• Title/Summary/Keyword: E Ink

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Methylation of p16 and E-cadherin in ameloblastoma (법랑아세포종에서 p16과 E-cadherin의 메틸화)

  • Park, Can-Woong;Yoon, Hye-Kyoung;Park, Sang-Jun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.36 no.6
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    • pp.453-459
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    • 2010
  • Introduction: Ameloblastic carcinoma is a rare malignant lesion, and may arise from either carcinoma ex-ameloblastoma or de novo carcinoma. Aberrant promoter hypermethylation of the tumor-associated genes leading to their inactivation is a common event in many cancer types. The p16/CDKN2/INK4A gene and p16 5 protein are involved directly in regulating the cell cycles. Cadherins are cell adhesion molecules that modulate the epithelial phenotype and regulate tumor invasion. The aim of this study was to evaluate the roles of p16 and E-cadherin methylation and loss of p16 and E-cadherin expression in the malignant transformation of an ameloblastoma. Materials and Methods: Eight cases of ameloblastoma, including 4 benign ameloblastomas without recurrence, 2 benign ameloblastomas with recurrence and 2 carcinoma ex-ameloblastomas, were examined. The promoter hypermethylation profile of the p16 and E-cadherin genes was studied using methylation-specific polymerase chain reaction (MSP) and immunohistochemical staining for p16 and E-cadherin expression. Results: 1) Aberrant CpG island methylation of the p16 gene was detected in 3 of the 4 benign ameloblastomas without recurrence and 1 of the 2 benign ameloblastomas with recurrence. 2) Aberrant CpG island methylation of the E-cadherin gene was found in 1 of the 4 benign ameloblastomas without recurrence. 3) A loss of p16 expression was noted in 1 of 4 benign ameloblastomas without recurrence and 1 of 2 carcinoma ex-ameloblastomas. 4) A loss of E-cadherin expression was noted in 2 of the 4 benign ameloblastomas without recurrence, 1 of the 2 benign ameloblastomas with recurrence and 2 of the 2 carcinoma ex-ameloblastomas. 5) A loss of p16 expression was observed in 1 of the 4 cases showing aberrant methylation of the p16 gene. 6) A loss of E-cadherin expression was observed in 3 benign ameloblastoma case showing aberrant methylation of the E-cadherin gene. Conclusion: These results suggest that loss of E-cadherin expression related to the other genetic pathway (not methylation) might be an adjuvant indicator predicting the malignant transformation of an ameloblastoma. However, the number of samples in this study was too small and the relationship between the treatment methods and clinical course were not defined. Therefore, further study will be needed.

Effect of PDMS Blanket Deformation on Printability in Reverse-Offset Printing (리버스 옵셋 인쇄에서 PDMS 블랑켓 변형이 인쇄에 미치는 영향에 관한 연구)

  • Choi, Young-Man;Kim, Kwang-Young;Jo, Jeongdai;Lee, Taik-Min
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.38 no.8
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    • pp.709-714
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    • 2014
  • Reverse-offset printing is one of the technologies that can be used for patterning fine features of the order of a few micrometers for printed electronics. In reverse-offset printing, a coated ink film is transferred to a blanket made of elastomer-like poly-dimethylsiloxane. Then, the blanket is impressed onto a clich$\acute{e}$ that has intaglio patterns. The blanket is deformed by penetrating the intaglio of the clich$\acute{e}$ according to the printing pressure. Excessive deformation of the blanket can cause printing defects upon touching the bottom of the intaglio pattern, especially in large patterns. In this paper, we modelled the deformation of the blanket using the finite element method. Considering the actual printing parameters, a condition for fabricating a clich$\acute{e}$ is proposed to prevent defects by the deformation of the blanket.

Effects on Printing Quality according to Yarn Twist and Knitting Structure of Media in Digital Textile Printing(II) (DTP(Digital Textile Printing)에서 미디어의 원사꼬임 및 편성구조가 프린팅 Quality에 미치는 영향(2))

  • Park, Soon-Young;Jeon, Dong-Won;Park, Yoon-Cheol;Lee, Beom-Soo
    • Textile Coloration and Finishing
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    • v.23 no.1
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    • pp.35-42
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    • 2011
  • For high quality DTP products, it is important to optimize the parameters of media, pre- and after-treatment, ink, printer, etc. This study investigated the effect of types of fabrics(media) as a DTP parameters. Especially, the effects of media properties such as yarn twist and knitted fabric structure, on printability and color difference were examined. Two types of cotton yarn twist(830 and 1630 twist/meter) and five knitted structures of media were prepared with a single circular knitting machine. The K/S values of hard-twist samples were higher than those of normal-twist samples in every media structures. It is more effective to use the knitted fabrics of a hard-twist yarn to obtain dark color in the printing above input level value 60 where the printability improvement was most pronounced in case of plain structure. Among the five media structures a plain structure was the highest and that of corduroy was the lowest in terms of K/S values. Also ${\Delta}E$ values and lightness of the hard-twist yarn samples were smaller than that of normal-twist yarn samples when ${\Delta}E$ values were tested by using a standard of a normal twist yarn sample with a plain structure, which was increased in the case of corduroy structure.

