• 한국초전도ㆍ저온공학회논문지
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• 제24권2호
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• pp.1-6
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• 2022

This paper reviews the literature that has been published since 1980s related to cryogenic refrigeration systems for quantum computing. The reason why such a temperature level of 10-20 mK is necessary for quantum computing is that the superconducting qubit is sensitive to even very small thermal disturbances. The entanglement of the qubits may not be sustained due to thermal fluctuations and mechanical vibrations beyond their thresholds. This phenomenon is referred to as decoherence, and it causes an computation error in operation. For the stable operation of the quantum computer, a low-vibration cryogenic refrigeration system is imperative as an enabling technology. Conventional dilution refrigerators (DR), so called 'wet' DR, are precooled by liquid helium, but a more convenient and economical precooling method can be achieved by using a mechanical refrigerator instead of liquid cryogen. These 'dry' DRs typically equip pulse-tube refrigerators (PTR) for precooling the DRs around 4 K because of its particular advantage of low vibration characteristic. In this review paper, we have focused on the development status of 4 K PTRs and further potential development issues will be also discussed. A quiet 4 K refrigerator not only serves as an indispensable precooler of DR but also immediately enhances the characteristics of low noise amplifiers (LNA) or other cryo-electronics of various type quantum computers.

• 산업경영시스템학회지
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• 제39권3호
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• pp.1-9
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• 2016

NSS (Navigation satellite system) provides the information for determining the position, velocity and time of users in real time using satellite-networking, and is classified into GNSS (Global NSS) and RNSS (Regional NSS). Although GNSS services for global users, the exactitude of provided information is dissatisfied with the degree required in modern systems such as unmanned system, autonomous navigation system for aircraft, ship and others, air-traffic control system. Especially, due to concern about the monopoly status of the countries operating it, some other countries have already considered establishing RNSS. The RNSS services for users within a specific area, however, it not only gives more precise information than those from GNSS, but also can be operated independently from the NSS of other countries. Thus, for Korean RNSS, this paper suggests the methodology to design the satellite constellation considering the regional features of Korean Peninsula. It intends to determine the orbits and the arrangement of navigation satellites for minimizing PDOP (Position dilution of precision). PGA (Parallel Genetic Algorithm) geared to solve this nonlinear optimization problem is proposed and STK (System tool kit) software is used for simulating their space flight. The PGA is composed of several GAs and iterates the process that they search the solution for a problem during the pre-specified generations, and then mutually exchange the superior solutions investigated by each GA. Numerical experiments were performed with increasing from four to seven satellites for Korean RNSS. When the RNSS was established by seven satellites, the time ratio that PDOP was measured to less than 5 (i.e. better than 'Good' level on the meaning of the PDOP value) was found to 94.3% and PDOP was always kept at 10 or less (i.e. better than 'Moderate' level).

• 대한기계학회논문집B
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• 제35권5호
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• pp.525-531
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• 2011

디젤엔진에서 배기가스 재순환(EGR; Exhaust Gas Recirculation)은 선택적 환원 촉매나 $NO_x$ 흡장 촉 매에 비해 $NO_x$ 배출 저감을 위한 가장 효과적인 기술이다. 점점 더 강화되어 가는 $NO_x$ 배출 규제를 만족시키기 위해서는 많은 양의 EGR 가스 공급이 필요하다. 저압 EGR은 일정한 과급 압력에서 가변형상 터보차져의 제어와 거의 독립적이기 때문에 EGR 공급 측면에서 보면 저압 EGR이 기존의 고압 EGR에 비해서 더 많은 장점을 갖는다. 본 연구에서는 저압 EGR이 연소 특성에 미치는 영향을 고압 EGR을 적용했을 때와 비교하였다. 각 EGR 루프에 대해 혼합기의 희석 정도에 따른 영향을 분석하기 위해 독립변수로써 희석비를 사용하였다. 저압 EGR을 적용하였을 때, 고압 EGR을 적용했을 때와 동등한 $NO_x$ 배출량을 유지하면서 연료 소비율과 매연 배출은 고압 EGR의 경우보다 좀 더 낮은 결과를 보였다.

• Parasites, Hosts and Diseases
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• 제23권1호
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• pp.95-101
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• 1985

