BACKGROUND/OBJECTIVE: The aim of this experiments was to show anti-obesity effects of Korean solar salt from different salt fields in diet-induced obese mice. MATERIALS/METHODS: Diet-induced obesity (DIO) was induced by a high-fat diet (HFD; 45% cal from fat) in C57BL/6J mice for eight weeks. The mice were fed with the designated diets (chow diet for Normal, HFD for Control, 0.47%-salt-mixed HFD for purified salt (PS), Guerande solar salt from France (SS-G), solar salt from Y salt field (SS-Y), solar salts from T salt field (SS-T) and S salt field (SS-S)) for another eight weeks. We checked body weight, food efficiency ratio (FER) and tissue weights (liver and epididymal adipose tissue (EAT)), and observed serum concentrations of triacylglycerol (TG), total cholesterol (TC), leptin and insulin. We also evaluated gene expressions of adipogenic / lipogenic mRNAs of $C/EBP{\alpha}$, $PPAR{\gamma}$ and FAS and beta-oxidation-related factors ($PPAR{\alpha}$ and CPT-1) in liver and EAT. The mineral composition of salt samples were analyzed using inductively coupled plasma optical emission spectrometry (ICP-OES). RESULTS: SS-T and SS-S significantly reduced body weight gain, FER, and weight of EAT compared to control and other samples (P < 0.05). SS-T and SS-S also significantly decreased serum levels of TG, TC, leptin and insulin (P < 0.05). SS-T and SS-S suppressed expressions of adipogenic / lipogenic mRNAs in liver and EAT, while promoting expression of beta-oxidation-related factors. The lowest sodium concentration was observed in SS-T ($30.30{\pm}0.59%$), and the lowest sodium-to-potassium (Na/K) ratio was found in SS-S (17.81). CONCLUSIONS: Our study shows that well-processed Korean solar salt may have anti-obesity effects in vivo, probably owing to its differences in mineral composition and other components, presumably resulting from the manufacturing processes. Further research is needed into the mechanism and to explore optimal manufacturing processes.
Purpose: Stem cells continue to receive research attention in the clinical fields, and adipose-derived stem cells (ADSCs) have been shown to be a good source raw material. Many plastic surgeons are researching the ADSC adipogenesis with a view of conducting clinical trials, and many attempts have been made to identify the factors that promote the adipogenesis of ADSCs, but comparatively few correlation studies have been undertaken to explore the relation between reactive oxygen species (ROS) and the ADSC adipogenesis. We undertook this study is to investigate the effects of ROS on ADSC adipogenesis. Methods: ADSCs were isolated and cultured from abdominal adipose tissue, and cultured in different media; 1) DMEM(control), 2) adipogenesis induction culture medium, 3) adipogenesis induction culture medium with ROS ($20{\mu}M/50{\mu}M\;H_2O_2$), 4) adipogenesis induction culture medium containing ROS ($20{\mu}M/50{\mu}M\;H_2O_2$) and antioxidant ($10{\mu}M/20{\mu}M$ Deferoxamine). We compared adipogenesis in these different media by taking absorbance measurements after Oil-Red O staining every 5 days. Results: After culturing for 20 days, significant differences were observed between these various culture groups. Absorbance results showed significantly more adipogenesis had occurred in media containing adipogenesis induction culture medium and $H_2O_2$ (in a $H_2O_2$ dose-dependently manner) than in media containing adipogenesis induction culture medium and no $H_2O_2$ (p<0.001). Furthermore, in media containing adipogenesis induction culture medium, $H_2O_2$, and antioxidant, absorbance results were significantly lower than in adipogenesis induction culture medium and $H_2O_2$ (p<0.001). Conclusion: These findings suggest that ROS promote the adipogenesis of ADSCs. We suggests that ROS could be used in the adipose tissue engineering to improve fat cell differentiation and implantable fat tissue organization.
The purpose of this study is to investigate daily lives of the intellectually disabled living in residential facilities. The daily time use method that monitors and records 24 hours of the subject was used for the analysis of daily lives of the institutionalized disabled and verbal interaction patterns within each facility. In particular, the analysis focused on 'frequency of activities' and 'lives', with the method of time budget. Based on the activity category table of the 2004 nationwide Time Use Survey, the analysis aimed to identify differences and similarities between the non-disabled and the disabled in terms of daily time use. The interaction pattern analysis method on grounds of the Flanders Category system(1963) indicates the level, the type, and the full details of interaction between the institutionalized disabled and the living rehabilitation teachers. This study is all the more significant in that it monitored the daily lives of the institutionalized disabled for the first time to allow in-depth understanding about the daily lives of the disabled; analyzed interaction patterns between the institutionalized disabled and living rehabilitation teachers; applied time budget study method, a frequently used one in adjacent fields, and therefore should serve as a valuable source material for future studies.
