• 제목/요약/키워드: Distribution Science Research

검색결과 9,196건 처리시간 0.054초

일부 치과 외래환자의 측두하악장애 실태와 음식섭취능력에 관한 연구 (A Study of Temporomandibular Disorders and Food Intake Ability among Dental Clinic Outpatients)

  • 한세영;유지수
    • 치위생과학회지
    • /
    • 제11권3호
    • /
    • pp.285-292
    • /
    • 2011
  • 본 연구는 치과의원에 내원한 일부 외래환자를 대상으로 측두하악장애 실태와 음식섭취능력을 파악하여 삶의 질을 향상하고자 대전광역시 소재 5개 치과의원에 내원한 외래환자 208명을 대상으로 2010년 1월부터 9월까지 구조화된 설문지를 이용하여 실시하였다. 측두하악장애의 주관적 증상, 악습관 및 이상기능, 음식섭취능력에 대해 조사 분석하여 다음과 같은 결과를 얻었다. 1. 조사대상자의 측두하악장애의 주관적 증상을 보면 악관절 동통 45.7%, 관절잡음 45.2%, 저작 시 동통 41.3%, 개구 시 동통 38.0%, 비저작시 동통 19.7%, 관절탈구 13.0% 순으로 나타났다. 2. 성별에 따른 측두하악장애의 주관적 증상을 보면 관절탈구별로는 남자군 18.0%, 여자군 8.3%로 관절탈구를 보였으며(p=0.038), 저작 시 동통별로는 남자군 49.0%, 여자군 34.3%로 저작 시 동통을 보였으며(p=0.031) 유의하게 높았다. 3. 성별에 따른 악습관 및 이상기능을 보면 이악물기별로는 남성군 35.0%, 여성군 22.2%로 이악물기를 보였으며(p=0.041), 이갈이별로는 남성군 21.0%, 여성군 9.3%로 이갈이를 보였으며(p=0.018) 유의하게 높았다. 4. 연령에 따른 측두하악장애의 주관적 증상을 보면 악관절 동통별로는 21-30세군에서 자주 27.8%, 가끔 25.0%로 52.8%가 악관절 동통을 보였으며(p=0.001) 유의하게 높았다. 5. 연령에 따른 악습관 및 이상기능을 보면 두통여부별로는 31세 이상군에서 48.3%가 두통을 보였으며(p=0.046) 유의하게 높았다. 6. 측두하악장애의 주관적 증상에 따른 음식섭취능력을 보면 관절잡음이 없는 군일수록(p=0.000), 저작시 동통이 없는 군에서(p=0.000), 악관절 동통이 없는 군 일수록(p=0.000) 유의하게 높았다. 7. 악습관 및 이상기능에 따른 음식섭취능력을 보면 이악물기가 없는 군에서(p=0.000), 이갈이가 없는 군에서(p=0.000), 두통이 없는 군에서(p=0.000) 유의하게 높았다. 8. 조사대상자의 측두하악장애에 따른 치료방법을 보면 휴식 30.8%, 물리치료 24.0%, 약물치료 16.4% 순으로 나타났다. 저작 시 동통별로는 저작 시 동통에서 36.0%로 약물치료가, 악관절 동통별로는 악관절 동통에서 자주 52.4%, 가끔 40.5%로 약물치료와 물리치료가 유의하게 높았다(p=0.000). 이상의 연구결과를 종합하여 볼 때 측두하악장애의 복합요인에 대한 관리 조사가 병행되어 치료 및 예방 등에 대한 프로그램의 구축과 음식섭취능력을 높여 삶의 질이 향상되어지도록 신체적, 사회적, 문화적, 심리적인 측면을 고려함과 동시에 개인차가 심하기 때문에 다각적인 후속 연구가 계속 되어져야 할 것으로 사료된다.

