• Korean Journal of Acupuncture
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• 제28권4호
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• pp.125-135
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• 2011

Objectives : This study is aimed to evaluate the diagnostic value of Ryodoraku for traditional Korean medicine practice reported in the Korean literature. Methods : A search of seven Korean databases was performed up to May 2011 using the search term 'Ryodoraku(in Korean)'. All clinical studies on diagnostic Ryodoraku characteristics were included. Results : The search yielded 59 studies, of which 5 were considered suitable for this analysis. Four were observational studies. Only one was a controlled trial. Average Ryodoraku score(RS), mean values for each measure point, physiologic limit, number of Pyesaek and Gyeokcha, and pattern classification were used as references for the analysis. Correlations were observed between average RS and idiopathic Parkinson's disease, some sub-groups of respiratory disease, chronic low back pain, and menopause. Some mean values for measure points showed particularly high or low tendencies in patients with idiopathic Parkinson's disease, chronic low back pain, and menopause. Positive correlations were observed between the number of Pyesaek and H-Y stage in idiopathic Parkinson's disease and F2(肝) and the modified Kupperman's index with menopausal women. The four classes, organized based on Ryodoraku pattern, showed differences in various characteristics. Conclusions : Since only five studies met the experimental conditions, this evaluation of the diagnostic value of Ryodoraku in various situations is limited. Future studies should be conducted using various physiologic and pathologic situations.

• 대한한방내과학회지
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• 제41권6호
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• pp.1141-1161
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• 2020

Objectives: Parkinson's disease (PD) is a neurodegenerative disease of the elderly characterized by impaired behavior from lack of dopamine secretion. However, no accurate quantitative diagnosis method has been established. The purpose of this study was to analyze the patent trends (PTs) of health examination and daily monitoring/healthcare technology for PD. Methods: For analyzing PTs, a search summary for classifying each analysis target technology was set, and a final search formula was constructed by collecting keywords. After constructing a database of related patents through the final search formula, noise was removed to extract valid patents. PTs by major countries were analyzed using the valid patents, and PTs and growth stages were analyzed by the detailed technologies. Results: The survey analysis showed that, despite the existence of unpublished patents between 2018 and 2020, patent activity has increased rapidly in the recent period, and this increasing trend was led by the USA. This technology is considered to be in its early- or mid-stage growth period, which means that the marketability is high and the barriers are low. Korea's market share is only about 25%, but it has a larger number of applications than those of Europe and Japan. Integrated monitoring and diagnosis technologies for PD have a share of 34%. Conclusion: The advances in diagnosis and healthcare technology for PD means that traditional Korean medicine must continue to pay attention to related technologies and to review plans that are applicable to clinical practice.

• 한국의사학회지
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• 제33권2호
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• pp.89-104
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• 2020

The purpose of this research is to build a database structure that can be useful for evidence-based medical practices by constructing the knowledge related to oriental medicine in the classical literature knowledge in a form that can utilize new forms of information technology. As a method, "database" is used as a keyword to search published studies in the field of oriental medicine, research is conducted on classic literature knowledge, and studies describing the contents of the data structure are found and analyzed. In conclusion, the original text DB for the preservation of the original texts and the presentation of the supporting texts should include 'Contents Text', 'Tree Structure', 'Herbal Structure', 'Medicine Manufacture', and 'Disease Structure' tables. In order to search, calculate, and automatically extract expressions written in the original text of the old literature, the tool DB should include 'Unit List', 'Capacity Notation List', 'CUI', 'LUI', and 'SUI' tables. In addition, In order to manage integrated knowledge such as herbal, medicine, acupuncture, disease, and literature, and to implement a search function such as comparison of similarity of control composition, the knowledge DB must contain 'dose-controlled medicine name', 'dose-controlled medicine composition', 'relational knowledge', 'knowledge structure', and 'computational knowledge' tables.

• Child Health Nursing Research
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• 제14권1호
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• pp.53-60
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• 2008

Background: Atopic dermatitis starts as an early childhood type I hypersensitivity to environmental allergens and is often the first step in the atopic march to develop into asthma and allergic rhinitis. Despite progress that has been achieved in management, this health problem remains poorly controlled and cause great pain and suffering for many children and their parents To introduce nurses to recent progress in pathophysiology, management and preventive measure of atopic disease. Search method: Systemic search was done using the PubMed and CINAHL from 1980 to 2005. In addition, historical references were taken from standard medical textbook. Results: In total, 30 relevant publications were located including primary research and review articles that cover the pathophysiology, management, and preventive measure of atopy. The evidence emerging from literature indicate that non-medical approaches such as breastfeeding and probiotics would improve management outcomes. Conclusion: The review suggests that breastfeeding and probiotic approaches would be the most effective preventive measures for children with atopic diseases.

