• Genomics & Informatics
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• v.6 no.4
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• pp.231-234
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• 2008

Precise and reliable identification of CNV is still important to fully understand the effect of CNV on genetic diversity and background of complex diseases. SNP marker has been used frequently to detect CNVs, but the analysis of SNP chip data for identifying CNV has not been well established. We compared various normalization methods for CNV analysis and suggest optimal normalization procedure for reliable CNV call. Four normal Koreans and NA10851 HapMap male samples were genotyped using Affymetrix Genome-Wide Human SNP array 5.0. We evaluated the effect of median and quantile normalization to find the optimal normalization for CNV detection based on SNP array data. We also explored the effect of Robust Multichip Average (RMA) background correction for each normalization process. In total, the following 4 combinations of normalization were tried: 1) Median normalization without RMA background correction, 2) Quantile normalization without RMA background correction, 3) Median normalization with RMA background correction, and 4) Quantile normalization with RMA background correction. CNV was called using SW-ARRAY algorithm. We applied 4 different combinations of normalization and compared the effect using intensity ratio profile, box plot, and MA plot. When we applied median and quantile normalizations without RMA background correction, both methods showed similar normalization effect and the final CNV calls were also similar in terms of number and size. In both median and quantile normalizations, RMA backgroundcorrection resulted in widening the range of intensity ratio distribution, which may suggest that RMA background correction may help to detect more CNVs compared to no correction.

• Journal of the Korean Geotechnical Society
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• v.15 no.4
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• pp.261-277
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• 1999

The horizontal and vertical earth pressures in backfill space which is narrowly excavated like ditch are affected by the share of ditch backfill space and the wall friction between excavated surface and backfill soil. In this paper, for the excavated surface the Handy's equation of a symmetric vertical case and the Kellogg's equation of a symmetric sloped one are modified to show the minor principal stress arch for the unsymmetrical excavated backfill space. Compared with the soil test box result, a similarity in magnitude and distribution of backfill earth pressure shows that the earth pressure has been observed. The backfill earth pressure in unsymmetrically sloped space has been shown twice as much as the one in vertically excavated space and also remarkable decline of arching for the former case. It is verified that the earth pressure equation should account the shape and size of backfill space to calculate the earth pressure for similar structure to the one handled in this study.

• Journal of the Korean Geotechnical Society
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• v.15 no.4
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• pp.235-246
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• 1999

Some of the underground structures such as subway tunnels are constructed by open cut method, in which the ground is excavated, a structure installed, and after that the excavated space is backfilled. In this case, because of their narrow and constrained boundary conditions, the earth pressure induced by self-weight of the backfilled soil acting on the underground structures is different from that of the classical theory. The vertical and horizontal earth pressures acting on upper slab and side wall of the underground structures constructed by open cut method are affected by the backfill geometry. The laboratory model tests were performed in the conditions of a variety of the shapes of backfill geometry and wall friction. And their results were compared with those from theories. As a result, it was observed that the distribution of the earth pressure acting on the underground structure is affected by the shapes of backfill geometry, the width of backfill, the angle of excavation and the wall friction.

• Journal of Aerospace System Engineering
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• v.13 no.6
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• pp.52-59
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• 2019

The rotor blade is a key component that generates the lift, thrust, and control forces required for helicopter flight by the torque transmitted through the hub and the blade pitch angle control, and should be designed to factor vibration characteristics so that there is no risk of resonance with structural safety. In this study, the structural design of the main rotor blade for MPUH(Multi-Purpose Unmanned Helicopter) was conducted and the sectional stiffness measurement of the fabricated blade was performed. The evaluation of the vibration characteristics of the main rotor system was then conducted factoring the measured stiffness distribution. The interior of the rotor blade comprised of the skin, spar, and torsion box, and carbon and glass fiber composites were applied. The Ksec2D program was applied to predict the stiffness of blade, and the results were compared to the measured data. CAMRADII, a comprehensive rotorcraft analysis program, was applied to investigate the natural frequency trends and resonance risks due to the rotor rotation.

• Proceedings of the KIEE Conference
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• 2004.11c
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• pp.532-534
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• 2004

The advancement of electronics and telecommunication technologies has forced the risk management system for underground metallic structures to evolve into the remote monitoring and control system. Especially, facilities such as gas pipelines, oil pipelines and water distribution lines might make hazardous effect on human safety without continuous monitoring and control. As a result, pipeline engineers have applied cathodic protection system to prevent the degradation of their facilities by corrosion and carried out a periodic monitoring of the pipe-to-soil (P/S) potentials at numberous test boxes along their pipelines. The latter action on a road in downtowns, however, is so much dangerous that the inspectors should be ready to suffer the threatening of their lives and maintenance. In order to minimize these social costs and hazards, a stand-alone type corrosion monitoring equipment which can be installed in test box, store the P/S data for given Belied and send the data by wired/wireless telecommunications is under development. In order to obtain the exact P/S data, however, a reference electrode should be located as close to the pipeline as possible. Actually, the measured potential by a conventional portable reference electrode contain inevitably an IR drop portion caused by the current flow from the cathodic protection rectifier or the subway railroad. To minimize this error, it is recommended that the reference electrode should be buried within 10 cm from the pipeline. In this paper, we describe the design parameters for fabricating the permanent type reference electrode and the characteristics of the developed reference electrode.

