• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.18 no.3
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• pp.361-367
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• 2008

Many trials have been used to model room impulse responses, all attempting to provide efficient representations of room acoustics. The traditional model designs for room impulse response seem to fail in accuracy, controllability, or computational efficiency. In the time domain, room impulse responses are generally considered as combination of the three Parts having different acoustic characteristics, initial time delay, early reflection, and late reverberation. This paper introduces new learning hybrid model for room impulse responses. In this proposed model, those three parts are modeled using different models with learning algorithms that determine the boundary of each model in the hybrid model. By the simulation with measured room impulse responses, the performance of proposed model shows the best efficiency in views of computational burden and modeling error.

• Journal of Microbiology
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• v.42 no.1
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• pp.32-36
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• 2004

We have previously isolated three synthetic lethal mutants from Schizosaccharomyces pombe in order to identify mutations in the genes that are functionally linked to spmex67 with respect to mRNA export. A novel rsm1 gene was isolated by complementation of the growth defect in one of the synthetic lethal mutants, SLMex1. The rsml gene contains no introns and encodes a 296 amino-add-long protein with the RING finger domain, a C3HC4 in the N-terminal half. The Δrsm1 null mutant is viable, but it showed a slight poly(A)$\^$＋/ RNA accumulation in the nucleus. Also, the combination of Δrsm1 and Δspmex67 mutations confers synthetic lethality that is accompanied by the severe poly(A)$\^$＋/ RNA export defect. These results suggest that rsm1 is involved in mRNA export from the nucleus.

• Mycobiology
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• v.43 no.2
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• pp.150-156
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• 2015

2',4'-Dihydroxychalcone (2',4'-DHC) was identified from a heat shock protein 90 (Hsp90)-targeting library as a compound with Hsp90 inhibitory and antifungal effects. In the presence of 2',4'-DHC ($8{\mu}g/mL$), radial growth of Aspergillus fumigatus was inhibited 20% compared to the control, and green pigmentation was completely blocked. The expression of the conidiation-associated genes abaA, brlA, and wetA was significantly decreased (approximately 3- to 5-fold) by treatment with 2',4'-DHC. The expression of calcineurin signaling components, cnaA and crzA, was also significantly reduced. The inhibitory effects of 2',4'-DHC on metabolic activity and mycelial growth were significantly enhanced by combination treatment with itraconazole and caspofungin. Docking studies indicated that 2',4'-DHC bind to the ATPase domain of Hsp90. These results suggest that 2',4'-DHC act as an Hsp90-calcinurin pathway inhibitor.

• Korea-Australia Rheology Journal
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• v.16 no.1
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• pp.1-15
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• 2004

The computation of viscoelastic flow using neural networks and stochastic simulation (CVFNNSS) is developed from the point of view of Eulerian CONNFFESSIT (calculation of non-Newtonian flows: finite elements and stochastic simulation techniques). The present method is based on the combination of radial basis function networks (RBFNs) and Brownian configuration fields (BCFs) where the stress is computed from an ensemble of continuous configuration fields instead of convecting discrete particles, and the velocity field is determined by solving the conservation equations for mass and momentum with a finite point method based on RBFNs. The method does not require any kind of element-type discretisation of the analysis domain. The method is verified and its capability is demonstrated with the start-up planar Couette flow, the Poiseuille flow and the lid driven cavity flow of Hookean and FENE model materials.

• International Journal of Aeronautical and Space Sciences
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• v.15 no.1
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• pp.63-73
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• 2014

For robust stability analysis of parameters uncertainty missiles, the traditional frequency domain method can only analyze each respective channel at several interval points within uncertain parameter space. Discontinuous calculation and couplings between channels will lead to inaccurate analysis results. A method based on the ${\nu}$-gap metric is proposed, which is able to comprehensively evaluate the robust stability of missiles with uncertain parameters; and then a genetic-simulated annealing hybrid optimization algorithm, which has global and local searching ability, is used to search for a parameters combination that leads to the worst stability within the space of uncertain parameters. Finally, the proposed method is used to analyze the robust stability of a re-entry missile with uncertain parameters; the results verify the feasibility and accuracy of the method.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.58 no.8
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• pp.1633-1637
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• 2009

