• Clinical and Molecular Hepatology
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• v.24 no.4
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• pp.358-366
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• 2018

Severe acute alcoholic liver disease (SAAH) unresponsive to medical therapy shows one-year-mortality rates of up to 90%. Most transplant centers request six months of alcohol abstinence prior to transplantation, the so-called "6-month rule." This regulation is not based on strong evidence, repeatedly making it a topic of controversial debates. The majority of patients with SAAH will die before fulfilling the 6-month rule. Therefore, liver transplantation (LT) protocols are becoming more flexible towards the rigid abstinence regulation, especially concerning SAAH patients. We conducted a literature review regarding LT in SAAH and its outcomes, including post-transplant mortality and recidivism. We studied available data on PubMed from 2011 and onwards whilst including articles dealing with genetic components, medical therapy and historic snapshots of alcoholism. Emerging studies recommend LT in SAAH not responding to medical therapies even without realizing the required abstinence period, since the majority of these patients would die within 6 months. SAAH without response to medical therapy has one-year-mortality rates of up to 90%. The 6-month rule is not based on strong evidence and is repeatedly a topic of controversial debates. There is genetic linkage to alcoholism and medical therapy is not as effective as estimated, yet. The 6-months-regulation has not shown to evidently decrease the risk of recidivism post-LT, which is a lifesaving treatment in SAAH patients. Insisting on rigid sobriety rules results in excluding patients with a low risk of recidivism from being transplanted. Moreover, the genetic linkage of alcoholism must be recognized.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.11
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• pp.1848-1856
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• 2013

This study is designed to examine the change in physical properties of extruded brown rice-vegetable mix at different temperatures and $CO_2$ gas injections. Moisture content and screw speed were fixed to 27% and 100 rpm respectively. Die temperatures and $CO_2$ gas injections were adjusted to 60, 80, $100^{\circ}C$ and 0, 150 mL/min, respectively. The ratio of ${\alpha}$-brown rice, brown rice and sugars (oligosaccharides and palatinose) was fixed to 25, 50 and 16%, respectively. Green tea, tomato and pumpkin powder were blended individually at 9%. Specific mechanical energy (SME) input decreased as die temperature for each vegetable addition increased. All extrudates decreased in density and breaking strength, but increased in specific length and water soluble index as $CO_2$ gas injection increased. Elastic modulus decreased as the die temperature and $CO_2$ gas injection increased. Extruded green tea mix with $CO_2$ gas injection at 150 mL/min was larger pore size and higher amount of pore than the tomato and pumpkin extrudates with $CO_2$ gas injection. Cold extrusion with $CO_2$ gas injection at $60^{\circ}C$ die temperature could be applicable for making Saengsik (uncooked food).

• The Korean Society of Law and Medicine
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• v.23 no.2
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• pp.67-96
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• 2022

"Aid in Dying" means that when a decision-making patient suffers from an incurable disease, a drug that can speed up death is prescribed by a doctor and used to lead to death. Since the suspension of life-sustaining treatment was institutionalized based on human dignity and patient autonomy, the question of whether assisted death can be legally justified in relation to the right to receive medical help to shorten one's life to die with dignity has recently been actively discussed. In Korea, since the suspension of life-sustaining treatment was institutionalized by the enactment of the Life-sustaining Treatment Decision Act in 2016, an amendment to the Life-sustaining Treatment Act was recently proposed to legalize Aid in Dying. The global trend is that human "Right to Die" is discussed in the division of life and death, from the suspension of life-sustaining treatment to assisted death, and again in the order of euthanasia. In this paper, we started discussing dignified death and institutionalized patients' right to self-determination, looked at the controversy in the United States, which legislated assisted death in many states since the 2000s, and analyzed the main contents of California's End of Life Option Act and the data after enforcement. The strict requirements for Aid in Dying, such as voluntary confirmation of patients' intentions and doctors' obligation to provide information, and the results of California's Aid in dying system, composed of relatively diverse races, were reviewed.

• Journal of Korean Academy of Nursing
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• v.36 no.6
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• pp.1055-1064
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• 2006

Purpose: The purpose of this study was to analyze and clarify the ambiguous concept of DNR, and to distinguish between DNR and euthanasia. Method: This study used the process of Walker & Avant's concept analysis. Result: The definable attributes of DNR were care for comfort, no further treatment and no CPR. The antecedents of DNR were the autonomy of patients and families feelings about death, the uselessness of treatment and the right to die with dignity. The process of the DNR decision should be documented and the antecedents of DNR also can be a basis for objective standards of DNR decision-making. The result of DNR was the acceptance of death by patients and families. Conclusion: DNR is decided and documented by the antecedents of DNR, and the result is a natural acceptance of death, the last process of human life. Hospice care should be activated and nurses must be patient's advocates and families' supporters in the process.

