• 한국임상수의학회지
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• 제23권3호
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• pp.349-354
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• 2006

5개월간의 일시적인 기절현상(syncope)을 주증상으로 내원한 9개월령의 1.97kg 미니어쳐 핀셔견에서 호흡곤란, 심초음파에서의 현저한 심실/심방의 확장, 전반적인 심비대, 약한 맥박, 폐수종 등 DCM의 진단 지표를 기준을 통해 확장성 심근병을 진단하였다. 본 증례에서 심초음파 검사는 심장의 확장과 심무력을 유발하는 다른 심장 질환을 배제하고 DCM을 확진 하는데 중요한 역할을 하였다. 치료를 위해 산소공급과, nitroglycerine patch, furosemide, pimobendan, benazepril, potassium gluconate gel을 19일간 처방한 결과 초기 내원시 보였던 대부분의 임상증상이 개선되었다.

• Asian-Australasian Journal of Animal Sciences
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• 제18권11호
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• pp.1623-1627
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• 2005

Heavy metal pollution has become a serious health concern in recent years. Dogs are a very good indicator of the pollution load on the environment. They share people's environment and are exposed to the action of the same pollutants. This study estimated the heavy metal contents in the serum of dogs in domestic districts, and assessed the age, sex, feeding habits, living area, breeding environment and smoking habit of the owners. The findings suggest that dogs can be used to monitor the environmental quality of heavy metals. The mean concentrations of heavy metals in the dog serum from 204 samples (108 male and 96 female) were 0.22${\pm}$0.01 $\mu$g/ml, 0.24${\pm}$0.04 $\mu$g/ml, 0.61${\pm}$0.08 $\mu$g/ml, and 0.50${\pm}$0.06 $\mu$g/ml (for Cd, Hg, Pb, and Cr), respectively. Concentrations of Pb, Cd, Hg, and Cr in the dog serum were higher in Yeongnam including Ulsan, and Seoul higher than those of Chungchong and Honam, especially Pb concentration, which was significantly higher (p<0.01). Concentrations of Cd, Hg, Pb, and Cr in serum, were increased by age (p<0.05). When commercial pet food was provided to dogs, Cd and Cr concentrations were significantly higher in dog serum than dogs fed a human diet (p<0.01 in Cd and p<0.05 in Cr). Heavy metal concentrations of dogs owned by smoking owners, were higher than non-smoking owners although there was no significant difference.

• Parasites, Hosts and Diseases
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• 제54권1호
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• pp.55-60
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• 2016

The aim of the present study is to determine the characteristics of genotype and phenotype of Echinococcus granulosus derived from wild sheep and to compare them with the strains of E. granulosus sensu stricto (sheep-dog) and E. granulosus camel strain (camel-dog) in Iran. In Khojir National Park, near Tehran, Iran, a fertile hydatid cyst was recently found in the liver of a dead wild sheep (Ovis orientalis). The number of protoscolices (n=6,000) proved enough for an experimental infection in a dog. The characteristics of large and small hooks of metacestode were statistically determined as the sensu stricto strain but not the camel strain (P=0.5). To determine E. granulosus genotype, 20 adult worms of this type were collected from the infected dog. The second internal transcribed spacer (ITS2) of the nuclear ribosomal DNA (rDNA) and cytochrome c oxidase 1 subunit (COX1) of the mitochondrial DNA were amplified from individual adult worm by PCR. Subsequently, the PCR product was sequenced by Sanger method. The lengths of ITS2 and COX1 sequences were 378 and 857 bp, respectively, for all the sequenced samples. The amplified DNA sequences from both ribosomal and mitochondrial genes were highly similar (99% and 98%, respectively) to that of the ovine strain in the GenBank database. The results of the present study indicate that the morpho-molecular features and characteristics of E. granulosus in the Iranian wild sheep are the same as those of the sheep-dog E. granulosus sensu stricto strain.