• Journal of the Korean Data and Information Science Society
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• v.28 no.5
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• pp.959-970
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• 2017

In this study, we propose bivariate skewness and kurtosis statistics and suggest a surface plot that can visually implement bivariate data containing the correlation coefficient. The skewness statistic is expressed in the form of a paired real values because this represents the skewed directions and degrees of the bivariate random sample. The kurtosis has a positive value which can determine how thick the tail part of the data is compared to the bivariate normal distribution. Moreover, the surface plot implements bivariate data based on the quantile vectors. Skewness and kurtosis are obtained and surface plots are explored for various types of bivariate data. With these results, it has been found that the values of the skewness and kurtosis reflect the characteristics of the bivariate data implemented by the surface plots. Therefore, the skewness, kurtosis and surface plot proposed in this paper could be used as one of valuable descriptive statistical methods for analyzing bivariate distributions.

• Journal of KIISE
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• v.44 no.1
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• pp.71-77
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• 2017

There has been a recent spate in the usage of mobile device equipped GPS sensors, such as smart phones. This trend enables the posting of geo-tagged messages (i.e., multimedia messages with GPS locations) on social media such as Twitter and Facebook, and the volume of such spatial data is rapidly growing. However, the relationships between the location and content of messages are not always explicitly shown in such geo-tagged messages. Thus, the need arises to reorganize search results to find the relationship between keywords and the spatial distribution of messages. We find the smallest minimum bounding rectangle (MBR) that embedding k or more points in order to find the most dense rectangle of data, and it can be usefully used in the location search system. In this paper, we suggest efficient algorithms to discover a group of 2-Dimensional spatial data with a close distance, such as MBR. The efficiency of our proposed algorithms with synthetic and real data sets is confirmed experimentally.

• The Journal of the Korea Contents Association
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• v.17 no.10
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• pp.567-575
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• 2017

In this study, when diagnosis pancreatic cancer by dual time point PET/CT, we propose SUVm 2.52 as the threshold value for performing the dual time point PET/CT exam. The hypothesis of normal distribution was adopted through data conversion of 60 pancreatic diseases. The proposed SUVm2.52 boundary value showed a significance level that could be applied to both 120 and 180 minutes of delay time scan for pancreatic cancer determination (p<0.05). C-value variation shows that delay time 2 hour test is more useful than delay time 3 hour test. When the SUVm 2.52 is set to the boundary value and the double-time point PET/CT exam is performed, the probability of distinguishing cancer from inflammation in the delayed image is 95%. When the delayed test is performed with the proposed boundary value SUVm 2.52, Compared with general PET / CT scans, it is thought that it may be helpful to distinguish pancreatic cancer.

• Journal of Advanced Navigation Technology
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• v.21 no.1
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• pp.107-112
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• 2017

In recent years, electric shock accidents due to electric leakage currents of household appliances such as computers, TVs, refrigerators, and LED lights are continuously occurring in homes and industrial buildings. And it is not easy to check the leakage current of each household appliances connected in parallel at the rear end of the module. In addition, the leakage current flowing through the path of the normal current other than the existing current leakage circuit breakers are installed in the distribution box, only the function to cut off the power when the leakage. Therefore, there are various disasters such as electric shock and fire caused by short circuit of household appliances, and the risk of such leakage current is seriously presented. In this paper, we propose a method to implement a leakage monitoring system that can be monitored at all times using Zigbee communication based on IEEE 80215.4, which has advantages in low power and low cost among short range wireless communication systems.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.4
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• pp.1900-1907
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• 2012

Since the subpanels of polygonal-section shell have the corners of an obtuse angle larger than 90 degree unlike general plate or box-section structures, this could have an influence on forming nodal lines against local plate buckling or stress distributions. However, there is not sufficient material in the relevant study results or design recommendations. The very feasible models of the initial imperfections were acquired through the literature studies and then the parametric studies were conducted along with the initial imperfection models by using the finite element method. The parameters like the size of residual stresses, the portion of compressive residual stresses, and steel grades were considered. From the parametric studies, it was found that the maximum residual stress is more influential factor than the distribution pattern of residual stresses. In addition, The design strength equations for the simply supported plates can be applicable to the determination of the local buckling strength of the polygonal cross-section shell structures.