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Stathmin 1 in normal and malignant hematopoiesis

  • Machado-Neto, Joao Agostinho;Saad, Sara Teresinha Olalla;Traina, Fabiola
    • BMB Reports
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    • 제47권12호
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    • pp.660-665
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    • 2014
  • Stathmin 1 is a microtubule destabilizer that plays an important role in cell cycle progression, segregation of chromosomes, clonogenicity, cell motility and survival. Stathmin 1 overexpression has been reported in malignant hematopoietic cells and Stathmin 1 inhibition reduces the highly proliferative potential of leukemia cell lines. However, during the differentiation of primary hematopoietic cells, Stathmin 1 expression decreases in parallel to decreases in the proliferative potential of early hematopoietic progenitors. The scope of the present review is to survey the current knowledge and highlight future perspectives for Stathmin 1 in normal and malignant hematopoiesis, with regard to the expression, function and clinical implications of this protein.

Diarrheagenic pathogens in calves with diarrhea in Chungcheongbuk-do, Korea, from 2018 to 2021

  • Kim, Ah Young;Lee, Seung-Hun
    • 한국동물위생학회지
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    • 제45권3호
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    • pp.201-209
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    • 2022
  • An epidemiological study was conducted to investigate five diarrhea-causing pathogens (coronavirus, rotavirus, E. coli, Cryptosporidium, Giardia) using a rapid diagnostic kit in Hanwoo calves with diarrhea in Chungcheongbuk-do, Korea, from 2018 to 2021. A total of 22,417 fecal samples were collected from calves under 1 year of age; of those, 13,518 (60.3%) were positive for five bovine diarrhea antigens. The antigen positivity rates for rotavirus, coronavirus, E. coli, Giardia, and Cryptosporidium were 34.5%, 11.0%, 8.2%, 4.7%, and 2.0%, respectively. The prevalence of the five pathogens in calves was statistically higher in autumn and winter. The highest prevalence of the pathogens was observed in the under 1 month age group, and the incidence of diarrhea decreased with age. Rotavirus was a major pathogen in calves under 1 month of age, whereas the prevalence of E. coli increased with age. This study provides epidemiological evidence of the prevalence of calf diarrheal pathogens in Chungcheongbuk-do, Korea, which will facilitate early diagnosis and development of measures against calf diarrhea.

First record of the Cheekscaled frill-goby, Bathygobius cotticeps (Gobiiformes: Gobiidae) from Jeju-do Island, Korea

  • Min-Soo Kim;Heung-Heon Lee;Young-Min Ko;Sung-Geun Jo;Jae-Goo Kim
    • Fisheries and Aquatic Sciences
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    • 제27권8호
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    • pp.533-537
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    • 2024
  • A single specimen of Bathygobius cotticeps (41.0 mm SL) was collected from the rocky pools of intertidal zone of Jeju-do Island, Korea. This species is characterized by having VI-I, 9 dorsal fin rays, I, 8 anal fin rays, scales on cheek and opercle, 23 predorsal scales, 38 longitudinal scales, 24 pectoral fins, 7 free rays on upper pectoral fin, each divided to 5-7 branches, cephalic sensory canal pores H and K fused, and the middle of pelvic frenum curved inwards smoothly. We propose a new Korean name, "Bi-neulmu-nui-mang-duk" for the B. cotticeps based on the presence of scales on the cheek.

제주도 무인도서의 식물상과 생활형 (Flora and Life-form of the Uninhabited Islets, in Jeju-do)

  • 송국만;현화자;강창훈;김문홍
    • 한국환경과학회지
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    • 제18권11호
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    • pp.1309-1324
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    • 2009
  • This study was survey a flora and life form spectrum of 11 uninhabited islets, in jeju-do. The vascular plants of each uninhabited islets were summarized as Beomseom 159 taxa, Chagwi-do 136 taxa, Daryeo-do 81 taxa, Hyeongje-do 61 taxa, Jigwi-do 39 taxa, Munseom 147 taxa, Ran-do 58 taxa, Saeseom 65 taxa, Seogeondo 60 taxa, Seopseom 183 taxa and Wa-do 46 taxa. Floristic richness was in order analyzed to be Seogeon-do 28.62, Ran-do 19.24, Daryeo-do 18.53, Wa-do 16.42, Munseom 16.14, Hyeongje-do 14.76, Seopseom 13.32, Beomseom 13.24, Chagwi-do 6.15, Saeseom 5.86 and Jigwi-do 2.51. Life form spectrum was surveyed to H-$D_5$-$R_4$-e; hemieryptophyte(H) 26.8%, not production seeds($D_5$) 54.4%, clonal growth by stolons and struck roots($R_4$) 46.9% and erect form(e) 30.3%. According to the life form spectrum hemieryptophyte dominated high portions, which suggests islet in jeju-do has hemieryptophytic climate and similar to middle parts in Korean Peninsular. However, were noticed by that it has more therophytes. As a result, Partially shows the characteristics change from the temperate climate to the warm temperate climate or a semitropical climate by a climatic change.

