• Korean Circulation Journal
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• 제52권10호
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• pp.755-767
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• 2022

Background and Objectives: Cryoballoon catheter ablation for the treatment of patients with symptomatic atrial fibrillation (AF) has been adopted globally, but there are limited multicenter reports of 12-month outcomes in the Korean patient population. This analysis evaluated the clinical performance and safety of cryoballoon ablation (CBA) according to standard-of-care practices in Korea. Methods: This evaluation of Korean patients with AF was conducted within the larger Cryo Global Registry, which is a prospective, multicenter, post-market registry. Freedom from a ≥30-second recurrence of atrial arrhythmias (after a 90-day blanking period until 12 months) and procedural safety were examined in subjects treated with CBA at 3 Korean centers. Results: Overall, 299 patients with AF (60±11 years old, 24.7% female, 50.5% paroxysmal AF) underwent CBA using the Arctic Front Advance cryoballoon. Of those, 298 were followed-up for at least 12 months. Mean procedure-, left atrial dwell- and fluoroscopy time was 76±21 minutes, 56±23 minutes, and 27±23 minutes, respectively. Freedom from AF recurrence at 12 months was 83.9% (95% confidence interval [CI], 76.9-88.9%) in the paroxysmal and 61.6% (95% CI, 53.1-69.0%) in the persistent AF cohort. Rhythm monitoring was performed on average 4.7±1.4 times during the follow-up period. Serious device- or procedure-related adverse events occurred in 2 patients (0.7%). The 12-month Kaplan-Meier estimate of freedom from repeat ablation and cardiovascular-related hospitalization was 93.8% (95% CI, 90.4-96.1%) and 89.7% (95% CI, 85.6-92.7%), respectively. Conclusions: CBA is an efficient, effective, and safe procedure for the treatment of AF patients when used according to real-world practices in Korea.

• 산업진흥연구
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• 제9권3호
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• pp.155-161
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• 2024

본 연구는 국내 모바일 커머스 내 게임화 요소인 보상형 미니게임의 사용자 경험에 관한 연구이다. 최근 모바일 커머스 서비스에 고객 유입, 체류시간 증가, 재방문율 향상의 목적으로 게임화 마케팅 전략이 적극적으로 도입되고 있다. 이에 본 연구는 게임화 요소의 사용자 경험을 연구하고, 사용자가 모바일 커머스의 게임화 요소에 대해 어떻게 느끼는지에 대한 평가를 수치화하였다. 연구 방법으로는 즐거움, 몰입, 보상, 가치성, 유용성을 기준으로 설문지를 작성하여 설문조사를 실시하고, 그중 20~40대 남녀 사용자를 대상으로 1:1 심층 인터뷰를 진행하였다. 실험 결과 즐거움과 몰입에서 사용자 만족도를 높일 수 있는 전략이 필요하며, 예측할 수 있는 보상 시스템과 상품 탐색에 관한 사용자 경험을 개선하여 상품 구매로 연결할 수 있는 전략이 필요함을 알 수 있었다. 본 연구가 게임화 요소를 적용하려는 기업의 마케팅 전략 수립 및 사용자 경험 개선에 시사점을 줄 수 있기를 기대한다.

• 한국콘텐츠학회논문지
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• 제9권2호
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• pp.309-317
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• 2009

