• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.32 no.3
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• pp.223-228
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• 2019

We fabricated a printed Ag:CNT film as a liquid sensor for the detection of HNS (hazardous and noxious substances) in seawater. The paste required for printing was prepared using Ag powder, MWCNTs (multi-walled carbon nanotubes), and an organic binder. The heat treatment process for binder removal was optimized. In order to confirm that the sensor was operational, the resistance change characteristics in brine (3.5%) and methanol (99.8%) were assessed at $20^{\circ}C$. EDL (electrical double layer) formation and redox reactivity were confirmed as the most important reactions affect each electrical property of sensor in brine and methanol. From these results, it was determined that printed Ag:CNT film can be applied as a sensor to detect HNS in seawater.

• Journal of Oriental Neuropsychiatry
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• v.29 no.1
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• pp.35-46
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• 2018

Objectives: The aim of this trial is to evaluate the efficacy and safety of Yukwool-tang (Liuyu-tang) for the treatment of major depression in women by comparing the Yukwool-tang (Liuyu-tang)-treated group with the placebo-treated group and assessing the association of various biological factors related to depression through various outcome measures. Methods: This study is a single-center, randomized, double-blind, placebo-controlled, parallel-design clinical trial. The subjects to be selected are women between the ages of 19 and 65, and the registered subjects are to be randomly assigned to treatment with Yukwool-tang or the placebo control. The Yukwool-tang group will take 1 bottle of Yukwool-tang (30 mg) for 8 weeks, 3 times a day, before meals. The control group will take the placebo in the same way. The primary outcome to be examined will be the change between the total score after 8 weeks and the total score before the start of the study of the K-HDRS score. Secondary outcomes are assessed by the change in total score after 12 weeks of K-HDRS, K-HDRS remission rate, K-HDRS improvement rate, BDI-K, PITD, KSCL-95, ISI, STAI-K, EQ-5D, VAS, Emotional Stimulation Test, BDNF test, inflammatory cytokine and tumor necrosis factor test, intestinal microbiome test, dietary report and Beck's hopelessness scale. Results: This protocol has been approved by the IRB of Dunsan Korean Medicine Hospital of Daejeon University and is registered in the CRIS, and it is made public in advance to ensure transparency of the research process and conduct ethical clinical trials. Conclusions: Based on this protocol, when the trial is completed, its data can be used to access the validity and safety of Yukwool-tang for major depression in women, and it is also expected to be helpful in the study of the correlation between future treatment of Korean medicine for depression and related biological factors, and quality of life.

• Korean Journal of Environmental Agriculture
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• v.40 no.3
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• pp.203-210
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• 2021

BACKGROUND: Pesticides can persist in soil due to multiannual uses. To decrease the concerns for potential carry-over of such residues from treated soil during preceding crop cultivation to non-target crops grown in rotation, an uptake study of procymidone was conducted under the actual cultivation conditions in Korea. METHODS AND RESULTS: Procymidone was sprayed twice by foliar application with recommended and double dose according to the safe use guidelines for Korean cabbage up to 14 days before harvest. Arable land was kept fallow for 4 days after harvesting Korean cabbage, and spinach was cultivated as a succeeding crop. Initial residues in soil were 5.670-14.175 mg/kg that were degraded to 3.098-4.555 mg/kg until harvest of Korean cabbage, and then persisted at 1.026-1.300 mg/kg by spinach harvest. Procymidone residues in edible part of succeeding crops from soil uptake were in range of 0.020-0.048 mg/kg for recommended dose and 0.055-0.116 mg/kg for double dose. Root concentration factor (RCF) values of procymidone at different concentration ranged from 0.053 to 0.123, and translocation factor (TF) ranged from 0.176 to 0.768 for spinach. The value of TF was higher than RCF, indicating that the capability of translocation to shoot was relatively higher than that of root uptake and accumulation. CONCLUSION: Procymidone applied on Korean cabbage can be carried-over to spinach and detected at a level similar to MRL (0.05^T mg/kg). Therefore, this study suggests a follow-up study for establishment of plant back interval (PBI) of succeeding crops reflecting the actual agricultural conditions as this study.