다시기 Landsat TM 영상과 기계학습을 이용한 토지피복변화에 따른 산림탄소저장량 변화 분석 (Change Analysis of Aboveground Forest Carbon Stocks According to the Land Cover Change Using Multi-Temporal Landsat TM Images and Machine Learning Algorithms)

  • 이정희;임정호;김경민;허준
    • 한국지리정보학회지
    • /
    • 제18권4호
    • /
    • pp.81-99
    • /
    • 2015
  • 가속되는 지구온난화로 인해 한반도 주변의 탄소순환에 대한 명확한 이해의 필요성이 제기되고 있다. 산림은 이산화탄소의 주요 흡수원으로 지상 탄소량의 대부분을 저장하고 있어 이에 대한 추정이 필요하다. 우리나라에서는 국가산림자원조사의 표본점에서 측정되는 헥타르당 임목축적량을 활용하여 산림 탄소저장량을 추정한다. 하지만 탄소저장량은 요약된 수치 형태로 발표하고 있어 탄소저장량의 공간적 분포를 파악하는 것이 어렵다. 본 연구에서는 토지피복변화가 빠르고 국가산림자원조사 표본점 배치가 부족한 도시지역을 대상으로 UNFCCC의 Approach 3와 Tier 3를 충족하는 격자 기반 산림탄소저장량을 추정하였다. 토지피복변화 및 산림탄소저장량은 1991, 1992, 2010, 2011년에 취득된 Landsat 5 TM 영상과 고해상도 항공사진, 제 3차 및 제 5, 6차 국가산림자원조사 자료를 이용하여 추정하였다. 토지피복변화는 기계학습을 이용하여 변화된 토지피복과 변화되지 않은 토지피복 항목을 한 번에 분류하여 추정하였으며, 산림탄소저장량은 반사도, 밴드비율, 식생지수, 지형변수를 입력변수로 하여 기계학습을 통해 추정하였다. 연구 결과, 산림이 그대로 산림으로 유지되는 지역의 경우 33.23tonC/ha의 흡수를 하였으며 비산림이 산림으로 변한 지역의 경우 이보다 큰 36.83tonC/ha의 흡수가 진행된 것으로 추정되었다. 산림이 비산림으로 바뀐 경우에는 -7.35tonC/ha로, 배출이 일어난 것으로 추정되었다. 본 연구를 통하여 토지피복변화에 따른 산림탄소저장량 변화를 정량적으로 이해할 수 있었으며, 향후 효율적인 산림관리에 기여할 수 있을 것으로 판단된다.

혈청단백질분획(血淸蛋白質分劃)에 대한 연구(硏究) (I, II) (Studies on Bovine Serum Protein Fractions (I, II))