Fascioliasis in cattle is one of the most common and very serious trematode diseases in Korea. In the present study, the enzyme linked immunosorbent assay (ELISA) was applied in the diagnosis of fascioliasis using antigen of Fasciela hepatica, perokidase of conjugate anti-cattle Is G and orthophenylenediamine as a substrate by micro-method technique of Volley et at. (1976b) and MacLaren (1978) with a slight modification. Results obtained from the present study are as follows. 1. In assay for optimal dilution of stock antigen, the antigen (protein contents; 0. Bmgymz) was diluted from 1150 to 1/600 with carbonate buffer (pH 9.6), and then absorbance values were measured with 1/100 diluted sera. The regression equations between the OD values of ELISA and dilution of antigen were log Y: -0.181-0.00127X in infected sera, and log Y: -0.578-0. 000879X in normal sera. The significantly higher (p<0.05) OD value was observed in the former. 2. In assay for optimal dilution of sera, the sera were diluted from 1125 to 1/400 with in PBSJ Tween 20 (pH 7.4), and absorbance values were measured with 1/200 diluted antigen. The regression equation between the OD values of ELISA and dilution of sera were log Y: -0.1540-0.0007238X in infected sera and log Y: -0.4834-0.00116X in normal sera. The former was higher than the latter (p<0.05). 3. In the 27 cases of negative intradermal test, OD values of the ELISA are $0.447{\pm}0.144$, the 95% confidence interval (Mean+2 H SD) of the values was 0.735, and there was no case over the values. Therefore, the sensitivity of the antigen to diagnose fascioliasis was 100% in the negative case. The OD value 0.7 which is designed as a criterion (detection level of positive one) is useful for the performance of the ELISA in fascioliasis. 4. According to the OD value of criterion in the regression equations, the optimal dilutions of stock antigen and serum were 1/250 and 1/100, respectively. 5. In the 58 cases of fascioliasis from which the adult could be found in the bile ducts, the OD value was $0.846{\pm}0.224$. The 75% (44 cattle) among them had higher value with compared to the criterion, and the 60% (20 cattle) of the cases of proliferative cholangitis of 33 cattle which had been infected previousely with Fasciola sp. is higher than the criterion. 6. Prevalence of fascioliasis was 43.4% in the application of the ELISA to 272 cattle which were reared in Jeonbug district.

• 한국초지조사료학회지
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• 제25권1호
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• pp.1-6
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• 2005

With recent interest organic farming the use of legumes including vetch and clover to provide N to adjacent crops is increasing in Korea. In the present studies, we conducted a trial to investigate the effects of the application of N rate on nitrogen fixation and transfer from vetch to barley in mixed stands. The experiment was arranged in a randomized complete block design with three replications. Four different N rates(0, 75, 113 and 150/ha) was used and vetch+barley was broadcasted manually on 1.5 $\times$2 m plot in Oct. 2001. Half of urea and K$_{2}O, 200 Phosphate and 75 kg potash per ha were applied as basal dressing md half of N md 75 potash were used for topdressing to soil surface on MarctL 2002. The equivalent of 1kg ha$^{-1}$ at($^{15}$NH$_{4}$)$_{2}$SO$_{4}$ solution at 99.8 atom $\%$$^{15}$N excess was applied to the microplot in mid April. Forage was harvested from each plot at ground level and separated into barley and vetch. Total N content and It values of samples were determined using a continuous flow stable isotope ratio mass spectrometry(IsoPrime-EA. Micromass, UK.). The percentage of legume H fixed from atmospheric N2 were 95.0, 93.8, 94.4 and $84.8\%$ with increment of N levels. The percentage of N transfer from vetch to barley by N-difference method with increment of N fertilizer were from 58 to$49\%$ while 39 to $23\%$ in $^{15}$N-dilution method. The amount of transfer from vetch to barley were 87 to 68 kg/ ha with N level by N-difference moth여 and 58 to -56/ha with N application levels by $^{15}$N dilution method. The amount of nitrogen fixation per ha were from 150 kg / ha to 219 kg / ha by different method, but on the other side 49 to 105kg/ha by N$^{15}$-dilution.

• 한국방사선학회논문지
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• 제14권7호
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• pp.981-989
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• 2020

본 연구는 Pitch의 변화에 따른 CT 감약계수(CT Number)와 잡음(Noise)의 변화를 정량적으로 측정하고자 자체 제작한 맞춤형 팬텀(Customized Phantom)을 사용하였다. 팬텀을 이용한 영상의 획득을 위해 팬텀 내부는 멸균증류수로 가득 채웠다. 유리관 내부에는 생리식염수와 조영제의 비율을 각각 생리식염수 100%, 400:1, 200:1, 100:1, 50:1로 희석한 용액을 담은 후 영상화하였고, 이때 용액의 희석비율별로 pitch를 0, 0.35, 0.7, 1.05, 1.4의 단계로 나누어 각각 영상화하였다. 희석비율별로 모든 ROI에서 측정한 CT number와 noise 값의 평균이 pitch의 변화에 따라 유의한 차이를 보이는지 검증하고자 일원 배치 분산분석(One-way ANOVA Analysis)과 사후검정을 시행하였다. 실험 결과 각 희석비율별 pitch의 변화에 대한 CT number의 변화는 통계적으로 유의한 차이가 없었지만, noise 값은 pitch의 증가에 따라 증가하는 경향을 보였으며, 통계적으로도 유의한 차이를 보이는 것으로 나타났다. 나선형 영상획득 방식은 pitch에 따라 noise가 유의한 수준으로 달라질 수 있다. 따라서 나선형 영상획득 방식을 적용한 CT 영상의 화질평가 항목과 기준을 설정할 필요가 있을 것이다.

