• Title/Summary/Keyword: Dong Hae

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Acute Oral Toxicity and Skin Irritation Studies on Natural Dyes Extracted from Chrysanthemum (국화로부터 추출한 천연염료에 대한 급성경구독성 및 피부자극성 시험에 대한 연구)

  • Kwon, Jung-Ki;An, In-Jung;Lee, Jin-Seok;Kim, Hae-Ri;Park, Ha-Seung;Kim, Dong-Chan;Choi, Byung-Jun;Lee, Kyu-Min;Park, Yong-Jin;Jung, Ji-Youn
    • Journal of Food Hygiene and Safety
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    • v.27 no.2
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    • pp.188-193
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    • 2012
  • This study was designed to evaluate to acute oral toxicity and skin irritation of Chrysanthemum dye in Sprague-Dawley (SD) rats. SD rats were orally treated with Chrysanthemum dye at a dose of 0, 1 and 2 ml/kg body weight. After oral administration, the rats were observed for 14days. In primary skin irritation test, SD rats were dermally treated with Chrysanthemum dye and observed for 3 days. To ensure the safety of Chrysanthemum dye such as the following were observed and tested. We examined the body weight, the feed intake, the clinical signs, the ophthalmological test, the histopathological test, the mortality and skin irritation. As a result, no significant differences were found in body weight, feed intake and histopathological test between control and Chrysanthemum dye treated group. In the result of skin irritation test, Chrysanthemum dye did not induce erythema and edema after topical application. Primary irritation index was "0" in the test. Therefore, it is suggested that Chrysanthemum dye has no effect on acute toxicity and side effect in SD rats and is non-irritant material based on the score "0" of primary irritation index.

A Gear Shape of a Midwater Trawl and Its Change (중층트롤의 어구형상과 그 변화)

  • Park, Hae-Hoon;Yoon, Gab-Dong
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.38 no.3
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    • pp.209-216
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    • 2002
  • How to estimate the shape of trawl net and ropes of a midwater trawl on full scale was described by implementing a three-dimensional semi-analytic treatment of a towing cable system with the field experiments obtained with the Scanmar system. The shape of trawl net from wingend to the beginning of codend was assumed to be of form $\chi$$^2$/ae$^2$+ y$^2$/be$^2$=(z - c)$^2$/c$^2$, and that of the ropes attached behind otter boards be of form yr = $A\chi$rB. In case of warp length 300m long, the volume of trawl net, the ratio of net height to net width at the mouth of the trawl net, and the inclination angle of float rope were estimated according to the change of towing speed. The volume and the distance between wingtips were increased with increasing towing speed. And the inclination angle of float (or ground) rope was slightly decreased with increasing towing speed.

The Development of Portable Digital X-ray Power Supply Unit for Emergency Medical Services (응급의료에서 이용될 휴대용 디지털 X-ray 전원장치 개발)

  • Cho, Dong-Heon;Koo, Kyung-Wan;Yong, Hae-Sool
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.20 no.1
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    • pp.125-131
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    • 2006
  • The existing X-ray generators are either ones which are settled at fixed places or ones which are movable to sick rum. Movable generators can be very useful according to the circumstances of patients, but there remains a restraint that AC220[V] in the hospitals must be provided. When examining a first-aid patient who stays distant from the hospital or when grouping patients caused by disaster, the services of doctors at emergency centers should be very restrictive. Hence, this study developed a portable digital X-ray power supply unit that are utilizable at the accident spot or in a moving ambulance. By using the nit, the information of patients can be transmitted to the emergency center on the spot and thereby doctors can make a correct diagnosis. The properties of the unit are as follows: First, portable batteries(DCl2[V]) are utilized as electric source for the wit. Second PIC16F84A is utilized as control circuit in order to guarantee considerable reliance and to provide various functions. This portable digital X-ray power supply unit is expected to contribute to the emergency medical service system to be more advanced.

