• Journal of the Korean Society of Environmental Restoration Technology
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• v.18 no.2
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• pp.119-131
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• 2015

The purpose of this study was to compare the differences of the ecological attributes in the two types of urban park at Suwon and Goyang city. 'Directly linked park' is forests and rivers in the vicinity, it is capable of re-supply of the species and 'Isolated park' is forests and rivers apart, it is a difficult re-supply of the species. The result of assessment of the ecological attributes in the two types of urban park was analyzed as the percentage of 'Forest zone' was high, but the percentage of 'Area of permeable pavement' and 'Bush area' was low. 'The planting structure' was mostly 1-layer structure(47%) and 'Foreign tree species' is high by half the proportion. 'Age classes' were a 2-3age classes level, and 'Water body' could barely. Thus, ecological attributes degree was very low. In addition, results of investigation whether the difference of ecological attributes degree between the two types of urban park, also statistically analyzed that there is no difference. Therefore, when establishing the composition of the future plans of the city park, to take full account of the ecological situation in the surrounding parkland, and identify the ecological potential with the parkland. Next, it should be designed and planned of the park that fully utilizing the potential of this ecological attributes.

• Journal of the Korean Data and Information Science Society
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• v.25 no.6
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• pp.1531-1538
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• 2014

The causes of cancer are diverse, complex, and only partially understood. Many factors including health behaviors, socioeconomic environments and geographical locations can directly damage genes or combine with existing genetic faults within cells to cause cancerous mutations. Collecting the cancer data and reporting the statistics, therefore, are important to help identify health trends and establish normal health changes in geographical areas. In this article, we analyzed cancer data and demon-strated how spatial patterns of the age-standardized rate and health indicators can be examined visually and simultaneously using linked micromap plots. As a result of data analysis, the age-standardized rate has positive correlativity with thyroid and breast cancer, but the rate has negative correlativity with smoking and drinking. In addition, the regions with high age-standardized rate are located in southwest and the areas of high population density while the standardized mortality ratio is higher in southwest and northeast where there are lots of rural areas.

• Genomics & Informatics
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• v.3 no.4
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• pp.154-158
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• 2005

Germ-line mutations of the BRCA1 gene confer an increased risk for breast and ovarian cancers. BRCA1 in female cells is directly related with the maintenance of the inactive X chromosome (Xi). The effect by the loss of the BRCA1 function on the X chromosome gene expression remains unclear in cancer cells. We attempted to investigate the expression pattern of the X-linked genes by performing BRCA1 knockdown via RNA interference in the MCF7 breast cancer cell line. The transcriptional and translational levels of BRCA1 were decreased over 95% in the MCF7 cells after BRCA1 knockdown. The expression patterns of one hundred ninety X-linked genes were profiled by the X chromosome-specific cDNA arrays. A total of seven percent of the X-linked genes (14/190) were aberrantly expressed by over 2-fold in the MCF7-BRCA1 knockdown cells, which contained two up-regulated genes (2/190, 1 %) and 12 down-regulated genes (12/190, 6.3%). It is interesting that 72% of the aberrantly expressed X-linked genes were located on the Xq (10/14,) region. Our data suggests that BRCA1 may not be important to maintain X chromosome inactivation in cancer because the BRCA1 knockdown did increase the expression of the only one percent of X-linked genes in the human breast cancer cells.

• Proceedings of the KIEE Conference
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• 2006.10c
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• pp.336-338
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• 2006

Motorized retractors enhance the safety of passengers by removing the slack of webbing and by holding upright driving position. Reliability of a driving mechanism that includes one-way clutch between the driving motor and webbing is directly linked to the safety of passenger. In this research, conditions for locking one-way clutch and also conditions for sustaining locking are theoretically investigated. the operation of a motorized retractor under realistic conditions is simulated in order to validate the proposed retractor design.

• Journal of the Korean Home Economics Association
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• v.47 no.9
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• pp.71-82
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• 2009

The purpose of this study was to explore the effects of child gender and temperament, husbands’ support, and mothers’ psychological well-being on maternal parenting behaviors toward toddlers. Mothers of 214 toddlers responded to questionnaires on the following variables: child temperament, husbands’ support, psychological wellbeing and parenting behaviors. Hierarchical regression analysis revealed that: 1) Children being negative emotionality linked with mothers’ high controlling and rejective parenting behaviors and low responsive parenting behaviors directly and indirectly via mothers’ psychological well-being; 2) Husbands’ support was linked with mothers’ low controlling and rejective behaviors through mothers’ high psychological well-being; 3) Mothers’ low psychological well-being was linked to high mothers’ controlling and rejective parenting. The results of this study underscore mothers’ psychological well-being and husbands’ parenting support in predicting mothers’positive parenting.

