• Title/Summary/Keyword: Dose reduction

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A Study of a Non-commercial 3D Planning System, Plunc for Clinical Applicability (비 상업용 3차원 치료계획시스템인 Plunc의 임상적용 가능성에 대한 연구)

  • Cho, Byung-Chul;Oh, Do-Hoon;Bae, Hoon-Sik
    • Radiation Oncology Journal
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    • v.16 no.1
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    • pp.71-79
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    • 1998
  • Purpose : The objective of this study is to introduce our installation of a non-commercial 3D Planning system, Plunc and confirm it's clinical applicability in various treatment situations. Materials and Methods : We obtained source codes of Plunc, offered by University of North Carolina and installed them on a Pentium Pro 200MHz (128MB RAM, Millenium VGA) with Linux operating system. To examine accuracy of dose distributions calculated by Plunc, we input beam data of 6MV Photon of our linear accelerator(Siemens MXE 6740) including tissue-maximum ratio, scatter-maximum ratio, attenuation coefficients and shapes of wedge filters. After then, we compared values of dose distributions(Percent depth dose; PDD, dose profiles with and without wedge filters, oblique incident beam, and dose distributions under air-gap) calculated by Plunc with measured values. Results : Plunc operated in almost real time except spending about 10 seconds in full volume dose distribution and dose-volume histogram(DVH) on the PC described above. As compared with measurements for irradiations of 90-cm 550 and 10-cm depth isocenter, the PDD curves calculated by Plunc did not exceed $1\%$ of inaccuracies except buildup region. For dose profiles with and without wedge filter, the calculated ones are accurate within $2\%$ except low-dose region outside irradiations where Plunc showed $5\%$ of dose reduction. For the oblique incident beam, it showed a good agreement except low dose region below $30\%$ of isocenter dose. In the case of dose distribution under air-gap, there was $5\%$ errors of the central-axis dose. Conclusion : By comparing photon dose calculations using the Plunc with measurements, we confirmed that Plunc showed acceptable accuracies about $2-5\%$ in typical treatment situations which was comparable to commercial planning systems using correction-based a1gorithms. Plunc does not have a function for electron beam planning up to the present. However, it is possible to implement electron dose calculation modules or more accurate photon dose calculation into the Plunc system. Plunc is shown to be useful to clear many limitations of 2D planning systems in clinics where a commercial 3D planning system is not available.

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A Study on the Difference of Scattered Rays with or Without Gonadal Shielding During Chest Computed Tomography (흉부 전산화 단층 촬영 검사 시 발생하는 생식선 차폐 유무에 따른 산란 선량 차이에 관한 연구)

  • Kwak, Jong Hyeok;Kim, Gyeong Rip;Sung, Hyun Chul;Kim, Seung Won;Song, Geun Sung;Choi, Min Gyeong;Lee, Sang Weon
    • Journal of the Korean Society of Radiology
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    • v.15 no.2
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    • pp.109-115
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    • 2021
  • This study is a study on the difference in dose according to the presence or absence of gonadal shielding of scattered rays generated during chest computed tomography examination, and the scattered dose of the examination site was measured by placing the RadEye G-10 device in the center of the phantom. When the gonads are not shielded, the scattering lines of the whole, both sides, posterior and gonads are measured and Xenolite nolead Apron (0.35 mm PB), Xenolite nolead Apron (front 0.35 mm PB Mix back 0.25 mm PB, Skirt overlap), Half Apron After shielding with (0.5 mm PB), each scattered dose was measured. During chest computed tomography, the scattered dose of the test site was measured at 272 μSv, and when not shielded with Apron, the average total was 43 μSv, left 81 μSv, right part 82 μSv, posterior part 38.8 μSv, and Gonad part 16 μSv. Became. Xenolite nolead Apron shielded only the upper part and measured all 11.2 μSv, left part 43.1 μSv, right part 45.3 μSv, posterior part 12 μSv and Gonad part 5.2 μSv. Xenolite nolead Apron (Skirt overlap) covered the Pelvis area 360° and the dose was measured to be 5.6 μSv in the whole, 22.4 μSv in the left, 15.7 μSv in the right side, 6 μSv in the posterior part, and 3.2 μSv in the Gonad part. Xenolite nolead Apron (Skirt overlap) covered the Pelvis area 360° and the dose was measured to be 5.6 μSv in the whole, 22.4 μSv in the left, 15.7 μSv in the right side, 6 μSv in the posterior part, and 3.2 μSv in the Gonad part. When measuring only the upper part with Half Apron, the total measurement was 10.7 μSv, the left part 42.6 μSv, the right part 40.6 μSv, the posterior part 11.3 μSv, and the Gonad part 4.7 μSv. The method of 360° shielding of the pelvic area showed a dose reduction of more than 80%, and a dose reduction effect of more than 70% was shown when all shielding was performed. In all computerized tomography examinations, research to reduce the exposure dose and various shielding devices were used. It is believed that continuous research on the technique is needed.

