• Title/Summary/Keyword: Direct Aging

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Research Trends of Psychology Studies Published in 『Journal of the Korean Gerontological Society』 (『한국노년학(韓國老年學)』의 심리학 분야 연구동향)

  • Jung, Taeyun;Youn, Gahyun
    • 한국노년학
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    • v.38 no.3
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    • pp.767-782
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    • 2018
  • Academic research of the elderly psychology flourishes in an aging society. The basic concern of both psycho-gerontology dealing with psychological processes of aging and geronto-psychology dealing with psychology of the elderly is with the maintenance of high quality of life and well-being. Given this context, the present study examined research trends of 91 depression and suicide studies and 31 aging and successful aging studies, and compared the trends with those identified in studies published within the first 30 years. It was found that a majority of studies are concerned with the direct or mediating effects of depression on suicide and everyday life, risk factors influencing depression, perceptions of aging and factors influencing those perceptions, and successful aging and factors influencing successful aging. Further, the number of studies of these topics is greater than that of studies published within the first 30 years. The findings were discussed in the context of heightening the quality of life of the older adults.

An Evaluation of Moisture Sensitivity of Asphalt Concrete Pavement Due to Aging (노화에 따른 아스팔트 콘크리트 포장의 수분민감성 평가)

  • Kim, Kyungnam;Kim, Yooseok;Kim, Nakseok
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.39 no.4
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    • pp.523-530
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    • 2019
  • Pavement distress and traffic accidents are caused by pot-hole. In addition, direct and indirect damages of road users are increasing, such as loss of life due to personal injury and damage to vehicles. Generally, the asphalt concrete pavements are continuously aging from the production process to the terminal performance period. Aging causes stripping due to cracks and moisture penetration and weakening the pavement structure to induce pot-hole. In this study, adhesion performance and moisture sensitivity were evaluated according to aging degree in order to investigate the effect of aging on asphalt pavement. As a result of the study, the viscosity of the asphalt binder was increased with aging and the bond strength of the aged was increased 2~3 times than that of the unaged. The results of accelerated aging test showed an increases in indirect tensile strength and the increase in the TSR (Tensile Strength Ratio) by 4.2~8.9 %. As a result, it is noted that the anti-stripping and adhesion performances of the aged asphalt concrete are improved compared to the unaged one under the aging conditions of asphalt binder coated on aggregates.

Impact of mesenchymal stem cell senescence on inflammaging

  • Lee, Byung-Chul;Yu, Kyung-Rok
    • BMB Reports
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    • v.53 no.2
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    • pp.65-73
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    • 2020
  • Life expectancy has dramatically increased around the world over the last few decades, and staying healthier longer, without chronic disease, has become an important issue. Although understanding aging is a grand challenge, our understanding of the mechanisms underlying the degeneration of cell and tissue functions with age and its contribution to chronic disease has greatly advanced during the past decade. As our immune system alters with aging, abnormal activation of immune cells leads to imbalance of innate and adaptive immunity and develops a persistent and mild systemic inflammation, inflammaging. With their unique therapeutic properties, such as immunomodulation and tissue regeneration, mesenchymal stem cells (MSCs) have been considered to be a promising source for treating autoimmune disease or as anti-aging therapy. Although direct evidence of the role of MSCs in inflammaging has not been thoroughly studied, features reported in senescent MSCs or the aging process of MSCs are associated with inflammaging; MSC niche-driven skewing of hematopoiesis toward the myeloid lineage or oncogenesis, production of pro-inflammatory cytokines, and weakening their modulative property on macrophage polarization, which plays a central role on inflammaging development. This review explores the role of senescent MSCs as an important regulator for onset and progression of inflammaging and as an effective target for anti-aging strategies.