  • 임봉호
    • 대한수의학회지
    • /
    • 제5권1호
    • /
    • pp.1-16
    • /
    • 1965
  • I. A Comparison of Sodium Sulfate Precipitation and Zone(Paper, Agar) Electrophoresis; Many kinds of techniques have been used for fractionating serum proteins. In the present study, using bovine serum, the fractions obtained with sodium sulfate were compared with those determined by zone electrophoresis. 1. Fibrinogen was precipitated with 4 to 10 percent of sodium sulfate. 2. ${\gamma}$-globulin required 10 to 16 percent of the salt for precipitation. 3. ${\beta}$-globulin began to precipitate at 12 percent sodium sulfate, and completed precipitation at approximately 26 percent in paper electrophoresis, while at 22 percent in agar electrophoresis. 4. ${\alpha}$-globulin completed precipitation at 13 to 28 percent sodium sulfate in paper electrophoresis and at 22 percent in agar electrophoresis. 5. Albumin began to precipitate at 14 percent of the salt, and was free from the mixture of globulins approximately at 28 percent in paper electrophoresis, while at 22 percent in agar electrophoresis. The results of comparing fractions by the two methods were as follows: 1. Euglobulin (15%) was equal to the sum of the most ${\gamma}$-globulin and a small quantity of the ${\alpha}$-, and ${\beta}$-globulins. 2. Pseudoglobulin I (15-17.5%) corresponded to the most ${\alpha}$-, ${\beta}$-globulins and a small quantity of albumin. 3. Pseudoglobulin II(18-22%) was a mixture of the ${\alpha}$-, ${\beta}$-globulins and albumin fraction. 4. Albumin (above 22%) contained the most albumin fraction separated by zone electrophoresis and a small quantity of the ${\alpha}$-, and ${\beta}$-globulins. As mentioned above the fractions obtained with sodium sulfate were a mixture of the various proportion of the fractions determined by zone electrophoresis. The solubility of serum fractions to sodium sulfate coincided with the mobility of those by zone electrophoresis. (By percent of sodium sulfate we mean gram of sodium sulfate contained in $100m{\ell}$ of solution). II. Immunological Studies on Serum Protein Fractions with Sodium Sulfate; In the previous report the fractions of bovine serum protein with sodium sulfate compared with those obtained by zone electrophoresis, and the findings were that the former contained various proportion components of the latter. In this study the author studied whether or not the fractions with sodium sulfate are simple component antigenically by immunoelectrophoresis and micro double diffusion test (Immuno-precipitation), using rabbit antiserum to bovine serum. In immunoelectrophoresis, normal bovine serum developed with rabbit antibovine serum showed about ten distinct precipitin arcs. The distribution of these arcs was as follows: 1 albumin, 2 ${\alpha}_1$-, 3 ${\alpha}_2$-, 2 ${\beta}_1$-, ${\beta}_2$-, and 1 ${\gamma}$-globulin (Fig. 7, 9). In micro double diffusion test, five to six precipitation bands could be seen between antigens and antibody, the order of the precipitation bands location is albumin, ${\alpha}$-, ${\beta}$-, and ${\gamma}$-globulin from the side of antiserum well (Fig.19). Frequently the ${\alpha}$-, and ${\beta}$-precipitation bands were separated into two or three precipitation bands, which indicated that these globuline are not a pure component antigenically as shown in immuno-electrophoresis. In both Immunological methods, the two ${\alpha}$-, ${\beta}$-precipitin arcs and bands appeared clear and strong, indicating that the two globulins reacted as strong antigens. The precipitate reaction of ${\gamma}$-globulin was shown at 12 to 16 percent sodium sulfate; ${\beta}$-globulin at 12 to 20 percent; ${\alpha}$-globulin at 12 to 22 percent (immuno-electrophoresis), at 12 to 26 percent (Diffusion); and albumin at above 22 percent. Antigenically euglobulin contained ${\gamma}$-, ${\beta}$-, and ${\alpha}$-globulins, Pseudoglobulin I and Pseudoglobulin II were composed of ${\alpha}$-, and ${\beta}$-globulins, and albumin was a mixture of ${\alpha}$-globulin and albumin determined by zone electrophoresis. The results indicated that the fractions of serum protein obtained by either method were constituents of various proteins antigenically except ${\gamma}$-globulin and albumin by Zone electrophoresis.

  • PDF

Relationship between Brand Personality and the Personality of Consumers, and its Application to Corporate Branding Strategy