Comparison with ABCHES and Abdomen Compression Device in Respirational Radiation Therapy on Patients in Hepatocellular Carcinoma (간세포암 환자에서 ABCHES와 복부압박장비의 적용한 호흡동조방사선 치료의 유용성 비교)

  • Cho, Yoon-Jin;Byun, Sang-Joon;Kim, Young-Jae
    • Journal of the Korean Society of Radiology
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    • v.6 no.5
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    • pp.395-402
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    • 2012
  • 4D-Radiation Therapy is the optimal treatment to track moving organs(tumor) and give the appropriate prescription dose to tumor and low radiation dose to normal tissue surrounding tumor volume. The ABCHES is a 4DRT devices maintaining shallow breathing to patients. It allows the tumor's movement was minimize. Meanwhile, Abdominal compression device is limited the breath compressing abdomen on patients. In this paper we will quantitative analysis the movement of tumor on only ABCHES versus ABCHES with Abdomal compression device and Analysis tumor dose and normal tissue's dose by Dose Volume Histogram on two parts. The result of Comparision ABCHES and ABCHES with Abdominal compression device, SI(Superior-Inferior) direction, AP(Anterior-Posterior) direction and LR(Left-Right) direction was limited 1.0 mm, 0.2 mm, 0.2 mm(average). and also reduction rate of voluume in HPTV was $16{\pm}2%$, and LPTV was $15.8{\pm}0.8%$ under only using ABCHES and ABCHES with compression. The analysis dose volume histogram was more radiation dose in ABCHES and abdominal compression device than only using ABCHES, and less normal tissue-ipsilateral lung, whole lung, kidney-dose in ABCHES and abdominal compression device than only using ABCHES. The overall analysis was ABCHES with abdominal compression better than only using ABCHES method. In hereafter it will be studies that limitation of ABCHES and abdomonal compression device. In other words, patient's discomfort on compression intensity, method of application on patient with inaccurate respiration cycle.

Skin Radioprotector (Diethone) Modifying Dermal Response of Radiation on Rats (방사선 보호제(Diethone)의 랫드 피부반응에 대한 수식작용)

  • Hong, Seong-Eon;Urahashi, Shingo;Kamata, Rikisaburo
    • Radiation Oncology Journal
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    • v.7 no.1
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    • pp.15-22
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    • 1989
  • Investigations were carried out into the time-and dose-related changes in acute skin reaction following graded single dose (20,30 and 40 Gy) of x-ray irradiation in Wistar rats, in order to evaluate the radioprotective effect of Diethon on skin. For the duration of skin response over 1. 5 score in dose of 40 Gy, the Diethone group of 24.7 days was significantly different (p<0.02) from that of control (29.8 days) and vaseline (29.2 days) groups, it was $17.1\%$ diminution of skin response period compared with that of control group. By the averaging daily scores for 10 days during peak skin reaction the mean scores were obtained. Mean score of Diethone group $(2.43\pm0.22)$ was significantly different (p<0.01) from that of control $(2.91\pm0.23)$ and vaseline $(2.81\pm0.18)$ groups of 40Gy dose. By iso-effect dose obtained at level of 2.5 score the dose reduction factor (DRF) was 1.41 which reduced radiation dose of $41\%$ by radioprotective effect of Diethone. From this experimental data, it may be possible to give higer radiation dose to large and/or radioresistant tumor mass rather than conventional treatment doses for improving therapeutic ratio by using topical application of skin radioprotector.

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Effects of Gamma-ray Irradiation on Radio Sensitivity in Oat (Avena sativa) (감마선 조사가 귀리(Avena sativa)의 감수성에 미치는 영향)

  • Ryu, Jaihyunk;Kwon, Soon-Jae;Im, Seung Bin;Jeong, Sang Wook;Ahn, Joon-Woo;Kim, Jin-Back;Choi, Ki Choon;Kim, Won Ho;Kang, Si-Yong
    • Korean Journal of Plant Resources
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    • v.29 no.1
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    • pp.128-135
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    • 2016
  • This study examined radiation damage and the optimal gamma-ray dose for mutation breeding in oat (Avena sativa L. cv. Samhan). The seed germination rate decreased as the dose increased over 500 Gy. The median lethal dose (LD50) was approximately 392 Gy. The median reduction dose (RD50) for plant height, tiller number, root length, and flash weight was 411, 403, 394, and 411 Gy, respectively. The optimal dose of gamma irradiation for inducing oat mutation appears to be in the range 300-400 Gy. We performed the comet assay to observe nuclear DNA damage induced by gamma-ray irradiation. This assay showed a clear difference with gamma-ray treatments. DNA damage increased temporarily 7 days after treatment depending on the dose, while no significant difference was identified in response to 300 Gy 30 days after the gamma-ray treatments. The growth characteristics of the M2 generation decreased as the dose increased over 400 Gy.