A Study on the Total Mercury Content in Fresh-Water Fishes (담수어중(淡氷魚中)의 총수은함량(總水鎭含量)에 관(關)한 연구(硏究))

  • Shon, Dong-Hun;Hong, Soon-Gag;Song, Chul-Yong;Jeon, Sang-Rin
    • Korean Journal of Food Science and Technology
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    • v.14 no.2
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    • pp.168-173
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    • 1982
  • The present study was carried to observe the total mercury contents in fresh-water fishes which were collected from 24 streams in the South-East area, Korea. These total mercury contents were determined by quartz tube combustion gold amalgamation method. The value of total mercury contents in collected fresh-water fishes ranged from 0.02ppm to 0.12ppm and the mean value were 0.07ppm. The total value of mercury contents differed with the fish species showing 0.09ppm in Carassius auratus, 0.10ppm in Coilia ectenes, 0.11ppm in Moroca lagowskii and Squalidus majime and 0.12ppm in Cobitis taenia which were highly more than the mean value of collected fishes. The mean value of the total mercury contents in the Yeong Il Gun (0.09PPm), Gim Hae Gun (0.08ppm) and Meong Ju Gun (0.08ppm) were highly detected than those of other surveyed areas.

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Survey on the Educational Needs for Smartphone Based Emergency Situations - Targeting Parents with Elementary School Children (스마트폰 기반 응급상황 대처 교육에 대한 요구도 조사 - 초등학생 자녀를 둔 부모를 대상으로)

  • Min, Hae Young;Lee, Jung Min
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.2
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    • pp.259-267
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    • 2020
  • This study investigates the educational needs of parents of elementary school children, who use smartphones for emergencies. This is a descriptive cross-sectional study, and data of 200 parents of students under the 6th grade was collected from October 17 to 27, 2017. The study results indicate that 67.5% parents visited the emergency department due to a child's emergency accident. Of these, 74% respondents replied that they were unaware of how to deal with the emergency at that instance. Most parents had never received education, and were using smart-phones to acquire information on first aid. Ed. Notes: Do you mean education in general (i.e. Most parents were uneducated) or do you mean 'education for emergencies'? Please revise for more clarity. Parents' demand for education on child emergency response scored high, with an average of 3.40 (±0.42) out of 4 points. Among the educational categories, "the management of foreign body airway obstruction and cardiopulmonary resuscitation (CPR)" scored the highest average for educational needs (3.64±0.52). This research provides baseline information for understanding the educational needs of parents for first aid for the child. Our findings indicate that the smartphone is potentially an effective educational tool for parents.

A Study on the Interrelation Between Serum Cholesterol level and Essential Hypertension, Liver Disease and Body weight (혈청(血淸)콜레스테롤 농도(濃度)와 본능성고혈압(本態性高血壓), 간기능장애(肝機能障碍) 및 체중(體重)과의 상관관계(相關關係)에 대한 검토(檢討))

  • Kim, Myung-Hae
    • The Journal of the Korean life insurance medical association
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    • v.2 no.1
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    • pp.135-142
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    • 1985
  • For the past 10 years, the socioeconomic status of our country was markedly improved. Accordingly, our foodintake patterns and other alt parts are preparing to blance with developed countries. Especially, be westernizing or improving our foodintake patterns, we intake much fat diet(animal food) while our physical activities decrease and alcohol consumtion's population, smoking population gradually increase. For such reasons, the population of obese tendency and cardiovascular diseases are increased. According to recent reports, among all death causes in our country, cardiovascular diseases(hypertension, hypertensive cardiovascular diseases, ischemic heart diseases) occupyd top rank, we know. I(the author) studied the inter-relation between serum cholesterol level which is the important factor of the cardiovascular diseases and essential hypertension liver diseases, hyperglycemia, some cardiac problems which are main decline causes in life insurance's medical assessment, and body weight distribution. Studied samples were selected on 4,313 cases(male; 1,791, female; 2,522) who were tested liver function test from June, 11th, 1980 to Dec., 31st, 1983 on our medical department's laboratory. I selected two groups in those cases: one group was serum cholesterol level 180mg/dl over(11% of whole LFT examed cases: No=502 cases), the other group was serum cholesterol level 120-160mg/dl(No= 502 cases). For convenience, the group of serum cholesterol level 180mg/dl over was "A" the other group was "B", I described. All examed persons of LFT were resident m Tae-Jon city in that time. On the result, 1) Decline rate is 10.5% on the "A" group, 5.9% on the "B" group. "A" group reveals 1.8 times higher than "B" group. 2) On decline causes, Essential hypertension is 4.0 times higher on the "A" group than "B", liver function's abnormalities are 2.0 times higher on "A" group than "B" and other diseases are same on "A" and "B". On the "A" group, essential hypertension is considerably higher than "B" group. 3) On the body weight distribution, the cases of 70kg(B.W.) over is 19.7% on "A", 10.6% on "B" group. Obese tendency is 1.8 folds higher on "A" group than "B" group. Studing the result, we find high serum cholesterol concentration is closely related with essential hypertension, obese tendency and liver function's abnormalities on the life insurance's medical examination part, also. On the future, we will more carefully consider the serum cholesterol concentration on our medical examnination and assessment of life insurance, I think.

