• Title/Summary/Keyword: Dong Hae

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Utility of the APACHE II Score as a Neurologic Prognostic Factor for Glufosinate Intoxicated Patients (Glufosinate 중독 환자의 신경학적 예후 인자로서 APACHE II Score의 유용성)

  • Yoo, Dae Han;Lee, Jung Won;Choi, Jae Hyung;Jeong, Dong Kil;Lee, Dong Wook;Lee, Young Joo;Cho, Young Shin;Park, Joon Bum;Chung, Hae Jin;Moon, Hyung Jun
    • Journal of The Korean Society of Clinical Toxicology
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    • v.14 no.2
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    • pp.107-114
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    • 2016
  • Purpose: The incidence of glufosinate poisoning is gradually increasing, and it can be fatal if severe poisoning occurs. However, factors useful for predicting the post-discharge neurological prognosis of patients who have ingested glufosinate have yet to be identified. Our objective was to evaluate the utility of the acute physiology and chronic health evaluation (APACHE) II score measured in the emergency department for predicting the neurological prognosis. Methods: From April 2012 to August 2014, we conducted a retrospective study of patients who had ingested glufosinate. The outcome of the patients at discharge was defined by the Cerebral Performance Category Score (CPC). The patients were divided into a good prognosis group (CPC 1, 2) and a poor prognosis group (CPC 3, 4, 5), after which the APACHE II scores were compared. The Hosmer-Lemeshow test and the area under the receiver operating characteristic (ROC) curve from patients determined calibration and discrimination. Results: A total of 76 patients were enrolled (good prognosis group: 67 vs poor prognosis group: 9). The cut-off value for the APACHE II score was 12 and the area under the curve value was 0.891. The Hosmer and Lemeshow C statistic x2 was 7.414 (p=0.387), indicating good calibration for APACHE II. Conclusion: The APACHE II score is useful at predicting the neurological prognosis of patients who have ingested glufosinate.

GQD layers for Energy-Down-shift layer on silicon solar cells by kinetic spraying method

  • Lee, Gyeong-Dong;Park, Myeong-Jin;Kim, Do-Yeon;Kim, Su-Min;Gang, Byeong-Jun;Kim, Seong-Tak;Kim, Hyeon-Ho;Lee, Hae-Seok;Gang, Yun-Muk;Yun, Seok-Gu;Hong, Byeong-Hui;Kim, Dong-Hwan
    • Proceedings of the Korean Vacuum Society Conference
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    • 2016.02a
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    • pp.422.1-422.1
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    • 2016
  • Graphene quantum dots (GQDs), a new kind of carbon-based photo luminescent nanomaterial from chemically modified graphene oxide (CMGO) or chemically modified graphene (CMG), has attracted extensive research attention in the last few years due to its outstanding chemical, optical and electrical properties. To further extended its potential applications as optoelectronic devices, solar cells, bio and bio-sensors and so on, intensive research efforts have been devoted to the CMG. However, the CMG, a suspension of aqueous, have problematic since they are prone to agglomeration after drying a solvent. In this study, we synthesized the GQDs from graphite and deposited on silicon substrate by kinetic spray. The photo luminescent properties of deposited GQD films were analyzed and compared with initial GQDs suspension. In addition, its carbon properties were investigated with GQDs solution properties. The properties of deposited GQD films by kinetic spray were similar to that of the GQDs suspension in water. We could provide a pathway for silicon-based silicon based device applications. Finally, the well-adjusted GQD films with photo luminescence effects will show Energy-Down-Shift layer effects on silicon solar cells. The GQD layers deposited at nozzle scan speeds of 40, 30, 20, and 10 mm/s were evaluated after they were used to fabricate crystalline-silicon solar cells; the results indicate that GQDs play an important role in increasing the optical absorptivity of the cells. The short-circuit current density (Jsc) was enhanced by about 2.94 % (0.9 mA/cm2) at 30 mm/s. Compared to a reference device without a GQD energy-down-shift layer, the PCE of p-type silicon solar cells was improved by 2.7% (0.4 percentage points).