• Journal of Society of Preventive Korean Medicine
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• v.11 no.1
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• pp.45-53
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• 2007

Homocysteine is a sulfur amino-acid produced during the metabolism of the essential amino acid methionine. Moderately increased plasma total homocysteine concentration have been implicated as a risk factor for occlusive vascular disease. Smoking is known to be one of the most significant factors leading to elevated plasma homocysteine concentration. However, the main component of a cigarette, nicotine has been not studied whether it is linked directly to the increase of homocysteine concentration in blood. The metabolism of homocysteine is closely linked to that of its cofactors, folate. Here, the effects of nicotine and folic acid on amount of plasma homocysteine were studied. The concentration of homocysteine was increased by about 70% in rat plasma after nicotine treatment for one month. This increased concentration of homocysteine was reduced by about 60% at 6 hours later after folate treatment. Thus, nicotine should be directly involved in increasing the concentration of plasma homocysteine. Also it is suggested that these results can be and applied and used for controlling withdrawal symptoms after stopping smoking as one of oriental medicine formulas.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.17 no.2
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• pp.125-136
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• 2014

Urban Green Area has ecologically deteriorated along with quantitative loss, being developed as a dot itself rather than connected to forests and green networks around the park. The present study aims to propose a connected plan on Urban Ecological Network establishment through 'assessment of the connectivity of the entire urban parks' in accordance with distance of forest and river and 'assessment of trends in connection fragmentation of urban parks' in accordance with the past change of forest and river. According to the result of this study, criteria based on previous research was "directly linked type is less than 300m, conceptually linked type is between 300m to 1km, the isolated type is greater than 1km". And the result of 'assessment of the connectivity of the entire urban parks' is analyzed as the rate of park and green network, 41.7% in Suwon, 80.0% in Seongnam, 88.9% in Namyangju on the basis of office and field investigation. Also, according to the result of 'assessment of trends in connection fragmentation of urban parks', consideration for connection to the original forest is insufficient.

• Journal of Contemporary Eastern Asia
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• v.14 no.1
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• pp.5-22
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• 2015

This study examines how different uses of social network sites (SNS) and mobile phones (MP) to communicate with friends and business associates are related to the acquisition of job-related information, job mobility, and entrepreneurial intentions, using social capital as its main theoretical lens. To this end, a nationally representative, random digit dialing (RDD) survey was conducted in Singapore. Path analyses show that SNS interactions with friends are positively related to both bonding and bridging social capital. The former is linked with greater job mobility, the latter with entrepreneurship, and both are associated with more job-related information. SNS interactions with business contacts are directly positively related to job-related information and entrepreneurship. For mobile phones, interactions with friends are positively related to social capital, job information and entrepreneurship. Professional networking is associated with more bridging social capital, job information and job mobility. Bonding capital is found to be linked with greater job mobility, while bridging capital has a positive relationship with both entrepreneurship and job mobility.

• International Journal of Precision Engineering and Manufacturing
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• v.3 no.3
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• pp.28-36
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• 2002

The continuously variable transmission (CVT) mechanism considered here is the output coupled type which combines the functions of a 2K-H I type differential gear unit and a V-belt type continuously variable unit (CVU). One shaft of the CVU is connected directly to the output shaft and another shaft of it is linked to the differential gear unit. It is shown that some fundamental relations (speed ratios, power flows and efficiencies) for twelve mechanisms previously described are valid by various experimental studies, six of them produce a power circulation and the others produce a power split. Parametric analysis is carried out in relation to the efficiency, speed ratio and power ratios in order to assist in the design of an optimum configuration. Some useful properties associated with power flow modes also are discussed in the output coupled type continuously variable transmission.

• Archives of Pharmacal Research
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• v.19 no.3
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• pp.235-239
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• 1996

Six, heretofore undescribed, $5^I-Methyl-5^I-(5-Substituted uracil-1-ylmethyl)-2^I-oxo-3^I-methylenetetrahydrofurans(F, Cl, Br, l, CH_3, H)(6a-f)$were synthesized and evaluated against three cell lines (FM-3A, P-388 and U-937). For the preparation of .alpha.-methylene-.gamma.-butyrolactone bearing 5-substituted uracils (6a-f), the effcient Reformatsky type reaction was employed which involves the treatment of ethyl .alpha.(bromomethyl) acrylate and zinc with the respective 5-substituted uracil-1-ylacetones (5a-f). The acetone derivatives (5a-f) were directly obtained by the respective alkylation reaction of 5-substituted uracils with chloroacetone in the presence of $K_{2}$$CO_{3}$(or NaH). These lactone compounds 6a-f exhibited moderate to significant activity in all of the three cell lines, and 6b, 6c and 6e showed significant antitumor activities (inhibitory concentrations ($IC_{50}$) ranged from 1.3-3.8 .mu.g/ml.