  • Kim, Young-Ei;Lee, Jung-Wan;Lee, Yong-Ki
    • 마케팅과학연구
    • /
    • 제18권3호
    • /
    • pp.27-57
    • /
    • 2008
  • Many consumers enjoy the challenge of purchasing a brand that matches well with their own values and personalities (for example, Ko et al., 2008; Ko et al., 2006). Therefore, the personalities of consumers can impact on the final selection of a brand and its brand personality in two ways: first, the consumers may incline to purchase a brand or a product that reflects their own personalities; second, consumers tend to choose a company that has similar brand personalities to those brands that are being promoted. Therefore, the objectives of this study are following: 1. Is there any empirical relationship between a consumer's personality and the personality of a brand that he or she chooses? 2. Can a corporate brand be differentiated by the brand personality? In short, consumers are more likely to hold favorable attitudes towards those brands that match their own personality and will most probably purchase those brands matching well with their personality. For example, Matzler et al. (2006) found that extraversion and openness were positively related to hedonic product value; and that the personality traits directly (openness) and indirectly (extraversion, via hedonic value) influenced brand effects, which in turn droved attitudinal and purchase loyalty. Based on the above discussion, the following hypotheses are proposed: Hypothesis 1: the personality of a consumer is related to the brand personality of a product/corporate that he/she purchases. Kuksov (2007) and Wernerfelt (1990) argued that brands as a symbolic language allowed consumers to communicate their types to each other and postulated that consumers had a certain value of communicating their types to each other. Therefore, how brand meanings are established, and how a firm communicate with consumers about the meanings of the brand are interesting topics for research (for example, Escalas and Bettman, 2005; McCracken, 1989; Moon, 2007). Hence, the following hypothesis is proposed: Hypothesis 2: A corporate brand identity is differentiated by the brand personality. And there are significant differences among companies. A questionnaire was developed for collecting empirical measures of the Big-Five personality traits and brand personality variables. A survey was conducted to the online access panel members through the Internet during December 2007 in Korea. In total, 500 respondents completed the questionnaire, and considered as useable. Personality constructs were measured using the Five-factor Inventory (NEO-FFI) scale and a total of 30 items were actually utilized. Brand personality was measured using the five-dimension scale developed by Aaker (1997). A total of 17 items were actually utilized. The seven-point Likert-type scale was the format of responses, for example, from 1 indicating strongly disagreed to 7 for strongly agreed. The Analysis of Moment Structures (AMOS) was used for an empirical testing of the model, and the Maximum Likelihood Estimation (MLE) was applied to estimate numerical values for the components in the model. To diagnose the presence of distribution problems in the data and to gauge their effects on the parameter estimates, bootstapping method was used. The results of the hypothesis-1 test empirically show that there exit certain causality relationship between a consumer's personality and the brand personality of the consumer's choice. Thus, the consumer's personality has an impact on consumer's final selection of a brand that has a brand personality matches well with their own personalities. In other words, the consumers are inclined to purchase a brand that reflects their own personalities and tend to choose a company that has similar brand personalities to those of the brand being promoted. The results of this study further suggest that certain dimensions of the brand personality cause consumers to have preference to certain (corporate) brands. For example, the conscientiousness, neuroticism, and extraversion of the consumer personality have positively related to a selection of "ruggedness" characteristics of the brand personality. Consumers who possess that personality dimension seek for matching with certain brand personality dimensions. Results of the hypothesis-2 test show that the average "ruggedness" attributes of the brand personality differ significantly among Korean automobile manufacturers. However, the result of ANOVA also indicates that there are no significant differences in the mean values among manufacturers for the "sophistication," "excitement," "competence" and "sincerity" attributes of the corporate brand personality. The tight link between what a firm is and its corporate brand means that there is far less room for marketing communications than there is with products and brands. Consequently, successful corporate brand strategies must position the organization within the boundaries of what is acceptable, while at the same time differentiating the organization from its competitors.

  • PDF

한국산(韓國產) 산림조류(山林鳥類)의 서식생태(棲息生態) - 지리산지역(智異山地域)을 중심(中心)으로 - (Ecology of the Forest Birds in Mt. Chiri, Korea)

  • 최재식;김재생
    • 한국산림과학회지
    • /
    • 제80권2호
    • /
    • pp.162-176
    • /
    • 1991
  • 산림조류(山林鳥類)의 유치증식(誘致增殖)에 기여(寄與)할 목적(目的)으로 1986년(年) 11월(月)부터 1989년(年) 12월(月)까지 지리산(智異山)에 표고별(標高別)로 인공(人工)새집을 가설(架設)하여 이를 이용(利用)하는 조류상(鳥類相)과 번식생태(繁殖生態)를 조사(調査)하였던 바 그 결과(結果)는 다음과 같다. 1. 지리산(智異山)에서 관찰(觀察)된 조류(鳥類)는 총(總) 59종(種) 2,403개체(個體)로서 특(特)히 표고(標高) 1,400m 지역(地域)에서 희귀조류(稀貴鳥類)인 바위종다리 13개체(個體)와 천연기념물(天然紀念物)인 황조롱이, 솔부엉이, 올빼미 등(等)이 관찰(觀察)되었다. 2. 표고별(標高別) 조류(鳥類)의 서식구조(棲息構造)는 되새의 우점도(優占度)(41.33%)가 가장 높았으며 종다양도(種多樣度)는 표고(標高)가 증가(增加)함에 따라 낮아지는 경향(傾向)이었고 유사도지수(類似度指數)는 표고(標高)가 높은 지역간(地域間)에 유사성(類似性)이 있었다. 3. 주요수렵조류(主要狩獵鳥類)인 꿩과 멧비둘기가 표고(標高) 900m지역(地域)에까지 나타나서 특(特)히 수직적(垂直的) 서식한계(棲息限界)가 높았다. 4. 인공(人工)새집을 이용(利用)하는 조류(鳥類)는 소형조류(小型鳥類)인 박새, 진박새, 쇠박새, 곤줄박이, 동고비 등(等)으로서 특(特)히 산림(山林)이 울창한 지역(地域)보다 물과 먹이가 풍부(豐富)한 임연(林緣)이나 등산로변(登山路邊) 등(等)에 가설(架設)한 인공(人工) 새집을 많이 이용(利用)(92.5%)하였다. 5. 표고별(標高別) 이용율(利用率)은 500m지역(地域)은 86%, 900m지역(地域)은 96%, 1,400m지역(地域)은 98%, 1,700m지역(地域)은 90%였다. 6. 표고별(標高別) 번식률(繁殖率)은 6%~46%로서 지역간(地域間)의 차이(差異)가 많았으며 가장 많이 번식(繁殖)한 조류(鳥類)는 곤줄박이였는데 이의 산란기간(產卵期間)은 표고(標高) 500m지역(地域)에서는 4월(月) 15일(日)부터 5월(月) 22일(日)(n=22)까지였고 표고(標高) 1,700m지역(地域)에서는 13일(日)이 늦은 4월(月) 28일(日)부터 5월(月) 27일(日)(n=13)까지였다. 7. 4개지역(個地域)의 인공(人工)새집에서 번식(繁殖)한 곤줄박이와 동고비 등(等) 5종(種)의 유조(幼鳥)의 식이물(食餌物)은 거미류(類)(8.7%)를 제외(除外)한 참나무재주나방과 명나방 등(等)의 해충류(害蟲類)(91.3%)였다.