Telomerase reverse transcriptase in the regulation of gene expression

  • Zhou, Junzhi;Ding, Deqiang;Wang, Miao;Cong, Yu-Sheng
    • BMB Reports
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    • v.47 no.1
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    • pp.8-14
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    • 2014
  • Telomerase plays a pivotal role in the pathology of aging and cancer by maintaining genome integrity, controlling cell proliferation, and regulating tissue homeostasis. Telomerase is essentially composed of an RNA component, Telomerase RNA or TERC, which serves as a template for telomeric DNA synthesis, and a catalytic subunit, telomerase reverse transcriptase (TERT). The canonical function of TERT is the synthesis of telomeric DNA repeats, and the maintenance of telomere length. However, accumulating evidence indicates that TERT may also have some fundamental functions that are independent of its enzymatic activity. Among these telomere-independent activities of hTERT, the role of hTERT in gene transcription has been investigated in detail. Transcriptional regulation is a fundamental process in biological systems. Several studies have shown a direct involvement of hTERT in gene transcription. This mini-review will focus on the role of hTERT in gene transcription regulation, and discuss its possible mechanisms.

Two Factors Failure Model of Oil-Paper Insulation Aging under Electrical and Thermal Multistress

  • Li, Jian;Wang, Yan;Bao, Lianwei
    • Journal of Electrical Engineering and Technology
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    • v.9 no.3
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    • pp.957-963
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    • 2014
  • Converter transformers play important roles in high-voltage direct current transmission systems. This paper presents experimental and analysis results of the combined electrical and thermal aging of oil-impregnated paper at pulsating DC voltages. Breakdown voltages and time-to-breakdown of oil-paper specimens were measured by using short-time and constant-stress tests. The breakdown characteristics of combined electrical and thermal aging on insulation system were discussed. According to the relationship between failure time and aging temperature, the two-parameter Weibull model was improved. On the basis of the competing risk algorithm and the improved Weibull model, the two factors failure model was calculated. And the influence of temperature in the insulation system has been analyzed. This model performs better than the two-parameter Weibull model when both time and temperature are considered as variables in estimating the lifetime of oil-paper insulation.

A Structural Analysis of Successful Aging Factors for Korean Elderly (한국 노인의 성공적인 노화요인의 구조분석)

  • Kim, Kyoung-Ho;Kim, Ji-Hoon
    • 한국노년학
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    • v.29 no.1
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    • pp.71-87
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    • 2009
  • The purpose of this study were to identify factors of successful aging and to suggest a successful aging model of elderly using Rowe & Kahn's model of successful aging. The components of the factors consisted of healthful status, physical·cognitive functions, psychosocial characteristics and productive activities. Data were collected from 2,958 elderly who has spouse and aged 65 above in KOSA Panel. Data were analyzed by Amos program 7.0 version. The statistical techniques were used descriptive statistics χ2 and covariance structural analysis. Major findings of this study were as follows; Healthful status were positively related to increasing effort on physical·cognitive functions as well as psychosocial characteristics. Physical·cognitive functions were positively and directly related to psychosocial characteristics and productive activities. Psychosocial characteristics were positively and directly related to productive activities. Physical·cognitive functions and psychosocial characteristics were increased by receiving a direct and positive effort from healthful status. Productive activities were increased by receiving a direct and positive effort from physical·cognitive functions and psychosocial characteristics. Specific and realistic measures should be prepared for successful aging not only for present elderly but also for the future elderly people. Further research should be continued and encouraged to improve the implications for the successful aging especially in korea.

Relationship between Oxidation and Wear of Ultra-High Molecular Weight Polyethylene for Total Joint Arthroplasty

  • Lee, Kwon-Yong
    • KSTLE International Journal
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    • v.2 no.1
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    • pp.55-58
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    • 2001
  • The most widely-used orthopaedic grade polymer bearing liner material, ultrahigh molecular weight polyethylene (UHMWPE), for the total joint arthroplasty degrades after gamma-irradiation sterilization through the progressive oxidation in a shelf and in vivo. Oxidative degradation makes UHMWPE brittle and leads to decrease in mechanical properties. In this study the relationship between post-gamma-irradiation aging time and wear of UHMWPE was investigated. Six retrieved polyethylene hip liners implanted for 3-16 years and then stored in air for 1.5-6.5 years until tests were used. Two types of pin-on-disk wear testing were conducted by the uni-directional repeat pass rotating and by the linear reciprocating stainless steel disks against stationary polyethylene pins under 4Mpa at 1Hz with bovine serum lubrication in ambient environment. Wear of retrieved polyethylene hip liners does not have direct correlation with in vivo or total aging time. Linear reciprocal sliding motion generated more remarkable wear than uni-directional repeat pass sliding motion. It indicates that kinematic motion affects very crucially on the wear of aged UHMWPE having brittle white band region.