• Transactions of Materials Processing
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• v.26 no.2
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• pp.95-100
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• 2017

In this study, the method of process design for side forming of a tooth part used for a component of automobile transmission was suggested using FE-simulations. To develop the side forming for the tooth part, in this paper, the shape factors of B.T.Pin was considered as design parameters. The shape factors of B.T.Pin were selected to be the round of pin, reinforced angle and reinforced length. Based on FE simulation results, appropriate shape factor without causing any defects was selected. In addition, to increase the strength of pin, the combination of shape factor having minimum stress after side forming was selected using FE-simulation. In addition, with design of a die set, cold side forming of the tooth part was experimented to estimate effectiveness of the designed B.T.Pin. From experiments, it was found that the tooth part with complete formation of the tooth was obtained without making any forming defects and punch fracture.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.1373-1378
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• 2007

Metal forming ins the process changing shapes and mechanical properties of the workpiece without initial material reduction through plastic deformation. Above all, because of hot working carried out above recrystallization temperature can be generated large deformation with one blow, it can produce with forging complicated parts or heat resisting super alloy such as Inconel 718 has the worst forgeability. In this paper, we established optimal variation of hot heading precess of the Inconel 718 used in heat resisting component and evaluated mechanical properties hot worked produce. Die material is SKD61 and initial temperature is $300^{\circ}C$. Initial billet temperature and punch velocity changed, relatively. Friction coefficient is 0.3 as lubricated condition of hot working. CAE is carried out suing DEFORM software before making the tryout part, and it is manufactured 150 ton screw press with optimal condition. It is known that forming load was decreased according to decreasing punch velocity.

• 한국신재생에너지학회:학술대회논문집
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• 2007.06a
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• pp.89-92
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• 2007

The metallic bipolar plate in PEMFC is widely used for automotive driving because of its advantages, i) high strength, ii) high chemical stability, iii) low gas permeability and iv) applicability to mass production. Especially, the metallic bipolar plate which is manufactured with the sheet metal stamping process can be applied in automotive PEMFC with less volume and weight because of its thin thickness but the formability and springback problems arise in real manufacturing process. The assessment for formability and springback of metallic bipolar plate should be performed before making stamping die sets. In this work, the methodology for determining the allowable draft angle of flow passage is introduced by using finite element analysis. In analysis results, as the draft angle of flow passage increase, the major strain and thinning is increase with exponential function. The allowable draft angle without fracture is presented by fitting the results. Additionally, the staking results with manufactured metallic bipolar plates by stamping process is presented.

• Transactions of Materials Processing
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• v.27 no.5
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• pp.276-280
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• 2018

This paper has developed a forging process for conical shells for making aluminum cylindrical large shells. An incremental forging process was applied to reduce forging loads and die cost. The preform is designed based on the crosssectional area of the final forged shape. Inner diameter of the preform for mandrel forging is constant, and outer diameter is conical so that it matches the cross-sectional area of the product. However, simulation confirmed that the larger diameter is smaller than predicted and the length is larger than predicted because in the initial stage of forging, the large diameter portion first comes into contact with the anvil at the initial stage of forging and stretches in longitudinal direction. So, it has developed a rule to design the preform considering 3-D deformation instead of plane strain deformation at the beginning stage of mandrel forging. The developed mandrel forging process can be applied to more similar products and economic benefits may be obtained.

• Journal of Korea Foundry Society
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• v.31 no.6
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• pp.336-341
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• 2011

Recently, aluminium usage in the automobile industry has been increased cause of its lightweight. The aluminium has a melting-solidification process in producing line and another melting process was needed in manufacturing process. Two times of melting process for making ingot and casting not only makes the loss of time and money but contaminates the air with Sox, Nox. For this reason, the holding furnace with laminated adiabatic material was developed. This holding furnace can deliver the molten aluminium directly to the industry needing molten aluminium. Recent holding furnace has above $15^{\circ}C/h$ of cooling rate and that causes solidification of molten aluminium. The ANSYS software was used to analysis the heat transfer. The adiabatic materials were laminated with optimized arrangement and holding furnace shape was changed with optimized modelling by ANSYS analysis for reducing the cooling rate of molten aluminium in holding furnace.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.8
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• pp.1371-1379
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• 2003

RP&M (Rapid Prototyping and Manufacturing) is the most appropriate technology for the small-lot production system, because the production cycle is getting shorter owing to various needs of the consumer. In this paper, rapid tooling technology is applied to the casting process. The casting process has the ability to reflect complicated shapes in one process. But it has not been widely used to make a die and mold because of the poor surface quality caused by air bubbles on the surface of the casting product. In this study, the porous casting mold is fabricated from a mixture of plaster and water-soluble binder. The porous casting mold can improve the characteristics of casting products with the help of the vacuum sealed casting process. The vacuum sealed casting process is an advanced technology that removes the air bubbles between the porous casting mould and the liquid metal, thus making the surface of the casting product finer. The purpose of this paper is to develop a high quality shoe mold using porous casting mold and to apply the RP&M technology to the shoe industry.