• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2022년도 학술발표회
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• pp.156-156
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• 2022

Explicitly spatially distributed and reliable data on industrial water demand is very much important for both policy makers and researchers in order to carry a region-specific analysis of water resources management. However, such type of data remains scarce particularly in underdeveloped and developing countries. Current research is limited in using different spatially available socio-economic, climate data and geographical data from different sources in accordance to predict industrial water demand at finer resolution. This study proposes a random forest regression (RFR) model to predict the industrial water demand at 0.50× 0.50 spatial resolution by combining various features extracted from multiple data sources. The dataset used here include National Polar-orbiting Partnership (NPP)/Visible Infrared Imaging Radiometer Suite (VIIRS) night-time light (NTL), Global Power Plant database, AQUASTAT country-wise industrial water use data, Elevation data, Gross Domestic Product (GDP), Road density, Crop land, Population, Precipitation, Temperature, and Aridity. Compared with traditional regression algorithms, RF shows the advantages of high prediction accuracy, not requiring assumptions of a prior probability distribution, and the capacity to analyses variable importance. The final RF model was fitted using the parameter settings of ntree = 300 and mtry = 2. As a result, determinate coefficients value of 0.547 is achieved. The variable importance of the independent variables e.g. night light data, elevation data, GDP and population data used in the training purpose of RF model plays the major role in predicting the industrial water demand.

• Food Science and Biotechnology
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• 제17권2호
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• pp.384-388
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• 2008

Alzheimer's disease (AD) is the most common neurodegenerative disorder and is responsible for more than 50% of all dementia cases. There is significant interest in finding new sources of compounds that inhibit acetylcholinesterase (AChE) to be used in the treatment of AD, since only a few AChE inhibitors, such as galanthamine, physostigmine, and tacrine, are available for clinical use. In the present study, ICR mice were treated with a 1 mg/kg scopolamine, which caused impaired cognitive ability. The steady consumption of a water extract of Chrysanthemum indicum Linne flowers for 3 months significantly prevented the scopolamine induced deficit of the spatial cognitive capability of mice. It also improved long-term memory in mice with amnesia induced by scopolamine, as assessed by the Morris water maze and passive avoidance tests. In addition, water extract consumption significantly decreased AChE activity in mouse brain, leading to inhibition of acetylcholine hydrolysis.

• 한국과학교육학회지
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• 제42권2호
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• pp.227-238
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• 2022

과학 교사의 주요한 역할 중 하나는 학생들이 과학 수업의 주체로서 활발하게 참여할 수 있도록 돕는 것이다. 이와 관련하여 본 연구에서는 한 초등학교 과학 전담 교사가 어떻게 학생들의 정서적 자원을 활용하여 정서적 반응적 교수를 수행하였고 그 결과는 무엇이었는지 기술하였다. 연구의 참여자는 교사 자신과 그가 가르치고 있는 6학년 학생들이었으며, '다양한 생물과 우리 생활' 단원의 수업에 교사의 정서적 반응적 교수가 적용되었다. 교사의 개인 일지, 수업 녹화본, 학생들과의 면담을 포함한 다양한 종류의 자료를 수집하였으며, 이들을 질적인 방법으로 분석하고, 셀프 스터디의 방식으로 연구 결과를 기술하였다. 교사는 학생들의 세 가지 정서적 자원(캐릭터 그리기, 티셔츠 디자인, 랩)을 활용하여 정서적 반응적 교수를 수행하였다. 교사의 정서적 반응적 교수는 학생들의 긍정적인 정서 및 활발한 수업 참여, 지식의 탐색과 정당화를 포함하는 인식적 실천, 일상생활의 맥락을 고려한 지식의 재구성이라는 효과를 가져왔다. 이에 따라 정서적 반응적 교수가 초등학생들의 과학 수업 참여를 촉진하면서 정서적, 인식적, 개념적 측면에서 유의미한 학습 결과를 가져올 수 있음을 논의하였다. 따라서 정서적 반응적 교수의 특징과 세부 교수 전략들을 이해하기 위한 후속 연구가 수행되어야 할 것이다.

• 한국초등과학교육학회지:초등과학교육
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• 제32권3호
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• pp.361-377
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• 2013

The purposes of this study were to develop STEAM teaching materials about 'world of small organisms' unit on elementary science education and to apply lesson using them for the 5th and 6th graders. Compared to other STEAM programs studied previously, the STEAM teaching materials of this study includes students' STEAM, teachers' guide, story-telling books and multimedia teaching aids consisted of practical resources to manage STEAM lessons. The whole program was designed from multidisciplinary integration to extradisciplinary integration through activities making creative products, meanwhile each period had discretionary S, T, E, A, M factors specifically. To examine the effects of integrated lesson on scientific knowledge, process skills, and affective domain, the study subjects were divided into two groups. The experimental group was composed of 69 individuals participated in STEAM lesson, while students of the control group were 67 individuals learned through general learning methods. The developed STEAM teaching materials affected significantly on scientific knowledge and affective domain of elementary school students, but process skills were not increased significantly. In the present study, therefore, the approach applying STEAM education could be suggested as alternative learning materials or supplementary teaching materials at the field of small organisms in elementary science sufficiently.