The Utilization of e-resources at Modibbo Adama University of Technology (MAUTech), Yola, Adamawa State, Nigeria

  • Joshua, Dauda;King, Lizette
    • International Journal of Knowledge Content Development & Technology
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    • 제10권1호
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    • pp.47-70
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    • 2020
  • This article examines the utilization of e-resources Modibbo Adama University of Technology, (MAUTech) Yola under the auspices of the central library, the Ibrahim Babangida Library. Academics and students are primary users of information resources of any library, hence, their responses towards the utilization of e-resources in the institution have been critically considered in this study. A Mixed method research Design was adopted for the study. A case study approach was employed. The Technology Acceptance Model (TAM) and Diffusion of Innovation (DoI) theories were used to develop the conceptual framework of this paper. Questionnaires were used as data gathering tools. Academics and students acted as participants. Major findings are lack of sufficient Internet access for academics and students and lack of training and awareness campaigns. Conclusion has shown that e-resources did not impact research and teaching of academics in MAUTech, Yola.

브라질 실용 포어에 미친 아프리카어의 어휘적 영향 (A Influência de Vocabulários de Origem Africana em Uso no Português Brasileiro)

  • 김한철
    • 이베로아메리카
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    • 제13권1호
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    • pp.1-39
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    • 2011
  • O presente estudo tem como objetivo principal analisar a influência de vocabulários de origem africana em uso no português brasileiro(PB). A fim disso, observamos os tipos e as características das línguas africanas. E ainda, para compreender a situação atual de uso desses termos no Brasil, apresentamos um panorama do registro dos vocábulos de origem africana no PB, e organizamos os vocabulários em três categorias, especialmente, nos registros dos séculos XIX e XX. Em primeiro, a categoria 1 pode ser usada em qualquer interação social, contrastando com as outras duas categorias. Em segundo, a categoria 2 é constuída de termos informais, de uso coloquial que, eventualmente, dependendo da situação, são substituídos por outras. Por último, a categoria 3 é de termos marcadamente informais, de uso restrito. Através disso, comparamos os registros anteriores com os dados obtidos da nossa pesquisa. Com os resultados, podemos reconhecer a estabilidade e o dinamismo do uso desses termos hoje no PB.

낙동강 하구역 진우도 해빈의 춘추계 표층퇴적물 조직변수의 변화 (Variation of the textural parameters of surface sediments between spring and fall season on the Jinu-do beach, Nakdong River estuary)

  • 김부근;김백운;이상룡
    • 한국해안·해양공학회논문집
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    • 제21권6호
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    • pp.444-452
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    • 2009
  • 진우도 해빈에서 2005년 11월과 2006년 5월의 2회에 걸쳐서 표층퇴적물을 채취하여 퇴적물의 조직변수를 분석하였다. 2005년 11월에 비하여 2006년 5월에는 진우도 서쪽 해빈의 최빈값은 $3.0\phi$(i.e., 0.125 mm)로 변화가 거의 없었으나, 동쪽 해빈에서는 최빈값$3.0\phi$(i.e., 0.125 mm)의 함량이 대폭 감소하고 $2.5\phi$(i.e., 0.177 mm)가 절대적으로 우세한 조립화 경향이 발생하였다. 마찬가지로 표층퇴적물 평균 입도는 서쪽 해빈에서는 두 조사의 차이가 거의 미약하지만, 동쪽 해빈의 평균입도는 증가되어 조립화된 특징을 반영한다. 이러한 조립화는 2006년 5월에 진우도의 동쪽 해빈의 표층퇴적물에서 상대적으로 양의 값으로 변화된 왜도 경향과 일치한다. 결과적으로 2005년 겨울을 지나면서 진우도의 표층퇴적물은 서쪽 해빈은 큰 변화를 보이지 않는 반면에 동쪽 해빈은 $3.0\phi$(i.e., 0.125 mm)의 세립 사질퇴적물이 제거되는 현저한 조립화 경향이 나타난 것이다. 이와 같은 변화는 낙동강 하구역에 하계동안 증가된 강수량과 낙동강 방출량 그리고 동계동안 우세한 파랑 그리고 조석의 영향 등이 복합적으로 작용하여 진우도 서쪽 해빈과 동쪽 해빈의 표층퇴적물에 영향을 주는 수리학적 조건과 퇴적물의 공급/제거가 다르기 때문이다.

