• Title/Summary/Keyword: Diffusion outcomes

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Information Intervention: A Taxonomy & Typology for Government Communication

  • Arceneaux, Phillip
    • Journal of Public Diplomacy
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    • v.1 no.1
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    • pp.5-35
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    • 2021
  • Where government communication in the early 20th century fell under the umbrella term, "propaganda," the post-WWII era saw a paradigm fracture into public affairs for domestic audiences, public diplomacy for foreign audiences, and psychological operations for hostile audiences. The continued diffusion of the Internet, however, has blurred such distinctions, mending this fractured paradigm. Based on in-depth interviews, this study typologizes government communication to contextualize how various tactics functions within the 21st century digital media ecology, through an "Information Intervention" taxonomy. In an age where state-sponsored disinformation and computational propaganda are tantamount threats, this paper elucidates the field's fundamental concepts by articulating who communicates with what audience, in what manner, with what intent, and with what desired outcomes.

Recanalization Rate and Clinical Outcomes of Intravenous Tissue Plasminogen Activator Administration for Large Vessel Occlusion Stroke Patients

  • Min-Hyung Lee;Sang-Hyuk Im;Kwang Wook Jo;Do-Sung Yoo
    • Journal of Korean Neurosurgical Society
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    • v.66 no.2
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    • pp.144-154
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    • 2023
  • Objective : Stroke caused from large vessel occlusion (LVO) has emerged as the most common stroke subtype worldwide. Intravenous tissue plasminogen activator administration (IV-tPA) and additional intraarterial thrombectomy (IA-Tx) is regarded as standard treatment. In this study, the authors try to find the early recanalization rate of IV-tPA in LVO stroke patients. Methods : Total 300 patients undertook IA-Tx with confirmed anterior circulation LVO, were analyzed retrospectively. Brain computed tomography angiography (CTA) was the initial imaging study and acute stroke magnetic resonance angiography (MRA) followed after finished IV-tPA. Early recanalization rate was evaluated by acute stroke MRA within 2 hours after the IV-tPA. In 167 patients undertook IV-tPA only and 133 non-recanalized patients by IV-tPA, additional IA-Tx tried (IV-tPA + IA-Tx group). And 131 patients, non-recanalized by IV-tPA (IV-tPA group) additional IA-Tx recommend and tried according to the patient condition and compliance. Results : Early recanalization rate of LVO after IV-tPA was 12.0% (36/300). In recanalized patients, favorable outcome (modified Rankin Scale, 0-2) was 69.4% (25/36) while it was 32.1% (42/131, p<0.001) in non-recanalized patients. Among 133 patients, non-recanalized after intravenous recombinant tissue plasminogen activator and undertook additional IA-Tx, the clinical outcome was better than not undertaken additional IA-Tx (favorable outcome was 42.9% vs. 32.1%, p=0.046). Analysis according to the perfusion/diffusion (P/D)-mismatching or not, in patient with IV-tPA with IA-Tx (133 patients), favorable outcome was higher in P/D-mismatching patient (52/104; 50.0%) than P/D-matching patients (5/29; 17.2%; p=0.001). Which treatment tired, P/D-mismatching was favored in clinical outcome (iv-tPA only, p=0.008 and IV-tPA with IA-Tx, p=0.001). Conclusion : The P/D-mismatching influences on the recanalization and clinical outcomes of IV-tPA and IA-Tx. The authors would like to propose that we had better prepare IA-Tx when LVO is diagnosed on initial diagnostic imaging. Furthermore, if the patient shows P/D-mismatching on MRA after IV-tPA, additional IA-Tx improves treatment results and lessen the futile recanalization.

A Model and Its Application of Performance Monitoring, Evaluation, and Management System for National R&D (국가연구개발 성과추적평가관리 시스템 모형 및 활용)

  • Kim, Moon-Soo;Lee, Hak-Yeon;Choi, Chang-Woo;Lee, Seong-Ryong;Choi, Kyung-Il;Jeon, Jin-Woo
    • Journal of Korea Technology Innovation Society
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    • v.11 no.4
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    • pp.613-638
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    • 2008
  • The Korean government established 'the Act on Performance Evaluation and Management for National Research & Development (R&D) Programs' in 2005, and one year later constructed a master plan, 'A Basic Plan for the Management and Utilization of R&D performance' that focused on better diffusing the public R&D outcomes. In this study we propose a model of performance monitoring, evaluation, and management system for national R&D, which is based on a systematic approach and the logic model that has been prevalently used in planning and evaluating the public programs, to meet the purpose of the law and the master plan as well as to facilitate the diffusion of national R&D outcomes focused mainly on the industrial application technology. Furthermore, in order to use the model for the several applications, the model's specific measures which includes the quantitative methodologies such as analytic hierarchy process (AHP) and data envelopment analysis (DEA) are suggested in accordance with the existing system of the evaluation institution in Korea.

