• 대한전자공학회논문지TE
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• 제37권5호
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• pp.71-76
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• 2000

본 논문에서는 TC-16ADPSK(Trellis Coded-16 Amplitude Differential Phase Shift Keying)를 사용하여 데이터 량이 서로 다른 정보(Information)를 동시 전송하기 위한 방식을 제안한다. 제시한 시스템의 성능 분석은 부가적인 화이트 가우시언 잡음(AWGN : Addictive White Gaussian Noise) 채널과 레일라 이 페이딩(Rayleigh Fading) 채널에 대한 비트오율(Bit Error Rate)을 기준으로 한다. 제안한 방식은 정보량이 다른 두 가지 정보를 한 채널에 동시 전송하며 적은 량의 데이터는 Star-16APSK의 신호 격자중에 크기를 결정도록 매핑하고 다른 정보는 위상을 결정하는데 사용된다. 정보 데이터 검파시 ASK와 DPSK 다른 검파 방식을 사용하므로 통합된 정보가 쉽게 분리되며 한 채널에 각각 다른 정보를 효율적으로 전송이 가능하다. 매트랩 통신 툴박스를 사용하여 BER 성능 결과를 분석한 결과, 제안한 방식은 동일 SNR에 대해 서 그레이 코드를 사용한 경우가 0.5㏈-1.5㏈ 정도의 코딩 이득을 나타내었다.

• Asian-Australasian Journal of Animal Sciences
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• 제14권12호
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• pp.1670-1674
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• 2001

To understand molecular mechanisms that regulate deposition and release of intramuscular fat, a fasting-induced clone was identified by differential screening from cDNA library of adipose tissues of Korean cattle. The clone had a total length of 1,319 nucleotides coding for 334 amino acids. It was identified as one encoding L-lactate dehydrogenase H chain (LDH-B). Comparison of the deduced amino acid sequences of bovine LDH-B with those of pig, human, rat, and mouse showed 98%, 98%, 97%, and 96% identity, respectively. Food deprivation for 48 h increased mRNA levels of LDH-B gene in adipose tissues of Korean cattle compared to fed- and 6 h refed- tissues. The expression of obese mRNA was examined for individual adipose tissue from several fat depots. Fasting induced expression of LDH-B gene in subcutaneous adipose tissues, but it did not affect expression levels in abdominal, perirenal and intramuscular tissues. Results demonstrate that induction of LDH-B gene during fasting may represent a metabolic shift from anaerobic state to aerobic predominance in fasted adipose tissues and that its responses to fasting are different among several adipose tissues.

• Asian-Australasian Journal of Animal Sciences
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• 제31권1호
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• pp.13-18
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• 2018

Objective: Meat quality including muscle color in chickens is an important trait and continuous selective pressures for fast growth and high yield have negatively impacted this trait. This study was conducted to investigate genetic variations responsible for regulating muscle color. Methods: Whole genome re-sequencing analysis using Illumina HiSeq paired end read method was performed with pooled DNA samples isolated from two broiler chicken lines divergently selected for muscle color (high muscle color [HMC] and low muscle color [LMC]) along with their random bred control line (RAN). Sequencing read data was aligned to the chicken reference genome sequence for Red Jungle Fowl (Galgal4) using reference based genome alignment with NGen program of the Lasergene software package. The potential causal single nucleotide polymorphisms (SNPs) showing non-synonymous changes in coding DNA sequence regions were chosen in each line. Bioinformatic analyses to interpret functions of genes retaining SNPs were performed using the ingenuity pathways analysis (IPA). Results: Millions of SNPs were identified and totally 2,884 SNPs (1,307 for HMC and 1,577 for LMC) showing >75% SNP rates could induce non-synonymous mutations in amino acid sequences. Of those, SNPs showing over 10 read depths yielded 15 more reliable SNPs including 1 for HMC and 14 for LMC. The IPA analyses suggested that meat color in chickens appeared to be associated with chromosomal DNA stability, the functions of ubiquitylation (UBC) and quality and quantity of various subtypes of collagens. Conclusion: In this study, various potential genetic markers showing amino acid changes were identified in differential meat color lines, that can be used for further animal selection strategy.

• 조형예술학연구
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• 제8권
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• pp.129-159
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• 2005

