• Earthquakes and Structures
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• 제10권5호
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• pp.989-1012
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• 2016

The structural dynamic behavior and yield strength considering both ductility and strain rate effects are analyzed in this article. For the single-degree-of-freedom (SDOF) system, the relationship between the relative velocity and the strain rate response is deduced and the strain rate spectrum is presented. The ductility factor can be incorporated into the strain rate spectrum conveniently based on the constant-ductility velocity response spectrum. With the application of strain rate spectrum, it is convenient to consider the ductility and strain rate effects in engineering practice. The modal combination method, i.e., square root of the sum of the squares (SRSS) method, is employed to calculate the maximum strain rate of the elastoplastic multiple-degree-of-freedom (MDOF) system under uniform excitation. Considering the spatially varying ground motions, a new response spectrum method is developed by incorporating the ductility factor and strain rate into the conventional response spectrum method. In order to further analyze the effects of strain rate and ductility on structural dynamic behavior and yield strength, the cantilever beam (one-dimensional) and the triangular element (two-dimensional) are taken as numerical examples to calculate their seismic responses in time domain. Numerical results show that the permanent displacements with and without considering the strain rate effect are significantly different from each other. It is not only necessary in theory but also significant in engineering practice to take the ductility and strain rate effects into consideration.

• Bulletin of the Korean Chemical Society
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• 제34권12호
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• pp.3665-3670
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• 2013

The R3V6 peptide includes a hydrophilic arginine stretch and a hydrophobic valine stretch. In previous studies, the R3V6 peptide was evaluated as a gene carrier and was found to have low cytotoxicity. However, the transfection efficiency of R3V6 was lower than that of poly-L-lysine (PLL) in N2A neuroblastoma cells. In this study, the transfection efficiency of R3V6 was improved in combination with high mobility group box 1A domain (HMGA). HMGA is originated from the nuclear protein and has many positively-charged amino acids. Therefore, HMGA binds to DNA via charge interaction. In addition, HMGA has a nuclear localization signal peptide and may increase the delivery efficiency of DNA into the nucleus. The ternary complex with HMGA, R3V6, and DNA was prepared and evaluated as a gene carrier. First, the HMGA/DNA complex was prepared with a negative surface charge. Then, R3V6 was added to the complex to coat the negative charges of the HMGA/DNA complex, forming the ternary complex of HMGA, R3V6, and DNA. A physical characterization study showed that the ternary complex was more stable than the PLL/DNA complex. The HMGA/R3V6/DNA complex had a higher transfection efficiency than the PLL/DNA, HMGA/DNA, or R3V6/DNA complexes in N2A cells. Furthermore, the HMGA/R3V6/DNA complex was not toxic to cells. Therefore, the HMGA/R3V6/DNA complex may be a useful gene delivery carrier.

• 한국강구조학회 논문집
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• 제21권4호
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• pp.361-373
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• 2009

유전자 알고리즘을 이용한 닐센아치교의 최적설계기법을 이 논문에서 제시하였다. 설계 매개변수로는 닐센아치교의 아치-라이즈비와 강중비에 대해서 최적화기법을 적용하여 각각의 거동을 분석하고, 적정성을 평가하여 최적의 매개변수 값을 결정하였다. 매개변수의 결정은 구조물의 안전성과 사용성 그리고 경제성에 중요한 설계인자로서 정형화가 요구된다. 이를 위해 최적화 기법으로 전역 최적해 탐색능력이 우수한 유전자 알고리즘을 사용하였으며, 설계 목적함수로는 구조물의 총 중량을 사용하였고, 제약조건으로는 변위, 응력, 시공성 제약조건을 두었다. 구조해석은 미소변위이론에 의한 탄성해석을 수행하여 유전자 알고리즘과 조합하여 병렬연산으로 수행시간을 단축시켰다. 이 연구에서 개발된 최적설계기법을 사용하여 최적의 아치-라이즈비와 강중비, 최적설계영역을 제시 하였으며 실무에 적용할 수 있도록 하였다.

• 한국언어정보학회:학술대회논문집
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• 한국언어정보학회 2001년도 학술대회 논문집
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• pp.199-225
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• 2001