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Preference and Readability of Hangul Fonts in the Presbyopic Age (노안 연령에서 한글서체의 선호도와 가독성 평가)

  • Jeung, Shinhae;Son, Jeong-Sik;Hwang, Hae-Young;Kim, Seong Kun;Yu, Dong-Sik
    • Journal of Korean Ophthalmic Optics Society
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    • v.18 no.2
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    • pp.149-156
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    • 2013
  • Purpose: The aim of this study was to determine a suitable type and size of Hangul fonts for printed materials in the presbyopic age. Methods: Based on the most common Hangul fonts used today, three types of fonts were used Hamchrombatang, Sinmoonmyungjo and Sinmyungjo at small font sizes in the range 9-11 point (pt). Subjects were 101 volunteers aged 41 through 85 years. Near visual acuity (VA) was corrected to read VA 0.5 at 40 cm after distance correction. The subjects were asked to read words containing 88 characters in 10 pt after a question about preference. Readability was assessed by reading rate that was calculated as the number of words read correctly in one minute (words per minute, wpm). Results: The most preferred font type was Simmyungjo at small font sizes. Although preferred font sizes were different in each font type, Sinmyungjo was generally preferred at 10 pt more than other fonts. Hamchrombatang and Sinmyungjo were read significantly faster than Sinmoonmyungjo. There was a weak negative relationship between readability and age in Sinmyungjo. In comparing between the top 10% and the bottom 10% group sorted by reading rate, the top group showed lower average age and addition than the bottom group, however there were no significant differences in reading rate among the fonts. Conclusions: Although increasing age tends to be low in readability for Sinmyungjo, in the light of preferred font and readability, it is recommended to use a 10 pt Sinmyungjo font in printed materials for the presbyopic age.

Effect of Phenobarbital Pretreatment on the Hepatotoxicity of Carbon Tetrachloride in Rat (Phenobarbital 전처치가 사염화탄소 급성중독 흰쥐 간세포의 구조에 미치는 영향)

  • Byun, Young-Soo;Nam, Hae-Joo;Kim, Mi-Jin;Kim, Dong-Suk;Choi, Won-Hee;Lee, Tae-Sook
    • Journal of Yeungnam Medical Science
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    • v.9 no.1
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    • pp.137-148
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    • 1992
  • The purpose of this study was to evaluate the influence of phenobarbital(PB) on hepatotoxic effect of carbon tetrachloride($CCl_4$) which induces centrilobular necrosis in liver. Rats were injected intraperitoneally $CCl_4$ dissolved in olive oil by a dose of 0.4mg/kg. For change related to PB pretreatment, rats were injected $CCl_4$ 0.4mg/kg after PB pretreatment. The liver samples were taken in 6, 12, 24, 48, 72, and 120 hours after $CCl_4$ and/or FB injection. Extracted liver tissue was examined with light and electron microscopes. The results were sumarized as follows : 1. Light microscopic findings : In $CCl_4$ group, centrilobular necrosis developed from 6 hours after injection, was the most severe in 48 hours, and recovered after 72 hours. In addition to necrosis, fatty change and pale cell change were accompanied. In PB-$CCl_4$ group, necrosis occurred from 6 hours after $CCl_4$ injection and continued to 72 hours, and the degree of necrosis was more severe than that of $CCl_4$ group and pale cell change was decreased. 2. Electron microscopic findings: In $CCl_4$ group, the early principal change was clumping and vesicular dilatation of endoplasmic reticulum. In PB-$CCl_4$ group, the degenerative change of endoplasmic reticulum was aggrevated and the mitochondria also revealed severe degenerative change. According to the results, it was revealed that $CCl_4$ hepatotoxicity primarily began with the damage of endoplasimic reticulum, then damage of other cell organelles and cell necrosis followed, and these cytotoxic effects were aggrevated by PB pretreatment.