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Surgical Outcomes of Cardiac Myxoma Resection Through Right Mini-Thoracotomy

  • Changwon Shin;Min Ho Ju;Chee-Hoon Lee;Mi Hee Lim;Hyung Gon Je
    • Journal of Chest Surgery
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    • v.56 no.1
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    • pp.42-48
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    • 2023
  • Background: With recent advances in cardiac surgery through minimal access, mini-thoracotomy has emerged as an excellent alternative for cardiac myxoma resection. This study analyzed the surgical results of this approach, focusing on postoperative cerebral embolism and tumor recurrence. Methods: We retrospectively reviewed 64 patients (mean age, 56.0±12.1 years; 40 women) who underwent myxoma resection through mini-thoracotomy from October 2008 to July 2020. We conducted femoral cannulation and antegrade cardioplegic arrest in all patients. Patient characteristics and perioperative data, including brain diffusion-weighted magnetic resonance imaging (DWI) findings, were collected. Medium-term echocardiographic follow-up was performed. Results: Thirteen patients (20.3%) had a history of preoperative stroke, and 7 (11.7%) had dyspnea with New York Heart Association functional class III or IV. Sixty-one cases (95.3%) had myxomas in the left atrium. The mean cardiopulmonary bypass and cardiac ischemic times were 69.0±28.6 and 34.1±15.0 minutes, respectively. Sternotomy conversion was not performed in any case, and 50 patients (78.1%) were extubated in the operating room. No early mortality or postoperative clinical stroke occurred. Postoperative DWI was performed in 32 (53%) patients, and 7 (22%) showed silent cerebral embolisms. One patient underwent reoperation for tumor recurrence during the study period; in that patient, a genetic study confirmed the Carney complex. Conclusion: Mini-thoracotomy for cardiac myxoma resection showed acceptable clinical and neurological outcomes. In the medium-term echocardiographic follow-up, reliable resection was proven, with few recurrences. This approach is a promising alternative for cardiac myxoma resection.

Reactor core analysis through the SP3-ACMFD approach Part II: Transient solution

  • Mirzaee, Morteza Khosravi;Zolfaghari, A.;Minuchehr, A.
    • Nuclear Engineering and Technology
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    • v.52 no.2
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    • pp.230-237
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    • 2020
  • In this part, an implicit time dependent solution is presented for the Boltzmann transport equation discretized by the analytic coarse mesh finite difference method (ACMFD) over the spatial domain as well as the simplified P3 (SP3) for the angular variable. In the first part of this work we proposed a SP3-ACMFD approach to solve the static eigenvalue equations which provide the initial conditions for temp dependent equations. Having solved the 3D multi-group SP3-ACMFD static equations, an implicit approach is resorted to ensure stability of time steps. An exponential behavior is assumed in transverse integrated equations to establish a relationship between flux moments and currents. Also, analytic integration is benefited for the time-dependent solution of precursor concentration equations. Finally, a multi-channel one-phase thermal hydraulic model is coupled to the proposed methodology. Transient equations are then solved at each step using the GMRES technique. To show the sufficiency of proposed transient SP3-ACMFD approximation for a full core analysis, a comparison is made using transport peers as the reference. To further demonstrate superiority, results are compared with a 3D multi-group transient diffusion solver developed as a byproduct of this work. Outcomes confirm that the idea can be considered as an economic interim approach which is superior to the diffusion approximation, and comparable with transport in results.

Clinical characteristics and outcomes in patients with lesion-positive transient ischemic attack

  • Kang, Su-Jeong;Lee, Sang-Gil;Yum, Kyu Sun;Kim, Ji-Seon;Lee, Sung-Hyun;Lee, Sang-Soo;Shin, Dong-Ick
    • Journal of Biomedical and Translational Research
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    • v.19 no.4
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    • pp.110-115
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    • 2018
  • Transient ischemic attack (TIA) indicates high risk for major stroke and is considered a medical emergency. Diffusion-weighted imaging (DWI) enables detection of acute ischemic lesions. The clinical significance of DWI positive lesions in TIA is obscure and its prevalence, clinical features are not established. Therefore, we performed a clinical, etiological and prognostic analysis through a cross-sectional analysis of 235 TIA patients, grouped according to presence of DWI lesion. Clinical features, underlying risk factors for stroke, outcome and rate of recurrence were analyzed. 3 months follow-up of modified Rankin Scales (mRS) were done with telephone survey. DWI positive lesions were present in 14.0% of patients. Etiological factors significantly associated with DWI lesions in TIA patients were male sex (p = 0.038), stroke history (p = 0.012) and atrial fibrillation (p < 0.001). Presence of at least one medium or high risk of cardioembolism from TOAST classification were not associated with lesions when excluding association to atrial fibrillation (p = 0.108). Clinical features showed no significant difference. Whether the patients had lesion-positive DWI was not related to an increase in mRS score during the hospital stay or at the 3-month follow-up after discharge. Future studies should include multi-center samples with large numbers, considering each unique medical environment. Routine acquisition of follow-up DWI for proper evaluation of the tissue-based definition of TIA should also be considered.