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Establishment of an Antibacterial Yeast That Producing Bacteriocin Subpeptin JM4-A or Subpeptin JM4-B (박테리오신 Subpeptin JM4-A 혹은 Subpeptin JM4-B를 생산하는 항균 효모의 제작)

  • Lee, Ok-Hee;Jang, Min-Kung;Lee, Dong-Geun;Kim, In-Hae;Lee, Jae-Hwa;Ha, Jong-Myung;Ha, Bae-Jin;Ahn, Ik-Yong;Cho, Dong-In;Lee, Sang-Hyeon
    • Journal of Life Science
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    • v.18 no.2
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    • pp.287-290
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    • 2008
  • In order to obtain yeast cells producing a bacteriocin, Subpeptin JM4-A or Subpeptin JM4-B, the 48 bp oligonucleotides corresponding to Subpeptin JM4-A and Subpeptin JM4-B genes including codon for start and stop were chemically synthesized and cloned into pAUR123, an yeast expression vector. Transformed yeast cells exhibited growth inhibition of Bacillus subtilis, Escherichia coli and Pseudonomas aeruginosa. This result indicates that yeast cells producing Subpeptin JM4-A or Subpeptin JM4-B possess bacteriocidal properties against both Gram positive B. subtilis and Gram negative E. coli and P. aeruginosa cells. The recombinant yeast strains constructed in this study can be applied in the food preservative or. animal foodfeed.

The Effects of Teamwork by Servant Leadership on Job Attitudes (서번트 리더십에 따른 팀웍이 직무태도에 미치는 영향)

  • Ko, Ki-Chul;Jeon, Hae-Kyung;Cho, Yong-Bum
    • Culinary science and hospitality research
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    • v.18 no.1
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    • pp.91-103
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    • 2012
  • The study model was designed and the hypothesis was drawn based on precedent studies in order to analyze the effects of teamwork by servant leadership on job attitudes, aiming at full-time regular status employees and contract employees lower than the general manager position at special grade hotels in Busan. The SPSS WIN Version 15.0 integrated package for data process was used to verify the hypothesis through frequency analysis, reliability analysis, factorial analysis and regression analysis. As a result of study, the verification result for the effect of servant leadership on communication among the teamwork factors showed that forming sympathy and community and vision meaningfully affects communication; the verification result for the effect of servant leadership on interdependence among the teamwork factors showed that forming community, stewardship, vision factor meaningfully affects interdependence; The verification result for the effect of the teamwork factor on organizational commitment as a job attitude showed communication and interdependence meaningfully affect organizational commitment, one of job attitudes. Cousequently, the leaders in hotel organizations are expected to need a role of personnel management through organizational dependence and participatory management, to draw harmony and corporation among employees and build organizing systems, presenting a clear vision about the future to them.

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Functional Screening for Cell Death Suppressors and Development of Multiple Stress-Tolerant Plants

  • Moon, Hae-Jeong;Baek, Dong-Won;Lee, Ji-Young;Nam, Jae-Sung;Yun, Dae-Jin
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2003.04a
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    • pp.65-71
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    • 2003
  • Bax, a mammalian pro-apoptotic member of the Bcl-2 family, induces cell death when expressed in yeast. To investigate whether Bax expression can induce cell death in plant, we produced transgenic Arabidopsis plants that contained murine Bax cDNA under control of a glucocorticoid-inducible promoter. Transgenic plants treated with dexamethasone, a strong synthetic glucocorticoid, induced Bax accumulation and cell death, suggesting that some elements of cell death mechanism by Bax may be conserved among various organisms. Therefore, we developed novel yeast genetic system, and cloned several Plant Bax Inhibitors (PBIs). Here, we report the function of two PBIs in detail. PBI1 is ascorbate peroxidase (sAPX). Fluorescence method of dihydrorho-damine 123 oxidation revealed that expression of Bax in yeast cells generated reactive oxygen species (ROS), and which was greatly reduced by co-expression with sAPX. These results suggest that sAPX inhibits the generation of ROS by Bax, which in turn suppresses Baxinduced cell death in yeast. PBI2 encodes nucleoside diphosphate kinase (NDPK). ROS stress strongly induces the expression of the NDPK2 gene in Arabidopsis thaliana (AtNDPK2). Transgenic plants overexpressing AtNDPK2 have lower levels of ROS than wildtype plants. Mutants lacking AtNDPK2 had higher levels of ROS than wildtype. $H_2O_2$ treatment induced the phosphorylation of two endogenous proteins whose molecular weights suggested they are AtMPK3 and AtMPK6. In the absence of $H_2O_2$ treatment, phosphorylation of these proteins was slightly elevated in plants overexpressing AtNDPK2 but markedly decreased in the AtNDPK2 deletion mutant. Yeast two-hybrid and in vitro protein pull-down assays revealed that AtNDPK2 specifically interacts with AtMPK3 and AtMPK6. Furthermore, AtNDPK2 also enhances the MBP phosphorylation activity of AtMPK3 in vitro. Finally, constitutive overexpression of AtNDPK2 in Arabidopsis plants conferred an enhanced tolerance to multiple environmental stresses that elicit ROS accumulation in situ. Thus, AtNDPK2 appears to play a novel regulatory role in $H_2O_2$-mediated MAPK signaling in plants.