Development and utility evaluation of new Multi-Leaf Collimator for Diagnostic X-ray Equipment

  • Ji, Hoon;Han, Su Chul;Baek, Jong Hyeun;Lee, Dong Hoon;Park, Seungwoo
    • Journal of Electrical Engineering and Technology
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    • v.13 no.2
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    • pp.936-942
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    • 2018
  • The diagnostic multi-leaf collimator preventing unnecessary dose from entering into patients during the diagnostic examination was made in this study. The movement of the entire 50 leaves was embodied with the group of 25 ones thereof configured in a pair facing each other on the left and right of the median line. Dimensions of the length, width, and height of each shielding leaf were $5{\times}0.5{\times}0.5cm^3$ resulting in the maximum boost field of $10{\times}10cm^2$. The material of multi-leaf collimator had the excellence on the machinability with the use of the SKD-11 alloy tool steel having the high wear resistance against frequent movement, and it was devised to control both-side's shielding leaves by moving 2 motors unlike existing remedial multi-leaf collimator that use as many motors as the number of 50 shielding leaves. Thereafter, the transmission dose of leaves, cross-leaf leakage dose, and inter-leaf leakage dose were measured by the developed multi-leaf collimator attached to X-ray equipment. An ionization chamber was used to detect doses there from, and the comparative analysis was carried out by means of the radiographic film that was easy to detect the dose leakage in between each leaf. Results obtained from the test conducted in comparative analysis yielded approximately 98%, 96%, and 94% of shielding efficiency realized at each level of energy of 80kV, 100kV, and 120kV it was confirmed there was no dose leakage resulted from the varied level of irradiation energy. Thus the multi-leaf collimator to be developed based on this study is thought that it could fully reduce the unnecessary dose to patients in the diagnostic test and the shielding efficiency thereof is expected to be increasing if it is made in a miniaturized form with a way of increasing the thickness of each leaf later for an extended application to general diagnostic purposes.

Reducing Methods of Patient's Exposed Dose Using Auto Exposure Control System in Digital Radiography (디지털 방사선장비에서 자동노출제어 사용 시 환자피폭선량 감소 방안)

  • Shin, Seong-Gyu
    • Journal of radiological science and technology
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    • v.36 no.2
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    • pp.111-122
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    • 2013
  • This study was carried out to reduce patient dose through focus-detector distance, kilovoltage, and a combination of copper filters. In the C, L-spine lateral, Skull AP views were obtained by making changes of 60-100 kV in tube voltage and of 100-200 cm in focus-detector distance and by adding a copper filter when using an auto exposure control device in the digital radiography equipment. The incident dose showed 90 kV, 0.3 mmCu in C-spine lateral with 0.06 mGy under the condition of 200 cm; 100 kV, 0.3 mmCu with 0.40 mGy under the condition of 200 cm and 90 kV 0.3 mmCu in Skull AP with the lowest value of 0.24 mGy under the condition of 140 cm. It was observed that entrance surface dose decreased the most when was increased by 150 cm, 70 kV (C-spine lateral), 81 kV (L-spine lateral). It was also found out that as the between the focus-detector increased in the expansion of the video decreased but the difference was not significant when the distance was 180 cm or more. Skull AP showed the most reduction in the entrance surface dose when the tube voltage was changed by 80 kV, 0.1 mmCu, and 120 cm. Therefore, when using the automatic exposure control device, it is recommended to use the highest tube voltage if possible and to increase focus-detector distance at least by 150~200 cm in wall and 120~140 cm in table in consideration of the radiotechnologist's physical conditions, and to combine 0.1~0.3 mmCu and higher filters. It is thus expected to reduce patient dose by avoiding distortion of images and reducing the entrance surface dose.

