• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.13
• /
• pp.5487-5492
• /
• 2014

Ultrasonography is non-invasive and can give useful clues in the diagnosis of cervical lymphadenopathy, However, differential diagnosis is difficult in some situations even combined with color Doppler imaging. The present study was conducted to evaluate the clinical value of real time elastography in patients with unexplained cervical lymphadenopathy using a quantitative method. From May 2011 to February 2012, 39 enlarged lymph nodes from 39 patients with unexplained cervical lymphadenopathy were assessed. All the patients were examined by both B-mode ultrasound, color Doppler flow imaging and elastography. The method of analyzing elasto-graphic data was the calculation of the 10 parametres ("mean", "sd", "area%", "com", "kur", "ske", "con", "ent", "idm", "asm") offered by the software integrated into the Hitachi system. The findings were then correlated with the definitive tissue diagnosis obtained by lymph node dissection or biopsy. Final histology revealed 10 cases of metastatic lymph nodes, 11 cases of lymphoma, 12 cases of tuberculosis and 6 cases of nonspecific lymphadenitis. The significant distinguishing features for conventional ultrasound were the maximum short diameter (p=0.007) and absent of echogenic hilum (p=0.0293). The diagnostic accuracy was 43.6% (17/39 cases) and there were 17 patients with equivocal diagnosis. For elastography, "mean" (p=0.003), "area%" (p=0.009), "kurt" (p=0.0291), "skew" (p=0.014) and "cont" (p=0.012) demonstrated significant differences between groups. With 9 of the 17 patients with previous equivocal diagnoses (52.9%) definite and correct diagnoses could be obtained. The diagnostic accuracy for conventional ultrasound combined elastography was 69.2% (27/39 cases). There were differences in the diagnostic sensitivity of the two methods (p=0.0224). Ultrasound combined with elastography demonstrated higher rates of conclusive and accurate diagnoses in patients with unexplained cervical lymphadenopathy than conventional ultrasound. The quantitative program showed good correlation with the pathology of different lymph node diseases.

• Asian-Australasian Journal of Animal Sciences
• /
• v.30 no.7
• /
• pp.1037-1047
• /
• 2017

Objective: Despite an increasing number of investigations into the pathophysiology of necrotic enteritis (NE) disease, etiology of NE-associated diseases, and gene expression profiling of NE-affected tissues, the microRNA (miRNA) profiles of NE-affected poultry have been poorly studied. The aim of this study was to induce NE disease in the genetically disparate Fayoumi chicken lines, and to perform non-coding RNA sequencing in the intestinal mucosal layer. Methods: NE disease was induced in the Fayoumi chicken lines (M5.1 and M15.2), and non-coding RNA sequencing was performed in the intestinal mucosal layer of both NE-affected and uninfected chickens to examine the differential expression of miRNAs. Next, quantitative real-time polymerase chain reaction (real-time qPCR) was performed to further examine four miRNAs that showed the highest fold differences. Finally, bioinformatics analyses were performed to examine the four miRNAs target genes involvement in the signaling pathways, and to examine their interaction. Results: According to non-coding RNA sequencing, total 50 upregulated miRNAs and 26 downregulated miRNAs were detected in the NE-induced M5.1 chickens. While 32 upregulated miRNAs and 11 downregulated miRNAs were detected in the NE-induced M15.2 chickens. Results of real-time qPCR analysis on the four miRNAs (gga-miR-9-5p, gga-miR-20b-5p, ggamiR-196-5p, and gga-let-7d) were mostly correlated with the results of RNAseq. Overall, ggamiR-20b-5p was significantly downregulated in the NE-induced M5.1 chickens and this was associated with the upregulation of its top-ranking target gene, mitogen-activated protein kinase, kinase 2. Further bioinformatics analyses revealed that 45 of the gene targets of gga-miR-20b-5p were involved in signal transduction and immune system-related pathways, and 35 of these targets were predicted to interact with each other. Conclusion: Our study is a novel report of miRNA expression in Fayoumi chickens, and could be very useful in understanding the role of differentially expressed miRNAs in a NE disease model.

