• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2009년도 추계학술대회 논문집
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• pp.543-544
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• 2009

• BMB Reports
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• 제44권3호
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• pp.147-157
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• 2011

The meiotic process from the primordial stage to zygote in female germ cells is mainly adjusted by post-transcriptional regulation of pre-existing maternal mRNA and post-translational modification of proteins. Several key proteins such as the cell cycle regulator, Cdk1/cyclin B, are post-translationally modified for precise control of meiotic progression. The second messenger (cAMP), kinases (PKA, Akt, MAPK, Aurora A, CaMK II, etc), phosphatases (Cdc25, Cdc14), and other proteins (G-protein coupled receptor, phosphodiesterase) are directly or indirectly involved in this process. Many proteins, such as CPEB, maskin, eIF4E, eIF4G, 4E-BP, and 4E-T, post-transcriptionally regulate mRNA via binding to the cap structure at the 5' end of mRNA or its 3' untranslated region (UTR) to generate a closed-loop structure. The 3' UTR of the transcript is also implicated in post-transcriptional regulation through an association with proteins such as CPEB, CPSF, GLD-2, PARN, and Dazl to modulate poly(A) tail length. RNA interfering is a new regulatory mechanism of the amount of mRNA in the mouse oocyte. This review summarizes information about post-transcriptional and post-translational regulation during mouse oocyte meiotic maturation.

• Nutrition Research and Practice
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• 제3권3호
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• pp.208-211
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• 2009

This study investigated the effect of vitamin $B_6$ deficiency on antioxidant enzyme activities and lipid profile in rats with exercise-induced oxidative stress. Forty eight rats were fed either a vitamin $B_6$ deficient diet (B6-) or a control diet (control) for 4 weeks and then subdivided into 3 groups: pre-exercise (PreE); post-exercise (PostE); recess after exercise (recessE). Compared to those of control group, plasma catalase and hepatic cytosol superoxide dismutase (SOD, EC 1.15.1.1) activities of B6- group were lower regardless of exercise. The ratio of reduced glutathione/oxidized glutathione (GSH/GSSG) of B6 - group was lower in PreE and there was no difference between PostE and recessE. The level of malondialdehyde (MDA) of B6- was significantly higher in PreE and PostE. High-density lipoprotein-cholesterol (HDL-C) level of B6- group was lower regardless of exercise. Atherosclerotic index of $B_6$- group was higher in PreE and there was no difference between PostE and recessE. It is suggested that a reduction in antioxidative status caused by vitamin $B_6$ deficiency may be aggravated under exercise-induced oxidative stress.

• Natural Product Sciences
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• 제5권3호
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• pp.138-141
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• 1999

The effects of Eurycoma longifolia Jack were studied in maintaining mating behavior of sexually experienced castrated male rats after dosing them with 500 mg/kg daily of E. longifolia Jack for 10 days prior to test and later continued for two weeks where the rats were then castrated. The similar dosage was then continued for 12 weeks post-castration. However, $400\;{\mu}g/day$ of testosterone was administered subcutaneously on the day of castration and lasted for 6 weeks post-castration but later raised to $800\;{\mu}g/day$ until 12 week post-castration. Tests were conducted weekly from 2-6 weeks and 8-12 weeks post-castration. Results showed that all the experimental male rats exhibited mating behavior before castration. Further results also indicated that E. longifolia Jack successfully maintained mating behavior but less than precastration level from 2-6 weeks and later increased from 8-12 weeks post-castration. Similarly, $400\;{\mu}g/day$ of testosterone was effective in maintaining mating behavior from 2-6 weeks post-castration. However, $800\;{\mu}g/day$ of testosterone managed to return the male rats to the precastration level with all male rats exhibited mating behavior from 8-12 weeks post-castration. Further results also indicated that testosterone significantly increased the penis weights (p < 0.05) as compared to the E. longifolia Jack. In conclusion, this study shows that E. longifolia Jack continued to maintain mating behavior of sexually experienced castrated male rats, giving further evidence of the folkuse of this plant as aphrodisiac.

• Geomechanics and Engineering
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• 제28권5호
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• pp.463-475
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• 2022

In the mine exploitation stage; one of the critical issues is the stability assessment of post-pillars. The instability of post-pillars leads to serious safety hazards in mining operations. The focus of this study is to assess the stability of post-pillars in the 130# stope in the central ore body at Trepça hard rock mine by employing both conventional (i.e., critical span curve) and numerical methods (i.e., FLAC3D). Moreover, a new numerical based index (i.e., Pillar Yield Ratio-PYR) was proposed. The aim of PYR index is to determine a border line between stable, potentially unstable, and failure state of post-pillars at a specific mine site. The critical value of pillar width to height ratio is 2.5 for deep production stopes (e.g., > 800 m). Results showed that pillar size, mining height and mining depth significantly have affected the post-pillar stability. The reliability of numerical based index (i.e., PYR) is verified based on empirical underground pillar stability graph developed by Lunder, 1994. The proposed pillar yield ratio index and pillar stability graph can be used as a design tool in new mining areas at Trepça hard rock mine and for other situations with similar geotechnical conditions.