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Analysis of Cubesat Development Status in Korea (한국의 큐브위성 개발 현황 분석)

  • Han, Sanghyuck;Choi, Yeonju;Cho, Dong-Hyun;Choi, Won-Sub;Gong, Hyeon Cheol;Kim, Hae-Dong;Choi, Gi-Hyuk
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.45 no.11
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    • pp.975-988
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    • 2017
  • Since 2000, about 750 cubesats have been launched as of August 2017 and development and the launch of cubesat increased exponentially. Since standard of cubesat has been proposed in 1999, cubesats have grown considerably beyond the scope of education and technology verification to commercial use in the area of space exploration and earth observation, and the variety of cubesat mission and type has increased recently. In Korea, some universities and individuals have independently developed cubesats since 2000, and cubesat contests which were organized by KARI and sponsored by Ministry of Science and ICT from 2012 highly contributed to cubesat development in Korea. In addition, domestic institutes such as KARI, KASI started to develop cubesats for space science and exploration mission. Nineteen cubesats have been progressed or completed in development until now. In this paper, we present the technical trend and describe all cubesats in Korea.

Reviews on the Adaptation Strategy to Climate Change -Application to the Sea Level Rise- (기후변화 적응방안 연구 -해수면 상승을 중심으로-)

  • Cho Kwangwoo;Maeng Jun-Ho;Kim Hae-Dong;Oh Young Min;Kim Dong-Sun;Kim Mu Chan;Yoon Jong Hwui
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.10 no.2 s.21
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    • pp.81-88
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    • 2004
  • We review the adaptation strategies of the 21st climate change in an application to sea level rise. For the development of appropriate adaptation strategies on the coast vulnerable to the sea level rise, we have to consider the issues such as where to adapt, how to adapt, and when to adapt. The coastal target needed adaptation can be found by the evaluation of adaptive capacity of the coastal zone which requires the understanding of impacts and adaptive potential of the natural and socioeconomic systems in the coastal zone. Planned adaptation options to sea level rise can be classified into three generic approaches as managed retreat, accommodation, and protection In practice, the implementation of the options requires the analysis of land use, degree of vulnerability, cost and benefit, etc, and may be combination of the options rather than one approach. In terms of the response timing, the adaptation can be grouped as anticipatory and reactive ones. Generally it is more effective to consider both anticipatory and reactive adaptations at the same time for the impacts of future sea level rise. Due to the scientific uncertainty of climate change issues including sea level rise, the adaptation processes have to be designed to deal with a series of processes such as information md awareness establishment, planning and design implementation, and monitoring and evaluation in continuity and long-term period.

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Korean's Traditional Method to Increase the Amount of Breast Milk. (전통적 모유량 증가방법에 관한 연구)

  • Lee, Mi-La;Suh, Yeon-Ok;Cho, Jung-Ho;Kim, Tae-Im;Park, Young-Sook;Park, Song-Ja;Park, In-Sook;Park, Jong-Sook;Lee, Hae-Kyung;Yim, Hyun-Bin;Cho, Dong-Sook;Ju, Sook-Nam;Choi, Sang-Soon
    • 모자간호학회지
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    • v.3 no.2
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    • pp.142-152
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    • 1993
  • In recent days, most of mothers prefer bottle feeding to breast feeding. Even mothers who started with breast feeding, change to bottle feeding in a short period. Many factors were reported causing the trend, but a significant influencing latter was revealed the mothers' perception that their breast milk wasn't enough for their babies. The purpose of this study were to identify how mothers of 30 years ago kept breastfeeding longer period for their child, and what were the diet they used in order to keep adequate breast milk secretion. The subjects of this study were 95 women who are over 60 years or older. Data were gathered by 13 authors by interview using structured questionnare. There were 16 questions related to subject's demographic informations and the specific recipe which they used, and 7 questions related to breast feeding techniques they used. Data were analyzed by SPSS/PC and content analysis. Results were as follows. 1. The subjects reflected that their milk secretion was enough to feed their tables. 2. More than half of the subject started breast feeding on the 3rd day after delivery and had continued breast feeding until they were pregnant again. 3. The subjects tried to eat as much rice and seaweed (MiYuk) soup as possible and didn't take any other specific diet during the breast feeding period. 4. The subjects didn't pay specific attention to the breast, general health. emotion, home environment. The only thing they did was being careful not to press breast when not feed. 5. Many subjects perceived that breast feeding made them healthy, and only 7% of subjects responded that they had some health problem during the breast feeding period.