본 연구는 뇌손상 흰쥐에서 기억과 학습훈련을 통해 인지기능회복과 해마의 신경 성장인자에 미치는 영향을 알아보고자 하였다. 뇌손상은 Sprague-Dawley계 흰쥐 36마리를 중대뇌동맥(middle cerebral artery)을 폐색하여 유발하였고, 실험 군들은 3개 군으로 분류하였다; 실험 군 I은 뇌손상유발 군(n=12), 실험 군 II는 뇌손상 유발 후 트레드밀훈련 군(n=12), 실험 군 Ⅲ은 뇌손상 유발 후 기억과 학습훈련 군(n=12)으로 나누었다. 인지기능 검사를 위해 수중모리스미로 습득검사와 파지검사를 실시하였으며, 조직학적 검사는 해마조직의 BDNF(brain-derived neurotrophic factor) 면역조직화학 반응을 관찰하였다. 수중모리스미로 습득 검사(Morris water maze acquisition test)는 시간과 군사이의 교호작용이 유의한 차이가 나타났고(p<.001), III군에서 9일에서 12일째까지 원형도피대를 찾는 시간이 I, II군에 비해 단축되었다. 수중모리스미로 파지검사(retention test)는 군 사이에서도 유의한 차이가 나타났으며(p<.001), 13일째 III군에서 원형도피대가 있었던 사분원에 배회하는 시간이 가장 길었다. 조직학적 검사는 III군에서 7일째 해마조직의 CA1에서 BDNF의 면역조직화학반응이 I, II군에 비해 면역양성반응의 증가를 관찰하였다. 뇌손상 흰쥐에서 기억과 학습훈련이 신경성장인자 발현 변화와 이로 인한 신경연접 가소성의 변화를 통해 인지기능회복에 더 좋은 영향을 주었다.

• 대한교통학회지
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• 제25권3호
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• pp.145-154
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• 2007

대중교통 시스템의 운행계획 수립과정에서 정류장의 간격과 위치설정은 매우 중요한 문제이다. 본 연구에서는 해석적인 방법을 통해 정류장의 간격과 위치를 결정하는 방법론을 제시하였다. 정류장의 간격은 접근통행속도, 정류장 정차로 인한 손실시간, 승객의 통행거리가 증가함에 따라 길어지고, 통행수요와 배차간격이 늘어남에 따라 짧아진다. 본 연구에서는 수요의 분포가 균일하지 않을 경우 이용자비용과 운영자비용을 합한 총 비용을 최소화시키는 최적 정류장 간격을 도출하는 방법론을 제사하였다. 본 연구의 결과를 보다 일반적으로 확장하기 위해서는 재차 승객의 통행비용을 고려해야 하는데 이에 대해 개념적 예시를 통해 결과의 변화를 논의하였다. 이때의 정류장 위치변화를 살펴본 결과 재차 승객이 많은 구간의 정류장 간격이 다소 넓어지고, 재차 승객이 적은 구간의 정류장 간격이 다소 짧아지는 것을 확인할 수 있었고, 재차 승객이 증가하는 구간보다 재차 승객이 감소하는 구간에 정류장이 보다 많이 배치되는 것을 확인하였다. 본 연구는 동적 프로그래밍을 통해 정류장 위치를 결정하는 복잡한 방법 대신 수요분포의 면적을 균등하게 분할하여 각 정류장의 위치를 결정하는 간단한 방법론을 제시하여 실용적으로 활용될 수 있을 것으로 판단된다. 본 연구를 일반적으로 해석할 경우 모든 간격 설정 문제에 적용될 수 있다. 도로의 간격, 노선의 간격 등의 모든 시설물의 간격을 결정하는 문제에서 적용될 수 있으며, 간격변수를 공간에서 시간으로 변경하게 되면 배차간격을 결정하는 문제에도 바로 적용될 수 있는 확장성을 갖는다.

• 한국치위생학회지
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• 제8권2호
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• pp.53-66
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• 2008