• International Journal of Computer Science & Network Security
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• 제22권5호
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• pp.182-192
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• 2022

All the aspects of human life have been affected by the novel coronavirus (Covid-19). It has rapidly spread in most countries including the Kingdom of Saudi Arabia. As a result, early precautionary actions aiming to minimise the virus effect are taken by the Saudi government. One of these actions is the sudden shift to online classes and suspending the attendees to all educational institutes. Such immediate change can have a significant effect on the educational process, especially for students. One can argue that students' information-seeking behaviour within the current situation can affect their learning quality and outcomes. Therefore, this paper examines the Saudi students' information-seeking behaviour by taking a sample of students from Umm Al-Qura University. A descriptive analysis is conducted with 193 students and two approaches are used to collect data, questionnaire and semi-structured interview. The results showed that the majority of students face difficulties when searching and retrieving e-resources from the university library website. The problems range from mainly poor User Experience (UX), network connection, multiple errors and lack of subscription with academic publishers.

• 한국식품영양과학회지
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• 제34권5호
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• pp.738-742
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• 2005

고령화 현상에 의한 노인 인구의 증가에 따라 노인성 질환연구의 중요성이 대두되고 있으며, 특히 노인성 질환 중 가장 문제되는 치매(dementia)에서 노인성 치매(Alzhemier's disease)는 복합적 인 원인에 의 해서 나타나므로 다양한 관점에서의 연구가 필요하다. 따라서 본 연구에서는 마우스에 scopolamin(30 mg/kg BW)을 투여하여 기억${\cdot}$학습장애를 유발하고, 뇌조직의 아세틸콜린 및 그 관련 효소에 미치는 도토리 분말의 영향을 분석하였다. 뇌의 가장 중요한 신경전달 물질로서 아세틸콜린 생성에 미치는 도토리 분말 투여효과를 비교하였을 때, AP-5및 AP-10 투여군에서 $4.2\%$ 및 $11.3\%$의 ACh 합성이 증가하는 경향이 나타났으며, ACh의 분해효소인 acetylcholinesterase(AChE)의 활성은 AP-5 및 AP-10의 도토리 분말 투여군에서 $13.5\%$ 및 $17.6\%$로서 AChE효소활성이 유의적으로 감소하였다. 그리고 카테롤아민계 신경전달물질의 파괴에 관계하는MAO-B효소의 활성은 AP-5 및 AP-10의 도토리 분말 투여군에서 $10.0\%$ 및 $12.7\%$로서 도토리 분말 투여에 의해 MAO-B효소활성이 현저하게 억제되었다. 따라서 도토리는 AChE 효소의 활성을 저해하여 ACh의 농도를 높일 뿐만 아니라 MAO-B효소의 활성을 효과적으로 억제하여 카테콜아민계 신경전달물질을 잘 보존함으로써 치매 예방에 도움이 될 것으로 기대된다.

• Asia Marketing Journal
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• 제15권3호
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• pp.79-95
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• 2013

New product innovation is a process of embodying new knowledge in a product and technology licensing is getting popular as a means to innovations and introduction of new product to the market in today's competitive global market environment. Incumbents often rely on technology licensing to access new product opportunities created by other firms. Prior research has examined various aspects of technology licensing agreements such as specific contract terms of licensing agreements, e.g., distribution of control rights, exclusivity of licensing agreements, cross-licensing, and the scope of licensing agreements. This study aims to provide answers to an important, but under-researched question: why do some incumbents initiate more licensing agreement for exploratory learning while others do it for exploitative learning along the innovation process? We attempt to extend our knowledge of licensing agreements from an organizational learning perspective. Technology licensing as a specific form of interfirm linkages can be initiated with different learning objectives along the process of new product innovation. The exploratory stages of the innovation process such as discovery or research stages involve extensive searches to create new knowledge or capabilities, whereas the exploitative stages of the innovation process such as application or test stages near the commercialization are more focused on developing specific applications or improving their efficiency or reliability. Thus, different stages of the innovation process generate different types of learning and the resulting technological resources. We examine when incumbents as licensees initiate more licensing agreements for exploratory learning objectives and when more for exploitative learning objectives, focusing on two factors that may influence a firm's formation of exploratory and exploitative licensing agreements: 1) its past radical and incremental innovation experience and 2) its internal investments in R&D and marketing. We develop and test our hypotheses regarding the relationship between a firm's radical and incremental new product experience, R&D investment intensity and marketing investment intensity, and the likelihood of engaging in exploratory and exploitive licensing agreements. Using data collected from various secondary sources (Recap database, Compustat database, and FDA website), we analyzed technology licensing agreements initiated in the biotechnology and pharmaceutical industries from 1988 to 2011. The results of this study show that incumbents initiate exploratory rather than exploitative licensing agreements when they have more radical innovation experience and when they invest in R&D activities more intensively; in contrast, they initiate exploitative rather than exploratory licensing agreements when they have more incremental innovation experience and when they invest in marketing activities more intensively. The findings of this study contribute to the licensing and interfirm cooperation studies. First, this study lays a foundation to understand the organizational learning aspect of technology licensing agreements. Second, this study sheds lights on how a firm's internal investments in R&D and marketing are linked to its tendency to initiate licensing agreements along the innovation process. Finally, the findings of this study provide important insight to managers regarding which technologies to gain via licensing agreements. This study suggests that firms need to consider their internal investments in R&D and marketing as well as their past innovation experiences when they initiate licensing agreements along the process of new product innovation.