Micropattern Arrays of Polymers/Quantum Dots Formed by Electrohydrodynamic Jet (e-jet) Printing (이젯 프린터를 사용한 고분자/퀀텀닷 마이크로 패터닝 공정)

  • Kim, Simon;Lee, Su Eon;Kim, Bong Hoon
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.35 no.1
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    • pp.18-23
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    • 2022
  • Electrohydrodynamic jet (e-jet) printing, a type of direct contactless microfabrication technology, is a versatile fabrication process that enables a wide range of micro/nanopattern arrays by applying a strong electric field between the nozzle and the substrate. In general, the morphology and the thickness of polymers/quantum dot micropatterns show a systematic dependence on the diameter of the nozzle and the ink composition with a fully automated printing machine. The purpose of this report is to provide typical examples of e-jet printed micropatterns of polymers/quantum dots to explain the effect of each process variable on the result of experiments. Here, we demonstrate several operating conditions that allow high-resolution printing of layers of polymers/quantum dots with a precise control over thickness and submicron lateral resolution.

Study on the Fabrication of Ultrathin Punch (초미세 천공 펀치의 성형에 대한 연구)

  • Im, Hyeong-Jun;Im, Yeong-Mo;Kim, Su-Hyeon;Gwak, Yun-Geun
    • Journal of the Korean Society for Precision Engineering
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    • v.17 no.12
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    • pp.145-150
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    • 2000
  • Micro punching is one of general methods to fabricate simple holes such as permanent ink-jet printer nozzles. A thin punch, that is need for micro punching, usually has been obtained by mechanical machining. There are some method to obtain a thin punch from a cylindrical rod, e.g., microgrinding and WEDG (Wire Electro-Discharge Grinding). Inefficiently, only one punch can be obtained from these machining methods. In contrast with these methods, many punches can be fabricated simultaneously by electrochemical process. Electrochemical process has usually aimed to obtain very sharp probe for atomic force microscopy (AFM) or scanning tunneling microscopy (STM), and it has not been considered the whole shape of a probe in spite of good merits. In this paper, an ultrathin punch with a tapered shape and a cylindrical tip is newly fabricated by electrochemical process.

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Effect of Electrode Space on Optical Property in Three-Electrode Type E-paper Display (3전극형 전자종이 디스플레이에서 하부전극 간격이 패널의 광특성에 미치는 영향)

  • Lee, Sang-il;Hong, Youn-Chan;Kim, Young-cho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.29 no.4
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    • pp.231-236
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    • 2016
  • A three-electrode type reflective display (electronic paper) is designed to apply an independent electric field to each three electrodes of the cell including two electric-type of particles and electrically neutral color fluid, so single color realization is possible. In particular, the movement of particles and optical properties are decided by the electric field between two electrodes on the lower substrate. So, the effect of electric field by the distance between two electrodes on the lower substrate is studied with electrode spacing with $10{\mu}m$, $15{\mu}m$, $20{\mu}m$, and $25{\mu}m$. By our experimentation, the driving voltage induces more reliable movement of charged particles and the optical properties as compared with the threshold voltage. We ascertain the single color realization and non-inverted particle separation is possible. So the more desirable optical properties are observed in case of the short electrode like $10{\mu}m$.

Flexible Microelectronics; High-Resolution Active-Matrix Electrophoretic Displays

  • Miyazaki, Atsushi;Kawai, Hideyuki;Miyasaka, Mitsutoshi;Nebashi, Satoshi;Shimoda, Tatsuya;McCreary, Michael
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07a
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    • pp.575-579
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    • 2005
  • A beautiful, flexible active-matrix electrophoretic display (AM-EPD) device is reported. The flexible AM-EPD device has a $40.0{\times}30.0\;mm^2$ display area, measures about 0.27 mm in thickness, weighs about 0.45 g and possesses only 20 external connections. The flexible AM-EPD device displays clear black-and-white images with 5 gray-scales on $160{\times}120$ pixels. The display is free from residual image problems, because we use an area-gray-scale method on $320{\times}240$ EPD elements, each of which is driven with binary signals. Each pixel consists of 4 EPD elements. In addition, since the response time of the electrophoretic material is as long as approximately 400 ms and since the display possesses a large number of EPD elements, we have developed a special driving method suitable for changing EPD images comfortably. A complete image is formed on the AM-EPD device, consisting of a reset frame and several, typically 6, image frames.