There was to purpose of this study improves analyzing cause that prosthesis brings bite engaging that is inaccurate in patient's mouth, when supposed that all conducts that do in operatory and dental laboratory are perfect. Impression did check bite by alginate impression material and polymerization style silicon impression material that use usually in presence at a sickbed Irreversibility, hydrocolloid, alginate impression material washed in flowing water and poured anhydrite after wait about 8 minutes so that region that charge interest after impression check bite may become undoing. And hydrophile property addition polymerization style impression material poured anhydrite after blow 30 considering impression material dwell time and H2 gas occurrence time (5~15 minute) after have washed in flowing water. I got each 7 models, result that manufactures total 28 and measures by third dimension measuring instrument (Meteo, Korea) following sequence curing in tray holder and floor 1, By Alginate impression when is hardened in tray holder and when is hardened in the floor after do check bite, SPH 4, SPH5 all as there is synonymy appeared(P<0.05). By in case do not use average 0.1741 in case use tray holder in 0.0447 SPH5s in case do not use average 0.2838 pastas in case use tray holder in SPH4 0.0309, When did not use both SPH4 and SPH5 tray holder, when used tray holder, 1 appeared more greatly. 2. By amity sex addition polymerization style silicon impression when is hardened in tray holder after do check bite and when is hardened in the floor SPH 4, a11 of the SPH5s very big synonymy be(P>0.05). And in case use tray holder in 0.000657 pasta SPH5s in case do not use average 0.000129 pastas in case use tray holder in SPH4 average 0.000114 pastas, by in case do not use 0.000757, I appeared more greatly when used tray when did not use both SPH4 and SPH5 tray holder, but 1 appeared is not level to keep in mind(Table 8~9). 3 SPH4 was looked very big mindfulness in model that manufacture doing impression check bite by Alginate and model that do impression check bite by amity sex accessory penalty silicon without using tray holder(P< 0.001). I use tray holder and SPH4 did not appear synonymy in model that manufacture doing impression check bite by Alginate and model that do impression check bite by amity sex accessory penalty silicon(P>0.05). Study finding of above when see synthesis Alginate certainly tray holder use must and I could know that hardening method does not exert big influence on volume stability if remove impression sieve of excess because amity sex accessory penalty silicon passes over tray, Also, Alginate impression material previewed can get heading a conspiracy style that volume stability of accessory penalty silicon impression material degree is if use tray holder.

• 한국콘텐츠학회논문지
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• 제17권10호
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• pp.300-306
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• 2017

본 연구는 상업용 글라스아이오노머 시멘트(GIC) 분말에 기능화 다중벽 탄소나노튜브(MWCNT)를 첨가하여 항균효과와 기계적 성질을 개선하고자 하였다. MWCNT를 기존의 GIC 분말에 0.125, 0.25, 0.5와 1.0 wt%를 첨가하여 조성하였다. 비커스 경도(VHN)는 (Ø$10mm{\times}2mm$) 각각 4개의 시편을 제작하여 증류수에 1일, 7일, 14일 보관 후 200 N 하중에서 20초 유지시간으로 경도를 측정하였으며 항균효과는 S. mutans와 S. aureus균주를 아가 디스크 확산법으로 억제대를 측정하여 평가하였다. 실험 결과 비커스 경도는 MWCNT를 첨가한 실험군에서 높은값을 보였으며 MWCNT를 첨가한 모든 실험군에서 침전시간이 증가할수록 유의하게 높은 경도값을 보였다(p<0.05). 항균실험은 S. mutans균에서 다소 높은 항균효과를 보였으나 통계적으로 유의한 차이는 나타나지 않았으며, S. aureus균은 MWCNT를 0.25 wt%첨가한 군에서 통계적으로 유의한 차이점을 보였다(p<0.05). 이상의 결과로 MWCNT를 첨가한 GIC는 항균효과와 기계적 성질에 효과가 있음을 입증하였다. 추후 MWCNT의 효율적인 기능화 처리에 대한 연구가 필요할 것으로 사료된다.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.1
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• pp.27-31
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• 2006