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Histopathologic Consideration of Hepatocellular Carcinoma (간세포암에 대한 병리학적 고찰)

  • Nam, Hae-Joo;Kim, Dong-Suk;Choi, Won-Hee;Lee, Tae-Sook
    • Journal of Yeungnam Medical Science
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    • v.9 no.2
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    • pp.351-358
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    • 1992
  • Hepatocellular carcinoma represents approximately 90% of the primary liver cancers. Recently, its incidence tends to be increased. Thirty seven cases from 1986 to 1991 diagnosed as hepatocellular carcinoma by resection were analized to know their histopathologic features and related clinical findings. The average age at the time of resection was 53.1 years, with frequent occurrence in third and fourth decades. Microscopically, the trabecular type was the most frequent growth pattern(35.1%) and classic hepatocyte-like cell type was the most frequent cell type(75.7%). The tumors are mainly moderately differentiated and frequently associated with liver cirrhosis. In comparison of cytologic differentiation with liver cirrhosis, there was a tendency for well-differentiated tumors to arise in cirrhotic livers more often than poorly differentiated tumors, and the tendency was statistically significant. But differentiation and tumor size did not show significant correlation. Also statistically significant correlation were not observed between the level of alpha-fetoprotein and tumor size, and between the level of alpha-fetoprotein and differentiation.

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Paleoenvironmental Changes in the Northern East China Sea and the Yellow Sea During the Last 60 ka

  • Nam, Seung-Il;Chang, Jeong-Hae;Yoo, Dong-Geun
    • The Korean Journal of Quaternary Research
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    • v.17 no.2
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    • pp.165-165
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    • 2003
  • A borehole core ECSDP-102 (about 68.5 m long) has been investigated to get information on paleoenvironmental changes in response to the sea-level fluctuations during the period of late Quaternary. Several AMS $\^$14/C ages show that the core ECSDP-102 recorded the depositional environments of the northern East China Sea for approximately 60 ka. The Yangtze River discharged huge amounts of sediment into the northern East China Sea during the marine isotope stage (MIS) 3. In particular, $\delta$$\^$13/Corg values reveal that the sedimentary environments of the northern East China Sea, which is similar to the Holocene conditions, have taken place three times during the MIS 3. It is supported by the relatively enriched $\delta$$\^$13/Corg values of -23 to -21$\textperthousand$ during the marine settings of MIS 3 that are characterized by the predominance of marine organic matter akin to the Holocene. Furthermore, we investigated the three Holocene sediment cores, ECSDP-101, ECSDP-101 and YMGR-102, taken from the northern East China Sea off the mouth of the Yangtze River and from the southern Yellow Sea, respectively. Our study was focused primarily on the onset of the post-glacial marine transgression and the reconstructing of paleoenvironmental changes in the East China Sea and the Yellow Sea during the Holocene. AMS $\^$14/C ages indicate that the northern East China Sea and the southern Yellow Sea began to have been flooded at about 13.2 ka BP which is in agreement with the initial marine transgression of the central Yellow Sea (core CC-02). $\delta$$\^$18/O and $\delta$$\^$13/C records of benthic foraminifera Ammonia ketienziensis and $\delta$$\^$13/Corg values provide information on paleoenvironmental changes from brackish (estuarine) to modem marine conditions caused by globally rapid sea-level rise since the last deglaciation. Termination 1 (T1) ended at about 9.0-8.7 ka BP in the southern and central Yellow Sea, whereas T1 lasted until about 6.8 ka BP in the northern East China Sea. This time lag between the two seas indicates that the timing of the post-glacial marine transgression seems to have been primarily influenced by the bathymetry. The present marine regimes in the northern East China Sea and the whole Yellow Sea have been contemporaneously established at about 6.0 ka BP. This is strongly supported by remarkably changes in occurrence of benthic foraminiferal assemblages, $\delta$$\^$18/O and $\delta$$\^$13/C compositions of A. ketienziensis, TOC content and $\delta$$\^$13/Corg values. The $\delta$$\^$18/O values of A. ketienziensis show a distinct shift to heavier values of about 1$\textperthousand$ from the northern East China Sea through the southern to central Yellow Sea. The northward shift of $\^$18/O enrichment may reflect gradually decrease of the bottom water temperature in the northern East China Sea and the Yellow Sea.

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