• Korean Journal of Clinical Laboratory Science
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• v.53 no.1
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• pp.11-18
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• 2021

Respiratory viruses (RVs) cause infections in hospital environments through direct contact with infected visitors. In infection control, it causes major problems of acquired infections in hospitals by respiratory viruses. The surveillance data derived from clinical laboratories are often used to properly allocate medical resources to hospitals and communities for treatment, consumables, and diagnostic product purchases in the institutions and public health sectors that provide health care. An early diagnosis is essential in infection with respiratory viruses, and methods that can be used in diagnostic methods using respiratory samples include virus culture, molecular diagnosis, and analysis. A microchip provides a new strategy for developing a more diverse and powerful technology called point-of-care testing. The importance of the respiratory system should be applied strictly to the infection control guidelines to ensure the occupational health and safety of health care workers. Evidence of clinical efficacy, including this study, is challenging the long-standing paradigm for infection propagation. Additional assistance will be needed for frequent tests to detect respiratory viruses in inpatients who have begun to show new respiratory symptoms indicating infections requiring efforts to control the infection.

• Korean journal of applied entomology
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• v.59 no.2
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• pp.83-91
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• 2020

We assessed efficacy of spraying pesticides from an unmanned helicopter to control two insect species, Monochamus alternatus and M. saltuarius, which are vectors of pine wood nematodes. Control efficacy of thiacloprid FL (33×), acetamiprid ME (33×), and flupyradifurone SL (33×) was determined by placing caged insects in the canopy of pine trees (Pinus sp). Water-sensitive paper was used to record the spray pattern of pesticide droplets and the degree of coverage; furthermore, we investigated peripheral scattering due to spraying. The three pesticides showed > 96% control efficacy against the targeted vectors, and pesticide droplet spray patterns were similar. Peripheral scattering was observed up to 20 m in front and 10 m to the left, right, and behind the targeted area. The coverage index of all the directions at 5 and 10 m distance was 6-7 and 2, respectively.

• Journal of Bio-Environment Control
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• v.20 no.4
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• pp.394-398
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• 2011

The effect of two-fluid fogging system on the control of Bemisia tabaci in tomato cultivation was evaluated in a greenhouse. The number of Bemisia tabaci was decreased by 87% from the fog treatment for 7 days. During the fog treatment, the mean daily temperature was decreased by $2^{\circ}C$ and the mean daily relative humidity was increased by 3~4% as compared to the non-treatment. The reduction of Bemisia tabaci in the treatment might not be resulted from the differences in temperature and humidity in the greenhouse. The sound coming from the two-fluid fogging system did not affect when it was operated without water inside. Therefore it was concluded that water droplets coming out the nozzle reduced the growth and the movement of whiteflies because the suspension of tiny water droplets were attached on the skin of whiteflies.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.4
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• pp.1092-1096
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• 2003

This study was carried out to investigate the clinical effects of Tongbiyeum(TBY) ₂on hyperlipidemia. The hyperlipidemia of rats was induced by feeding high cholesterol diet for 4 weeks. We checked serum lipids and body weight weekly for 4 weeks. After the termination of treatment, we measured liver weight and observed histopathological change. We compared result of TBY group with control group. Thereafter, we made a study of 37 hyperlipidemic patients who visited us, the oriental medical center Daejeon and cheongju of Daejeon University, from November, 2001 to April, 2002. After administering TBY for 1 month, we followed up their total cholesterol, triglyceride and HDL-Cholesterol levels. The results were as follows; TBY treatment inhibited the liver weight gain induced by high cholesterol diet as compared with control group. TBY treatment inhibited lipid droplet accumulation and apoptotic change in liver as compared with control group. TBY treatment significantly inhibited the increasing of serum triglyceride and total cholesterol levels induced by high cholesterol diet as compared with control group but not affect HDL-cholesterol level. After administering TBY, the serum total cholesterol, triglyceride and LDL-cholesterol levels of hyperlipidemic patients were decreased significantly. After administering TBY, the serum HDL-Cholesterol level of hyperlipidemic patients had no significant changes. According to above mentioned results, we can infer that TBY has hypolipidemic effect to be applicable to artheriosclerosis.

• BMB Reports
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• v.57 no.5
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• pp.232-237
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• 2024

This study investigated how adipose tissue-derived mesenchymal stem cells (AT-MSCs) respond to chondrogenic induction using droplet-based single-cell RNA sequencing (scRNA-seq). We analyzed 37,219 high-quality transcripts from control cells and cells induced for 1 week (1W) and 2 weeks (2W). Four distinct cell clusters (0-3), undetectable by bulk analysis, exhibited varying proportions. Cluster 1 dominated in control and 1W cells, whereas clusters (3, 2, and 0) exclusively dominated in control, 1W, and 2W cells, respectively. Furthermore, heterogeneous chondrogenic markers expression within clusters emerged. Gene ontology (GO) enrichment analysis of differentially expressed genes unveiled cluster-specific variations in key biological processes (BP): (1) Cluster 1 exhibited up-regulation of GO-BP terms related to ribosome biogenesis and translational control, crucial for maintaining stem cell properties and homeostasis; (2) Additionally, cluster 1 showed up-regulation of GO-BP terms associated with mitochondrial oxidative metabolism; (3) Cluster 3 displayed up-regulation of GO-BP terms related to cell proliferation; (4) Clusters 0 and 2 demonstrated similar up-regulation of GO-BP terms linked to collagen fibril organization and supramolecular fiber organization. However, only cluster 0 showed a significant decrease in GO-BP terms related to ribosome production, implying a potential correlation between ribosome regulation and the differentiation stages of AT-MSCs. Overall, our findings highlight heterogeneous cell clusters with varying balances between proliferation and differentiation before, and after, chondrogenic stimulation. This provides enhanced insights into the single-cell dynamics of AT-MSCs during chondrogenic differentiation.