GNSS Services and Applications are today in permanent evolution in all the market sectors. This evolution comprises: ${\bullet}$ New constellations and systems, being GALILEO probably the most relevant example, but not the only one, as other regions of the world also dwell into developing their own elements (e.g. the Chinese Beidou system). ${\bullet}$ Modernisation of existing systems, as is the case of GPS and GLONASS ${\bullet}$ New Augmentation services, WAAS, EGNOS, MSAS, GRAS, GAGAN, and many initiatives from other regions of the world ${\bullet}$ Safety of Life services based on the provision of integrity and reliability of the navigation solutions through SBAS and GBAS systems, for aeronautical or maritime applications ${\bullet}$ New Professional applications, based on the unprecedented accuracies and integrity of the positioning and timing solutions of the new navigation systems with examples in science (geodesy, geophysics), Civil engineering (surveying, construction works), Transportation (fleet management, road tolling) and many others. ${\bullet}$ New Mass-market applications based on cheap and simple GNSS receivers providing accurate (meterlevel) solutions for daily personal navigation and information needs. Being on top of this evolving market requires an active participation on the key elements that drive the GNSS development. Early access to the new GNSS signals and services and appropriate testing facilities are critical to be able to reach a good market position in time before the next evolution, and this is usually accessible only to the large system developers as the US, Europe or Japan. Jumping into this league of GNSS developers requires a large investment and a significant development of technology, which may not be at range for all regions of the world. Bearing in mind this situation, MAGIC appears as a concept initiated by a small region within Europe with the purpose of fostering and supporting the development of advanced applications for the new services that can be enabled by the advent of SBAS systems and GALILEO. MAGIC is a low cost platform based on the application of technology developed within the EGNOS project (the SBAS system in Europe), which encompasses the capacity of providing real time EGNOS and, in the near future, GALILEO-like integrity services. MAGIC is designed to be a testing platform for safety of life and liability critical applications, as well as a provider of operational services for the transport or professional sectors in its region of application. This paper will present in detail the MAGIC concept, the status of development of the system within the Madrid region in Spain, the results of the first on-field demonstrations and the immediate plans for deployment and expansion into a complete SBAS+GALILEO regional augmentation system.

• 한국ITS학회 논문지
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• 제10권1호
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• pp.27-41
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• 2011

본 논문은 도시부 간선도로의 트램을 위한 고정식 우선신호 전략으로 트램의 연동모형 MAXBAND MILP-Tram을 제시하였다. MAXBAND MILP-Tram은 전통적인 간선도로 연동모형인 MAXBAND를 기반으로 하고 있으며, 중앙트램 전용 차로의 트램과 일반차로의 승용차 모두를 위한 이중화된 연동폭을 산정할 수 있다. 본 모형은 일반차량 대비 낮은 속도와 정류장 정차시간이 포함되는 통행시간을 가지는 트램 통행특성을 고려하여 연동폭을 산정할 수 있다. 중앙트램전용차로에서는 현시순서에 따라 트램의 녹색시간이 크기를 달리하게 되며, 이를 제약조건으로 표현하였다. 미시적 시뮬레이션 효과분석을 수행하여 트램 연동모형의 효과분석을 위한 트램과 교차로의 제어지체와 사람당 제어지체 변화를 확인하였다. MAXBAND MILP-Tram으로 산출된 신호시간을 VISSIM에 적용한 결과 MAXBAND MILP-2 대비 트램의 차량당 평균 제어지체는 57%가 감소된 결과를 나타내었으나, 교차로 평균 제어지체의 경우 일반차량의 연동폭이 감소함에 따라 MILP-Tram은 MILP-2 대비 18% 증가된 결과를 나타내었다. 또한 일반차량의 교통량 변화를 이용한 민감도 분석에서는과포화 상태에 근접함에 따라 MAXBAND MILP-Tram과 같이 �낵째� 현시순서만을 변경시키는 우선신호 기법은 사람당 지체를 감소시킬 수 있는 유용한 수단임을 확인하였다.