• 한국임상수의학회지
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• 제30권6호
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• pp.496-498
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• 2013

본 증례는 충남대학교 수의과대학 부속동물병원에 내원한 심장사상충에 중감염된 2세, 암컷의 진도견에서 혈장 NT-pro BNP농도를 측정하였다. 심장사상충 감염은 신체검사, 혈액검사, ELISA 키트검사 및 영상진단검사 등으로 진단하였다. 본 증례 진도견의 혈장 NT-pro BNP농도는 심장사상충에 감염되지 않고, 다른 질병도 없는 5마리(모두2세, 모두 암컷)의 정상견과 비교하였을 때, 상대적으로 매우 높은 수치를 나타내었다 (정상견 평균: 373 pmol/L, 본 증례: 2,950 pmol/L). 본 연구는 우리가 아는 한 심장사상충에 감염된 진도견에서 혈장 NT-pro BNP농도를 측정하여 보고한 최초의 증례보고이다.

• 한국임상수의학회지
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• 제31권4호
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• pp.325-328
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• 2014

A 8-month-old female Maltese dog was presented with a history of heart murmur. In physical examination, grade 4/6 systolic murmur heard at the left heart base. Electrocardiography showed sinus arrhythmia, right axis deviation, deep S wave and splintered QRS complex. Thoracic radiography revealed enlarged right side heart and bulging of the main pulmonary artery. Echocardiography showed mild hypertrophy of right ventricle, a supravalvular stenosis, marked post-stenotic dilation of the main pulmonary artery and a moderately increased pulmonary arterial velocity through the stenotic area (4.4 m/s, pressure gradient of 78.7 mmHg). The dog was diagnosed with supravalvular pulmonic stenosis based on the diagnostic imaging findings. Medical management using ${\beta}1$-blocker and ACE inhibitor was started in this dog and this is first case report described diagnostic characteristic features of supravalvular pulmonic stenosis in korea.

• 대한수의학회지
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• 제48권3호
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• pp.311-316
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• 2008

A 7-year-old female Shih Tzu dog with lots of masses in the whole mammary gland was presented to the surgery department of the Veterinary Teaching Hospital in the Cheju National University. After surgical excision, all mammary samples were referred to Pathology Department of Veterinary Medicine. Grossly, masses were measuring up to $6.5{\times}4{\times}1cm$ and on cut surface of masses in right 1st, 3rd, 4th, 5th and left 1st, 3rd, 4th, 5th mammary masses were well delineated and firm, sulphur yellow, solid round to oval shape. Microscopically, most neoplastic sweat glands were severely proliferated in dermis and subcutis. Most tubules were lined by round to oval shaped epithelium with eosinophilic cytoplasm, hyperchromatic nuclei with high mitotic figures and severe central necrosis. The neoplastic epithelium also had PAS-positive diastase-resistant cytoplasmic granules, but negative with Perls iron stain. The left 2nd mass was well delineated, and had several dark brown areas and yellowish white glittered areas. Mass was well circumscribed with dense connective tissue. Neoplastic areas contained irregular sized mammary gland with papillary grown luminal epithelial cells in single or double cells layer with mitotic figures and small amounts of proliferated myoepithelial cells. Proliferated myoepithelial cells also produced slightly basophilic mucinous materials. Based on the gross, histopathologic and special staining characteristics, this dog was diagnosed as 90% of apocrine sweat gland aenocarcinoma and 10% mammary. complex adenomas in mammary masses. In our best knowledge, this is the first report for concurrent occurrence of apocrine sweat gland adenocarcinoma and mammary gland complex adenoma in mammary masses of the same dog.

• Parasites, Hosts and Diseases
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• 제47권2호
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• pp.189-191
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• 2009

Four feral cats and a raccoon dog purchased from a local collector on Aphaedo Island, Shinan-gun, where human Gymnophalloides seoi infections are known to be prevalent, were examined for their intestinal helminth parasites. From 2 of 4 cats, a total of 310 adult G. seoi specimens were recovered, Other helminths detected in cats included Heterophyes nocens (1,527 specimens), Pygidiopsis summa (131), Stictodora fuscata (4), Acanthotrema felis (2), Spirometra erinacei (15), toxocarids (4), and a hookworm (1). A raccoon dog was found to be infected with a species of echinostome (55), hook-worms (7), toxocarids (3), P. summa (3), and S. erinacei (1). No G. seoi was found in the raccoon dog. The results indicate that feral cats and raccoon dogs on Aphaedo are natural definitive hosts for intestinal trematodes and cestodes, including G. seoi, H. nocens, and S. erinacei, It has been first confirmed that cats, a mammalian species other than humans, play the role of a natural definitive host for G. seoi on Aphaedo Island.