• BMB Reports
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• v.42 no.9
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• pp.541-551
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• 2009

Amyloidogenesis defines a condition in which a soluble and innocuous protein turns to insoluble protein aggregates known as amyloid fibrils. This protein suprastructure derived via chemically specific molecular self-assembly process has been commonly observed in various neurodegenerative disorders such as Alzheimer's, Parkinson's, and Prion diseases. Although the major culprit for the cellular degeneration in the diseases remains unsettled, amyloidogenesis is considered to be etiologically involved. Recent recognition of fibrillar polymorphism observed mostly from in vitro amyloidogeneses may indicate that multiple mechanisms for the amyloid fibril formation would be operated. Nucleation-dependent fibrillation is the prevalent model for assessing the self-assembly process. Following thermodynamically unfavorable seed formation, monomeric polypeptides bind to the seeds by exerting structural adjustments to the template, which leads to accelerated amyloid fibril formation. In this review, we propose another in vitro model of amyloidogenesis named double-concerted fibrillation. Here, two consecutive assembly processes of monomers and subsequent oligomeric species are responsible for the amyloid fibril formation of $\alpha$-synuclein, a pathological component of Parkinson's disease, following structural rearrangement within the oligomers which then act as a growing unit for the fibrillation.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.23 no.8
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• pp.660-666
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• 2010

Carbon aerogels are promising materials as electrodes for electrical double layer capacitors (EDLCs). An optimum process is presented for synthesis of nanoporous carbon aerogels via pyrolyzing resorcinol-formaldehyde (RF) organic aerogels, which could be cost-effectively manufactured from RF wet gels. The major reactions between resorcinol and formaldehyde include an addition reaction to form hydroxymethyl derivatives ($-CH_2OH$), and then a condensation reaction of the hydroxymethyl derivatives ($-CH_2-$)- and methylene ether ($-CH_2OCH_2-$) bridged compounds. The textural properties of carbon aerogels obtained were characterized by nitrogen adsorption/desorption analysis and SEM and TEM. The application of the resultant carbon for electrodes of electric double layers capacitor (EDLC) in organic TEABF4/ACN electrolyte indicated that the ESR, as low as 55 $m{\Omega}$, was smaller than for commercially activated carbons. And EDLC with carbon Aerogel electrodes has an excellent stable more than for commercially activated carbons.

• 한국균학회소식:학술대회논문집
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• 2015.05a
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• pp.38-38
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• 2015

Throughout the world, clubroot disease is one of the most damaging diseases affecting Brassica oleracea. In order to perform QTL analysis of CR (clubroot resistance) loci in B. oleracea, we constructed a map, and analyzed CR-QTLs using the mean phenotypes of F3 progenies from the cross of a resistant double-haploid cabbage line (Anju) with a susceptible double-haploid broccoli line (GC). We identified one major QTL, pb-Bo(Anju)1 in C2 from Anju and four minor QTLs; pb-Bo(GC)1 in O5 from GC, pb-Bo(Anju)2, -3, -4 in C2, C3, and C7 from Anju, respectively. Additionally, we found that the accumulation of Pb-Bo(Anju)1 allele and the minor CR-QTLs is essential for resistance against various six isolates. Our finding markers closely linked to the CR-QTLs will help marker-assisted selection for CR. At present, we are undergoing toward map-based cloning for Pb-Bo(Anju)1 gene. The preliminary experiment delimited Pb-Bo(Anju)1 locus, encompassing among 450kB.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.16 no.5
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• pp.482-489
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• 2004