Effects of Gamma-ray Irradiation on Growth Characteristics and DNA Damage in Licorice (Glycyrrhiza uralensis) (감마선 조사가 감초(Glycyrrhiza uralensis)의 초기 생육 및 DNA 손상에 미치는 영향)

  • Ryu, Jaihyunk;Im, Seung Bin;Kim, Dong Sub;Ahn, Joon-Woo;Kim, Jin-Baek;Kim, Sang Hoon;Kang, Si-Yong
    • Journal of Radiation Industry
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    • v.8 no.2
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    • pp.89-95
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    • 2014
  • This study was conducted to determine the optimal dose of gamma-ray on the growth and nucleus DNA damage for mutation breeding in licorice. Gamma-rays irradiated to dry seeds with various doses (0 to 1000 Gy). Significant decreases in germination rate (%), survival rate (%) and growth characteristics (plant height, number of leaves, root length and fresh weight) were observed by dose of increased. $LD_{50}$ (lethal dose) was approximately 400 Gy to 500 Gy. Also, reduction doses ($RD_{50}$) of plant height, number of leaves, root length and flash weight were 428 Gy, 760 Gy, 363 Gy and 334 Gy, respectively. It is supplest that the optimal dose of gamma irradiation for licorice mutation induction might be about 400 Gy in this study. We also conducted comet assay to observe nucleus DNA damage due to gamma irradiation. In comet assay, a clear difference was identified over 300 Gy treatments. With increasing doses of gamma-ray in the range of 100 to 1000 Gy, the rate of head DNA was decreased significantly from 92.88% to 73.09%. Tail length(${\mu}m$) was increased as the dose of increased over 300 Gy. Growth characteristics (Germination rate, Survival rate, plant height, number of leaves, root length and fresh weight) were highly negatively ($P{\leq}0.01$) correlated with dose. While the tail length was highly positively ($P{\leq}0.01$) correlated with dose.

The Necessity of Resetting the Filter Criteria for the Minimization of Dose Creep in Digital Imaging Systems (디지털 영상 시스템에서 선량 크리프 최소화를 위한 부가 필터 두께 권고 기준의 재설정에 대한 연구)

  • Kim, Kyo Tae;Kim, Kum Bae;Kang, Sang Sik;Park, Ji Koon
    • Journal of the Korean Society of Radiology
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    • v.13 no.5
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    • pp.757-763
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    • 2019
  • Recently, Following the recent development of flat panel detector with wide dynamic ranges, increasing numbers of healthcare providers have begun to use digital radiography. As a result, filter thickness standards should be reestablished, as current clinical practice requires the use of thicknesses recommended by the National Council on Radiation Protection and Measurements, which are based on information, acquired using conventional analog systems. Here we investigated the possibility of minimizing dose creep and optimizing patient dose using Al filters in digital radiography. The use of thicker Al filters resulted in a maximum 19.3% reduction in the entrance skin exposure dose when medical images with similar sharpness values were compared. However, resolution, which is a critical factor in imaging, had a significant change of 1.01 lp/mm. This change in resolution is thought to be due to the increased amount of scattered rays generated from the object due to the X-ray beam hardening effect. The increase in the number of scattered rays was verified using the scattering degradation factor. However, the FPD, which has recently been developed and is widely used in various areas, has greater response to radiation than analog devices and has a wide dynamic range. Therefore, the FPD is expected to maintain an appropriate level of resolution corresponding to the increase in the scattered-ray content ratio, which depends on filter thickness. Use of the FPD is also expected to minimize dose creep by reducing the exposure dose.

A Study on the Reduction of Absorbed Dose through the Insertion of a Shielding Material in the Intraoralsensor of Dental Radiography (치과 방사선촬영 시 구내 센서 내 차폐체 삽입을 통한 피폭선량 감소 연구)

  • Kim, A Yeon;Lee, Seung-Jae
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.273-279
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    • 2022
  • In order to reduce the absorbed dose given to the patient during dental radiography, a sensor that inserts a shield into the intraoralsensor was designed. Using the designed sensor, the change in absorbed dose depending on whether or not a shield was used was evaluated. The system used to evaluate the absorbed dose is VEX-S300C from Vatech, and the energy spectrum of X-rays was obtained through SPEKTR simulation based on the irradiation conditions of 65 kV, 3 mA, and 0.15 sec, and the number of photons for each energy was derived. After designing the system through Genat4 Application for Tomographic Emission(GATE) simulation, the energy spectrum obtained was used as a radiation source to calculate the absorbed dose. Lead was used for the shield, and simulations were performed at 0.1 mm thickness intervals from 0.1 mm to 0.5 mm was evaluated. In the case of using an X-ray field with a diameter of 60 mm, the decrease in absorbed dose according to the presence or absence of a shield decreased exponentially as the thickness of the shield increased. In addition, when a 20 mm × 30 mm field was used, the absorbed dose was significantly reduced even when no shield was used, and it was confirmed that the absorbed dose was further reduced when a shield was used.