• Journal of the Korean Professional Engineers Association
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• v.20 no.3
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• pp.5-14
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• 1987

연속체의 해석에 있어서, 특별한 경우를 제외하고는, 구조물의 개략적인 거동을 파악해야 될 경우가 종종 있다. 이러한 요구에 부응하기 위해서 강체요소법(Rigid Element Method)이라 불리우는 새로운 해석법이 개발되었다. 강체요소법은 원래 평정연구실에서 벽식프리캐스트 철근콘크리트 구조물의 탄소성해석을 하기 위해서 개발된 해석법에 착안하여, 내수벽과 같은 연속체에 적용함으로서 시작된 수치해석법이다. 그 후 저자들은 도통쉘, 구형쉘 혹은 이들이 조합된 쉘구조물에 적용할 수 있도록 개발 확장하였다. 강체요소법의 기본개념은 연속체의 분해된 각 요소를 강체(rigid body)라고 가정하고, 각 요소들은 요소의 강성으로 치환된 가상스프링으로 서로 연결되어 있다고 가정하여, 이 가상스프링의 거동을 평가함으로서 전체구조물의 거동을 파악하는 해석법이다. 이때 요소의 주변에 취해진 스프링은 해석을 단순화하기 위해서 축력, 면내전단력 및 면외전단력만을 전달한다고 가정하고, 요소의 강체변위(자유도)는 요소내의 임의의 한 점에서 취하며, 이 점에서의 강체변위(rigid displacements)는 요소의 주변에 취해진 스프링을 통하여 다른 요소로 전달된다. 상기와 같은 강체요소법의 개념을 연속체의 탄성 및 탄소성해석에 적용하면, 해석적 개념이 단순할 뿐만 아니라 구조물 전체의 자유도수를 대폭 줄여 컴퓨터 계산시간을 절약할 수 있는 잇점이 있고, 거시적인 모델(macroscopic modeling)과 미시적인 모델 (microscopic modeling)의 중간적인 성격을 가지기 때문에 구조물의 파괴상황에 대해서도 그 개략을 파악할 수 있다. 본 논문에서는 강체요소법을 보다 일반화된 해석법으로 개발, 확장하기 위해서 종전에 단층스프링시스템(single-layer spring system)으로 해석이 어려웠던 문제점들을 보완한 복층프링시스템(double-layer spring system)을 사용함으로서 휨, 비틀림의 효과를 파악할 수 있는 이론적 개념을 적용한 새로운 구요소, 원통요소 및 평면요소를 개발하고, 이러한 강체요소들의 적합매트릭스의 유도 및 해석저긴 방법을 정식화하였다. 또 휨, 비틀림 및 전단력의 효과를 고려한 사각형원통요소 및 능형원 통요소를 이용하여 원통쉘의 탄성 및 탄소성해석할 수 있는 프로그램을 개발하고, 이 프로그램으로 캔틸레버로된 연속형철근콘크리트 원통쉘의 탄성 및 탄소성해석에 적용하여 구조물의 거동에 관한 수치해석의 결과, 즉 내력의 분포, 균열의 진전, 파괴의 상황 및 변형의 상태 등을 파악해 보았다.

• Journal of radiological science and technology
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• v.22 no.2
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• pp.17-21
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• 1999

There were four types of stomach contour included eutonic, hypotonic, steerhorn, and cascade. The aim of this study is to clarify relationship between incidence of stomach cancer and contour variation of the stomach. Double-contrast upper gastrointestinal study was performed in 1,546 patients, who had dyspepsia or other gastrointestinal tract symptoms. The radiographs were classified into the four types including eutonic, hypotonic, steerhorn, and cascade according to stomach contour in relation to body build. We also reviewed pathologic reports on endoscopic biopsy or surgical specimen. We studied the presence of relationship between incidence of stomach cancer and variation of stomach contour. We also examined the incidence of gastritis and gastric ulcer to the stomach contour variation. Of total 1,546 patients, eutonic stomach were 438(28.3%), hypotonic 911(58.9%), steerhorn 102(6.5%) and cascade 95(6.2%). Stomach cancer was found in 139(31.7%) of 438 eutonic stomachs, in 135(14.8%) of 911 hypotonic, in 42(41.2%) of 102 steerhorn, and in 24(36.9%) of 95 cascade (p=0.001). In hypotonic stomach, the incidence of stomach cancer was lower compared to the other three types significantly (p<0.05). Gastritis or gastric ulcer was found in 146(33.3%) of eutonic stomach, in 293(32,1%) of hypotonic, in 36(35.2%) of steerhorn, and in 26(27.3%) of cascade (p=0.640). In conclusion, gastric contour variation seems to be a factor affecting development of stomach cancer. The patients with hypotonic stomach may have lower incidence of stomach cancer than that of the other types. There was no relationship between the contour and gastritis or gastric ulcer.