  • PDF

도라지 재배환경 및 토양 형태학적 특성 (Survey on Cultural Environment and Soil Morphological Characteristics of Platycodon grangiflorus)

  • 이영한;박상렬;류재산;임선택;고병구;윤한대
    • 한국토양비료학회지
    • /
    • 제32권3호
    • /
    • pp.215-222
    • /
    • 1999
  • 토양 이화학적 성질에 따른 도라지 재배적지를 경남 진주 6, 김해 7, 고성 3, 함안 6, 거창 4개소 강원도 홍천 6개소 등 32개소를 대상으로 분석한 결과는 다음과 같다. 기온은 발병율과 $Y=3.07X^2-87.16X+649.26(R^2=0.947^{**})$, 수량과 $Y=-478.68X^2+13403X-90836(R^2=0.763^*)$의 유의성 있는 상관이 있었다. 재배년수는 진주 8.0년으로 다년생이었고 홍천 1.30ha로 가장 넓었으며 김해가 0.08ha로 좁았다. 평균 퇴비시용량은 홍천이 $108Mg\;ha^{-1}$로 과다시용하는 경향이었고 김해지역이 $4.96Mg\;ha^{-1}$로 적게 시용하였다. 경사는 고성이 35.0%로 급경지였고 거창은 28%로 구릉지이며 진주, 김해, 홍천은 경사가 11.7 11.0, 7.5%로 기복지를 나타냈다. 배수상태는 거창, 김해, 진주, 고성지역이 양호한 반면 홍천, 함안은 불량한 편이었고 농가재배지의 포장방향은 거창, 진주, 고성이 동남향이었으며 김해, 함안, 홍천지역은 북서방향이었다. 재배년수가 긴 진주지역이 근경 4.20cm, 주당 근중 57g으로 수량이 $36.17Mg\;ha^{-1}$로 높게 나타났다. 발병율은 함안, 홍천지역이 각각 56.8, 52.5%로 높게 나타났고 고성 진주지역이 30.0. 32.2%로 낮게 나타났다. 발병율은 배수등급과 Y=19.1X-5.26($R^2=0.592{***}$)지형과는 Y=9.68X+10.77($R^2=0.205^{**}$)의 고도의 유의성 있는 정의상관을 나타냈고, 수량은 배수등급과 Y=-10X+42($R^2=0.348^{**}$), 지형과는 Y=-5.34X+34.5 ($R^2=0.134^*$)의 부의상관을 나타냈다.