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Carbon Particle-Doped Polymer Layers on Metals as Chemically and Mechanically Resistant Composite Electrodes for Hot Electron Electrochemistry

  • Habiba, Nur-E;Uddin, Rokon;Salminen, Kalle;Sariola, Veikko;Kulmala, Sakari
    • Journal of Electrochemical Science and Technology
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    • v.13 no.1
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    • pp.100-111
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    • 2022
  • This paper presents a simple and inexpensive method to fabricate chemically and mechanically resistant hot electron-emitting composite electrodes on reusable substrates. In this study, the hot electron emitting composite electrodes were manufactured by doping a polymer, nylon 6,6, with few different brands of carbon particles (graphite, carbon black) and by coating metal substrates with the aforementioned composite ink layers with different carbon-polymer mass fractions. The optimal mass fractions in these composite layers allowed to fabricate composite electrodes that can inject hot electrons into aqueous electrolyte solutions and clearly generate hot electron- induced electrochemiluminescence (HECL). An aromatic terbium (III) chelate was used as a probe that is known not to be excited on the basis of traditional electrochemistry but to be efficiently electrically excited in the presence of hydrated electrons and during injection of hot electrons into aqueous solution. Thus, the presence of hot, pre-hydrated or hydrated electrons at the close vicinity of the composite electrode surface were monitored by HECL. The study shows that the extreme pH conditions could not damage the present composite electrodes. These low-cost, simplified and robust composite electrodes thus demonstrate that they can be used in HECL bioaffinity assays and other applications of hot electron electrochemistry.

3D Printing of Materials and Printing Parameters with Animal Resources: A Review

  • Eun Young Jeon;Yuri Kim;Hyun-Jung Yun;Bum-Keun Kim;Yun-Sang Choi
    • Food Science of Animal Resources
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    • v.44 no.2
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    • pp.225-238
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    • 2024
  • 3D printing technology enables the production of creative and personalized food products that meet consumer needs, such as an attractive visual appearance, fortification of specific nutrients, and modified textures. To popularize and diversify 3D-printed foods, an evaluation of the printing feasibility of various food pastes, including materials that cannot be printed natively, is necessary. Most animal resources, such as meat, milk, and eggs, are not inherently printable; therefore, the rheological properties governing printability should be improved through pre-/post-processing or adding appropriate additives. This review provides the latest progress in extrusion-based 3D printing of animal resource-based inks. In addition, this review discusses the effects of ink composition, printing conditions, and post-processing on the printing performance and characteristics of printed constructs. Further research is required to enhance the sensory quality and nutritional and textural properties of animal resource-based printed foods.

Research on Continuous After-Treatment Process and System for DTP(Digital Textile Printing) (DTP(Digital Textile Printing)용 후처리 및 연속공정 시스템에 관한 연구)

  • Park, Soon-Young;Jeon, Dong-Won;Park, Yoon-Cheol;Lee, Beom-Soo;Cho, Hang-Sung
    • Journal of Fashion Business
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    • v.15 no.5
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    • pp.43-54
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    • 2011
  • Digital Textile Printing(DTP) is appropriate for quick response system(QRS) and is closely connected with high value added fashion industry. Fashion products of high price are mainly silk and cotton. For high quality DTP products, it is important to optimize the parameters of media, pre and after-treatment, ink, printer, etc. DTP for these two fiber materials is also accompanied certainly with steaming as after-treatment process for coloration. Role of steam is like water in exhaustion dyeing. Steam can diffuse dye or ink in printing paste to fiber. Quality of DTP products depend on after-treatment processes such as steaming, washing, drying. Current production amount of DTP is smaller than one of conventional textile printing. However conventional after-treatment system has been using so far. This is mismatched with DTP in terms of process efficiency, spot work of small lot, quality control. In this study, continuous after-treatment system has been suitably designed for DTP that washing and drying are available after steaming. So, It is possible to improve efficiency of DTP process. Especially, the effects of after-treatment process, such as temperature of heat drum, steaming time on printability, color difference, color fastness were examined. Two types of samples(cotton knit and silk fabrics) were used. The results were obtained as follows : First, there is no a wide difference between the K/S values of cotton and silk treated with continuous after-treatment system and those of sample treated with conventional printing after-treatment method. So it is more effective to use the continuous after-treatment system than conventional printing after-treatment system in case of the daily throughput of 1,000 yards below. Second, after continuous after-treatment for DTP, K/S values were increased and lightness($L^*$) values were decreased. ${\Delta}E$ values were below 2.3. Third, DTP samples treated with continuous after-treatment system were tested for fastness(washing, light, rubbing). Grades of fastness(washing, light, rubbing) were above 3 grade.