• Journal of Distribution Research
• /
• v.7 no.1
• /
• pp.61-86
• /
• 2002

The number of people who perform their banking business on Internet has been increasing drastically during the recent period and the trend still continues. Banks and other types of financial institutions are now competing intensely with each other in attracting customers to this new innovative banking service. The marketers in charge of formulating and implementing the strategies for this new banking business need to understand the behavioral factors as well as the technical factors in order to succeed in attracting more customers to this new service. products. A deep understanding as to why and how the customers are adopting the new service developed on information technology is a prerequisite for a successful marketing effort. The purpose of this dissertation is to find out what factors are playing important roles in the customers'decision related to the adoption of the Internet banking services. The focus of the research is threefold. First. by testing the hypotheses proposed by the Technology Adoption Model, a well-known theory in the IT-related behavioral science, an analysis was made as to which factors are more important in affecting the attitudes and adoption of the Internet banking on the part of customers. Secondly, an analysis was made as to whether the three criteria of the Technographics- -the attitude toward new technology, level of income, and the motivational factor- -are useful as the criteria for segmenting the Korean users of the online banking. Thirdly, an analysis was made as to whether each customer group segmented by the criteria of the Technographics reveal a differential decision process and thus requires a differential approach strategywise.

• Journal of Internet Computing and Services
• /
• v.20 no.4
• /
• pp.21-27
• /
• 2019

Selection of feature pattern gathered from the observation of the RNA sequencing data (RNA-seq) are not all equally informative for identification of differential expressions: some of them may be noisy, correlated or irrelevant because of redundancy in Big-Data sets. Variable selection of feature pattern aims at differential expressed gene set that is significantly relevant for a special task. This issues are complex and important in many domains, for example. In terms of a computational research field of machine learning, selection of feature pattern has been studied such as Random Forest, K-Nearest and Support Vector Machine (SVM). One of most the well-known machine learning algorithms is SVM, which is classical as well as original. The one of a member of SVM-criterion is Support Vector Machine-Recursive Feature Elimination (SVM-RFE), which have been utilized in our research work. We propose a novel algorithm of the SVM-RFE with Q-learning in reinforcement learning for better variable selection of feature pattern. By comparing our proposed algorithm with the well-known SVM-RFE combining Welch' T in published data, our result can show that the criterion from weight vector of SVM-RFE enhanced by Q-learning has been improved by an off-policy by a more exploratory scheme of Q-learning.

• Journal of Navigation and Port Research
• /
• v.43 no.1
• /
• pp.42-48
• /
• 2019

The significance of PNT information in the fourth industrial revolution is viewed differently in relation to the past. Autonomous vehicles, autonomous vessels, smart grids, and national infrastructure require sustainable and reliable services in addition to their high precision service. Satellite navigation system, which is the most representative system for providing PNT information, receive signals from satellites outside the earth so signal reception power is low and signal structures for civilian use are open to the public. Therefore, it is vulnerable to intentional and unintentional interference or hacking. Satellite navigation systems, which can easily acquire high performance of PNT information at low cost, require alternatives due to its vulnerability to the hacking. This paper proposed R-Mode (Ranging Mode) technology that utilizes currently operated navigation and communication infrastructure in terms of Signals of OPportunity (SoOP). For this, the Nationwide Differential Global Navigation Satellite System (NDGNSS), which currently gives a service of Medium Frequency (MF) navigation signal broadcasting, was used to validate the feasibility of a backup infrastructure in domestic maritime areas through simulation analysis.

• The Korean Journal of Emergency Medical Services
• /
• v.3 no.1
• /
• pp.65-76
• /
• 1999

Objectives: This study sought to examine the impact of alcohol use and misuse on mortality in korea during the 1991-l997. Methods: Alcohol-Related Disease Impact estimation software and Korea vital statistics data were used to calculate alcohol related-mortality, mortality rates, and YPLL(years of potential life lost). The major findings are as follows : An estimated 23,528 Korean died during 1997 from causes related to alcohol. Such deaths accounted for 17,052(12.60%) of all deaths for men and 6,206(5.88%) for women. Motor vehicle accidents were major contributors to the total estimated number of alcohol related deaths and years of potential life lost before age 65. Alcohol related mortality rates were significantly higher for men. For men, major causes of the deaths were motor vehicle accidents(4,147 deaths, 17.90 per 100,000 population), cancer of the stomach(1,467 deaths, 16.60 per 100,000 population) and chronic liver diseases and cirrhosis(1,233 deaths, 13.10). For women, the largest contributors to alcohol related mortality were motor vehicle accidents(1,509 deaths, 6.61), cerebrovascular diseases(1,114 deaths, 11.3) and cancer of the stomach(810 deaths, 8.24). Kleinman's method was used for obtaining on regional(Dongs, ups and Myons) differential of the alcohol related mortality in 1995. In general, The alcohol-related death rate for men was significantly higher than that for women, and the rate for ups and myons was significantly higher than that for dongs During 1997, approximately 356,667(male: 282, 510, female: 74, 157)YPLL to age 65 and 572,708(male:424,338, female:148,370)YPLL to life expectancy were attributable to alcohol related causes. Men accounted for 79% of the total YPLL to age 65 and 74% of the total YPLL to life expectancy The major contributors to these alcohol related years lost were the diagnostic categories of unintentional injuries. Particullary, In male, Motor vehicle accidents and accidental drowning-YPLL are considerably higher for other causes. Male-female YPLL differentials were greatest for mental disorder. Male-female mean-YPLL to age 65, accidental drowning(male;36.47, female;37.67) is higher for other causes. In both sexes, The YPLL and M-YPLL to life expectancy was significantly higher than the YPLL and M-YPLL to life expectancy.