• Safety and Health at Work
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• v.6 no.3
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• pp.256-262
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• 2015

Background: Heart attack is the most common cause of line-of-duty death in the fire service. Daily aspirin therapy is a preventative measure used to reduce the morbidity of heart attacks but may decrease the ability to dissipate heat by reducing skin blood flow. Methods: In this double-blind, placebo-controlled, crossover study, firefighters were randomized to receive 14 days of therapy (81-mg aspirin or placebo) before performing treadmill exercise in thermal-protective clothing in a hot room [$38.8{\pm}2.1^{\circ}C$, $24.9{\pm}9.1%$ relative humidity (RH)]. Three weeks without therapy was provided before crossing to the other arm. Firefighters completed a baseline skin blood-flow assessment via laser Doppler flowmetry; skin was heated to $44^{\circ}C$ to achieve maximal cutaneous vasodilation. Skin blood flow was measured before and after exercise in a hot room, and at 0 minutes, 10 minutes, 20 minutes, and 30 minutes of recovery under temperature conditions ($25.3{\pm}1.2^{\circ}C$, $40.3{\pm}13.7%\;RH$). Platelet clotting time was assessed before drug administration, and before and after exercise. Results: Fifteen firefighters completed the study. Aspirin increased clotting time before and after exercise compared with placebo (p = 0.003). There were no differences in absolute skin blood flow between groups (p = 0.35). Following exercise, cutaneous vascular conductance (CVC) was $85{\pm}42%$ of maximum in the aspirin and $76{\pm}37%$ in the placebo groups. The percentage of maximal CVC did not differ by treatment before or after recovery. Neither maximal core body temperature nor heart rate responses to exercise differed between trials. Conclusion: There were no differences in skin blood flow during uncompensable heat stress following exercise after aspirin or placebo therapy.

• Journal of Chest Surgery
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• v.28 no.6
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• pp.565-570
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• 1995

Seventy-three patients with isolated total anomalous pulmonary venous connection the patients associated with other major cardiac anomalies such as single ventricle, DORV[Double Outlet Right Ventricle and large VSD[Ventricular Septal Defect were excluded were underwent surgical repair from January 1980 through October 1993. There were 45 boys and 28 girls. The mean age at operation was 19.9 months[range 6 days to 24 years and mean body weight was 7.1kg[range 2.6kg to 45kg . The anomalous locations of connection were supracardiac in 38, cardiac in 21, infracardiac in 5, and mixed in 9. In 38 patients[52% , the venous drainage was obstructed. The obstruction ratios according to the connection type were as follows: 53%[28/38 in supracardiac, 52%[11/21 in cardiac, 100%[5/5 in infracardiac, 22%[2/9 in mixed type. The associated cardiac anomalies were persistent left SVC[2 , tricuspid valve regurgitation[3 , cor triatriatum[1 , and mitral cleft[1 . And associated noncardiac anomalies were imperforate anus[1 and Neil Weightman syndrome[1 . The operative mortality was 23%. The causes of death were pulmonary hypertensive crisis, perioperative myocardial failure, pneumonia with sepsis, arrhythmia and etc. The statistically significant factors in postoperative mortality were the pulmonary venous obstruction and age [p<0.01 . The operative mortality was high in groups of age under 1 month and pulmonary venous obstruction. The mean follow-up was 27.1 months. There were two late deaths. The first patient was three months old boy with supracardiac type and severe obstructive symptoms. The postoperative echocardiography was showed anastomotic stenosis and reoperations were performed twice but the patients expired due to pneumonia and sepsis. The second patient was three month old boy with supracardiac type and total correction was done and was doing well postoperatively. Eight years later, he expired suddenly due to arrhythmia. But all the other patients were in NYHA Fc I and received no medications. The 5-year survival rate excluding early expired patients is 97.1 $\pm$ 0.03 %. In conclusion, although the operative mortality of total anomalous pulmonary venous connection was relatively high compared to other major cardiac anomalies, we could expect excellent long-term results by early surgical correction.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.05a
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• pp.149-152
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• 2008