We propose a new technique for sidelobe suppression in orthogonal frequency division multiplexing (OFDM) systems. Sidelobe suppression is an essential technique to design OFDM based overlay system. The proposed technique is based on the combination of the multiple choice sequence (MCS) with the conventional windowing of OFDM signal in time domain. The MCS is choosing the one sequence which has lowest power in sidelobes from the produced set of sequences. The main advantage of proposed technique is that it fully utilizes the available bandwidth to transmit data. Simulation results show that by combining MCS with conventional windowing technique, the sidelobes in OFDM system can be significantly reduced

• Journal of Mechanical Science and Technology
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• v.20 no.7
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• pp.950-960
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• 2006

An output time delay always exists in practical systems. Analysis of the delay phenomenon in a continuous-time domain is sophisticated. It is appropriate to obtain its corresponding discrete-time model for implementation via a digital computer. A new method for the discretization of nonlinear systems using Taylor series expansion and the zero-order hold assumption is proposed in this paper. This method is applied to the sampled-data representation of a nonlinear system with a constant output time-delay. In particular, the effect of the time-discretization method on key properties of nonlinear control systems, such as equilibrium properties and asymptotic stability, is examined. In addition, 'hybrid' discretization schemes resulting from a combination of the 'scaling and squaring' technique with the Taylor method are also proposed, especially under conditions of very low sampling rates. A performance of the proposed method is evaluated using two nonlinear systems with time-delay output.

• Earthquakes and Structures
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• v.7 no.6
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• pp.895-908
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• 2014

The main objective of critical excitation methods is to reveal the worst possible response of structures. This goal is accomplished by considering the uncertainties of ground motion, which is subjected to the appropriate constraints, such as earthquake power and intensity limit. The concentration of this current study is on the theoretical optimization aspect, as is the case with the majority of conventional critical excitation methods. However, these previous studies on critical excitation lead to a discontinuous power spectral density (PSD). This paper introduces some critical excitations which contain proper continuity in frequency domain. The main idea for generating such continuous excitations stems from the combination of two continuous functions. On the other hand, in order to provide a non-stationary model, this paper attempts to present an appropriate envelope function, which unlike the previous envelope functions, can properly cover the natural earthquakes' accelerograms based on multi-peak conditions. Finally, the proposed method is developed into the multiple-degree-of-freedom (M.D.O.F) structures.

• Ocean Systems Engineering
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• v.3 no.2
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• pp.149-165
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• 2013

Tension leg platforms (TLP's) are highly nonlinear due to large structural displacements and fluid motion-structure interaction. Therefore, the nonlinear dynamic response of TLP's under hydrodynamic wave loading is necessary to determine their deformations and dynamic characteristics. In this paper, a numerical study using modified Morison Equation was carried out in the time domain to investigate the influence of nonlinearities due to hydrodynamic forces and the coupling effect between all degrees of freedom on the dynamic behavior of a TLP. The stiffness of the TLP was derived from a combination of hydrostatic restoring forces and restoring forces due to cables and the nonlinear equations of motion were solved utilizing Newmark's beta integration scheme. The effect of wave characteristics was considered.

• The Korean Journal of Applied Statistics
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• v.23 no.2
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• pp.249-261
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• 2010

Long-term forecasting of seasonal time series is critical in many applications such as planning business strategies and resolving possible problems of a business company. Unlike the traditional approach that depends solely on dynamic models, Li and Hinich (2002) introduced a combination of stochastic dynamic modeling with filter bank approach for forecasting seasonal patterns using highly coherent(High-C) waveforms. We modify the filter selection and forecasting procedure on wavelet domain to be more feasible and compare the resulting predictor with one that obtained from the wavelet variance estimation method. An improvement over other seasonal pattern extraction and forecasting methods based on such as wavelet scalogram, Holt-Winters, and seasonal autoregressive integrated moving average(SARIMA) is shown in terms of the prediction error. The performance of the proposed method is illustrated by a simulation study and an application to the real stock price data.