• 한국축산식품학회지
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• 제40권2호
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• pp.183-196
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• 2020

The protective effect of pig skin gelatin water extracts (PSW) and the low molecular weight hydrolysates of PSW generated via enzymatic hydrolysis with Flavourzyme® 1000L (LPSW) against scopolamine-induced impairment of cognitive function in mice was determined. Seventy male ICR mice weighing 20-25 g were randomly assigned to seven groups: Control (CON); scopolamine (SCO, 1 mg/kg B.W., intraperitoneally (i.p.); tetrahydroaminoacridine 10 [THA 10, tacrine; 10 mg/kg B.W. per oral (p.o.) with SCO (i.p.)]; PSW 10 (10 mg/kg B.W. (p.o.) with SCO (i.p.); PSW 40 (40 mg/kg B.W. (p.o.) with SCO (i.p.); LPSW 100 (100 mg/kg B.W. (p.o.) with SCO (i.p.); LPSW 400 (400 mg/kg B.W. (p.o.) with SCO (i.p.). All treatment groups, except CON, received scopolamine on the day of the experiment. The oxygen radical absorbance capacity of LPSW 400 at 1 mg/mL was 154.14 μM Trolox equivalent. Administration of PSW and LPSW for 15 weeks did not significantly affect on physical performance of mice. LPSW 400 significantly increased spontaneous alternation, reaching the level observed for THA and CON. The latency time of animals receiving LPSW 400 was higher than that of mice treated with SCO alone in the passive avoidance test, whereas it was shorter in the water maze test. LPSW 400 increased acetylcholine (ACh) content and decreased ACh esterase activity (p<0.05). LPSW 100 and LPSW 400 reduced monoamine oxidase-B activity. These results indicated that LPSW at 400 mg/kg B.W. is a potentially strong antioxidant and contains novel components for the functional food industry.

• 한국콘텐츠학회논문지
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• 제21권5호
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• pp.129-138
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• 2021

오늘날 우리는 인터넷을 통하여 웹사이트에서 다양한 활동과 많은 정보를 얻고 있다. 이러한 웹사이트들은 개인 또는 웹사이트 전문업체에 의해 유지보수되며, 기본적인 방법은 운영되고 있는 웹사이트를 구성하고 있는 파일들을 변경하는 것이다. 이 과정에서 전체 파일을 변경하는 것은 시간이 오래 걸리고, 변경하지 않아도 되는 파일들까지 변경하므로 효율성이 많이 떨어진다. 반대로 변경해야 하는 파일들만 변경하게 될 경우, 사람이 직접 각 경로를 탐색하여 파일들을 확인하고 하나씩 파일을 변경해야 하므로 손이 많이 간다. 이를 해결하고자 자동 배포 시스템들이 개발되었으나, 추가적인 자원과 학습이 필요하며 비용과 시간, 노동력이 추가로 발생한다. 이에 본 논문에서는 기존 웹사이트의 자원과 기술을 사용하여, 자원 소모를 최소화하고, 새로운 기술의 학습이 필요 없는 자동 업데이트 시스템을 제안하고자 한다. 이를 통해 사람의 작업 대비 신뢰성과 시간을 향상하는 것을 목적으로 한다.

• Advances in Computational Design
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• 제7권2호
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• pp.113-128
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• 2022

Water consumption is strongly affected by numerous factors, such as population, climatic, geographic, and socio-economic factors. Therefore, the implementation of a reliable predictive model of water consumption pattern is challenging task. This study investigates the performance of predictive models based on multi-layer perceptron (MLP), multiple linear regression (MLR), and support vector regression (SVR). To understand the significant factors affecting water consumption, the stepwise regression (SW) procedure is used in MLR to obtain suitable variables. Then, this study also implements three predictive models based on these significant variables (e.g., SWMLR, SWMLP, and SWSVR). Annual data of water consumption in Thailand during 2006 - 2015 were compiled and categorized by provinces and distributors. By comparing the predictive performance of models with all variables, the results demonstrate that the MLP models outperformed the MLR and SVR models. As compared to the models with selected variables, the predictive capability of SWMLP was superior to SWMLR and SWSVR. Therefore, the SWMLP still provided satisfactory results with the minimum number of explanatory variables which in turn reduced the computation time and other resources required while performing the predictive task. It can be concluded that the MLP exhibited the best result and can be utilized as a reliable water demand predictive model for both of all variables and selected variables cases. These findings support important implications and serve as a feasible water consumption predictive model and can be used for water resources management to produce sufficient tap water to meet the demand in each province of Thailand.