  • PDF

플라스틱칩 결체(結締) 톱밥보드의 기계적(機械的) 및 물리적(物理的) 성질(性質)에 관(關)한 연구(硏究) (A Study on the Mechanical and Physical Properties of Sawdustboard combined with Plastic Chip)

  • 이필우;서진석
    • Journal of the Korean Wood Science and Technology
    • /
    • 제15권3호
    • /
    • pp.44-55
    • /
    • 1987
  • In order to study the effect of sawdustboard combined with plastic chips, 0.5mm($T_1$), 1mm($T_2$), 1.4mm($T_3$) thick nylon fiber. polypropylene rope fiber(RP), and 0.23mm thick moth-proof polypropylene net fiber(NP) were cut into 0.5, 1, 2cm long plastic chips. Thereafter, sawdustboard combined with plastic chips prepared as the above and plastic non-combined sawdustboard(control) were manufactured into 3 types of one-, two-, and three layer with 5 or 10% combination level. By the discussions and results at this study, the significant conclusions of mechanical and physical properties were summarized as follows: 1. The MORs were shown in the order of 3 layer> 2 layer> 1 layer among plastic non-combined boards, and $T_3$ < $T_2$ < $T_1$ < RP (NP(5%) < NP(l0%) among plastic combined boards. In 2cm long plastic chip in 1 layer board, the highest strength through all the composition was recognized. 1 layer board showing the lower strength with 0.5cm plastic chip rendered to the bending strength improvement by 2 or 3 layer board composition. On the other hand, 2 or 3 layer combined with 1, 2cm long polypropylene net fiber chips incurred MOR's conspicuous decrease requiring optimum plastic chip combined level and consideration to combined type. 2. MOE in plastic non-combined 3 layer board exhibited sandwich construction effect by higher resin content application to surface layer in the order of 3layer>1layer>2layer with the highest stiffness of the board combined with polypropylene chip, while nylon chip-combined board had little difference from plastic non-combined board. In relevant to length and layer effect, 3 layer board combined with the 0.5cm long polypropylene net fiber chip in 5% and 10% combined level presented 34-43% and 44-76% stiffness increase against plastic non-combined board(control), respectively. Moreover, in 1 layer board, 30% stiffness increase with 10% against 5% combined level in the 1 and 2cm long polypropylene net fiber chip was obtained. 3. Stress at proportional limit(Spl) showing the fiber relationship (r: 0.81-0.97) between MOR presented in the order of 1 layer<2 layer<3 layer in plastic non-combined board. Correspondingly, combined effect by layer and plastic chip length was similar to MOR's. 4. Differently from previous properties(MOR, MOE, Spl). work to maximum load(Wml) of 2 layer board approached to that of 3 layer board. Conforming the above phenomenon. 2 layer combined with 0.5cm long polypropylene net fiber chip kept the greater work than 1 layer. The polypropylene combined board superior to nylon -and plastic non - combined board seemed to have greater anti - failing capacity. 5. Internal bond strength(IB), in contrast to MOR's tendency. showed in the order of T1