The main goal of this paper is to investigate and compare English, German and Korean non-head-bound-intensifiers such as English ‘x-self’, German ‘selbst’, and Korean ‘susulo, casin’. That is, this paper is mainly concerned with the semantic domain where the respective contributions of the expressions in question overlap. The phenomenon under discussion with the label “intensifiers” is regarded as universal, which provides the ground of the comparative/contrastive or semi-cross-linguistic study of this paper. Not only the semantic concept of intensification by these expressions but also the combination of grammatical features or syntactic behaviours thereof seem to have highly invariant common denominators among the wide varieties of languages, even if they come from apparently different language families. In comparing English, German and Korean intensifiers, this paper is interested in the more general features of the expressions in question rather than some language-specific idiocyncracies. Intensifiers work similarly not only in English and German, but also in Korean. Each of three languages under investigation provides some sort of a safegard against confusing instances and misleading judgements on the issues under discussion. Morphologically, however, English expressions in question agree with their rele-vant NP in number, gender and person. Whereas German and Korean counterparts do not have such specific morphological properties. Intensifiers in their non-head-bound-use are subject-oriented, just as in their head-bound use. Non-head-bound-intensifiers differ from head-bound-intensifiers mostly in their syntactic behaviours or distributional properties, whereas they share the semantic domain “intensification” regarding relevant subject-NP. They introduce an ordering and distinguish center and periphery, and ‘self-involvement (directness of involvement)’seems a additional possible characterisation of the relevant dimension of these intensifiers in common. An assertion of identity also can be reg

• 한국지반환경공학회 논문집
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• 제15권4호
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• pp.13-27
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• 2014

Catchments soil erosion, one of the most serious problems in the mountainous environment of the world, consists of a complex phenomenon involving the detachment of individual soil particles from the soil mass and their transport, storage and overland flow of rainfall, and infiltration. Sediment size distribution during erosion processes appear to depend on many factors such as rainfall characteristics, vegetation cover, hydraulic flow, soil properties and slope. This study involved laboratory flume experiments carried out under simulated rainfall in a 3.0 m long ${\times}$ 0.8 m wide ${\times}$ 0.7 m deep flume, set at $17^{\circ}$ slope. Five experimental cases, consisting of twelve experiments using three different sediments with two different rainfall conditions, are reported. The experiments consisted of detailed observations of particle size distribution of the out-flow sediment. Sediment water mixture out-flow hydrograph and sediment mass out-flow rate over time, moisture profiles at different points within the soil domain, and seepage outflow were also reported. Moisture profiles, seepage outflow, and movement of overland flow were clearly found to be controlled by water retention function and hydraulic function of the soil. The difference of grain size distribution of original soil bed and the out-flow sediment was found to be insignificant in the cases of uniform sediment used experiments. However, in the cases of non-uniform sediment used experiments the outflow sediment was found to be coarser than the original soil domain. The results indicated that the sediment transport mechanism is the combination of particle segregation, suspension/saltation and rolling along the travel distance.

• 복식
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• 제54권2호
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• pp.105-119
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• 2004

Cultural hybridization and global cross-fertilization, begun since the 1990s, mean the hybrid mixture of the low-class popular arts and the high-class fine arts and have found expression in intertextuality by means of the thinking system of de-constructuralist post-modernism. This study was intended to investigate the artistic intertextuality between fashion and art frontiere, especially between such fields as 'animation', 'music', and 'performing arts' and 'fashion', which shows the greatest characteristic of the phenomenon that the non-mainstream culture flows into the mainstream culture. It also aimed to investigate the intertextuality between 'technology' and 'fashion' as the delivery room of the youth culture and copycat culture due to the benefit of technologies since the 20th-century digital revolution. Animation as the neo-pop art with the popular code coming to the forefront in the 21th century integrated high-class fashion and low-class fashion into one through the combination of fashion and humor, and the musical element referring to the social difference of the cultural field and the social strata is becoming the 21th-century fashion icon through its fusion with the pictorial tendency along with the leisure-time life of the non-mainstream strata. In terms of intertextuality in performing arts, fashion style performs an important role in the presentation of performing arts and since the de-construction of the fin-de-ciecle form and its fusion with media have taken place, fashion works become and element of the origin that has an influence on a series of film, dance, dramatic elements and the like. The paradigm of technology made it socially and culturally possible to achieve the architecture of clothing system necessary for fashionable technical clothing by allowing the possibility of imitation, the function of technology to form popular culture. The intertextual tendency in the 21th-century fashion began from the de-constructive phenomenon of existing norms and now takes the multicultural character of surpassing a certain domain or concept. And it positions itself as the total art of spearheading the low-class culture and the non-mainstream culture as the hybrid domain of mainstream and non-mainstream cultures or high-class and low-class cultures.

• 한국통신학회논문지
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• 제38A권3호
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• pp.268-276
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• 2013

본 연구에서는 Heterogeneous Network에서의 간섭제어에 관한 기술 동향을 살펴보고, 간섭 제어 기술 중 3GPP release 10에서의 주요 기술 enhanced Inter-Cell Interference Coordination (enhanced ICIC, eICIC)을 택하여 성능을 분석해 보았다. eICIC기술 중 시간영역에서의 간섭 제어인 Almost Blank Subframe (ABS)와 Cell Range Expansion (CRE) 기술에 의한 성능을 분석하였다. Heterogeneous Network에서 macrocell과 femtocell 간의 간섭 제어를 적절히 하기 위해서는 ABS기술과 CRE 기술 간의 조합이 중요할 것으로 보인다. Heterogeneous Network의 전체 성능 평가는 정량적으로는 분석되기 어려워 system level simulation에 의해서 평가하였다. 본 연구에서는 SLS 방식으로 다양한 환경에 대한 성능을 분석함으로써 Heterogeneous Network 운영에 있어 각각의 요소가 미치는 영향을 파악할 수 있도록 하였으며, Heterogeneous Network에서의 ABS와 CRE의 결합에 의한 효과를 분석하였다.