• Journal of Drive and Control
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• v.21 no.2
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• pp.53-64
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• 2024

Global population growth has resulted in an increased demand for food production. Simultaneously, aging rural communities have led to a decrease in the workforce, thereby increasing the demand for automation in agriculture. Drones are particularly useful for unmanned pest control fields. However, the current method of uniform spraying leads to environmental damage due to overuse of pesticides and drift by wind. To address this issue, it is necessary to enhance spraying performance through precise performance evaluation. Therefore, as a foundational study aimed at optimizing drone-based pest control technologies, this research evaluated water-sensitive paper (WSP) via density map estimation using convolutional neural networks (CNN) with a encoder-decoder structure. To achieve more accurate estimation, this study implemented multi-task learning, incorporating an additional classifier for image segmentation alongside the density map estimation classifier. The proposed model in this study resulted in a R-squared (R²) of 0.976 for coverage area in the evaluation data set, demonstrating satisfactory performance in evaluating WSP at various density levels. Further research is needed to improve the accuracy of spray result estimations and develop a real-time assessment technology in the field.

• Proceedings of the Korean Vacuum Society Conference
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• 2015.08a
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• pp.126.1-126.1
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• 2015

A quantitative relationship between Leidenfrost point and surface characteristics such as surface material and roughness is investigated. Based on the relationship, we have fabricated the surfaces with their Leidenfrost points (LFP) tuned by controlling surface coating and structures. As discovered by Leidenfrost, liquids placed on a hot plate levitate on the gas phase-air gap formed by the vaporization of liquids. This phenomenon is called 'Leidenfrost effect'. A change of LFP has attracted many researchers for several years but the ability to tune LFP is still a remaining issue. Many of previous work has progressed for various conditions so the systematic approach and analysis are needed to clearly correlate the LFP and the surface conditions. In this report, we investigate a relation of surface energy and LFP using various coating materials such as Octadecyltrichlorosilane (OTS) and 1H, 1H, 2H, 2H-Perfluorooctyltrichlorosilane (FOTS). Also, we analyze how surface roughness affects LFP via surface micro structuring with ICP-RIE fabrication process. The improved understanding can have potential applications such as the control of liquid droplet behavior at elevated temperatures for efficient cooling system.

• Clinical and Experimental Pediatrics
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• v.52 no.8
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• pp.862-868
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• 2009

Since its identification in April 2009, a swine-origin H1N1 influenza A virus (S-OIV) which is a reassortment of gene segments from both North American triple-reassortant and Eurasian swine influenza has been widely spread among humans in unexpected rapidity. To date, each gene segment of the 2009 influenza A (H1N1) outbreak viruses have shown high (99.9%) neucleotide sequence identity. As of July 6, 94,512 people have been infected in 122 countries, of whom 429 have died with an overall case-fatality rate of <0.5%. Most confirmed cases of S-OIV infection have been characterized by self-limited, uncomplicated febrile respiratory illness and 38% of cases have also included vomiting or diarrhea. Standard plus droplet precautions should be adhered to at all times. Tests on S-OIV have indicated that current new H1N1 viruses are sensitive to neuraminidase inhibitors (oseltamivir). However, current less virulent S-OIV may evolve into a pathogenic strain or acquire antiviral resistance, potentially with more severe clinical consequences. Efforts to control these outbreaks would be based on our understanding of novel S-OIV and previous influenza pandemics.

• Journal of the Korean Applied Science and Technology
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• v.23 no.1
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• pp.1-11
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• 2006

The W/O emulsion was formed by mixing hydrophobic nonion surfactants of span 80 and tween 60 with kerosine, and by adding sodium silicate aqueous solution. Precipitating the W/O emulsion by sodium bicarbonate resulted in spherical silica particles. Shape and size distribution of silica particles were observed. The particles were spherical and they have narrow size distribution. Particle sizes were 9.29, 7.39 and $5.73\;{\mu}m$ at homogenizer speed of 2500, 3000, and 3500 rpm, respectively. The particle size was decreased by increasing agitation speed due to the formation of emulsion droplet. At fixed agitation speed, absorbed paraffin oil weight were measured and the $SiO_2/Na_2O$ mole ratio effects on particle size were investigated. Particle size was decreased by increasing the mole ratio of $SiO_2/Na_2O$.

• Journal of the Korean Society for Marine Environment & Energy
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• v.1 no.2
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• pp.18-26
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• 1998

The major interest of this paper is how the spilled oil over the sea is dispersed into water column especially under the shear and turbulence such as breaking wave. Two hydraulic experiments were conducted to investigate the oil stick break-up characteristics into small and large droplets under the variation of velocity shear and breaking waves. From the experiments in the shear generator and the wave flume, small droplets which have diameters of tens to hundreds of micrometers were uniformly distributed throughout the whole control volume as time goes by. In addition, it can be seen that the weathered spilled oil has a different break-up mechanism from fresh spilled oil.