  • PDF

Imaging Neuroreceptors in the Living Human Brain

  • Wagner Jr Henry N.;Dannals Robert F.;Frost J. James;Wong Dean F.;Ravert Hayden T.;Wilson Alan A.;Links Jonathan M.;Burns H. Donald;Kuhar Michael J.;Snyder Solomon H.
    • 대한핵의학회지
    • /
    • 제18권2호
    • /
    • pp.17-23
    • /
    • 1984
  • For nearly a century it has been known that chemical activity accompanies mental activity, but only recently has it been possible to begin to examine its exact nature. Positron-emitting radioactive tracers have made it possible to study the chemistry of the human mind in health and disease, using chiefly cyclotron-produced radionuclides, carbon-11, fluorine-18 and oxygen-15. It is now well established that measurable increases in regional cerebral blood flow, glucose and oxygen metabolism accompany the mental functions of perception, cognition, emotion and motion. On May 25, 1983 the first imaging of a neuroreceptor in the human brain was accomplished with carbon-11 methyl spiperone, a ligand that binds preferentially to dopamine-2 receptors, 80% of which are located in the caudate nucleus and putamen. Quantitative imaging of serotonin-2, opiate, benzodiazapine and muscarinic cholinergic receptors has subsequently been accomplished. In studies of normal men and women, it has been found that dopamine and serotonin receptor activity decreases dramatically with age, such a decrease being more pronounced in men than in women and greater in the case of dopamine receptors than serotonin-2 receptors. Preliminary studies in patients with neuropsychiatric disorders suggests that dopamine-2 receptor activity is diminished in the caudate nucleus of patients with Huntington's disease. Positron tomography permits quantitative assay of picomolar quantities of neuro-receptors within the living human brain. Studies of patients with Parkinson's disease, Alzheimer's disease, depression, anxiety, schizophrenia, acute and chronic pain states and drug addiction are now in progress. The growth of any scientific field is based on a paradigm or set of ideas that the community of scientists accepts. The unifying principle of nuclear medicine is the tracer principle applied to the study of human disease. Nineteen hundred and sixty-three was a landmark year in which technetium-99m and the Anger camera combined to move the field from its latent stage into a second stage characterized by exponential growth within the framework of the paradigm. The third stage, characterized by gradually declining growth, began in 1973. Faced with competing advances, such as computed tomography and ultrasonography, proponents and participants in the field of nuclear medicine began to search for greener pastures or to pursue narrow sub-specialties. Research became characterized by refinements of existing techniques. In 1983 nuclear medicine experienced what could be a profound change. A new paradigm was born when it was demonstrated that, despite their extremely low chemical concentrations, in the picomolar range, it was possible to image and quantify the distribution of receptors in the human body. Thus, nuclear medicine was able to move beyond physiology into biochemistry and pharmacology. Fundamental to the science of pharmacology is the concept that many drugs and endogenous substances, such as neurotransmitters, react with specific macromolecules that mediate their pharmacologic actions. Such receptors are usually identified in the study of excised tissues, cells or cell membranes, or in autoradiographic studies in animals. The first imaging and quantification of a neuroreceptor in a living human being was performed on May 25, 1983 and reported in the September 23, 1983 issue of SCIENCE. The study involved the development and use of carbon-11 N-methyl spiperone (NMSP), a drug with a high affinity for dopamine receptors. Since then, studies of dopamine and serotonin receptors have been carried out in over 100 normal persons or patients with various neuropsychiatric disorders. Exactly one year later, the first imaging of opitate receptors in a living human being was performed [1].

  • PDF

강원도 고랭지의 석비레 성토지 토양 특성 (Soil Characteristics of the Saprolite Piled Upland Fields at Highland in Gangwon Province)

  • 박철수;정영상;주진호;양재의
    • 한국토양비료학회지
    • /
    • 제37권2호
    • /
    • pp.66-73
    • /
    • 2004
  • 강원도 고랭지 원예작물 재배지 일대에 성행하고 있는 화강암류의 풍화모재(석비레) 성토 밭토양은 일종의 인위토(Anthrosols)를 이루고 있고. 이들은 환경훼손과 토사 및 양분유출의 문제점을 안고 있다. 이들의 이화학을 조사한 결과, 고랭지 석비 성토 밭토양의 자갈함량은 평창지역이 평균 16.7%, 홍천지역이 25.3%로 조사되었다. 평창지역 석비레 성토지의 토양 경도는 0-10 cm 깊이에서 0.04-7.48 MPa이었고, 11-40 cm 깊이에서 0,10-8.89 MPa로 표토와 심토 모두 변이가 매우 심하게 나타났으며, 용적밀도는 0-10 cm 깊이에서 평균 $1.15g\;cm^{-3}$이었으며, 11-40 cm 깊이에서 $1.32g\;cm^{-3}$이었다. 그리고 양이온교환용량과 유기물 함량은 각각 $7.1cmol_c\;kg^{-1}$$12.4g\;kg^{-1}$으로 낮았고, 유효인산의 함량은 $526mg\;kg^{-1}$으로 다소 높게 나타났다. 홍천지역 석비레 성토지의 양이온치환용량은 $7.0cmol_c\;kg^{-1}$으로 낮았고, 유기물함량과 유효인산은 각각 $462mg\;kg^{-1}$$27.4g\;kg^{-1}$으로 적정 수준이었다. 강원도 고랭지의 석비례 성토지의 이화학성을 전국 밭토양의 평균치와 비교한 결과, 유기물, 교환성양이온과 점토의 함량이 낮은 것으로 나타났고, 교환성양이온은 차이가 없었으며, 유효인산의 함량이 높은 것으로 나타났다. 화강암 풍화모재 성토지는 양이온교환용량이 낮은 입자로 이루어져 있고, 점토의 함량이 낮아서 응집력과 양분을 보유할 수 있는 능력이 대단히 취약하기 때문에 토사와 양분유실을 일으키므로 토양관리와 수질에 대한 관리가 시급한 문제로 대두되고 있다. 모재성토지에 대한 화학적 물리적 평가가 정밀하게 이루어져서 모재 성토에 대한 대안을 마련하고, 토양의 유실과 양분의 손실을 저감시킬 수 있는 방법의 개발이 빠른 시일 내에 적용되어야 모재를 성토하여 영농활동을 하는 고랭지 밭에서 환경친화형 지속농업이 실현될 수 있을 것으로 판단된다.