Effects of chamber configuration on combustion characteristic velocity of full-scale combustion chamber for 30-tonf-class liquid rocket engine were studied. The configurations of combustion chamber are ablative and channel cooling chamber (${\varepsilon}$=3.2) which have detachable mixing head, and single body regenerative cooling chamber which has nozzle expansion ratio of 3.5 and 12, respectively. The combustion chambers have chamber pressure of 53${\sim}$60 bar and propellant mass flow rate of 89 kg/s, and the injectors of all combustion chamber have recess number 1.0 and double-swirl characteristics. The hot firing test results at design point show that the combustion characteristic velocity of the regenerative cooling chamber which has nozzle expansion ratio of 12 is higher than that of other combustion chambers. The reasons for the above result are the increases of combustion pressure and enthalpy of kerosene which is heated due to cooling of the chamber wall before injection into the combustion field.

• Physical Therapy Korea
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• v.22 no.3
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• pp.81-90
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• 2015

This study aimed to determine the effects of Rhythmic Auditory Stimulation (RAS) using music and a metronome on the gait of stroke patients. 13 female and 15 male volunteers were randomly allocated to two groups: namely a group to receive RAS using music and a metronome group (the experimental group; $n_1=14$) and a group to receive RAS using a metronome only (the control group; $n_2=14$). The affected side was the left side in 15 subjects and the right side in 13 subjects. The mean age of the subjects was 56.6 years, and the mean onset duration of stroke was 8.6 months. Intervention was applied for 30 minutes per session, once a day, 5 times a week for 4 weeks. To measure the patients' gait improvement, we measured gait velocity, cadence, stride length, double limb support using GAITRite, body center sway angle using an accelerometer, and Timed Up-and-Go test. Functional Gait Assessment were conducted before and after the experiment. The paired t-test was used for comparisons before and after the interventions in each group. Analysis of covariance was used for comparisons between the groups after the interventions. Statistical significance was set at ${\alpha}=.05$. Within each of the two groups, significant differences in all of the dependent variables before and after the experiment (p<.05) were observed. However, in the comparison between the two groups, the experimental group showed more significant improvements in all dependent variables than the control group (p<.05). Our results also suggest that in applying RAS in stroke patients, the combination of music and a metronome is more effective than using a metronome alone in improving patients' gait.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.35 no.1
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• pp.1-12
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• 2013

Purpose: Vascular endothelial growth factor (VEGF)-C and its tyrosine kinase receptor, VEGF receptor (VEGFR)-3 are recently known to have lymphangiogenic activities in various tumor types. In this study, we determined whether the expression of lymphangiogenic factors correlate with nodal metastasis or survival in a nude mouse model of oral squamous cell carcinoma (OSCC). Methods: Three OSCC cells (KB, SCC4, SCC9) were xenografted into the right mandibular gland of athymic nude mice. The mice were followed for tumor development and growth, and the mice were sacrificed when they had lost more than 20% of their initial body weight, or the diameter of the induced tumor exceeds 20 mm. After necropsy, the murine tumors were examined histologically and radiologically (micro-positron emission tomography computed tomography) for regional or distant metastasis. We performed immunohistochemical assays with anti-VEGF-C, VEGFR-3, CD105, and D2-40 antibodies. Immunofluorescence double staining for LYVE-1/CD31 was also performed. To quantify the VEGF-C and VEGFR-3 level in the cancer tissue, Western blotting was performed. Finally, we determined the correlation between the degree of expression of VEGF-C/VEGFR-3 and the mean survival time. Results: OSCC tumor cells into the mandibular gland of the nude mice successfully resulted in the formation of recapitulating orthotopic tumor. Tumor cells of the induced tumor did not express VEGF-C. VEGF-C/VEGFR-3 expression was mainly distributed in the endothelial cells of the stromal area. There were no correlation between the degree of expression of VEGF-C/VEGFR-3 and the mean survival time of mice injected with different OSCC cell lines. Conclusion: An recapitulating orthotopic model of OSCC in nude mice was established, which copies the cervical nodal metastasis of human OSCC. Overexpression of lymphangiogenic factors seems to have no effect on survival of hosts in this in vivo experiment.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.1
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• pp.197-204
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• 2010

