To validate the comparision of proximal and distal large intestinal motility, the amplitude and frequency of spontaneous motility, the effect of acetylcholine, the effect of atropine on the response of acetylcholine, the effect of histamine and the effect of pyrilamine and cimetidine on the response of histamine were investigated in rabbit. The results were summarized as follows: 1. The amplitude of spontaneous motility was more powerful on the proximal large intestine than that of the distal large intestine, but the frequency of spontaneous motility was similar on the both proximal and distal large intestine in rabbit. 2. Acetylcholine caused the contraction of proximal and distal large intestine, and the contractile response were increased between the concentration of acetylcholne $10^{-9}$ and $5{\times}10^{-6}M$ and $10^{-7}$ and $10^{-4}M$ on the proximal and distal large intestine, respectively, with dose-dependent manner in rabbit. 3. The contractile response induced by acetylcholine was completely blocked by the post-treatment with cholinergic receptor blocker, atropine $10^{-6}M$. 4. Histamine caused the contraction of proximal and distal large intestine and the contractile response were increased between the concentration of histamine $10^{-9}$ and $5{\times}10^{-5}M$ and $10^{-5}$ and $10^{-3}M$ on the proximal and distal large intestine, respectively, with dose-depend ent manner in rabbit. 5. The contractile response induced by histamine was completely blocked by the pretreatment with $H_1$-receptor blocker, pyrilamine $10^{-6}M$, but not blocked by the pretreatment with $H_2$-receptor blocker, cimetidine $10^{-6}M$.
The effect of splinting on aqbutment tooth distal movement was performed in vitro study. An acrylic resin mandibular model with missing 2nd premolars, molars and a removable partial denture framework were constructed. The roots of the canines, 1st premolars and edentulous ridges were coated with silicone rubber. A modified Ney Surveyor was used for vertical load appkication, and abutment tooth distal movement were measured with a dial gauge with four conditions of splinting methods were tested by applying unilateral vertical loadings. The results are follows; 1. The magnitude of abutment tooth distal movement on the non-load side was less 40$\sim$69% than that occurred on the load side. 2. On the load side, reducing effect of splinting on abutment tooth movement in the condition of load side double abutment(30%), non-load side double abutment(10%), double abutments of both sides(40%) was compared with single abutments of both sides. 3. On the non-load side, reducing effect of splinting on abutment tooth movement in the condition of load side double abutment(5%), non-load side double abutment(22%), double abutments of both sides(59%) was compared with single abutments of both sides. 4. The magnitude of abutment tooth distal movement in the condition of double abutments of both sides was less 40$\sim$59% than that in the condition of single abutments of both sides.
Purpose: To evaluate the effect on clinical course of heterotopic ossification of distal tibiofibular syndesmosis after ankle fractures. Materials and Methods: From June 2001 to May 2004, we found nine cases of heterotopic ossification of distal tibiofibular syndesmosis after ankle fractures. There were 8 male patients and 1 female patient; their mean age was 42 years old. There were 6 Weber type B and 2 Weber type C fractures, and there is 1 case with posterior malleolus fracture only. Among them, 8 ankle fractures were operated. Follow up period was averaged for 14 months. We were able to review radiographs at initial injury and to review clinical menifestation and radiographs at last follow up. We used an ankle-hindfoot scoring system of AOFAS which combined symptom, function and alignment with maximum score of 100 point. Results: In all cases ankle dorsiflexion and plantarflexion were not significantly different from that of the contralateral side. The patients who had developed heterotopic ossification in distal tibiofibular syndesmosis had a similar functional score. The mean ankle-hind foot score was 94 points. Conclusion: We concluded that the heterotopic ossification of distal tibiafibular syndesmosis after ankle fractures had little effect on clinical course and range of motion of ankle joint.
Objective : The purpose of this study is to compare the Effect of Acupuncture on Local Acupoints and Distal Acupoints for Patients with Whiplash Injury. Method : From January 1st 2009 to September 31th 2009, 10 patient were divided into 2 groups. One group was taken Local Acupoints, and the other group was taken Distal Acupoints. To check pain and treatment satisfaction, visual analog scale(VAS) and five-point likert scale were used before and after treatment. Result : Both acupuncture theraphy showed improvement in VAS and five-point likert scale. And Local Acupoints group showed more effective than Distal Acupoints group on five-point likert scale. Conclusion : This Study suggests that Acupuncture on Local Acupoints and Distal Acupoints can be applicable to improve symptom in Patients with Whiplash Injury.