The purpose of this study is to reevaluate the performance of Hanji as a architectural material. Recent studies report that one of the causes of the Sick-HouseㆍSick-Building Syndrome is due to the contaminants from interior materials and the lack of ventilation. In this study, the properties of Hanji are investigated. The major focuses of this research are (1) how efficient the Hanji is for ventilation of the house and (2) whether the usage of Hanji brings required ventilation volume to the house. According to the test results, differential pressure in the air and the amount of ventilation showed linear relationship. Test results differ from various kinds of Hanji. Since houses usually have double window system, Hanji can be used to the windows system, especially for inner part of double window system. It is suggested that the combination of Hanji windows for the inner part and glass windows for outer part is very effective, and offers a solution to improvement of indoor air quality and the lack of ventilation with passive ventilation that has less energy consumption.

• Genomics & Informatics
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• v.12 no.3
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• pp.80-86
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• 2014

Foldback intercoil (FBI) DNA is formed by the folding back at one point of a non-helical parallel track of double-stranded DNA at as sharp as $180^{\circ}$ and the intertwining of two double helixes within each other's major groove to form an intercoil with a diameter of 2.2 nm. FBI DNA has been suggested to mediate intra-molecular homologous recombination of a deletion and inversion. Inter-molecular homologous recombination, known as site-specific insertion, on the other hand, is mediated by the direct perpendicular approach of the FBI DNA tip, as the attP site, onto the target DNA, as the attB site. Transposition of DNA transposons involves the pairing of terminal inverted repeats and 5-7-bp tandem target duplication. FBI DNA configuration effectively explains simple as well as replicative transposition, along with the involvement of an enhancer element. The majority of diverse retrotransposable elements that employ a target site duplication mechanism is also suggested to follow the FBI DNA-mediated perpendicular insertion of the paired intercoil ends by non-homologous end-joining, together with gap filling. A genome-wide perspective of transposable elements in light of FBI DNA is discussed.

• Journal of Korean Society of Water and Wastewater
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• v.19 no.1
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• pp.53-60
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• 2005

Ferrous cement hydrates made from hydrating Portland cement doped with Fe (II) were reported to reductively dechlorinate chlorinated organics and to reduce Cr (VI) to Cr (III). In this study, kinetics of nitrate removal by ferrous cement hydrates were investigated. Nitrate removal kinetics were characterized by experimental variables such as cement hydration, amount of cement addition, Fe (II) dose, pH, and byproducts. As a result, hydrated cement showed better performances than non-hydrated cement due to the formation of LDH (layered double hydroxide). Doping of Fe (II) into the cement was found to improve removal efficiency at high pHs by association with Fe (II) sorbed on cement hydrates as a reactive reductant. Reduction of nitrate produced ammonium as a major product, which accounted for 63.5% of the final products, and nitrite (0.15%) as a minor product. These results indicate that the developed media are effective as sorbent/reducing agents in the nitrate removal and the reaction mechanisms of nitrate removal are sorption and reduction.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7091-7094
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• 2013

DNA repair capacity is crucial in maintaining cellular functions and homeostasis. However, it can be altered based on DNA sequence variations in DNA repair genes and this may lead to the development of many diseases including malignancies. Identification of genetic polymorphisms responsible for reduced DNA repair capacity is necessary for better prevention. Homologous recombination (HR), a major double strand break repair pathway, plays a critical role in maintaining the genome stability. The present study was performed to determine the frequency of the HR gene XRCC3 Exon 7 (C18067T, rs861539) polymorphisms in Saudi Arabian population in comparison with epidemiological studies by "MEDLINE" search to equate with global populations. The variant allelic (T) frequency of XRCC3 (C>T) was found to be 39%. Our results suggest that frequency of XRCC3 (C>T) DNA repair gene exhibits distinctive patterns compared with the Saudi Arabian population and this might be attributed to ethnic variation. The present findings may help in high-risk screening of humans exposed to environmental carcinogens and cancer predisposition in different ethnic groups.