• International Journal of Highway Engineering
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• v.16 no.2
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• pp.19-24
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• 2014

PURPOSES : The study objective was to evaluate rheology and physical properties of SBS-modified warm-mix asphalt (WMA) binders in comparison with hot-mix asphalt (HMA) binders. METHODS : Four different SBS polymers were used to prepare polymer-modified asphalt (PMA) binders, and three different warm-mix additives (WAD) were used to prepare a total of 12 WMA PMA binders. The kinematic viscosity was measured at 115, $135^{\circ}C$. The PG was determined using DSR and BBR. The pass/fail (P/F) temperatures for high and low PG grading were evaluated for HMA PMA and WMA PMA binders. RESULTS : PG 76-22 binders could be prepared by modifying the base binder (PG 64-22) using 4.5 wt% of SBS. The kinematic viscosity (KV) of SBS PMA was increased by 3 times higher than that of base asphalt. The SBS PMA with WAD showed 10% lower KV than that of the normal SBS PMA at $115^{\circ}C$ The high P/F temperatures showed almost no difference between HMA PMA and WMA PMA binders. The high P/F temperature showed very high correlations with KV ($R^2$ > 0.97). The result of SBS modification caused increase of low P/F temperature by $2.7^{\circ}C$ on average. CONCLUSIONS : Since the PMA with WAD showed 10% lower KV than normal (HMA) PMA at $115^{\circ}C$, reducing PMA mixture temperature down to a WMA level was possible in this study. The higher KV binders showed the higher P/F temperature. There was almost no change in high P/F temperature due to the use of WAD. The SBS PMA, showing an increased low P/F temperature, might show somewhat poorer performance at low-temperature, even though the lower PG grade was staying at the same level, i.e., $-22^{\circ}C$.

• IMMUNE NETWORK
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• v.9 no.6
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• pp.255-264
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• 2009

Background: Chronic low grade inflammation is closely linked to type II diabetes, obesity, and atherosclerosis. Macrophages play a key role in the regulation of pro- or anti-inflammatory actions at the lesion sites of disease. Components of cordyceps militaris, cordycepin and adenosine, have been used for the modulation of inflammatory diseases. The effects of cordycepin in the modulation of macrophages have yet to be be elucidated. We investigated the effects of cordycepin and adenosine on the morphological changes of macrophages under the inflammatory condition of LPS and an anti-inflammatory condition involving high concentrations of adenosine. Methods: We confirmed the mRNA levels of the M1/M2 cytokine genes through RT-PCR and morphological change. Results: LPS-activated macrophages returned to their inactivated original shape, i.e., they looked like naive macrophages, through the treatment with high concentrations of cordycepin ($40{\mu}g/ml$). LPS and adenosine activated macrophages also returned to their original inactivated shapes after cordycepin treatment; however, at relatively higher levels of cordycepin than adenosine. This change did not occur with relatively low concentrations of cordycepin. Adenosine down-regulated the gene expression of M1 cytokines (IL-$1{\beta}$, TNF-${\alpha}$) and chemokines (CX3CR1, RANTES), such as cordycepin. Additionally, M2 cytokines (IL-10, IL-1ra, TGF-${\beta}$) were up-regulated by both cordycepin and adenosine. Conclusion: Based on these observations, both cordycepin and adenosine regulated the phenotypic switch on macrophages and suggested that cordycepin and adenosine may potentially be used as immunomodulatory agents in the treatment of inflammatory disease.

• Journal of Korean society of Dental Hygiene
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• v.16 no.4
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• pp.559-566
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• 2016

Objectives: This research has executed a new oral health promotion program among the elderly residents of a long-term care center, which purpose was to verify its effectiveness of oral health promotion through the improvement of their oral function. Methods: This study has selected the elderly over the age of 65, capable of communication, who use a long-term care center over the period of two months between July and September 2014. The subjects who remained until the final analysis numbered 50 excluding the dropouts during the program session (experimental: 33, control : 17). The oral stretching program was exercised two days a week, for total of two months. Each function was assessed by the standardized methods and measurement equipment. Also the sum of each function was converted into the oral health grade. Results: The oral function score of the experimental group also showed a statistically significant difference after the execution of the program, where the oral function score of experimental group increased $6.70{\pm}1.30$ from $4.95{\pm}0.89$ after the execution of the program (p<0.05), while the comparison group showed no valid statistical difference with the score result of $5.00{\pm}0.87$ down from $5.11{\pm}0.93$ after the execution of the program (p>0.05). Conclusions: Therefore if the oral health promotion program is reflected to the welfare policy in the future, it can be said that it contributes to the improved health status of the elderly who reside in the long-term care centers.