• 디지털콘텐츠학회 논문지
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• 제12권2호
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• pp.233-240
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• 2011

본 연구는 외국인근로자 직업능력개발을 위하여, 외국인근로자를 대상으로 사전교육, 사후 지원에 대한 요구를 분석하고, 효과적인 외국인근로자 교육훈련 방법론으로 e-Learning의 도입 및 활용에 대한 가능성을 탐색하고자 하였다. 총 1,872명의 외국인 근로자가 본 조사에 참여하였다. 조사 내용은 첫째, 사전교육의 운영 실태, 문제점, 개선사항, 둘째, 사후지원 측면에서 직장 배치 후 교육 참여 의사와 애로사항, 셋째, e-Learning에 대한 선호도, 요구 등이었다. 연구결과, 사전교육에서 다양한 문제점이 제시되었으며, 사후지원에서 외국인근로자들은 직장생활을 하면서 교육을 받고자 하는 높은 의지를 가지고 있으나, 시간 부족, 이동 등의 문제를 애로사항으로 꼽았다. 이들은 e-Learning에 대한 높은 선호도와 요구를 보였다. 이에 작업장 이탈의 어려움을 해소시키고 상이한 교육 조건 및 수준에 따른 맞춤식의 개별화된 서비스를 제공할 수 있는 e-Learning의 가능성과 필요성이 제안되었다.

• 대한치과보철학회지
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• 제39권2호
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• pp.197-207
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• 2001

Development of new ceramics and esthetic needs of patients increase the use of all ceramic restorations. Fractured teeth often need metal post and core as foundation for final restoration. When all ceramic restorations are planned, metal post and core may lead to compromised esthetics because of opacity and gray color of metal post and core. Many techniques have been proposed to solve this problem such as application of an opaque porcelain to the metal core or all ceramic post and core. This study was performed to evaluate effect on color of Empress 2 crown according to various post systems. Color was evaluated by the CIE $L^*a^*b^*$ systems and measured by spectrophotometer (Model CM-3500, Minolta, Japan). Specimens were divided into 4 groups as follows Group 1 : gold cast post specimen + Empress 2 crown specimen Group 2 : application of an opaque porcelain to gold cast post specimen + Empress 2 crown specimen Group 3 : cosmopost specimen + Empress 2 crown specimen Group 4 : In-ceram post specimen + Empress 2 crown specimen. The results obtained as follows, 1. $L^*$ Values showed that group 2, 3, 4 were higher than group 1 with significant difference and group 2, 3, 4 were not significantly different. 2. $a^*$ Values and $b^*$ values also showed that group 2. 3, 4 were higher than group 1 with significant difference and group 2, 3, 4 were not significantly different. 3. ${\Delta}E^* ab$ Values showed that ${\Delta}E^* ab$ 3 was the highest value and ${\Delta}E^* ab$ 5 was the lowest value.

• The Journal of Asian Finance, Economics and Business
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• 제6권1호
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• pp.129-139
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• 2019

The purpose of this research is to examine the effect of informational justice on post-recovery satisfaction, and the effect of post-recovery satisfaction on behavioral intentions in e-commerce, including further investigate the moderating effect of service failure severity. Using quantitative method, the population of this research are online customers in Indonesia, with non-probability sampling that will be done by purposive sampling method based on predetermined criterias, which are customers who were doing transactions in the Business to Consumer (B2C) online sites, experienced service failure in the last 6 months, submitted a complaint, and received a response. Sample of 317 online customers were gathered and analyzed using the Structural Equation Modeling. The results of this study indicated that 5 hypothesis are supported with data. As a conclusion, informational justice and post-recovery satisfaction has positive effect, while service failure severity acts as a moderator between post-recovery satisfaction and behavioral intentions. As a managerial implication, online store management needs to ensure the informational justice to make a post-recovery satisfaction. Therefore, online store management needs to ensure the informational justice to make a post-recovery satisfaction, increase repurchase and positive e-word of mouth intention, also work harder to recover services, especially in high service failure severity condition.

• 한국IT서비스학회지
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• 제12권4호
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• pp.59-75
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• 2013

As education environment is changing rapidly and competition of education industry is more intensive, the importance of service view about education is increasing as a differential competitive advantage. This study attempted to investigate the impact of service convenience as a different competitive advantage on e-learning acceptance by using TAM. The purpose of this study is to examine how five-dimensional service convenience constructs(decision convenience, access convenience, transaction convenience, benefit convenience, post-benefit convenience) affect consumers' perceived usefulness, attitude and usage intention. For this study, data were gathered from respondents who bought or used e-learning services and analyzed by structural equation model. Among the five-dimensional service convenience constructs, two constructs(benefit convenience, post-benefit convenience) affected consumers' positive perceived usefulness, attitude and usage intention about e-learning service. The results show that management and investment to improve benefit and post-benefit service convenience make consumers' positive attitude and usage intention about e-learning service.

• 유통과학연구
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• 제17권1호
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• pp.47-56
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• 2019

Purpose - This case study illustrates the story of eBay Korea, which owns two most leading Korean open market companies, AUCTION and Gmarket. The main concerns are to take over the Korean top domestic companies one by one, then, emerge these two giants through its well-developed post-merger Integration by eBay, an American multinational corporation. Research design, data, and methodology - This case explores various secondary resources such as periodicals, annual reviews, magazine, news articles, commentaries, even some interview materials related to 'eBay Korea' and industry source on condition of anonymity based on the critical reviewing of existing studies on these topics as well. Results - The findings of this study show the merger and acquisition of two market leaders in Korea is the only successful case in Asian Markets. The eBay's choice of entry mode is appropriate considering the timing, synergy and efficiency by sharing their resources. Conclusions - This study examines the successful entry and settlement process of foreign, multinational company through mergers and acquisitions in the Korean market. This would be a valuable in the studies of International Business and Global entry or distribution strategy in the e-commerce and open market dealing with M&A and its post-merger integration.