• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2022년도 춘계학술발표대회
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• pp.721-723
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• 2022

미디어에서 자극적으로 다루어지는 치매라는 질환을 한 가족의 이야기를 통해 긍정적인 시선으로 볼 수 있도록 스토리텔링 중심의 컴퓨터 2D 인디 게임을 디자인 및 개발한다.

• 디지털융복합연구
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• 제16권4호
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• pp.221-229
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• 2018

본 연구의 목적은 신체억제대를 적용한 치매노인 환자의 구체적인 특성과 부작용 발생 관련성을 파악하기 위함이었다. 2016년 5개 요양병원에서 치매노인에게 신체억제대를 적용한 간호사, 간호조무사, 요양보호사를 대상으로 구조화된 설문지를 이용하여 자료를 수집하였다. 190개의 자료를 SPSS 21.0의 신뢰도 분석, 기술통계, 카이제곱검정으로 분석하였다. 연구결과 '75- 84세' 연령의 환자가 58.3%, 1일 총 적용시간 중 '17-24시간'인 환자가 22.6%, 밤에 적용한 환자가 57.4%, 낙상과거력이 없는 환자가 54.2%를 차지하였다. 연령은 국소부종, 관절구축과 관련성이 있으며 특히 85세 이상의 환자에서 관절구축의 발생빈도가 25%로 나타났다(p<.05). 보행능력은 욕창과 관련이 있었으나 걸을 수 없는 환자보다 걸을 수 있는 환자의 욕창 발생빈도가 오히려 더 많았다. 총 적용시간은 피부발적, 국소부종, 관절구축의 3가지 부작용과 관련성이 있음을 알 수 있었다(p<.05). 본 연구를 기초로 신체억제대를 적용한 환자 돌봄 시 연령과 총 적용시간을 고려한 접근이 필요함을 제언하는 바이다.

• 디지털융복합연구
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• 제15권4호
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• pp.511-519
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• 2017

본 연구는 낮 병동 입원 치매 환자를 대상으로 작업치료 융복합활동프로그램을 실시하여, 치매환자의 손 기능, 인지기능, 수단적일상생활활동에 미치는 영향에 대해 알아보았다. 치매환자 34명을 대상으로 작업치료 융복합활동프로그램과 약물을 동시에 실시한 실험군 17명과 약물치료만 한 17명을 대조군으로 하여 24주간 주 8회 192회기로 실시하였다. 중재 전과 후의 손기능을 알아보기 위해 손의 장악력 검사를 실시하였고, 인지기능을 알아보기 위해 MMSE-K와 GDS를 실시하였다. 또한 수단적일상생활활동을 알아보기 위해 K-IADL를 이용하였다. 중재 결과 실험군에서는 손기능, 인지기능 및 수단적 일상생활활동이 유의하게 증진했지만, 약물치료만 한 대조군에서는 손기능, 인지기능, 수단적 일상생활활동의 증진이 보이지 않았다. 따라서 본 연구 결과 작업치료 융복합활동프로그램은 손기능, 인지기능, 수단적일상생활활동에 긍정적인 영향을 미친다는 것을 알 수 있다.

• 동의생리병리학회지
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• 제34권2호
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• pp.81-87
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• 2020

Cognitive impairment is symptoms of dementia, a degenerative brain disease that is drawing attention in a rapidly aging society. This study was conducted to investigate the improvement of cognitive function of Leonurus japonicus on scopolamine-induced memory impairment in mice and the effect and mechanism of memory recovery. In vivo studies were conducted on mice orally pretreated with L. japonicus in doses of 50, 100 and 200 mg/kg (p.o.) and scopolamine (1 mg/kg, i.p.) were injected 30 min before the behavioral task. Antioxidant activity was assessed by 2,2-diphenyl-1-picryl hydrazyl (DPPH) assay and 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay, and acetylcholinesterase (AChE) inhibition activity evaluated by Ellman's method. In behavior studies showed that L. japonicus has an improved the memory of scopolamine-treated mice in Y-maze, passive avoidance and Morris water maze test. In addition, L. japonicus was also exerted free radical scavenging activity and inhibited acetyl cholinesterase activity. These results suggest that L. japonicus improves short-term and long-term memory in scopolamine-induced memory decline model and prevents scopolamine-induced memory impairments through in reduced oxidative stress and acetyl cholinesterase inhibition effect. Thus, L. japonicus is related to functional medicinal materials for prevention and treatment of human dementia patients.

• International Journal of Contents
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• 제6권3호
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• pp.30-37
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• 2010

This paper aims to propose a cognitive evaluation model to be utilized in designing game devices and developing relevant software with the purpose of the prevention of dementia of the elderly among various types of serious games for the elderly intending to improve their physical, mental or social capability. Firstly, a serious game for the elderly has been developed based on the guidelines of the areas pertaining to existing hardware, software and contents. Secondly, a pre-experiment of the game targeting specialists has been conducted in order to re-establish a cognitive evaluation model for the developed result. Thirdly, the cognitive evaluation model for the serious game for the elderly that intends to improve their cognitive capacity has been materialized based on the experiment results. Given the fact that the scope of game contents, most of which used to be focused on teenagers, have been gradually expanding to cover wider range of social classes than ever before, it is expected that the results of this study could be utilized as a model that can verify the games and their contents with special purposes based on the cognitive evaluation of the users.