• Journal of The Korean Association of Information Education
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• v.9 no.3
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• pp.397-406
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• 2005

The goal of this research is to prove the efficiency of direct instruction by developing and applying an ICT teaching and learning course for physical education based on a direct instruction model. The curriculum for physical education requires the instructors example and feedback, and sometimes classes may be difficult to conduct due to reasons such as weather conditions. Also, in actual learning, the application of a learning model is inadequate. In these cases, using an ICT teaching and learning course, experts can show examples instead. The learners are provided with individual and suitable feedback and can make it practical for them by slowing down motions, sectional motion learning, and repetitive learning. It can also enhance the sharing of the instructors teaching and learning methods. Therefore, this research recomposed the commonly used direct teaching and learning methods in physical education in order to make it suitable for ICT utilized lessons. It was recomposed in a procedural model and each level was explicated, and in order to materialize this, an ICT teaching and learning course was developed. This was then applied to a Fifth grade class, and its learning effects were analyzed.

• Journal of the Korean earth science society
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• v.31 no.5
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• pp.500-520
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• 2010

The purposes of this case study were (1) to explore one experienced teacher's views on Earth Systems Education and (2) to describe and document the characteristics of the Earth Systems Education (ESE) curriculum provided by an exemplary middle school science teacher, Dr. J. All the essential pieces of evidence were collected from observations, interviews with the experienced teacher and his eighth grade students, informal conversations, document analysis, and field notes. The $NUD^*IST$ for MS Windows was used for an initial data reduction process and to narrow down the focus of an analysis. All transcriptions and written documents were reviewed carefully and repeatedly to find rich evidence through inductive and content analysis. The findings revealed that ESE provided a conceptual focus and theme for organizing his school curriculum. The curriculum offered opportunities for students to learn relevant local topics and to connect the classroom learning to the real world. The curriculum also played an important role in developing students' value and appreciation of Earth systems and concern for the local environment. His instructional strategies were very compatible with recommendations from a constructivist theory. His major teaching methodology and strategies were hands-on learning, authentic activities-based learning, cooperative learning, project-based learning (e.g., mini-projects), and science field trips. With respect to his views about benefits and difficulties associated with ESE, the most important benefit was that the curriculum provided authentic-based, hands-on activities and made connections between students and everyday life experiences. In addition, he believed that it was not difficult to teach using ESE. However, the lack of time devoted to field trips and a lack of suitable resource materials were obstacles to the implementation of the curriculum. Implications for science education and future research are suggested.

• Journal of agricultural medicine and community health
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• v.35 no.1
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• pp.46-55
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• 2010

Objectives: The aim of this study was to investigate the association of social support and quality of life of stroke patients. Methods: Stroke patients were interviewed by a direct contact survey among 160 person. A structured questionnaire was configured about demographic features, social support and health related quality of life(SF12). Data were collected from July to August 2009. Results: Among social support, satisfaction of dependable when you need help is the highest score(5.3) and console you when you are very upset is the lowest(4.0). Vitality among health related quality of life(HRQOL) is the higest score(55.9) and general health score is the the lowest(17.4). Physical component score(PCS) is lower than mental component. The results of multiple regression analysis about the factors affecting the PCS and MCS score, disability grade and feel better variable gave effect HRQOL. Conclusions: For improvement of HRQOL, among stroke patients, community social support, specially, when patients feeling generally down-in-the dumps, the rely on to help feel better was needed.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2007.05a
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• pp.83-125
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• 2007