우리나라 표층토(表層土)의 인산흡수력(燐酸吸收力)에 관(關)한 연구(硏究) (Studies on the Absorption Capacity of Phosphorus of Korean Top-soils)

  • 박천서;한기학;임수길;이재현
    • 한국토양비료학회지
    • /
    • 제2권1호
    • /
    • pp.1-13
    • /
    • 1969
  • 토양조사(土壤調査)에서 채취(採取)된 층위별시료중(層位別試料中) 표층(表層) 30cm 내외(內外)까지의 표층토양시료(表層土壤試料) 129점(點)에 대(對)한 인산흡수계수(燐酸吸收係數)를 조사(調査)하고 토양(土壤)(Association)별(別)로 그 범위별(範圍別) 분포(分布)와 인산흡수계수(燐酸吸收係數)를 지배(支配)하는 수종이화학적성질(數種理化學的性質)에 대(對)하여 검토고찰(檢討考察)한 결과(結果)는 대략(大略) 다음과 같다. 1. 대체(大體)로 기경지(旣耕地)에 속(屬)하는 토양(土壤)(Association)의 표층토(表層土)는 미경지(未耕地)보다 인산흡수계수(燐酸吸收係數)가 낮다. 2. 양(陽)이온치환용량(置換容量)이 큰 토양(土壤)일수록 인산흡수계수(燐酸吸收係數)가 크다. 3. 각토양(各士壤)(Association)별(別) 인산흡수계수(燐酸吸收係數)를 지배(支配)하는 주요(主要) 인자(因子)는 다음과 같다. 가) 점토함유량(粘土含有量)이 주(主)로 인산흡수계수(燐酸吸收係數)를 지배(支配)하는 토양(土壤); (1) 하해혼성충적과부식질회색토(河海混成沖積寡腐植質灰色土) 및 충적토, (2) 곡간충적토 및 산록추적토(山麓推積土), (3) 중성내지석회암저구릉(中性乃至石灰岩低丘陵) 및 산록적갈색토(山麓赤褐色土). 나) 유기물함량(有機物含量)이 주(主)로 인산흡수계수(燐酸吸收係數)를 지배(支配)하는 토양(土壤); (1) 하성충적과부식질회색토(河成沖積寡腐植質灰色土) 및 충적토(沖積土). 다) 양(陽)이온치환용량(置換容量)과 점토함량(粘土含量)이 인산흡수계수(燐酸吸收係數)를 지배(支配)하는 토양(土壤); (1) 산성암산악암쇄토(酸性岩山岳岩碎土) 라) 양(陽)이온치환용량(置換容量)과 유기물함량(有機物含量)이 인산흡수계수(燐酸吸收係數)를 지배(支配)하는 토양(土壤); (1) 중성내지염기성암산악암쇄토(中性乃至鹽基性岩山岳岩碎土). 마) 유기물(有機物) 및 점토함량(粘土含量)이 주(主)로 인산흡수계수(燐酸吸收係數)를 지배(支配)하는 토양(土壤); (1) 산성암저구릉(酸性岩低丘陵) 및 산록적황색토(山麓赤黃色土). 4. 인산흡수계수측정(燐酸吸收係數測定)에 있어서 $2.5%(NH_4)_2HPO_4$를 사용(使用)한것(y)과 $P{\cdot}700ppm$$NaH_2PO_4$를 사용(使用)한것(x)간(間)에는 $y=2.716x+37(r=0.96^{**})$의 직선회귀관계(直線回歸關係)와 고도(高度)의 유의(有意)한 정상관(正相關)이 있었다.

  • PDF