1 |
Curmi, P. A., Gavet, O., Charbaut, E., Ozon, S., Lachkar-Colmerauer, S., Manceau, V., Siavoshian, S., Maucuer, A. and Sobel, A. (1999) Stathmin and its phosphoprotein family: general properties, biochemical and functional interaction with tubulin. Cell Struct. Funct. 24, 345-357.
DOI
ScienceOn
|
2 |
Lawler, S. (1998) Microtubule dynamics: if you need a shrink try stathmin/Op18. Curr. Biol. 8, R212-R214.
DOI
ScienceOn
|
3 |
Steinmetz, M. O. (2007) Structure and thermodynamics of the tubulin-stathmin interaction. J. Struct. Biol. 158, 137-147.
DOI
ScienceOn
|
4 |
Cassimeris, L. (2002) The oncoprotein 18/stathmin family of microtubule destabilizers. Curr. Opin. Cell Biol. 14, 18-24.
DOI
ScienceOn
|
5 |
Marklund, U., Larsson, N., Gradin, H. M., Brattsand, G. and Gullberg, M. (1996) Oncoprotein 18 is a phosphorylation-responsive regulator of microtubule dynamics. EMBO J. 15, 5290-5298.
|
6 |
Sobel, A., Boutterin, M. C., Beretta, L., Chneiweiss, H., Doye, V. and Peyro-Saint-Paul, H. (1989) Intracellular substrates for extracellular signaling. Characterization of a ubiquitous, neuron-enriched phosphoprotein (stathmin). J. Biol. Chem. 264, 3765-3772.
|
7 |
Sobel, A. (1991) Stathmin: a relay phosphoprotein for multiple signal transduction? Trends Biochem. Sci. 16, 301-305.
DOI
ScienceOn
|
8 |
Belletti, B. and Baldassarre, G. (2011) Stathmin: a protein with many tasks. New biomarker and potential target in cancer. Expert Opin. Ther. Targets 15, 1249-1266.
DOI
ScienceOn
|
9 |
Guy, G. R., Cao, X., Chua, S. P. and Tan, Y. H. (1992) Okadaic acid mimics multiple changes in early protein phosphorylation and gene expression induced by tumor necrosis factor or interleukin-1. J. Biol. Chem. 267, 1846-1852.
|
10 |
Tournebize, R., Andersen, S. S., Verde, F., Doree, M., Karsenti, E. and Hyman, A. A. (1997) Distinct roles of PP1 and PP2A-like phosphatases in control of microtubule dynamics during mitosis. EMBO J. 16, 5537-5549.
DOI
ScienceOn
|
11 |
Mistry, S. J., Li, H. C. and Atweh, G. F. (1998) Role for protein phosphatases in the cell-cycle-regulated phosphorylation of stathmin. Biochem. J. 334 (Pt 1), 23-29.
DOI
|
12 |
Polak, R. and Buitenhuis, M. (2012) The PI3K/PKB signaling module as key regulator of hematopoiesis: implications for therapeutic strategies in leukemia. Blood 119, 911-923.
DOI
ScienceOn
|
13 |
Yoshida, A., Zokumasu, K., Wano, Y., Yamauchi, T., Imamura, S., Takagi, K., Kishi, S., Urasaki, Y., Tohyama, K. and Ueda, T. (2012) Marked upregulation of Survivin and Aurora-B kinase is associated with disease progression in the myelodysplastic syndromes. Haematologica 97, 1372-1379.
DOI
ScienceOn
|
14 |
Martelli, A. M., Evangelisti, C., Chiarini, F., Grimaldi, C., Cappellini, A., Ognibene, A. and McCubrey, J. A. (2010) The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis. Biochim. Biophys. Acta. 1803, 991-1002.
DOI
ScienceOn
|
15 |
Wesierska-Gadek, J. and Kramer, M. P. (2012) The impact of CDK inhibition in human malignancies associated with pronounced defects in apoptosis: advantages of multi-targeting small molecules. Future Med. Chem. 4, 395-424.
DOI
ScienceOn
|
16 |
Wesierska-Gadek, J. and Maurer, M. (2011) Promotion of apoptosis in cancer cells by selective purine-derived pharmacological CDK inhibitors: one outcome, many mechanisms. Curr. Pharm. Des. 17, 256-271.
DOI
ScienceOn
|
17 |
Farag, S. S. (2011) The potential role of Aurora kinase inhibitors in haematological malignancies. Br. J. Haematol. 155, 561-579.
DOI
ScienceOn
|
18 |
Rubin, C. I., French, D. L. and Atweh, G. F. (2003) Stathmin expression and megakaryocyte differentiation: a potential role in polyploidy. Exp. Hematol. 31, 389-397.
