• Title/Summary/Keyword: Down-aging

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Physicochemical Properties of Chestnut Starch (밤 전분의 이화학적 특성)

  • Park, In-Soon;Kim, Sung-Kon;Kim, Chun-Soo
    • Applied Biological Chemistry
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    • v.25 no.4
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    • pp.218-223
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    • 1982
  • Physicochemical properties and aging of chestnut, Castanea cretana(Eungi), starch were investigated. The starch granules were irregular oval shape with the ratio of short and long axis of 1 : 1.4 and the size of $2.9-21.4{\mu}$ (average $10\;{\mu})$). The starch showed a typical B-type X-type diffraction pattern. Amylose content and water binding capacity were 22.7% and 81.5%, respectively. The optical transmittance of 0.1% starch suspension increased rapidly from $55^{\circ}C$. The swelling power of the starch repidly increased betwen $55^{\circ}C$ and $60^{\circ}C$, and its increase slowed down thereafter. Amylograms of starch at 5% and 6% concentrations indicated that the starch was stable against heat and shear force. The viscosity at 6% concentration was over twice higher than that at lower concentration. The time constant(reciprocal of rate constant) for 45% starch gel stored at $21^{\circ}C$ was 1.68 days.

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The Characteristics of Traffic Accidents and Reduction Methods by Elderly Drivers to Prepare for the Aging Society -Focused on Jeju- (고령사회를 대비한 노인운전자 교통사고 특성 및 저감방안 -제주지역을 중심으로-)

  • Kim, Kyung-Bum
    • The Journal of the Korea Contents Association
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    • v.14 no.7
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    • pp.151-160
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    • 2014
  • The purpose of this study is to deduce improvement plan through analysis of the type and characteristics of traffic accidents caused by elderly drivers, and to establish the traffic safety policies for the elderly drivers. The analyzed result of road traffic accident situation are as follows. Firstly, Traffic accidents caused by elderly drivers were frequent on local roads of poor traffic safety facilities such as lighting. Secondly, The most frequent time zone of Traffic accidents caused by elderly drivers was 18:00 to 20:00, this time zone was mainly darkened. Thirdly, Traffic accidents are often caused by lack of attention occurred by no implementation of safe driving. Institutional Improvement of cosideration for elderly drivers and Traffic Safety Facilities maintenance considering regional particularities is needed for reducing traffic accidents and the safety of our society. Their driving skills of elderly drivers should test themselves constantly, and elderly drivers must hold down driving yourself using the alternative transportation.

The analysis about the course of studying renal stones -On the basis of incurable and relapse renal stones' differentiation of symptoms and signs- (요로결석(尿路結石) 연구동향(硏究動向)에 대한 분석(分析) - 난치(難治)와 재발(再發)의 판증(辦證)을 중심으로 -)

  • Lee, Jung-Won;Kim, Chueng-Jung;Cho, Chung-Sik
    • Journal of Haehwa Medicine
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    • v.14 no.2
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    • pp.143-151
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    • 2005
  • Gobjectives and Methods to investigate into the course of incurable and relapse renal stones' differentiation of symptoms and signs and to effectively improve treatment of incurable and relapse renal stones through Oriental Medicine. To search for the papers about treatment of incurable and relapse renal stones from 1994 till 2004, and re-search papers about treatment for indicated differentiation of disease. Result and conclusions : 1. It is the kidney vacuity additionally the deficiency of qi(氣) in middle-burner that the incurable and relapse renal stones' differentiation of disease. 2. The cause is taking an overdose of attacking renal stones to eliminate dampness and heat medicine, aging, chrome disease. a sex act excess, insufficiency of congenital qi(氣), insufficient exercise, wrong treatment and stress. 3. Herb medicines are constituted supplementing kidney drugs for inhibition of renal stone's creation, drugs to diuresis and dissolve calculi, and drugs 10 exclude stasis blood(瘀血) on account of renal stones. 4. Anti-renal stone measures me sufficiently drinking water, not eating greasy food. taking medicine for supplementing kidney, diuresis and dissolve calculi by periods, and drinking substitute water to boll down medical herb as Lysimachiae Herba (金錢草) Polygoni Avicularis Herba(篇蓄).