Journal of Physiology & Pathology in Korean Medicine
/
v.22
no.6
/
pp.1518-1524
/
2008
Ponciri Fructus (PF), the immature fruit of Poncirus trifoliata, has been used for treatment of constipation in Korean traditional medicine. It has been reported that PF has a prokinetic effect on gastrointestinal tract, but little is known about the effect on colonic contraction. The aim of this study was to investigate the effect of PF on spontaneous contractions of proximal and distal colon in rats. The aqueous extract of PF was centrifuged and filtered and its supernatant was used for in vitro motility study. The removed colon from rats was divided into proximal and distal segments. Each segment was mounted in a 10 ml organ bath and measured the change of the spontaneous contraction with increasing dose (1, 5, 10, 50, 100, 500, $1000{\mu}g/ml$) of PF extract administration. Also the effect of PF on the spontaneous contraction was measured under treatment of atropine, acetylcholine (Ach), and tetrodotoxin (TTX). PF increased the spontaneous phasic contraction of distal colon dose dependently, but there was no change in proximal colon. The contractile response induced by PF in distal colon was lower than that of Ach and was partially blocked by atropine ($10^{-6}M$). TTX increased the spontaneous contraction and it was reinforced with Ach addition. But the extract of PF had no or little contractile effect of TTX in colon. PF increased spontaneous contractions selectively in distal colon. The prokinetic effect of PF may be due to enhancement of cholinergic related excitatory neural system.
Background: Significant discrepancy exists between anatomical plate designs and the anatomy of the native distal radius, which may be attributable to considerable morphometric variations in the volar aspect of the distal radius. We aimed to evaluate the degree of variability in the morphometry of the distal radius and identify factors associated with this variability. Methods: We measured the volar surface angle (VSA) of the intermediate and lateral columns and the volar surface width (VSW) in the distal radius from three-dimensional computed tomography scans acquired from 81 cadaveric forearms. These morphometric parameters were compared between the lateral and intermediate columns, between males and females, and between Koreans and Caucasians. Caucasian morphometric data were obtained and pooled from the previous studies. The coefficient of variation was used to assess the variability of the parameters and Cohen's d to estimate the effect size of the difference between groups. Results: The average VSA of the lateral column was $22^{\circ}{\pm}6^{\circ}$, and that of the intermediate column was $29^{\circ}{\pm}8^{\circ}$ in Koreans (p < 0.001). The variability was high for both VSAs. The VSA of the intermediate column was significantly larger in males than in females (p < 0.001) and in Caucasians than in Koreans (p < 0.001). The average VSW of distal radius was $30{\pm}3mm$ at the watershed line, and it became narrower proximally. The VSW was significantly larger in males than in females (p < 0.001) and in Koreans than in Caucasians (p < 0.001). The effect sizes of the difference for the VSA and VSW between sexes, races and columns were medium to large. Conclusions: Considerable variability exists in the morphometry of the volar distal radius, with sex, race, and column as contributing factors. These results suggest that surgeons should carefully choose an anatomical volar locking plate with appropriate angulation characteristics for each patient to achieve patient-specific alignment of the distal radius.
Journal of the Korean Society of Physical Medicine
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v.10
no.1
/
pp.1-7
/
2015
PURPOSE: The aim of this study was to investigate the effects of distal movement on shoulder muscle activation during diagonal pattern of exercises. METHODS: Seventeen healthy male participants volunteered to participate. Five muscles of shoulder were investigated during standing performance of diagonal shoulder exercises with and without visual trace. Two patterns of the diagonal exercises were used as diagonal 1 flexion and extension (D1F-E), and diagonal 2 flexion and extension (D2F-E). Two way repeated measures analysis of variance was used, which the factor was the presence of distal movement and exercise variations. RESULTS: The average muscle activity values of the lower trapezius and anterior deltoid are higher with the D2F-E, compared to the D1F-E (p<.05). The distal movement effect was observed within included all muscles except the lower trapezius, which the values are significantly greater in exercise with distal movement (P<.05). All significant increase of the muscles during the exercise with distal movement condition showed over 0.9 for the observed power in present study. CONCLUSION: Present result suggested that the diagonal pattern of exercise with distal movement has additional advantages of activating the scapulothoracic muscle as well as glenohumeral muscles. In addition, the D2F-E exercise pattern is effective for activating lower trapezius and anterior deltoid muscles.