• 한국한의학연구원논문집
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• 제18권1호
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• pp.1-11
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• 2012

The objective of this article is to investigate from what kind of disease Queen Inhyun(仁顯王后) died through the clinical records written in Seungjeongwon Ilgi("承政院日記"). The method to do this study was to search the records of Seungjeongwon Ilgi("承政院日記") from Sukjong 26th year to 27th year on the website databased and serviced by National Institute of Korean History. The results was as follows. According to the website search, Queen Inhyun(仁顯王后) suffered from purulent coxarthritis for one and a half year. As time passed by, the lesion of disease spread to her abdomen and heart. Finally, she died of difficulty in breathing.

• 대한융합한의학회지
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• 제1권1호
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• pp.5-15
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• 2021

Objectives: To review the concept of Moebius syndrome. Methods: Literature search was done to study definition, epidemiology, pathophysiology, clinical feature, and treatment of Moebius syndrome. Pubmed, RISS, Google scholarship and uptodate scholastic were used in the research. Search words were 'Moebius syndrome', 'treatment of Moebius syndrome'. Only English and Korean studies were assessed. Results: Moebius syndrome is rare disease characterized by nonprogressive congenital uni- or bi-lateral facial (VII cranial nerve) and abducens (VI cranial nerve) palsy. This facial palsy is found across the world, and its incidence is approximately 1 per 250,000. Moebius is diagnosed by clinical features. Facial palsy, eye abduction problem, limb deformities, global cerebral nerve impairment can be shown. Rehabilitation, smile surgery, and acupuncture can be used to treat this. Conclusion: Moebius syndrome's epidemiology, pathogenesis, treatment is still not fully revealed. It is known to be a congenital disease which didn't have exact treatment except surgery. But, it needs further study about exact treatment, diagnosis, and pathogenesis.

• Genomics & Informatics
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• 제2권3호
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• pp.131-133
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• 2004

MediScore is an information retrieval system, which helps to search for the set of genes associated with a specific disease or the set of diseases associated with a specific gene. Despite recent improvement of natural language processing (NLP) and other text mining approaches to search for disease associated genes, many false positive results come out due to diversity of exceptional cases as well as ambiguities in gene names. In order to overcome the weak points of current text mining approaches, MediScore introduces statistical normalization based on binomial to normal distribution approximation which corrects inaccurate scores caused by common words not representing genes and interactive rescoring by the user to remove the false positive results. Interactive rescoring includes individual alias scoring for each gene to remove false gene synonyms, referring MEDLINE abstracts, and cross referencing between OMIM and other related information.

• 한국융합학회논문지
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• 제9권10호
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• pp.467-475
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• 2018

본 연구는 당뇨병성 신증 환자들의 자가 관리 연구에서 사용된 측정도구를 고찰함으로써 이후 자가 관리를 사정하기 위한 기초 자료로 이용하고자 시행되었다. 4개의 국외 데이터베이스 이용하였고, 검색용어로는 "Diabetes Mellitus", "Self-care", "Kidney Disease"가 사용되었다. 그 결과 8개의 연구가 선정되었고, 8개의 도구가 연구에서 사용되었다. 그러나 이 도구들은 전반적인 환자 또는 당뇨병 환자, 혈액투석 환자를 대상으로 개발되어, 실제 당뇨병성 신증 환자의 특이성을 지닌 도구는 확인되지 않았다. 따라서 앞으로 당뇨병에서 신장질환으로 이행될 때 변화되는 당뇨병성 신증의 특이성을 고려한 자가 관리를 확인하기 위한 측정도구 개발 연구가 이루어져야 할 것이다.

• 사상체질의학회지
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• 제26권3호
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• pp.251-261
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• 2014

Objectives This research was proposed to present Clinical Practice Guideline(CPG) for Soyangin Disease of Sasang Constitutional Medicine(SCM): Yin-Depletion (Mangeum) Symptomatology. The CPG was developed by the national-wide experts committee consisting of SCM professors. Methods The CPG was developed by the national-wide experts committee considering of the society of Sasang Constitutional Medicine. It was performed by search and collection of literature related SCM, opinion of SCM experts and journal search and it was followed by CPG's guideline. Results & Conclusions The CPG of Yin-Depletion (Mangeum) Symptomatology in Soyangin Disease include classification, definition and standard symptoms of each pattern. Yin-Depletion (Mangeum) Symptomatology is classified into severe and critical pattern by severity. The severe pattern of Yin-Depletion (Mangeum) Symptomatology is classified into the pattern of Heat-related diarrhea accompanied by headache (Sinyeol-dutong Mangeum) and the advanced pattern of Heat-related diarrhea accompanied by headache (Sinyeol-dutong Mangeum). The critical pattern of Yin-Depletion (Mangeum) Symptomatology is classified into the pattern of Cold-related diarrhea accompanied by the abdominal pain (Sinhan-bocktong Mangeum) and the advanced pattern of Cold-related diarrhea accompanied by abdominal pain (Sinhan-bocktong Mangeum).