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Fundamental Frequencies in Korean Elderly Speakers (한국 정상 노인 음성의 기본주파수)

  • Kim, Sun-Hai;Ko, Do-Heung
    • Speech Sciences
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    • v.15 no.3
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    • pp.95-102
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    • 2008
  • Multiple physical changes of the larynx and its components occur with age. Vocal pitch, commonly expressed through measures of fundamental frequency (Fo) relate to physical conditions of the larynx. Available data is lacking for the senescent voice, and should be applied to the of changes of elderly speakers' Fo characteristics. The purpose of this study was to investigate the Fo of normal elderly speaker's voice. A total of 406 normal elderly speakers (207 males and 199 females) participated in this experiment. Age ranged from 60 years to 89 years. The subjects were asked to produce sustained corner vowels (/a/ /i/ /u/) three times each and the data were analyzed using the MDVP of CSL. According to the results of this study, the mean Fo from the ages of 60's to 80's shows 143.95Hz(SD 13.94) for men and 185.42Hz (SD 15.29) for women. For men, a significant change is found as a function of age in the Fo (F=16.181, p<.05). A post-hoc Scheffe test revealed significant differences between the Fo data of subjects aged 60's and 70's, 60's and 80's. For women, a significant change is found as a function of age in the Fo (F=49.013, p<.05). A post-hoc $Scheff'{e}$ test revealed significant differences between the Fo data of subjects in their 60's and 70's, 70's and 80's, 60's and 80's. The Fo of men goes up from their 60's to 80's gradually, whereas the Fo of women goes down gradually until their 70's, and after their 70's it again increases. It has been known that diminishing estrogen levels in women in old age may be a factor in lowering Fo, whereas diminishing testosterone levels in men may contribute to a rising Fo. This result may be used as some meaningful guideline and lead the basic data to differentiate between normal aged voice and aged voice disorders.

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Family Planning and Maternal-Child Health Services that Disciplined Itself in Primary Health Care Post from 1980 to 2009 (보건진료소 가족계획 및 모자보건사업(1980년~2009년))

  • Son, Gye-Soon
    • Journal of Korean Academy of Rural Health Nursing
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    • v.3 no.2
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    • pp.104-115
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    • 2008
  • Purpose: A study of the family planning and Maternal-Child Health Services that disciplined itself in primary health care post form 1980 to 2009. Method: Investigation studies family planning in primary health care post and a change process of a Maternal-Child Health Services into case by case until 2009 from 1980. Results: Our country family planning business began at economic development dimensions in order to solve a poverty issue. This business goal were childbirth decrease of pregnancy possibility couple aged 19~49 and improve to mother and child health. For this goal, all kinds of health education included sex education and contraception education, contraception service, comprehensive maternal and child health service that management of front and back of childbirth etc. are provided. According to fail down a birthrate from 6.0(1962) to 1.25(2009), the nation reached to a dilemma called childbirth encouragement policy. Conclusions: Decrease of labor supply by low birthrate, decrease numerical an employed person by aging was brought a labor shortage and decrease of productivity of labor of industrial manpower. Deterioration phenomenon of financial income and expenditure by consumption and investment contraction caused decrease of slowdown of economic growth and potential growth rate, and a social cost burden is increased by deterioration financial old man support burden increase by this and pensions and health insurance, a sharp increase of social welfare cost etc. Now, in order to solve a low birth issue, the government establishes a whole nation forwarding system and establishes basic plan social low birth and advanced age, and to prepare for childbirth fault factors removal and advanced age society shall endeavor.

Development of Easily Chewable and Swallowable Hot Pepper Paste Stir-Fried Pork and Seasoned Spinach for Elderly (고추장 제육볶음 및 시금치나물 저작·연하 용이 노인식 개발)

  • Kim, Soojeong;Joo, Nami
    • The Korean Journal of Food And Nutrition
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    • v.29 no.4
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    • pp.480-485
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    • 2016
  • This study was conducted to develop food for the elderly, which is easier to chew and swallow, using gelification. Various foods for the elderly with chewing and swallowing difficulties were used for sensory assessment. The sensory panel consisted of 10 dieticians (10 women) working in nursing care facilities. The sensory optimal composite recipes were determined by the central composite design (CCD). The optimum formulation of hot pepper paste stir fried pork calculated by the numerical and graphical method was 1.48 g of sugar and 18.97 g of hot pepper paste. The optimum formulation of seasoned spinach was 8.0 g of sesame oil and 5.41 g of soy sauce. Moisture content, hardness, and adhesiveness of hot pepper paste stir fried pork was 76.49%, 2.50, and -1.20, respectively. Moisture content, hardness, and adhesiveness of seasoned spinach was 83.48%, 2.27, and -1.17, respectively. This study provides the basic materials for the development of easily chewable and swallowable foods for the elderly, which can reduce the risk of food going down the wrong pipe, and the preference can be improved by eating solid food instead of porridge or liquid food. The development of food for the elderly, which takes the difficulties in chewing and swallowing among the elderly into consideration and reflects their preference and has sufficient amount of nutrients, is important to enable the elderly to enjoy their meals and it is one of the biggest challenges in Korea, as Korean society is aging rapidly.