Complete Recovery of Perfusion Abnormalities in a Cardiac Arrest Patient Treated with Hypothermia: Results of Cerebral Perfusion MR Imaging

  • Kim, Min Jeong;Park, Yae Won;Lim, Soo Mee
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.1
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    • pp.56-60
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    • 2018
  • Therapeutic hypothermia in cardiac arrest patients is associated with favorable outcomes mediated via neuroprotective mechanisms. We report a rare case of a 32-year-old male who demonstrated complete recovery of signal changes on perfusion-weighted imaging after therapeutic hypothermia due to cardiac arrest. Brain MRI with perfusion-weighted imaging, performed three days after ending the hypothermia therapy, showed a marked decrease in relative cerebral blood flow (rCBF) and delay in mean transit time (MTT) in the bilateral basal ganglia, thalami, brain stem, cerebellum, occipitoparietal cortex, and frontotemporal cortex. However, no cerebral ischemia was not noted on diffusion-weighted imaging (DWI) or fluid-attenuated inversion recovery (FLAIR) sequences. A follow-up brain MRI after one week showed complete resolution of the perfusion deficit and the patient was discharged without any neurologic sequelae. The mechanism and interpretation of the perfusion changes in cardiac arrest patients treated with therapeutic hypothermia are discussed.

The Program Evaluation and Analysis of Creative Research Initiatives (창의적연구진흥사업 사업평가 및 분석)

  • 변명문
    • Journal of Technology Innovation
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    • v.12 no.1
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    • pp.161-188
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    • 2004
  • The objective of this research is to evaluate the Creative Research Initiative Program (CRI), a national R&D program funded by the Ministry of Science & Technology in Korea. The evaluation of CRI covers the following research questions; 1) Have it set a unique position and characteristic distinguished from other government-funded R&D programs\ulcorner 2) Are the achievements of the program relevant to its goal\ulcorner 3) What is its performances and how much is it achieved its goal\ulcorner The results are the followings; 1) CRI is perceived as a pure basic research, distinguished from other national basic research programs, such as the Coal Oriented Basic Research Program and the SRC and ERC. 2) CRI is a well-adapted R&D program in confront of the environmental changes and R&D needs, as well as follows the planned R&D areas. 3) CRI have performed well in the raising-up world-class research leaders and the nation-wide diffusion of creative R&D culture, while it got few performances in the overcoming the limitation of the existing technologies and the independent development of original key technologies for future industries. However, the duration of the program, 5 year, is too short to expect concrete outcome, such as creating original technologies. Many of the outcomes of CRI gets a lot of attention from top class scientists in the world, it is expected to generate various R&D performances in the future.

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The Role of Rural Revitalization Support Centers in Facilitating Community Innovation in Korea (지역사회 혁신을 촉진하기 위한 농촌활성화지원센터의 역할)

  • Im, Sang Bong
    • The Korean Journal of Community Living Science
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    • v.25 no.1
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    • pp.39-49
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    • 2014
  • This study identifies the necessity and importance of innovation in rural communities and highlights the role of rural revitalization support centers in facilitating the diffusion of community innovation. The study provides a literature review and employs the survey method to verify the arguments. There is an urgent need for rural communities to be distinct, attractive, and competitive in the wake of globalization. It is clear that they must recognize the need to facilitate innovation under growing trends toward trade liberalization, environment-oriented life styles, diversified consumer needs, and a knowledge-based society. The results provide support for the legitimacy of establishing rural revitalization support centers to help community leaders and local stakeholders develop their communities. More specifically, rural communities should employ R&D outcomes from diverse fields and capacity building by community members, leaders, and local governments to foster sustainable growth by overcoming limitations in spatial access and resources. The results suggest that rural revitalization support centers can be established as intermediary organizations that can be operated to facilitate community innovation in rural development. In addition, these centers should play key roles such as empowering communities, facilitating region-specific rural development policies, motivating R&D applications for rural development, encouraging rural development networks. Further, close attention should be paid to facilitate mutual learning by expanding networks and interactions between these centers.

Management Scheme According to Characteristics of PM-10 Occurred from Large Scale Development Site (대규모 단지조성 미세먼지 관리 방안)

  • Kwon, Woo-Taeg;Lee, Woo-Sik;Hong, Sang-Pyo
    • Journal of Environmental Impact Assessment
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    • v.22 no.1
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    • pp.79-87
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    • 2013
  • The purpose of this study is to establish PM-10 management manual for developing large scale sites by assessing the status of PM-10 reduction at ongoing large scale development sites. After analyzing the meteorological conditions and air quality characteristics of Sihwa MTV development site, ISCST3 (Industrial Source Complex Short Term Model 3) was implemented to predict PM-10 generation. The outcomes of ISCST3 modelling were utilized for verification of site survey data. As a result of applying air pollution modeling, the diffusion rate of PM-10 decreases according as the wind speed decreases. And the emission rate of PM-10 increase is linear to the concentration of PM-10. The reduction target of PM-10 can be derived quantitatively from the difference between the forecasted emission rate and the permissible emission limit of PM-10. The assessment of PM-10 characteristics which is deduced from ISCST3 and site survey can be practically applied to accomplish environmentally acceptable air quality manual for large scale development sites.