• 대한통합의학회지
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• 제8권4호
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• pp.49-58
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• 2020

Purpose : This study examined the effect of a home visit cognitive training program that uses a tablet-based digital recognition rehabilitation application, Brain Doctor, on local elderly people's cognitive function and depression. Methods : This study featured 20 elderly people living in Busan Metropolitan City, South Korea, who received a voucher for a home visit service to prevent dementia. The subjects were evenly divided into an intervention group provided with Brain Doctor and a control group provided with a conventional cognitive training program. Korean version of Mini Mental State Examination (MMSE-K) and Korean version of Montreal Cognitive Assessment (K-MoCA) were used to assess cognitive function in each group. Patient Health Questionnaire-9 (PHQ-9) was used to evaluate the depression levels. Results : The intervention group showed a significant change in cognitive function and depression after the intervention (p<.05). There was a statistically significant change in cognitive function and depression between the intervention and control groups (p<.05). Conclusion : This study confirmed that Brain Doctor had a positive effect on the cognitive function and depression of elderly people in the local community. It is expected to become a useful home visit program for dementia prevention in the future.

• 동의신경정신과학회지
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• 제34권3호
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• pp.141-150
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• 2023

Objectives: This study aimed to comprehend the characteristics of Korean medicine patterns in relation to varying degrees of cognitive impairment in an elderly population. Methods: The dataset included 127 elderly individuals with cognitive impairment obtained from three Korean medicine hospitals between 2018 and 2021. The participants were categorized into two groups based on Clinical Dementia Rating-Sum of Boxes (CDR-SB) scores: those with questionable impairment (QI) and those with very mild dementia (VMD). A diagnostic framework for Korean medicine patterns encompassing Qi deficiency, Yin deficiency, Phlegm dampness, and Heat-fire was employed. Liver blood markers, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), and the AST/ALT ratio, were also analyzed. Results: The scores of the cognitive assessment tools (MoCA-K, MMSE-DS, and K-IADL) of the QI group significantly differed from those of the VMD group. CDR-SB exhibited a positive correlation with the scores of each pattern of Qi deficiency, Yin deficiency, Phlegm dampness, and Heat-fire, whereas ALT and AST values displayed negative correlations. Binomial logistic analysis, controlling for potential confounders, such as age, education years, body mass index, the presence of chronic disease, and the presence of medication, verified that the VMD group showed higher pattern scores and lower ALT and AST values than the QI group. Conclusions: Increases in pattern scores along with decreased AST and ALT levels might be indicative of more severe cognitive impairment.

• 디지털산업정보학회논문지
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• 제6권3호
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• pp.1-8
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• 2010

Recently, the missing due to the heinous crimes occurred in succession has been the focus of attention, so measures for these are urgently needed. So, it is necessary that we need to check and take care the weak like children, women, the elderly with dementia and insane person to prevent these social problems. This study is location-based service that suggests the tracking system and way to guard a family and property from the various risk factors which are possible in our life. To acquire the location of the user who is in motion, a communications network technologies were integrated and the system will be able to be monitoring in real time through the website. So, it is convenient and safe because it is possible to use anywhere. Concretely, it was described around location-based service, GPS system, tracking system, process of the service solution and composition for the system. Also, the way to activate the system will be suggested. The final suggested system was verified the possibility through the placement. With this, i will offer effective measures which is more convenient to use and reliable.

• 패션비즈니스
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• 제21권3호
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• pp.14-28
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• 2017

This purpose of this study to analyze effect material properties have on change in QR code recognition rate according to change of materials by comparing recognition rate of color QR code. QR code applied to textile materials has the advantage of being washable and being applicable to lost child prevention goods or clothes or a person with dementia through record of information relating to the material or input of additional information, differently from QR code printed on the conventional paper. An effective method of entering QR code in textile materials is Digital Textile Printing(DTP), that facilitates printing by rapidly applying diverse information, and small quantity production. It is possible to tailor various QR codes according to use. Regarding samples to use, cotton material used in clothing products and Tyvek material recently applied to clothing and related products were selected. Reactive dyes were used for cotton, pigment was used for Tyvek, and QR code was printed with an inkjet printer by direct printing method. Printing methods and surface textures are different between cotton and Tyvek. It was revealed that consequent print results and results of recognition rate were different. Regarding color to be printed, 2015 S/S - 2017 S/S color presented by Pantone was used. Color combination affected recognition rate of color QR code. Understanding color combination, material properties and print characteristics may be helpful in increasing recognition rate of color QR code, and may contribute to usability of color QR code applied to textile materials in the future.

• 생약학회지
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• 제51권1호
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• pp.70-77
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• 2020

Mentha arvensis is used traditional medicine to treat various disorders. In the present study, M. arvensis were extracted by the solid-phase microextraction (SPME) method and analyzed by gas chromatograph-mass spectrometry (GC-MS). We investigated the protective effects and mechanisms of a M. arvensis extract on scopolamine-induced cognitive and memory impairment. Mice were orally pretreated with a M. arvensis extract or normal saline, and then behavior tests were conducted 30 min after scopolamine injection. The antioxidant capacities were analyzed by free radical scavenging (DPPH and ABTS). Acetylcholinesterase (AChE) activity were also measured using Ellman's method ex vivo test. In behavior tests, percent of spontaneous alteration, escape latency and swimming time in target quadrant were improved by the administration of the M. arvensis extract, which suggests that the M. arvensis extract improves memory function in the scopolamine-treated mice model. In addition, M. arvensis extract showed inhibition of the free radical and AChE activity. The results of the present study suggest that the M. arvensis extract ameliorates scopolamine-induced cognitive and memory deficits through the inhibition of free radicals and AChE activity. Therefore, M. arvensis may be a promising neuroprotective agent for management of learning and memory improvements in human dementia patients.