This study was conducted to evaluate the scouting methods for larva and adults of the alfalfa weevil, $Hypera$$postica$ Gyllenhal on Chinese milkvetch, $Astragalus$$sinicus$ L. in the field. Three sampling methods, shake-bucket, shake-picking, and a sweeping net were evaluated for collecting alfalfa weevil larvae. We found significant differences among scouting methods and date in all survey fields. Sweep-net sampling was less able to detect small larvae than large larvae, which were not detected until early April whereas the shake-bucket, and shake-picking methods efficiently collected larvae from middle March. A Pitfall trap with three different baits - no bait, kidney bean seeds and sprouting kidney beans were compared for collection efficiency of alfalfa weevil adults. Collection efficiencies were significantly different by bait(p<0.018). Traps baited with sprouting kidney beans were the most efficient for collecting the alfalfa weevil. The number of alfalfa weevil caught was not significantly different between kidney bean seed and no bait in the pitfall trap. Therefore, the shake-bucket method for larvae and a pitfall trap baited with sprouting kidney beans for adults are recommended for scouting of the alfalfa weevil in a Chinese milkvetch field.
Kim Ki-Chul;Park Sung-Jung;Jahng Doo-Sub;Kim Sam-Tae;Kim Yoo-Chul;Kwon So-Hee;Jung Hae-Kyoung;Song Yung-Sun;Lee Ki-Nam
Journal of Society of Preventive Korean Medicine
/
v.8
no.1
/
pp.19-32
/
2004
This study was conducted to evaluated musculoskeletal subjective symptoms and the degree of stress of industrial workers to present fundamental materials of preventive oriental medicine for improving their health and quality of life. During the medical examination with oriental medicine method, presence of subjective symptoms of musculoskeletal pain, Psychosocial Well-being Index(PWI) and life style were checked by using questionnaire method in 474 industrial workers. The collected data were analyzed with crosstabs, ANOVA and T-test. The results were as follows; 1. In general differences according to musculoskeletal subjective symptoms, education level of high school graduation had significantly higher distribution than that of below middle school or above university graduation in the pain present group. 2. In the musculoskeletal subjective symptoms and the degree of stress, all of Factor1, Factor2. Factor3, Factor4. and PWI had higher score in pain present group than in pain free group and the difference was statistically significant. 3. According to degree of stress and general character of subjects, single and education level of high school graduation had high score in Factor2, Factor3 and PWI. Factor1 and Factor3 was high in income group of low 1.49 million won. Factor2, Factor4, and PWI was high significantly in income group of 1.50 - 2.99 million won. In job type, manufacturing worker group had significantly high score in Factor3. 4. In degree of stress and life style difference, there was significant difference in PWI score in the field of alcohol chinking, smoking, exercise, obesity except sleeping hours. In the present study. as a result, it is found out that musculoskeletal subjective symptoms present group had higher score in psychosocial stress across the fields than symptom-free group and it is recommended that continuous studies on the relationship of job-related musculoskeletal disorders and psychosocial stress should be performed for improvement and prevention of mental and physical health of industrial worke
Han Jong-Min;Kwon So-Hee;Jung Hae-Kyoung;Kang Hong-Gu;Song Yung-sun;Lee Ki-Nam
Journal of Society of Preventive Korean Medicine
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v.8
no.1
/
pp.47-58
/
2004
This study was conducted to evaluated the degree of job-related life style and stress of industrial workers to present fundamental materials of preventive oriental medicine. The medical examination with oriental medicine method was performed from October 14 to November 1, 2002 for the 474 industrial workers and general characters, life style and Psychosocial Well-being Index(PWI) were collected by using self-recording type questionnaire. The results were as follows; 1) All 474 of subjects were male, job type was distributed into technician, 37.8% of them, white collar worker, blue collar worker, research worker in an orderly fashion. 2) As a result of comparison between the job types in general characters, research worker group was the highest in education level, above 10 years group in employee duration and 1.5-2.99 million won group in monthly income was the largest group in all job type and the distribution was significantly different. 3) Analyzing the difference in life style according to the job type shows that significantly highest prevalence of drinking alcohol was found in blue collar workers, they drank alcohol 2-4 times a week and that workers did not smoke in all group of job type and the prevalence of exercise was significantly high in less than 1 time a week. 4) Analyzing the difference in the degree of stress according to the job type shows that blue collar worker group had the highest score in Factor 1, Factor 4 fields, technician group had the highest score in Factor 2 field and the differences were significant. Considering above results, the present study shows that there are difference in life style and stress according to the job type in industrial workers and that health management according to job type must be required to improve health condition and to prevent disease of industrial workers in the future.