• 대한치과보철학회지
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• 제38권5호
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• pp.595-605
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• 2000

Dental ceramics have good aesthetics, biocompatibility, low thermal conductivity, abrasion resistance, and color stability. However poor resistance to fracture and shrinkage during firing process have been limiting factors in their use, particularly in multiunit ceramic restorations. A new method for making all-ceramic crowns that have high strength and low processing shrinkage has been developed and is referred to as the Vita In-Ceram method. This study was performed to investigate the effect of $CeO_2$ addition in borosilicate glasses on the strength of alumina-glass composites. Porous alumina compacts were prepared by slip casting and sintered at $1,100^{\circ}C$ for 2 hours. Dense composites were made by infiltration of molten glass into partially sintered alumina at $1,140^{\circ}C$ for 4 hours. Specimens were polished sequentially from #800 to #2000 diamond disk. and the final surface finishing on the tensile side was received an additional polishing sequence through $1{\mu}m$ diamond paste. Biaxial flexure test was conducted by using ball-on-three-ball method at a crosshead speed of 0.5mm/min. To examine the microstructural aspect of crack propagation in the alumina-glass composites, Vickers-produced indentation crack was made on the tensile surface at a load of 98.0 N and dwell time of 15 sec, and the radial crack patterns were examined by an optical microscope and a scanning electron microscope. The results obtained were summarized as follows; 1. The porosity rates of partially sintered alumina decreased with the rising of firing temperature. 2. The maximum biaxial flexure strength of 423.5MPa in alumina-glass composites was obtained with an addition of 3 mol% $CeO_2$ in glass composition and strength values showed the aspect of decrease with the increase of $CeO_2$ content. 3 The biaxial flexure strength values of alumina-glass composites were decreased with rising the firing temperature. 4. Observation of the fracture surfaces of alumina-glass composites indicated that the enhancement of strength in alumina-glass composites was due to the frictional or geometrical inter-locking of rough fracture surfaces and ligamentary bridging by intact islands of materials left behind the fracture front.

• 한국환경복원기술학회지
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• 제2권1호
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• pp.48-57
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• 1999

This study was aimed to establish biotop unit of the mixed rural city for the method and process of the biotop mapping system. Survey site was Maejuri of Seunghwan(158ha), Gisanri of Mokchon(132ha) and Namkwanri, Pungsemeon(214ha). So the main process was divided by 4 schemes such as Biosphere, Geosphere, Antrosphere and Evaluation. Also the GIS(geographic information system) was used to make the database of the biotop and biotop complex, analyze the cross-combinations and analyze the characters of the biotop. Biotop mapping system had 5 steps which were proceeded with research goals, constructing the spatial database and attribute database, classifying the 3 types of biotop such as tree/shrub biotop, grass biotop and wetland biotop, cross-analyzing 3 biotop types with land use, habitat characters, relief characters and danger/disturbance elements and evaluating the 3 types of biotop. The results of applicating the biotop mapping system on the research site as followings : The distributions of the land uses in Maejuri, Seunghwan eup in Chonan city were recorded by forest(29.8%), orchard(14.1%) and landscaping around building site(9.0%). Gisanri, Mokchonmeon were composed of forest(64.5%), farm(12.8%) and Namkwanri, Pungsemeon were concentrated rice field(39.6%), dwell district(22.4%). The Tree/Shrub biotop type was reclassed by the forest type, natural and artificial decidous type with natural coniferous. The Grass biotop type was reclassed by the wild grassland type, garden type and peddy field with wild grassland. The distributions of the wet land were pointed high at the wet land type with reed marsh and edge vegetation around wet land in reservoir and river. The evaluation of the mapped bitopes was completed to the following aspect, "amenity" and "environmental education". A high value of 7.13%(1 class) was shown Maejuri, Seunghwan eup. The regions which were studied synthetically are divided to three parts ; the area where have nature and art mixed(Seunghwan), the area which is more artificial because people inhabit there for a long time(Pungsemeon) and the area that ecological environment is threatened by development pressure(Mokchonmeon). Therefore, ecological restoration plan which depends on specific property of the regions should be established. Also the interdisplinary researches were needed to develop the BMS(Biotop Mapping System) in Korea because of the differences with Germany, England's ecological habitat conditions.