• 미생물과산업
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• 제16권3호
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• pp.2-5
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• 1990

IgA is the predominant immunoglobulin isotype in mucosal secretions(1). It has been reported that a population of Peyer's patch T cells can selectively induce IgM bearing B cells to switch to surface IgA bearing B cells(2,3). Further, IL-4, IL-5, and IL-6 alone and in combination, can significantly influence murine IgA B cell differentiation in vitro(4-7). However, it remains an open question which cytokines have a major role in class switching to the IgA isotype. Recently, it has been reported that transforming growth factor .betha.1(TGF .betha.1) alone, or in combination with IL-2 increases IgA secretion by LPS-activated surface IgA negative (sIgA$\^$-/) murine spleen B cells while concurrently downregulating IgM and IgG secretion by such cells(8-11). In the present study, limiting dilution analysis was used to demonstrate, at the clonal level, that TGF .betha.1 has siginificant activity as an IgA isotype switch factor.

• 한국초지조사료학회지
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• 제36권4호
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• pp.318-324
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• 2016

본 연구는 전남농업기술원 답리작 시험포장에서 2006년과 2007년 사이에 보리와 이탈리안 라이그래스와 각종 두과를 혼파비율을 달리한 처리하여 파종하였다. 주구는 보리 및 이탈리안 라이그래스와 자운영, 크림손클로버, 헤어리벳치, 사료용 완두였고 세구는 화본과와 두과를 각각 50:50, 60:40, 70:30 그리고 80:20이었다. 공중질소 고정량 및 이의 이동을 측정하기 위하여 질소동위원소($^{15}N(NH_4)_2SO_4$)를 2007년 4월 15일 처리 후 쿼드랏 안의 식물체를 6월 8일에 수확하여 화본과 및 두과로 분리한 후 안정성동위원소 질량분석기를 이용하여 분석하였다. 공중질소 고정률은 두과에서 화본과로, 질소이동은 차이법과 동위원소 희석법을 이용하여 구하였다. 본 실험결과의 주요내용은 동위원소 초과는 화본과에서는 차가 없었던 반면 보리와 두과와 혼파비율이 60:40인 처리에서 유의적인 차이가 있었다. 그 값은 보리와 혼파한 두과는 0에서 0.54 범위였다. 이탈리안 라이그래스와 두과 혼파에서는 초과 값이 더 높아 보리에서는 0.71에서 0.82, 두과는 0.37에서 1.01 사이였다. 공중 질소 이용비율은 보리와의 조합은 0%~49.5%, 이탈리안 라이그라스 조합은 0~60.5%의 범위로 다양한 결과를 나타내었다. 차이법에 의한 이동량 시험에서는 보리와의 조합에서 12.3~90.9 kg/ha, 이탈리안 라이그래스 조합에서는 보리보다 더 많아 31.7~107.8 kg 사이였다. 한편 동위원소 희석법에서는 보리와 두과 혼파조합은 0~36.1 kg/ha 그리고 이탈리안 라이그래스와 두과 혼파에서는 0~50.6 kg/ha로 이탈리안 라이그래스 조합이 더 많은 것으로 나타났다. 차이법에 의한 질소 이동량이 동위원소 희석법보다 더 많은 것으로 나타났다.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2001년도 추계학술발표대회
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• pp.99-102
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• 2001

본 연구에서는 히루딘을 생산할 수 있는 재조합 S. cerevisiae 에서 ‘히루딘 유전자의 copy number 와 히루딘 발현양과의 관계를 규명하였으며 , ${\delta}$ 서열을 이중으로 사용한 히루딘 발현벡터를 제조하여 히루딘 유전자의 효모염색체로의 도입효율을 증가시켰다. 숙주세포인 효모의 GALl 유전자를 파쇄하여 균체에 의한 갈락토스 소모를 방지하여 보다 경제적으로 히루딘을 생산할 수 있는 시스템을 개발하였으며, 재조합 H. polymorpha을 이용한 발효공정에서 히루딘 생산을 위한 최적의 메탄올 농도를 결정하였다.

• 한국수정란이식학회지
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• 제32권1호
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• pp.9-15
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• 2017

The present study was aimed to determine the effect of green tea extract (GTE) and beta-mercaptoethanol (${\beta}$-ME) supplementation in boar sperm freezing extender on sperm motility, viability and reactive oxygen species (ROS) level. Experimental groups were allocated into Lactose-egg yolk (LEY) without antioxidant (control), GTE (1,000 mg/L GTE in LEY) and ${\beta}$-ME ($50{\mu}M$ ${\beta}$-ME in LEY). Spermatozoa extended with LEY were cooled to $5^{\circ}C$ for 3 h and then kept at $5^{\circ}C$ for 30 min following dilution with LEY containing 9% glycerol and 1.5% Equex STM (final sperm concentration: $1{\times}10^8/mL$). Spermatozoa were loaded into straws and frozen in nitrogen vapor for 20 min. Following thawing at $37^{\circ}C$ for 25 sec, sperm viability and ROS level were measured using fluorescent double stain Fertility(R) and cytometry, respectively. Motility and viability of GTE supplemented-group were higher than those of control and ${\beta}$-ME without significance. ROS level in GTE group showed significantly lower than control (P < 0.05). In conclusion, GTE supplementation in boar sperm freezing extender can reduce ROS generation during freezing.