The purpose of this thesis is to discuss the characteristic methods of Mathematics Education. However, it is not simple to find the proper research method of Mathematics Education since Mathematics Education deals with the practice of teaching and learning mathematics, as well as the topics of scholarly research on the practice. Issues on Mathematics Education might vary with the epidemical aspects, which are basic attitudes toward the knowledge and understanding about Mathematics. Thus, this thesis will discuss two questions: First, What are the distinguishing characteristics of Mathematics Education as a field of study, when compared with ones of mathematics? Second, What are the characteristic methods of Mathematics Education, when compared with ones of other academic fields? For solving those questions, this thesis starts from meanings of science and education. And it also classifies Mathematics as formal science whereas Mathematics Education as social science by showing differences between Mathematics and Mathematics Education: research subject of Mathematics targets on mathematics itself and it uses the deductive method. On the other hand, Mathematics Education research handles the practice of mathematics of students and uses plausible reasoning. Also, it will also show why Mathematics Education shares lots of aspects with social science, not with natural science, which has many different characteristics from those of social science. Many researchers have agreed that Education should be categorized into the social science but misplaced Mathematics Education and Science Education into the natural science. It is true that physics and chemistry are natural science. And also it should be said that pure science is formal science. But it should be considered that just like Education, Mathematics Education and Science Education are in the category of social science.
The effect of polyethylene film(P.E.) mulching on the degradation of alachlor(N-methoxymethyl-2, 6-diethyl ${\alpha}-chloroacetoanilide$), pendimethalin(3, 4-dimethyl-2, 6-dinitro-N-l-ethylpropylanilide) and diphenamid(N,N-dimethyl-2, 2-diphenylacetamide) in red pepper, peanut, and sesame fields was investigated. In soils under the non-mulching condition the half-lives of alachlor, pendimethalin and diphenamid were 3, 37 and $24{\sim}46$ days, respectively. However, the half-lives of those under the P.E. mulching condition were longer than under the non-mulching condition. The differences in the half-lives between P.E. mulching and non-mulching conditions were about 30 days for pendimethalin and from 20 to 90 days for diphenamid. However, the half-life of alachlor was hardly affected by P.E. mulching. Pendimethalin and alachlor were not detected in the harvasted red peppers, peanuts and sesame under P.E. mulching and non-mulching conditions. But, the residue of diphenamid in peanuts was 0. 147 ppm under the P.E. mulching condition and 0.071 ppm under the non-mulching condition, and the residue of diphenamid in sesame was 0.022 ppm under the P.E. mulching condition and 0.129 ppm under the non-mulching condition. The amounts, however, were below the tolerance limits for pesticide residue.
The purpose of this study was to provide basic data necessary for educating dental hygiene students by establishing a desirable sense of ethics values. In this descriptive research, 97 dental hygiene students and 100 non-dental hygiene students (in other health related fields) from Daegu Gyeongbuk City were selected. Tools used for data analysis were descriptive statistics, t-test, one-way ANOVA, Scheffe test and correlation analysis with SPSS/WIN 17.0 version. Average scores for consciousness of biomedical ethics in dental hygiene students was 2.87, and in non-dental hygiene students, 2.82. When differences in the consciousness of biomedical ethics of dental hygiene and non-dental hygiene students were compared, dental hygiene students had significantly higher scores for prenatal diagnosis of fetus, right to life of newborn, right to life of fetus, brain death, artificial abortion, but significantly lower for organ transplantation. Variables which influenced consciousness of biomedical ethics were etihcal values in the dental hygiene students and intent to attend a class in biomedical ethics, quantity and quality of experience of hearing for biomedical ethics and religion in the non-dental hygiene students. Continuing educational programs need to be considered and attention given to the significant variables that can promote consciousness of biomedical ethics in dental hygiene students.
KIPS Transactions on Software and Data Engineering
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v.2
no.3
/
pp.187-194
/
2013
Recently, there have been many trials to analyze characteristics of research trends through a structural analysis of keyword networks in various fields. However, most previous studies have mainly focused on structural analysis harbored in some static networks and there is a lack of research on changes of such networks structure with time. In this paper, we constructed annual keyword networks by using a database of papers published in the international computer engineering-field journals from 2002 through 2011, and examined the changes of them. As a result, it was shown that most keywords in a network are preserved in the network of the next year, and their degree of connectivity and the average weight of the connections were higher and smaller, respectively, than those of the keywords which are not preserved. In addition, when a keyword network shifted to one of the next year, the connections between keywords were more likely to be removed than preserved, and the average weight of the removal connections was higher than that of the preserved ones. These results imply that the keywords are not changed over time but their connections are very likely to be changed; and there is apparent differences between the preserved and removal groups of keywords/connections with respect to degree and weights of connections. All these results are consistently observed over the ten-year datasets and they can be important principles in understanding the structural changes of the keyword networks.
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