• Journal of dental hygiene science
• /
• v.2 no.1
• /
• pp.1-9
• /
• 2002

The objection of this present study are (1) measurement of patient's expectation toward quality care of dental services. (2) Analysis of differential expectation of dental service by the patient characteristics and (3) presentation of measurement implication for better dental service at the dental clinic. The data used in the study were collected from April 25 to June 9, 2001 and for 77 patients of university dental hospital and 102 patients of dental clinic. The study found, in general, that patient's expectation on the clinic environmental factor was most highly scored followed by dental human factors. The convenience of transportation from the patient's residence to the clinic was highly concerned as be an important factor in dental service utilization.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.21 no.6
• /
• pp.625-633
• /
• 2020

this study, an expert AHP questionnaire analysis of public and private groups was conducted to take into consideration the requirements for realistic disaster services. Considered are public areas that manage disasters like fires and earthquakes that can be a major threat to national safety, as well as private areas that mainly develop disaster-related technologies. In the questionnaire, the public respondents valued accurate disaster situation information (ranked 4th and 6th) for citizens (1st), managers (3rd), and related organizations (2nd); the private sector highly valued the importance of three-dimensional (3D) control (ranked 1st, 3rd, and 5th) using future technologies. This study suggests the realization of a disaster-response service that meets the needs of public safety and technological innovation based on a 3D safety state information platform. We anticipate that this study will provide useful data for applying technology and for establishing detailed scenarios during the test bed and commercialization phases. We also expect that further studies will be conducted, such as the practical application and operation of realistic disaster response services, on the financial resources for the proliferation of local governments, and on policy support measures.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.29 no.8A
• /
• pp.879-888
• /
• 2004

In this paper, we propose a real time QoS(Quality of Service) guaranteed transmission mechanism for MPEG video traffic at the congested node in IP based networks. Recent spread of the Internet has increased the demands of a real time multimedia service of the quality, Because the type of Internet services can, however, offer the best effort delivery strategies, it is difficult to treat all the types of traffic with differential COS (Class of Service). Most of all, the hierarchical coding method of MPEG data utilizes the reference frame for the motion prediction. The loss of the reference frames makes QoS of the video traffic degraded because the reference frame bit error causes the consecutive packet loss. Therefore we have studied the real time QoS guaranteed mechanism for video traffic by analyzing the previous methods. Computer simulation results show that the proposed scheme has better performance than the previous one.

• Korean Journal of Adult Nursing
• /
• v.25 no.6
• /
• pp.622-632
• /
• 2013

Purpose: This study was conducted to compare the nurse licensure examination system in Korea with that of the United States (US). Methods: Focus interviews with the administrative staff of the National Council of State Boards of Nursing (NCSBN) were held. two areas were explored in the interviews: the item development process and the general administrative operating procedures. Results: NCLEX-RN items are designed for entry-level practice. The items are subjected to a series of 12 steps including a item writing panel, a content and editorial review, a sensitivity panel, a pre-test, a Differential item functioning panel and a committee review. NCSBN is responsible for the test for registered nurses and one for practical nurses. In contrast the Korean National Health Personnel Licensing Board (KNHPLB) is responsible for nursing is and 21 other health related licensure. Another difference is that in Korea there is no consistent and specialized staff to develop question items. Items are developed by educators who are not active nurses (this last statemtne is not a finding but a point of view usually not given in findings.). Conclusion: Korean nurses form the largest group of health related job categories and the most direct to health care consumers. Therefore, the nursing licensure exam should be acknowledged as the most influential licensure exam in health care services. We recommend a nursing specialized licensing institution to be established with active nurse' participation in item development process to reflect clinical practice into licensure exam.