도정율에 따른 미강의 Tocotrienol과 Tocopherol 함량 (Tocotrienol and Tocopherol Contents of Rice Bran by Milling Recovery)

  • 박경열;강창성;조영철;이용선;이영현;이영상
    • 한국작물학회지
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    • 제49권6호
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    • pp.468-471
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    • 2004
  • 추청벼 등 4품종의 현미를 4.0, 6.4, 8.0, 9.6, $12.0\%$로 도정하여 벼의 도정율과 미강 중의 tocooienol 및 tocopherol 그리고 vitamin I 함량과의 관계를 구명하고자 본 시험을 수행한 결과는 다음과 같다. 1. 미강의 tocotrienol 함량이 최대가 되는 도정율은 4품종 각각 다른 반응을 보였으나 공통으로 가장 높았던 도정율은 6.4\%$이었고 추청벼와 안다벼는 도정율 $8.0\%$에서도 유의차가 없었다. 2. 미강의 tocopherol 함량은 4품종 모두 도정율 $8.0\%$에서 가장 높게 나타났으며, 일품벼 고시히카리 안다벼 3품종은 $9.6\%$에서도 유의차가 없었다. 3. 미강의 vitamin E함량이 가장 높은 도정율은 $8.0\%$이나 실험 품종들 간에 다소 차이는 있으나 대체로 $6.4-9.6\%$의 도정율에서는 유의차가 없었다. 4. 쌀의 tocotrienol, tocopherol 그리고 vitamin E함량은 도정율이 높아질수록 감소되는 경향으로 도정율 $8\%$일때 각각의 함량은 11.0, 8.2, $19.2 mg{\cdot}kg^{-1}$이었고, 쌀에는 tocotrienol과 tocopherol 동족체 중 $\alpha-$$\gamma-$가 검출되었다.

소하천 유역에서의 오염 유입량 예측 (Forecasting of Pollution Inflow of the Small Channel Catchment)

  • 김동필;전민우;임동희
    • 한국환경과학회지
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    • 제17권4호
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    • pp.451-459
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    • 2008
  • This study was carried out forecasting of pollution inflow of the Small Mountainous Catchment, namely; Seolma-cheon experimental catchment. Pollutographs of DO, BOD, T-N, Conductivity, T-p, pH. COD, SS from this catchment were obtained from in-situ data of total ten events using QUAL2E-PULS model. From the analysis results, between up stream(Sabang-bridge) and down stream (Memorial-bridge, outlet) obtained relation formula of water quality component. Determination coefficient of relation formula, Conductivity, COD, BOD, DO, pH, T-N, T-P, and SS showed high relation of $0.87{\sim}0.99$. The increases of DO, BOD, COD, and pH concentration of Memorial-bridge were associated with pollution inflow by road building far 2.25km from Sabang-bridge to down stream. The analysis results of QUAL2E-PULS simulation and up/down stream relation formula, pollution amounts of DO, BOD, COD and pH increased at Memorial-bridge and pollution source site. Therefore, pollution inflow can be forecasted exactly by up/down stream relation formula at pollution source site.

Intestinal Parasites among Wild Rodents in Northern Gangwon-do, Korea

  • Lee, Young-Il;Pyeon, Hee-Jang;Seo, Min
    • Parasites, Hosts and Diseases
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    • 제51권5호
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    • pp.603-606
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    • 2013
  • To determine geographical patterns of natural parasite infections among wild rodents, a total of 46 wild rodents from 3 different localities in northern Gangwon-do (Province), Korea were examined for intestinal parasite infections. Along with nematodes such as hookworms and Syphacia spp., Plagiorchis muris (2 specimens) (Trematoda) were collected from striped field mice, Apodemus agrarius. In a Korean wood mouse, Apodemus peninsulae, the overall nematode infections were similar to A. agrarius, but an adult worm of Echinostoma hortense (Trematoda) was collected. In addition, 2 species of cestodes, i.e., Hymenolepis nana and Hymenolepis diminuta, were collected from A. agrarius. Through this survey, A. agrarius and A. peninsule were confirmed as the natural definite hosts for zoonotic intestinal helminths, i.e., P. muris, E. hortense, H. nana, and H. diminuta, in northern Gangwon-do, Korea. Considering increased leisure activities around these areas, seasonal and further comprehensive surveys on wild rodents seem to be needed to prevent zoonotic parasite infections.