This paper proposes a new body-effect compensated switch configuration for low voltage and low distortion switched-capacitor (SC) applications. The proposed circuit allows rail-to-rail switching operation for low voltage SC circuits and has better total harmonic distortion than the conventional bootstrapped circuit by 19 dB. A 2-1 cascaded sigma-delta modulator is provided for performing the high-resolution analog-to-digital conversion on audio codec in a communication transceiver. An experimental prototype for a single-stage folded-cascode operational amplifier (opamp) and a 2-1 cascaded sigma-delta modulator has been implemented m a 0.25 micron double-poly, triple-metal standard CMOS process with 2.7 V of supply voltage. The 1% settling time of the opamp is measured to be 560 ns with load capacitance of 16 pF. The experimental testing of the sigma-delta modulator with bit-stream inspection and analog spectrum analyzing plot is performed. The die size is $1.9{\times}1.5\;mm$.

• The Journal of Korean Academy of Prosthodontics
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• v.28 no.2
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• pp.147-163
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• 1990

Although dental porcelain demonstrates lasting esthetic results, it suffers from inherent brittle fractures. Various techniques and materials for intraoral porcelain repair has been suggested. This study investigated the in vitro shear strength of three porcelain repair systems according to aspects of the porcelain fractures. The purpose of this study was to evaluate the shear bond strength of three porcelain repair systems(All-bond, Clearfil, Scotchprime) according to fractured surface of porcelain - fused - to - metal restorations. For this study specimens were divided into five groups : group 1 represented fracture occurred at body porcelain layer, group 2 represented fracture occurred at opaque porcelain layer, group 3 represented fracture including 1/3 of metal exposure, group 4 represented fracture including 2/3 of metal exposure, and group 5 represented all metal surface was exposed. Specimens were stored in double deionized water(24Hr, $37^{\circ}C$) and thermocycling was performed(24Hr, 1080cycles), and subjected to a shear force parallel to the repair resin and porcelain interface by use of an University Testing Machine. The results of this study were obtained as follows : 1. In group 1 and 2, bond strength was relatively high, and bond strength showing reducing tendency as exposure of metal was increased. 2. In group 1, bond strength was relatively high, and no significant differences in porcelain repair system. 3. In group 2, 3 and 4, All-bond and Clearfil provided significantly higher bond strength than scotchprime. 4. In group 5, bond strength was the lowest among all groups and especially in case if Scotchprime. 5. Cohesive failure was observed in group 1 and 2, adhesive failure was observed in group 5, and cohesive / adhesive failures were observed in group 3 and 4.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.9 no.2
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• pp.115-127
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• 1998

Laryngopharyngeal reflux(LPR) is one firm of the gastroesophageal reflux diseases(GERD). It is known to cause various kinds of otolaryngologic symptoms such as hoarseness, foreign body sensation in throat, chronic throat clearing, chronic cough, etc. Disease entities diagnosed by otolaryngologists as posterior laryngitis, globus pharyngeus should be suspected as LPR-related diseases. In this multi-center trial, we tried to evaluate the effect of cisapride(10mg tid) on LPR-related symptoms as the part I study(CIS-KOR-051) in 19 centers, and as the part II study(CIS-KOR-052) comparative evaluation of effect between cisapride(10mg tid) and ranitidine(150mg bid) on LPR-related symptoms in 4 centers. In part I study, efficacy of cisapride on LPR-related symptoms after 4 weeks was 53.5% and that of after 8weeks was 77.9% in per protocol(PPA) analysis group. In part II study, efficacy of the cisapride was much better than that of ranitidine not only from 8 weeks trial(p<0.001) but also from 4 weeks trial(p<0.021) in PPA group. In the multiple logistic regression analysis among the parameters which affect the efficacy of the treatment, cisapride prescribed group showed 10 times greater than that of ranitidine prescribed group(p<0.0001, Odds ratio : 10) in PPA group. LPR was proved by 24Hr double probe pHmetry in 13 patients out of 19 patients tested(68.4%). Thus these results indicated that inducing the improvement of motility functions could affect the amelioration of the LPR-related symptoms much better than reducing acid secretion from the stomach. And maybe it suggests that LPR-related symptoms mainly developed by the reduced motility functions of the esophagus and/or delayed gastric emptying.