DOI
ScienceOn
|
19 |
Iancu-Rubin, C., Nasrallah, C. A. and Atweh, G. F. (2005) Stathmin prevents the transition from a normal to an endomitotic cell cycle during megakaryocytic differentiation. Cell Cycle 4, 1774-1782.
DOI
|
20 |
Chang, C. L., Hora, N., Huberman, N., Hinderer, R., Kukuruga, M. and Hanash, S. M. (2001) Oncoprotein 18 levels and phosphorylation mediate megakaryocyte polyploidization in human erythroleukemia cells. Proteomics 1, 1415-1423.
DOI
|
21 |
Iancu-Rubin, C., Gajzer, D., Tripodi, J., Najfeld, V., Gordon, R. E., Hoffman, R. and Atweh, G. F. (2011) Down-regulation of stathmin expression is required for megakaryocyte maturation and platelet production. Blood 117, 4580-4589.
DOI
ScienceOn
|
22 |
Rabilloud, T., Berthier, R., Valette, C., Garin, J. and Lawrence, J. J. (1995) Induction of stathmin expression during erythropoietic differentiation. Cell Growth Differ. 6, 1307-1314.
|
23 |
Feuerstein, N. and Cooper, H. L. (1983) Rapid protein phosphorylation induced by phorbol ester in HL-60 cells. Unique alkali-stable phosphorylation of a 17,000-dalton protein detected by two-dimensional gel electrophoresis. J. Biol. Chem. 258, 10786-10793.
|
24 |
Johnson, W. E., Jones, N. A., Rowlands, D. C., Williams, A., Guest, S. S. and Brown, G. (1995) Down-regulation but not phosphorylation of stathmin is associated with induction of HL60 cell growth arrest and differentiation by physiological agents. FEBS Lett. 364, 309-313.
DOI
ScienceOn
|
25 |
Ramlogan-Steel, C. A., Steel, J. C., Fathallah, H., Iancu-Rubin, C., Soleimani, M., Dong, Z. and Atweh, G. F. (2012) The Role of Stathmin, a Regulator of Mitosis, in Hematopoiesis. Blood (ASH Annual Meeting Abstracts). 120, Abstract #3453.
|
26 |
Mock, B. A., Krall, M. M., Padlan, C., Dosik, J. K. and Schubart, U. K. (1993) The gene for Lap18, leukemia-associated phosphoprotein p18 (metablastin), maps to distal mouse chromosome 4. Mamm. Genome. 4, 461-462.
DOI
|
27 |
Melhem, R. F., Strahler, J. R., Hailat, N., Zhu, X. X. and Hanash, S. M. (1991) Involvement of OP18 in cell proliferation. Biochem. Biophys. Res. Commun. 179, 1649-1655.
DOI
ScienceOn
|
28 |
Hanash, S. M., Strahler, J. R., Kuick, R., Chu, E. H. and Nichols, D. (1988) Identification of a polypeptide associated with the malignant phenotype in acute leukemia. J. Biol. Chem. 263, 12813-12815.
|
29 |
Zhu, X. X., Kozarsky, K., Strahler, J. R., Eckerskorn, C., Lottspeich, F., Melhem, R., Lowe, J., Fox, D. A., Hanash, S. M. and Atweh, G. F. (1989) Molecular cloning of a novel human leukemia-associated gene. Evidence of conservation in animal species. J. Biol. Chem. 264, 14556-14560.
|
30 |
Melhem, R. F., Zhu, X. X., Hailat, N., Strahler, J. R. and Hanash, S. M. (1991) Characterization of the gene for a proliferation-related phosphoprotein (oncoprotein 18) expressed in high amounts in acute leukemia. J. Biol. Chem. 266, 17747-17753.
|
31 |
Melhem, R., Hailat, N., Kuick, R. and Hanash, S. M. (1997) Quantitative analysis of Op18 phosphorylation in childhood acute leukemia. Leukemia 11, 1690-1695.
DOI
|
32 |
Roos, G., Brattsand, G., Landberg, G., Marklund, U. and Gullberg, M. (1993) Expression of oncoprotein 18 in human leukemias and lymphomas. Leukemia 7, 1538-1546.
|
33 |
Machado-Neto, J. A., de Melo Campos, P., Favaro, P., Lazarini, M., Lorand-Metze, I., Costa, F. F., Olalla Saad, S. T. and Traina, F. (2014) Stathmin 1 is involved in the highly proliferative phenotype of high-risk myelodysplastic syndromes and acute leukemia cells. Leuk. Res. 38, 251-257.