• 한국동물위생학회지
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• 제39권2호
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• pp.69-74
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• 2016

Jeju Dogs have high academic value due to their unique characteristics and conditions, but they have received little attention in the research field. This paper attempts to secure fundamental data to clarify the general characteristics of Jeju Dogs. For this purpose, an inspection of the basic body shape was performed to establish the shape and breed standards. Jeju Dogs were also exposed to 12 behavior tests to check their distinct character categories and an objective ethogram was built on each of the character categories to conduct a behavior analysis. The body shape of 34 clinically healthy Jeju Dogs aged 18 months or older was inspected using ten divided parts. For the behavior analysis, 10 Jeju Dogs were examined. A variety of behavioral variables were recorded based on 12 behavior tests that were categorized into four characters: sociality, aggressiveness, anxiety and submissiveness. The results of the body shape inspection indicated that most of the male dogs' parts had larger measured values than the female dogs' parts. The behavior analysis results revealed that the Jeju Dog displays excellent qualities such as submissiveness, reliability and fidelity and, hence, it is believed that this breed of dog is very appropriate for most duties and has the potential to be a household dog or working dog.

• 한국임상수의학회지
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• 제26권6호
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• pp.603-605
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• 2009

7연령의 암컷 미니어처 슈나우저견이 갑작스런 발작과 근육 떨림 증상을 주증으로 내원하였다. 내원 당시 발열과 헐떡임이 두드러졌으며, 신체검사 상에서 현저한 앞다리 근육 강직증상, 근육부분수축과 뻣뻣한 걸음걸이가 관찰되었다. 실험실 검사에서 심각한 저칼슘혈증과 함께 고인혈증이 특징적으로 관찰되었다. 이와 더불어 관찰된 낮은 농도의 부갑상선 호르몬과 이온화된 칼슘농도, 뇨중 칼슘과 인의 배설 량 측정을 통하여 원발성 부갑상선기능저하증이 진단되었다. 이 환축은 10% 글루콘산칼슘 투여를 통한 초기 치료에 반응이 좋았으며, 비타민 D 유사체와 칼슘 보조제를 통한 유지 치료에 의해 잘 관리 되고 있다. 부작용으로 일시적인 고인혈증이 나타났으나, 이 역시 경구용인 흡착제인 sevelamer hydrochloride를 이용한 치료에 의해 안정화 되었다. 결론적으로 본 증례의 경우 개에서 나타나는 원발성 부갑상선기능저하증의 임상증상과 특징적인 실험실 검사 결과 그리고, 치료 반응에 대한 국내 첫 증례보고이다.

• 한국임상수의학회지
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• 제24권1호
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• pp.68-72
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• 2007

An 8-year-old, male Shih-tzu dog with clinical signs of hemorrhage from penile orifice and pain on lifting hindlimb was brought to the Veterinary Medicine Teaching Hospital, Chungnam National University. The patient was shown polyuria/polydipsia (PU/PD), more than 10 times per day, and gasterointestinal signs such as intermittent vomiting and melena. On laboratory examination, BUN, creatinine and amylase level were all highly increased. Radiographic and ultrasonographic findings included that both kidneys were abnormal, and both prostates were hyperplastic bilaterally and cysts were presented in parenchyma. Additionally, hyperechoic pancreas and intact urinary bladder were observed from ultrasonographic examination. The dog was diagnosed as pancreatitis, acute renal failure and benign prostatic hyperplasia (BPH). After the appropriate treatment for pancreatitis and acute renal failure, He dog was treated with administration of azasteroid for BPH. On day 71 after azasteroid treatment, good response to the treatment was defined by ultrasonography and clinical signs cured completely.