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The Effects of Emotional & Social Preparation for Aging on Successful Aging of the Elderly with Disability & Mediating Effects of Social Support (정서사회적 노후준비가 장애노인의 성공적 노화에 미치는 영향과 사회적 지지의 매개효과)

  • Song, Kee-Young
    • The Journal of the Korea Contents Association
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    • v.18 no.7
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    • pp.194-206
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    • 2018
  • The purpose of this research is to take a look at the factors that influence the successful aging of the elderly with disability as the aging population grows. For this purpose, psychological and social concepts were defined for successful aging of the elderly with disability. It was also verified that the effects of emotional & social preparation for aging on successful aging of the elderly with disability and mediating effects of social support. The subjects of this study are 506 elderly people with disability who are over the age of 50. They were originally extracted from the 4th main survey and 3rd, 4th additional survey of Korean Retirement and Income Study. For data analysis purposes, SPSS 23.0 and SPSS PROCESS macro v2.16 were used. The results of this study are as followed. Firstly, emotional & social preparation for aging turned out to have a significant direct influence on successful aging the elderly with disability. Secondly, emotional & social preparation for aging has a indirect effect on successful aging through social support. On the basis of the results, this study provided the social welfare policy and practical suggestions to enhance the preparation for aging and social support.

The Effects of Emotional & Social Preparation for Aging on Successful Aging & Mediating Effects of Social Support (정사사회적 노후준비가 성공적 노화에 미치는 영향과 사회적 지지의 매개효과)

  • SONG, Keeyoung
    • The Journal of the Convergence on Culture Technology
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    • v.4 no.4
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    • pp.47-56
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    • 2018
  • The purpose of this research is to take a look at the factors that influence the successful aging as the aging population grows. For this purpose, psychological and social concepts were defined for successful aging of the elderly with disability. It was also verified that the effects of emotional & social preparation for aging on successful aging and mediating effects of social support. The subjects of this study are 3,910 who are over the age of 65. They were originally extracted from the 4th main survey and 3rd, 4th additional survey of Korean Retirement and Income Study. For data analysis purposes, SPSS 25.0 and SPSS PROCESS macro v2.16 were used. The results of this study are as followed. Firstly, emotional & social preparation for aging turned out to have a significant direct influence on successful aging. Secondly, emotional & social preparation for aging has a indirect effect on successful aging through social support. On the basis of the results, this study provided the social welfare policy and practical suggestions to enhance the preparation for aging and social support.

Microstructural Feature and Aging Characteristics of Spray-Formed Cu-5Ni-10Sn Alloy (가스분무성형 Cu-5Ni-10Sn 합금의 미세조직 및 시효강화)

  • Roh, Dae-Gyun;Kang, Hee-Soo;Baik, Kyeong-Ho
    • Journal of Powder Materials
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    • v.19 no.4
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    • pp.317-321
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    • 2012
  • In this study, Cu-5Ni-10Sn(wt%) spinodal alloy was manufactured by gas atomization spray forming, and the microstructural features and mechanical properties of Cu-5Ni-10Sn alloy have been investigated during homogenization, cold working and age-hardening. The spray formed Cu-5Ni-10Sn alloy consisted of an equiaxed microstructure with a mixture of solid solution ${\alpha}$-(CuNiSn) grains and lamellar-structure grains. Homogenization at $800^{\circ}C$ and subsequent rapid quenching formed a uniform solid solution ${\alpha}$-(CuNiSn) phase. Direct aging at $350^{\circ}C$ from the homogenized Cu-5Ni-10Sn alloy promoted the precipitation of finely distributed ${\gamma}$' or ${\gamma}-(Cu,Ni)_3Sn$ phase throughout the matrix, resulting in a significant increase in microhardness and tensile strength. Cold working prior to aging was effective in strengthening Cu-5Ni-10Sn alloy, which gave rise to a maximum tensile strength of 1165 MPa. Subsequent aging treatment slightly reduced the tensile strength to 1000-1100 MPa due to annealing effects.