DOI
ScienceOn
|
34 |
Jeha, S., Luo, X. N., Beran, M., Kantarjian, H. and Atweh, G. F. (1996) Antisense RNA inhibition of phosphoprotein p18 expression abrogates the transformed phenotype of leukemic cells. Cancer Res. 56, 1445-1450.
|
35 |
Marafioti, T., Copie-Bergman, C., Calaminici, M., Paterson, J. C., Shende, V. H., Liu, H., Baia, M., Ramsay, A. D., Agostinelli, C., Briere, J., Clear, A., Du, M. Q., Piccaluga, P. P., Masir, N., Nacheva, E. P., Sujobert, P., Shanmugam, K., Grogan, T. M., Brooks, S. P., Khwaja, A., Ardeshna, K., Townsend, W., Pileri, S. A., Haioun, C., Linch, D., Gribben, J. G., Gaulard, P. and Isaacson, P. G. (2013) Another look at follicular lymphoma: immunophenotypic and molecular analyses identify distinct follicular lymphoma subgroups. Histopathology 62, 860-875.
DOI
ScienceOn
|
36 |
Iancu, C., Mistry, S. J., Arkin, S., Wallenstein, S. and Atweh, G. F. (2001) Effects of stathmin inhibition on the mitotic spindle. J. Cell Sci. 114, 909-916.
|
37 |
Brattsand, G., Roos, G., Marklund, U., Ueda, H., Landberg, G., Nanberg, E., Sideras, P. and Gullberg, M. (1993) Quantitative analysis of the expression and regulation of an activation-regulated phosphoprotein (oncoprotein 18) in normal and neoplastic cells. Leukemia 7, 569-579.
|
38 |
Nylander, K., Marklund, U., Brattsand, G., Gullberg, M. and Roos, G. (1995) Immunohistochemical detection of oncoprotein 18 (Op18) in malignant lymphomas. Histochem. J. 27, 155-160.
|
39 |
Decaux, O., Lode, L., Magrangeas, F., Charbonnel, C., Gouraud, W., Jezequel, P., Attal, M., Harousseau, J. L., Moreau, P., Bataille, R., Campion, L., Avet-Loiseau, H. and Minvielle, S. (2008) Prediction of survival in multiple myeloma based on gene expression profiles reveals cell cycle and chromosomal instability signatures in high-risk patients and hyperdiploid signatures in low-risk patients: a study of the Intergroupe Francophone du Myelome. J. Clin. Oncol. 26, 4798-4805.
DOI
ScienceOn
|
40 |
Holmfeldt, P., Sellin, M. E. and Gullberg, M. (2010) Upregulated Op18/stathmin activity causes chromosomal instability through a mechanism that evades the spindle assembly checkpoint. Exp. Cell Res. 316, 2017-2026.
DOI
ScienceOn
|
41 |
Misek, D. E., Chang, C. L., Kuick, R., Hinderer, R., Giordano, T. J., Beer, D. G. and Hanash, S. M. (2002) Transforming properties of a Q18->E mutation of the microtubule regulator Op18. Cancer Cell 2, 217-228.
DOI
ScienceOn
|
42 |
Unwin, R. D., Sternberg, D. W., Lu, Y., Pierce, A., Gilliland, D. G. and Whetton, A. D. (2005) Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL. J. Biol. Chem. 280, 6316-6326.
DOI
ScienceOn
|
43 |
Shi, X., Wang, D., Ding, K., Lu, Z., Jin, Y., Zhang, J. and Pan, J. (2010) GDP366, a novel small molecule dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. Cancer Biol. Ther. 9, 640-650.
DOI
|
44 |
Phadke, A. P., Jay, C. M., Wang, Z., Chen, S., Liu, S., Haddock, C., Kumar, P., Pappen, B. O., Rao, D. D., Templeton, N. S., Daniels, E. Q., Webb, C., Monsma, D., Scott, S., Dylewski, D., Frieboes, H. B., Brunicardi, F. C., Senzer, N., Maples, P. B., Nemunaitis, J. and Tong, A. W. (2011) In vivo safety and antitumor efficacy of bifunctional small hairpin RNAs specific for the human Stathmin 1 oncoprotein. DNA Cell Biol. 30, 715-726.
DOI
ScienceOn
|
45 |
Rana, S., Maples, P. B., Senzer, N. and Nemunaitis, J. (2008) Stathmin 1: a novel therapeutic target for anticancer activity. Expert Rev. Anticancer Ther. 8, 1461-1470.
DOI
ScienceOn
|
46 |
Jiang, H., Schiffer, E., Song, Z., Wang, J., Zurbig, P., Thedieck, K., Moes, S., Bantel, H., Saal, N., Jantos, J., Brecht, M., Jeno, P., Hall, M. N., Hager, K., Manns, M. P., Hecker, H., Ganser, A., Dohner, K., Bartke, A., Meissner, C., Mischak, H., Ju, Z. and Rudolph, K. L. (2008) Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Proc. Natl. Acad. Sci. U. S. A. 105, 11299-11304.
DOI
ScienceOn
|