Web sites have become one of most important factor for sales products as well as advertising communications in these days. So numerous web sites have been developed for corporations and brands. It is not easy to getting more attention as a prominent web site expression among various types of numerous web sites. Due to the voluminous expansion of visual communications and the change of the media. new advertising creative must be needed for serving to differentiate the message, inviting audiences to participate more positively in Web site communications. This thesis aims at reviewing images and semiotics for analyzing web sites. And this thesis is about the significations of web sites for some of supreme brands. Chapter I describes the aim of this thesis about the signification of web sites, especially concentrate on the intro-pages of worldwide supreme brands. such as Chanel, Louis Vuitton, Yves Saint Laurent, Prada, and Burberry. And Chapter II introduces the general concept of Image and Semiotics. Chapter III deals with the signification of the web sites with introducing semiotic methods such as the theory of R. Barthes. Chapter IV discusses the signification of Images of web sites as an advertising creative talking into consideration of semiotic theories. And this thesis analyze almost all visual images and verbal message by the theory of R. Barthes. In this matrix, a. particular image of web site can be analyzed into its basic structure of pictorial and word elements , i. e., into the representations the viewer uses and identifies. It's my belief that one of aesthetic engineering approaches such as Semantic Differential Method and semiotic approaches such as the Interpretant Matrix for advertising design images provide basic methods which is about defining the process of constructing and coding the advertising images as well as analyzing and decoding advertising expressions. So I suggest these kinds of studies on the images of web sites as well as advertising design images.

• Parasites, Hosts and Diseases
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• 제35권3호
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• pp.203-210
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• 1997

이질아메바 병원성 분리주에서 특이적으로 발현되는 mRNA를 동정하고자 differential display reverse transcription-polymerase chain reaction(DDRT-PCR)을 수행하여 병원성 특이 증폭산물을 확인하였다. 한국인에서 검출한 이질아메바 병원성 분리주 YS-27과 Entamoeba dispar분리주인 S 16으로부터 정제한 mRAN를 주형으로 11개의 arbitrary primer와 3개의 one base anchored $oligo-dT_{11}M$(M: A, C 또는 G)의 조합을 이용, DDRT-PCR을 실시한 결과 31개의 분획이 YS-27주에서만 증폭된 것으로 확인되었다. 이 331개 DNA 중 21개는 cysteine proteinase 유전자와 상동성을 나타내었다. YS-27주로부터 제작된 cDNA library를 나머지 DNA를 탐침으로 사용, 검색하여 최종 4개의 clone을 얻었다. 이 4개의 clone을 이용, immunoscreening을 수행한 결과, 이 clone들은 이질아메바 감염자 혈청과 양성반응을 나타내고 있었다.

• Journal of Biosystems Engineering
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• 제17권1호
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• pp.65-78
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• 1992

When using a computer vision system for a measurement, the geometrically distorted input image usually restricts the site and size of the measuring window. A geometrically distorted image caused by the image sensing and processing hardware degrades the accuracy of the visual measurement and prohibits the arbitrary selection of the measuring scope. Therefore, an image calibration is inevitable to improve the measuring accuracy. A calibration process is usually done via four steps such as measurement, modeling, parameter estimation, and compensation. In this paper, the efficient error calibration technique of a geometrically distorted input image was developed using a neural network. After calibrating a unit pixel, the distorted image was compensated by training CMLAN(Cerebellar Model Linear Associator Network) without modeling the behavior of any system element. The input/output training pairs for the network was obtained by processing the image of the devised sampled pattern. The generalization property of the network successfully compensates the distortion errors of the untrained arbitrary pixel points on the image space. The error convergence of the trained network with respect to the network control parameters were also presented. The compensated image through the network was then post processed using a simple DDA(Digital Differential Analyzer) to avoid the pixel disconnectivity. The compensation effect was verified using known sized geometric primitives. A way to extract directly a real scaled geometric quantity of the object from the 8-directional chain coding was also devised and coded. Since the developed calibration algorithm does not require any knowledge of modeling system elements and estimating parameters, it can be applied simply to any image processing system. Furthermore, it efficiently enhances the measurement accuracy and allows the arbitrary sizing and locating of the measuring window. The applied and developed algorithms were coded as a menu driven way using MS-C language Ver. 6.0, PC VISION PLUS library functions, and VGA graphic functions.

• 한국통신학회논문지
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• 제19권5호
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• pp.901-911
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• 1994

직접 스펙트럼 확산(DS)방식과 주파수 도약 확산(FH)방식을 혼합시킨 하이브리드 DS/SFH-SSMA 시스템에 대해서 m-분포 페이딩 체널에서의 비동기 MDPSK 신호의 오율특성을 구하고, 다이버시티 기법과 부호화 기법을 함께 도입하였을때의 오율특성도 구했다. 얻은 결과로부터 페이딩의 심도 m에 따른 오율성능의 열화 정도를 알 수 있었는데 레일리 페이딩 환경(m=1)에서는 도약 주파수를 증가시키면 hit될 확률이 감소하므로 다중접속에 의한 간섭의 영향이 감소하고, 호핑수(q)가 사용자수(K)보다 무척 크고, 비트 에너지 대 잡음 전력비(E/N)가 높을때는 다중접속에 의한 간섭은 무시되어 다중경로에 의한 영향이 지배적이 된다는 것과, 비트 에너지 대 잡음 전력비가 낮을때는 가우스 잡음의 영향이 지배적이 되어 호핑수(q)에 관계없이 오율성능이 일정해진다는 것을 알았다.