Park, Jun-Soo;Lee, Sung-Bok;Kwon, Kung-Rock;Woo, Yi-Hyung
The Journal of Korean Academy of Prosthodontics
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v.45
no.4
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pp.444-456
/
2007
Statement of problem: Implant inclination and cantilever loading increse loads distributed to implants, potentially causing biomechanical complications. Controversy exists regarding the effect of the intentionally distal-inclined implant for the reduction of the cantilever length. Purpose: This study investigated the stress distribution at the bone/implant interface and prostheses with 3D finite element stress analysis by using four different cantilever lengths and implant inclinations in a mandibular implant-supported bar overdenture. Material and methods: Four 3-D finite element models were created in which 4 implants were placed in the interforaminal area and had four different cantilver lengths(10, 6.9, 4 and 1.5mm) and distal implant inclinations$(0^{\circ},\;15^{\circ},\;30^{\circ}\;and\;45^{\circ})$ respectively. Vortical forces of 120N and oblique forces of 45N were applied to the molar area. Stress distribution in the bone around the implant was analysed under different distal implant inclinations. Results: Analysis of the von Mises stresses for the bone/implant interfaces and prostheses revealed that the maximum stresses occurred at the most distal bone/implant interface and the joint of bar and abutment, located on the loaded side and significantly incresed with the implant inclinations, especially over $45^{\circ}$. Conclusion: Within the limitations of this study, it was suggested that too much distal inclination over 45 degrees can put the implant at risk of overload and within the dimension of the constant sum of a anterior-posterior spread and cantilever length, a distal implant inclination compared to cantilever length had the much larger effect on the stress distribution at the bone/implant interface.
According to previous studies, the effect of intrinsic motivation related variables such as cognitive absorption (CA) on the use of information technology(IT) should be mediated by the conscious intention. However, CA, which is a thought of previous emotional experience, a deep involvement with a software, may be one of environmental cues stimulating the use of IT independently of conscious intention. The objective of this study is to show the direct effect of CA on the automatic use of IT. For this purpose, as well as the relation between CA and use, two relations, CA-intention and intention-use, were also suggested as hypotheses, which will show that conscious intention would not fully mediate the relation between CA and automatic use. Moreover, for seeing the effects of CA as time passes, the proximal effect, which is short term and transitory effect, and the distal effect, which is long term and lingering, were simultaneously included in hyptheses. Finally, the effect of past use was also suggested as a hypothesis which aimed to show that automatic use would be controlled mostly by habit rather than not only intention but also CA. For the empirical validation of the hypotheses, 174 users of 'Cyworld', one of most influential social network services, were longitudinally surveyed, which showed that the hypotheses were accepted.
The purpose of this study was to analyze the magnitude and distribution of stress using a photoelastic model from the mandibular distal extension removable partial dentures with the mesial or distal placement of the occlusal rest and the mesial or distal connection in the back-action clasp with the five various designs of the back-action clasp, that is, the mesial connection and the distal rest, the distal connection and mesial rest, the mesial connection and mesial rest, the distal connection and the mesial and distal rest, and the mesial connection, and the mesial and distal rest. A photoelastic model was made of the epoxy resin(PC-1) and the hardner(PLH-1) with the acrylic resin teeth used and was coated with the plastic cement-1 at the lingual surface of the model and then five kinds of the removable partial dentures on the photoelastic model were set. A unilateral vertical load of 12.5 kg was applied on the central fossa of the first molar with the use of specially designed loading device and the pattern and distribution of the stress of the photoelastic model under each condition was analyzed by the reflective circular polariscope. The following results were obtained. 1. In the back-action clasp with the mesial connection and mesial rest of the case 3, the effect of the stress distribution was the most favorable. 2. In the back-action clasp with the mesial and distal rest, of the case 4 and 5, the stress distribution was more greatly showed in the terminal abutment. 3. Generally, the stress distribution was more favarable in the mesial connection than in the distal connection. 4. In the back-action clasp with the mesial connection of the case 1, 3 and 5, the stress distribution was the most favorable in the mesial rest.
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