Increasing energy costs have caused profitability problems for paper suppliers. Therefore unprofitable lines are being closed down. The actions aiming for improved profits are focused either on cost savings or on increasing the capacity of the remaining machines. The runnability of a paper machine and its total efficiency have a significant effect on energy consumption. Producing one ton of waste paper consumes at least as much energy as producing the same amount of sellable end product. New automation solutions enable significant cost-effective improvements to the total efficiency of a line without large investment projects. The measures focus on minimizing changes, interruptions, interruption recovery times and grade change times. Newest actuators, online quality measurements and wet end analysators create an improvement potential, which can be optimally implemented with the latest machine direction control solutions, based on model predictive control concepts. Equally, drying management is significant to the energy consumption. The newest control strategies optimize the use of various drying actuators for different situations; either by responding to changes as efficiently as possible or by using only the cheapest energy sources in stable situations. An even steam supply, which is vital for paper machines, is achieved with control for the power plant steam network. This makes possible to avoid the delays upon starting the paper machine and assure an even steam supply for the drying section and the actuators. This document describes means which have brought significant energy and raw material savings for paper machines. Metso Automation has provided efficiency improvement packages, which are usually based on optimized control of dry weight and drying in all running conditions. The solutions are based on performance analysis, on which the estimations for improvement potential and the necessary actions are based on. Typically benefits on an annual level have been from hundreds of thousands of euros to over one million euro. For example, variations in dry weight have been decreased more than 50%. The results are presented with a few examples. Additionally, the analysis models, adjustment solutions and the changes in running methods with which the results were achieved, are presented.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2503-2509
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• 2012

Considerable research has been conducted concerning galectin-9 and carcinomas, but little information is available about any relation with the hepatocellular carcinoma. In this study, we employed a small interfering RNA (siRNA) targeting galectin-9 to down-regulate the expression in HepG2 cells. As a result, after galectin-9 expression was reduced, cell aggregation was suppressed, while other behaviour such as the proliferation, adhesion and invasion to ECM, cell-endothelial adhesion and transendothelial invasion of the cells were markedly enhanced. When tumors of 200 patients with hepatocellular carcinoma were tested for galectin-9 expression by immunohistochemistry, binding levels demonstrated intimate correlations with the histopathologic grade, lymph node metastasis, vascular invasion and intrahepatic metastasis (P<0.05). Moreover, survival analysis indicated that patients with galectin-9 expression had much longer survival time than those with negative lesions, and the Log-rank test indicated that this difference was statistical significant (P<0.0001). The Cox proportional hazards model suggested that negative galectin-9 expression in hepatocellular carcinoma represented a significant risk factor for patient survival. We propose that galectin-9 might be a new prognostic factor with antimetastatic potential in patients with hepatocellular carcinoma.

• Journal of the Korean association of regional geographers
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• v.17 no.3
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• pp.348-356
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• 2011

Someday Mt. Baekdu could erupt by records of orogeny activity until today. This study is to predict influence area of lava flow and volcanic ash by simulation of volcanic eruption in the Mt. Baekdu. Simulation for eruption applied to supposing 7 grade of volcanic explosivity index, season from fall to spring. As a simulation results, lava flewed down into slope of China and volcanic ash diffused over the North Korea. Volcanic ash spreads to Ulneung area after nine hours. It was predicted that 61 cities and villages out of 27 administrative districts of Si-Gun were affected by volcanic ash in North Korea and an immense volume of volcanic ash was blown into farm lands, city areas and forests. This results expected to utilize information for disaster preparation of North Korea and joint research with South-North Korea and China.

• Journal of Korean Society of Rural Planning
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• v.21 no.3
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• pp.1-17
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• 2015

The value of rice-fields is being graded down in Korea because it has been estimated only from the size. The purpose of this study is to suggest a management plan in which the location and the size of valuable rice-fields for conservation are based on the results of appraising the worth of ecosystem services of rice-fields in Chungcheongnam-do region. The study is as follows; (1)selecting the indicators for evaluating the ecosystem services of rice-fields considering both general functions and special functions in the regional environment conditions, (2)classifying the grades of rice-fields in ecosystem service values, (3)suggesting the location and the size of valuable rice-fields for conservation, (4)calculating the total economic value of the ecosystem services of rice-fields. The results of this study are that the valuable rice-fields' locations for conservation are the grade I rice-fields and their total area is 100,000ha. Also, the value of the ecosystem services of rice-fields in Chungcheongnam-do region was equivalent to 32.8 trillion won. This amount is over 18 trillion won more than the amount obtained if the total rice-fields in Chungcheongnam-do region were to be transformed to other land-use types. The value of ecosystem services should be considered in the future when appraising the worth of rice-fields, and methods of estimating the ecosystem services of rice-fields need to be developed with a more objective and suitable index.