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Clinical Observation and Treatment of Fracture-Dislocation of Talus (거골 골절 및 탈구의 임상적 고찰)

  • Lee, Dong-Chul;Kim, Se-Dong;Jung, Hae-Hoon
    • Journal of Yeungnam Medical Science
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    • v.9 no.2
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    • pp.302-311
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    • 1992
  • Talus is a important structure of the ankle joint and its function is critical for ambulation and weight bearing. The talus fracture is rare, but the complications of fracture and dislocation are serious and resulting in avascular necrosis, osteoarthritis. So its treatment is carefully considered at initial status. Authors reviewed 11 cases of fracture and dislocation of the talus treated at Yeungnam university hospital from 1984 to 1991. The longest follow up was 8 years and shortest, 1 year. The results were as follows. 1. There were all males, the average age was 30 years old. 2. The most common cause was fall down(8 cases), and next traffic accident(2cases), sports injury(1 case). 3. According to Marti-Weber classification, 1 cases was type I, 1 in type II, 4 in type III and 5 in type IV. 4. The method of treatment were open reduction and internal fixation in 6 cases, the others were closed reduction in 5 cases. 5. Final results(by Hawkins grading system) were as follows, 3 cases were excellent, 4 cases were good, 1 case was fair and 3 cases were poor. 6. Complications were AVN in 2 cases, degenerative arthritis in 8 cases, malunion in 1 case. 7. The range of motion of the ankle joint was relatively preserved(74%), but in the subtalar joint it was decreased(43%).

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Efficacy of a Training Program for Long-Term Disease-Free Cancer Survivors as Health Partners: A Randomized Controlled Trial in Korea

  • Yun, Young Ho;Lee, Myung Kyung;Bae, Yeonmin;Shon, Eun-Jung;Shin, Bo-Ram;Ko, Hyonsook;Lee, Eun Sook;Noh, Dong-Young;Lim, Jae-Young;Kim, Sung;Kim, Si-Young;Cho, Chi-Heum;Jung, Kyung Hae;Chun, Mison;Lee, Soon Nam;Park, Kyong Hwa;Chang, Yoon Jung
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7229-7235
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    • 2013
  • Background: To determine whether the Health Partner Program is effective in training long-term cancer survivors to be health coaches. Materials and Methods: We randomly assigned cancer survivors who were selected through a rigorous screening process to either the Health Partner Program or the waiting-list control group. The program consisted of 8 weeks of training in health management, leadership, and coaching. At baseline, 8, and 16 weeks, we measured primary outcomes using the Seven Habit Profile (SHP), the Korean Leadership Coaching Competency Inventory (KCCI), Ed Diner's Satisfaction with Life Scale (SWLS), and the Posttraumatic Growth inventory (PTGI) and secondary outcomes using the Hospital Anxiety and Depression Scale (HADS), the Impact of Event Scale-Revised (IES-R), and the Medical Outcomes Study (MOS) short form 36-item questionnaire (SF-36). Results: We recruited 70 subjects and randomly assigned 34 to the intervention group. The Sharpen the Saw habit of the SHP increased significantly more in intervention group than in the control group (p=0.049), as did most PTGI factors. The intervention group also showed a significantly greater enhancement of vitality (p=0.015) and mental health (p=0.049) SF-36 scores but no improvement in KCCI, SWLS, HADS, or IES-R scores. The intervention group also showed a greater clinically meaningful improvement in the "Think Win-Win" of SHP (p=0.043) and in the personal strength score (p=0.025) and total score (p=0.015) of the PTGI. Conclusions: Long-term cancer survivors can benefit from the Health Partner Program to become health coaches.