• 한국학교수학회논문집
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• 제16권2호
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• pp.363-381
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• 2013

수학학습양식의 4가지 구성요인은 인지적 학습양식에서 정보인식 유형과 정보처리 유형이고 정의적 학습양식에서 수학학습에 대한 태도와 수학학습 환경에 대한 태도이다. 각 요인은 대립하는 두 개의 양식으로 구분되며 정보인식 유형은 시각적 양식과 언어적 양식으로, 정보처리 유형은 전체적 양식과 분석적 양식으로, 수학학습에 대한 태도는 권위목표형과 실용오락형으로, 수학학습 환경에 대한 태도는 내부지향형과 외부지향형으로 나눌 수 있다. 총 8가지의 수학학습양식의 조합에 의하여 16가지 수학학습유형으로 분류된다. 본 연구는 중학교 3학년 학생들을 대상으로 수학학습양식과 수학학습유형에 대한 선호도를 분석하여 학습자의 개인차를 인식하고 효과적인 수업전략을 모색하는데 시사점을 제공하고자 한다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2005년도 가을 학술발표논문집 Vol.32 No.2 (2)
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• pp.235-237
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• 2005

도메인 조합 기반의 단백질-단백질 상호작용 예측 기법(DCPPIP)은 효모 단백질에 대하여 뛰어난 정확도를 보여준다. 그러나 다른 종에서의 예측 정확도 및 기법의 유효성은 아직까지 검증되지 않고 있다. 본 논문에서는, 초파리 및 인간 단백질을 이용한 예측 정확도 검증 및 이종간의 상호작용 예측 실험의 결과를 기술한다. 초파리와 인간 단백질의 실험에서는 각각 10,351개와 2,345개의 상호작용 단백질 쌍이 사용되었다. 초파리와 인간의 상호작용 단백질 쌍 중 $80\%$와 $20\%$를 각각 학습집단 및 실험집단으로 사용하였으며. 상호작용이 없는 단백질 쌍의 학습집단은 1배에서 5배까지 변화시키면서 예측 정확도를 관찰하였다. 정확도는 실험집단 중 학습집단과 도메인이 완전히 혹은 부분적으로 겹치는 쌍들에 대하여 계산하였다. 이 결과 초파리에서는 약 $77\%$의 민감도와 $92\%$의 특이도가 확인되었고 인간 단백질에 대하여는 약 $96\%$의 민감도와 $95\%$의 특이도를 보여주었다. 이종간의 상호작용 예측 실험은 효모, 초파리, 효모+초파리에 해당하는 학습집단 각각을 바탕으로 Human, Mouse, H. pylori, E. coli, C. elegans 등의 단백질 상호작용 예측을 수행하였다. 실험 결과 학습집단의 도메인이 실험집단의 도메인과 많이 겹칠 수륵 높은 정확도를 보여주었으며, 도메인 집단간의 유사도를 나타내기 위해 고안한 Domain Overlapping Rate(DOR)는 상호작용 예측 정확도의 중요한 요소임을 찾아 내었다.

• 한국가축번식학회지
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• 제25권4호
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• pp.381-388
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• 2001

본 연구는 돼지에서 성장호르몬과 결합되는 부위에 변이를 유도하여 결합력이 향상된 성장호르몬 결합단백질을 획득하기 위하여 수행되었다. 돼지의 지방으로부터 얻은 성장호르몬 수용체 RNA 내 성장호르몬 결합단백질 부분을 756 bp의 cDNA로 전향하고 클로닝한 후 site-directed mutagenesis 방법을 이용하여 26과 122번째 아미노산을 변이시켰다. 26번째 아미노산은 성장 호르몬과의 결합에 관련이 있다고 알려져 있는 돼지 성장호르몬 수용체 외막에 존재하는 다섯 군데의 N-linked glycosylation 부위와 가까이 위치한 부분이고, 122번째 아미노산은 소에서의 결합부위로 알려져 있다. 이렇게 변이를 유도한 성장호르몬 결합 단백질을 pET-32(c) 발현벡터에 삽입시키고 과발현시켰고 이를 정제하여 30 kDa의 변이를 유도한 성장호르몬 결합 단백질을 얻었다. 이러한 방법으로 성장호르몬 결합 단백질을 성장기에 있는 세포나 동물에 주입한다면 보다 향상된 성장을 볼 수 있을 것으로 사료된다.