Study on the public interest type of the senior's job programme, Efficiency measures in the market-type (노인일자리사업의 사회공헌형, 시장진입형 효율화 방안에 관한 연구)

  • Cho, Woo-Hong
    • Journal of the Korea Society of Computer and Information
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    • v.19 no.12
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    • pp.349-357
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    • 2014
  • Korea is going to the structure of low fertility and aging population, which is so difficult to find a precedent in the world. Furthermore, since population structure is changing to the upside down pyramid type, it acts as a factor that makes the production population matters worse. In this situation, senior's job programme has fixed those problems to a certain extent, but more effective support system should be provided in the respect of economic and social integration. Also efforts should be made for a view to a wide range of job creation and dissemination. Decent jobs can be created in the area of culture, welfare, health care, tourism, by utilizing skills and experience that senior had before they retired. In conclusion, this study provides a theoretical basis for an efficient measure of senior's job programme.

SIRT7 Exhibits Oncogenic Potential in Human Ovarian Cancer Cells

  • Wang, Hong-Ling;Lu, Ren-Quan;Xie, Su-Hong;Zheng, Hui;Wen, Xue-Mei;Gao, Xiang;Guo, Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.8
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    • pp.3573-3577
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    • 2015
  • Background: Sirtuin7 (SIRT7) is a type of nicotinamide adenine dinucleotide oxidized form (NAD+)-dependent deacetylase and the least understood member of the sirtuins family; it is implicated in various processes, such as aging, DNA damage repair and cell signaling transduction. There is some evidence that SIRT7 may function as a tumor trigger for human malignancy. Here, we aimed to explore the biological function of SIRT7 in ovarian carcinoma cells and its potential mechanism. Materials and Methods: Expression of SIRT7 in ovarian cancer cell lines was detected by western blotting. Transduced cell lines with SIRT7 knockdown or overexpression were constructed. Cell viability, cologenic, apoptosis-associated and motility assays were performed to elucidate the biological function of SIRT7 in ovarian cancer cells. Results: SIRT7 demonstrated a higher level in ovarian cancer cell lines compared with normal cells. On the one hand, down-regulation of SIRT7 significantly reduced ovarian cancer cell growth, repressed colony formation and increased cancer cell apoptosis; on the other hand, up-regulation promoted the migration of cancer cells. Additionally, repression of SIRT7 also induced change in apoptosis-related molecules and subunits of the NF-${\kappa}B$ family. Conclusions: In the present study, our data indicated that SIRT7 might play a role of oncogene in ovarian malignancy and be a potential therapeutic target.

Enhancement of Skin-Whitening and UV-Protective Effects of Centella asiatica L. Urban by Utrasonification Process (초음파 병행을 통한 병풀의 미백 및 자외선 차단 활성 증진 효과)

  • Ha, Ji-Hye;Kwon, Min-Chul;Kim, Seung-Seop;Jeong, Myoung-Hoon;Hwang, Baik;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.18 no.2
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    • pp.79-85
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    • 2010
  • Enhancement effect of ultrasonification process on UV-protection and skin-whitening activities using Centella asiatica L. Urban extract was investigated. Cytotoxicity of the extracts measured on human skin fibroblast cells, CCD-986sk, and then, ultrasonification associated extracts showed 5~9% lower cytotoxicity then normal crude extracts on 1.0 mg/$m{\ell}$ of highest sample concentration. The associated extrats showed highest inhibition activity of hyaluronidase on 1.0 mg/$m{\ell}$ of concentration as 54.2%. Also, the associated extract reduced expression of MMP-1 on UV-irradiated CCD-986sk cells down to 100.2% from 136.1%, and revealed high inhibitory potency on tyrosinase as 74.6% by adding 1.0 mg/$m{\ell}$ of concentration. Ultrasonification associated extract showed strong inhibition effect of melanin production on Clone M-3 cells as 84.2% by adding 1.0 mg/$m{\ell}$ of concentration. From the preliminary observations, we considered that the extracts from C. asiatica could be potent natural materials for skin-whitening and anti-aging agent, and could enhance the activities by ultrasonification process.

A Threshold-voltage Sensing Circuit using Single-ended SAR ADC for AMOLED Pixel (단일 입력 SAR ADC를 이용한 AMOLED 픽셀 문턱 전압 감지 회로)

  • Son, Jisu;Jang, Young-Chan
    • Journal of IKEEE
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    • v.24 no.3
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    • pp.719-726
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    • 2020
  • A threshold-voltage sensing circuit is proposed to compensate for pixel aging in active matrix organic light-emitting diodes. The proposed threshold-voltage sensing circuit consists of sample-hold (S/H) circuits and a single-ended successive approximation register (SAR) analog-to-digital converter (ADC) with a resolution of 10 bits. To remove a scale down converter of each S/H circuit and a voltage gain amplifier with a signl-to-differentail converter, the middle reference voltage calibration and input range calibration for the single-ended SAR ADC are performed in the capacitor digital-to-analog converter and reference driver. The proposed threshold-voltage sensing circuit is designed by using a 180-nm CMOS process with a supply voltage of 1.8 V. The ENOB and power consimption of the single-ended SAR ADC are 9.425 bit and 2.83 mW, respectively.