after 2 weeks. The bone formation was enhanced in the experimental groups ($31.76{\pm}8.68%$) compared with control group ($9.94{\pm}3.23%$), its difference was statistically significant (p<0.001). Conclusion: This study suggests that electrical stimulation with electromagnectic field may be effective in the early bone formation after distraction osteogenesis. Further studies with large number of animals are needed before clinical application.