• 한국통신학회논문지
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• 제17권9호
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• pp.939-950
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• 1992

Collision-free 전송(傳送) 가능성과 2차 다중(多重) 접속 간섭(干涉)의 영향면에서 다중(多重) 캡쳐 수신기(受信機)를 사용한 단일확산(單一擴散)코드 방식의 성능(性能)이 송신기별(送信機別)(T/O) 코드분할 다중(多重)접속(CDMA) 방식(方式)의 성능(性能)과 비교(比較)된다. 성능비교(性能比較)를 위해, 단일(單一)코드 방식(方式)과 완전한 collision-free 전송(傳送)을 보장하는 T/O CDMA 방식(方式)에 대해 다중(多重)접속 간섭(干涉)의 특징이 서술(敍述)된다. 백색(白色) 가우시안 잡음(雜音)하에서 직접(直接)시퀀스 차동(差動) 위상(位相)편이키잉 데이터 변조(變調)와 forward 에러정정부호화(訂正符號化)를 (BCH 코드) 사용한 위의 두방식(方式)에 대해 throughput 성능(性能)이 평가(評價)된다. 라디오의 수(數)가 비교적 많은 경우에, 적당한 신호대(信號對) 잡음화(SNR)에서 단일(單一)코드 방식(方式)이 T/O CDMA방식보다 최대(最大) throughput을 증가(增加)시킬 수 있음을 확인(確認)하였다.

• Genomics & Informatics
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• 제19권2호
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• pp.17.1-17.13
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• 2021

Breast cancer is one of the leading causes of cancer in women all over the world and accounts for ~25% of newly observed cancers in women. Epigenetic modifications influence differential expression of genes through non-coding RNA and play a crucial role in cancer regulation. In the present study, epigenetic regulation of gene expression by in-silico analysis of histone modifications using chromatin immunoprecipitation sequencing (ChIP-Seq) has been carried out. Histone modification data of H3K4me3 from one normal-like and four breast cancer cell lines were used to predict miRNA expression at the promoter level. Predicted miRNA promoters (based on ChIP-Seq) were used as a probe to identify gene targets. Five triple-negative breast cancer (TNBC)-specific miRNAs (miR153-1, miR4767, miR4487, miR6720, and miR-LET7I) were identified and corresponding 13 gene targets were predicted. Eight miRNA promoter peaks were predicted to be differentially expressed in at least three breast cancer cell lines (miR4512, miR6791, miR330, miR3180-3, miR6080, miR5787, miR6733, and miR3613). A total of 44 gene targets were identified based on the 3'-untranslated regions of downregulated mRNA genes that contain putative binding targets to these eight miRNAs. These include 17 and 15 genes in luminal-A type and TNBC respectively, that have been reported to be associated with breast cancer regulation. Of the remaining 12 genes, seven (A4GALT, C2ORF74, HRCT1, ZC4H2, ZNF512, ZNF655, and ZNF608) show similar relative expression profiles in large patient samples and other breast cancer cell lines thereby giving insight into predicted role of H3K4me3 mediated gene regulation via the miRNA-mRNA axis.

• Journal of Microbiology and Biotechnology
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• 제31권7호
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• pp.921-932
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• 2021

LINC01272 is a long non-coding RNA (lncRNA) that has been considered as a biomarker for many diseases including lung squamous cell carcinoma. Here, we investigated the function and mechanism of LINC01272 on lung cancer (LC). The differential expression of LINC01272 in LC and normal samples was analyzed by GEPIA based on the data from TCGA-LUAD database, as survival prognosis was analyzed through Kaplan-Meier Plotter. LINC01272 overexpression plasmid and miR-7-5p mimic were transfected into A549 and PC-9 cells. LINC01272, miR-7-5p and cardiolipin synthase 1 (CRLS1) mRNA expression was measured by quantitative reverse transcription-polymerase chain reaction. Cell viability was detected through MTT assay. Cell multiplication was evaluated by cell formation assay. Cell apoptosis was assessed through flow cytometry assay. Through bioinformatics, the target miRNA of LINC01272 and downstream genes of miR-7-5p were predicted. The targeting relationship was tested by dual luciferase reporter analysis. CRLS1, B-cell lymphoma-2 (Bcl-2), BCL2-associated X (Bax) and cleaved caspase-3 protein levels were detected through western blot. LINC01272 was downregulated in LC and low LINC01272 expression had poor prognosis. In A549 and PC-9 cells, LINC01272 inhibited cell viability and multiplication and induced apoptosis. LINC01272 negatively regulated miR-7-5p and CRLS1 was a target of miR-7-5p. MiR-7-5p reversed the effect of LINC01272 on viability, multiplication, apoptosis and expression of miR-7-5p and CRLS1 as well as apoptosis-related factors (Bcl-2, Bax and cleaved caspase-3). LINC01272 suppressed cell multiplication and induced apoptosis via regulating the miR-7-5p/CRLS1 axis in LC.