• 대한한방체열의학회지
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• 제3권1호
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• pp.36-42
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• 2004

Cold hypersensitivity is the condition with unusual cold sensitivity at temperature when others don't feel so. It is not disease in itself, but is known as having relationship with infertility, dysmenorrhea, anemia and endocrine disorder. The symptoms of cold hypersensitivity appear on limbs and abdomen especially, and may affect bowel movement such as constipation or diarrhea. We made a research of 86 healthy young girls who took medical examination and examined subjective bowel habit. The patients were divided into three group by defecation type, constipation(42), diarrhea(14) and normal group(30). Temperature differences$({\Delta}Ts)$ measured by DITI on upper and lower abdomen of each group had not statistically significance. Otherwise ${\Delta}Ts$ between upper arm and palm and between upper leg and foot were statistically signigicant. The severity of cold hypersensitivity on hands was in order constipation, normal and diarrhea group, and same as feet. The diarrhea patients had more severe cold hypersensitivity as compared with constipation patients. Correlation between ${\Delta}Ts$ on abdomen and hands or feet didn't exist. ${\Delta}Ts$ on hands and feet, however, had positive relationship. This research showed cold hypersensitivity could be related with diarrhea.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제2권2호
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• pp.240-244
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• 1999

저자들은 만성설사와 범발성 혈관내 응고 증후군을 동반한 2개월된 남아에서 장병성 선단 피부염을 의심하여 아연을 경구 투여한 후, 증상호전을 보인 장병성 선단 피부염 환아 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 한국미생물·생명공학회지
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• 제47권2호
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• pp.317-322
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• 2019

Gastroenteritis with diarrhea is one of the most infectious diseases in the world following respiratory infections. Notably, diarrhea-causing viruses (DVs) cause more than 70% of such cases. In this study, 3,065 stool specimens from patients with diarrhea (median age, 1.1 years; range, 0.0-91.1 years), who were admitted to the DanKook University Hospital, were examined using multiplex reverse transcription PCR (mRT-PCR). The target viruses were astrovirus (AstV), enteric adenovirus (EAdV), group A rotavirus (RotV), norovirus GI (NoV-GI), and norovirus GII (NoV-GII). The mRT-PCR results were analyzed based on various factors such as seasonality, age, presence of co-infection, and analyzed trends. The detection rate of the DVs during the study period was found to be 30.8% (n = 943/3,065). When the detection rate was analyzed monthly, the DV detection rate was found to be highest between December to January. Of the detected DVs, NoV-GII was the most common, accounting for 45.5% of the detected viruses (n = 446/980). Notably, 86.5% (n = 848/980) of the pathogens were detected in individuals who were less than 5 years of age. During the study period, NoV-GII and RotV showed alternating trends. In addition, both the number and rate of co-infections increased.

• 대한한방내과학회지
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• 제40권3호
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• pp.541-550
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• 2019

Objective: The aim of this clinical study was to describe the case of a patient who experienced chronic diarrhea related to seasonal changes that improved with herbal medicine treatment. Methods: A patient with diarrhea and globus hystericus was treated following treatment with Hoehyangbanchong-san-hap-Ukgan-san and Gamisachil-tang. A defecation and urination diary, the Bristol Stool Form Scale, and the Visual Analog Scale (VAS) were used to evaluate the effectiveness of this treatment. Results: During treatment, the patient's Bristol Stool Form Scale score changed from Type 7 to Type 4, and the VAS score was significantly decreased. The symptoms of diarrhea and globus hystericus almost subsided. Conclusion: In this case, Korean traditional herbal medicine reduced the clinical symptoms of diarrhea and globus hystericus.

• 대한수의학회지
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• 제21권2호
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• pp.81-86
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• 1981

Reproductive performance of gilts and sows in ordinary piggeries was investigated with special reference to litter size, piglets weaned per litter, the cause of preweaning mortality and the incidence of diarrhea. Biochemical properties of Escherichia coli isolated from piglets with diarrhea were also determined. The results obtained are summarised as follows: 1. Of the 2,226 gilts and sows farrowed, average number of piglets born alived and weaned piglets per litter were 8.9 and 7.1, respectively, indicating that both gilts and sows lost more than 20% of all their piglets prior to weaning. 2. The causes of preweaning mortality in order of prevalence were diarrhea (39.3%), pneumonia (20.0%), crushing (13.8%), starvation (11.0%) and born weak (10.3%). 3. Incidence of 3 diarrheal syndromes of piglets, i.e. 1 week diarrhea, 3 week diarrhea and post-weaning diarrhea were 18.4%, 66.1% and 15.5%, respectively, showing that most farms were suffering from so called 'white scours' in piglets 14~28 days old. 4. Biochemical properties of 268 cultures of E. coli isolated from diarrheal piglets were tested and compared with those of standard strains of porcine origin. All those properties of isolates were matched to standard E. coli teated while variable results were obtained with haemolytic capabilities of cultures tested. 5. Of 147 isolates 16 cultures (10.9%) were identified as colicin producers.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제4권2호
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• pp.243-248
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• 2001

저자들은 생후 2개월부터 지속되는 만성 설사를 주소로 내원한 환아에서 면역글로불린 정량 검사상 IgA의 결핍과 함께 $IgG_2$ 및 $IgG_4$ 결핍이 동반되어 있고 영아기에 빈번한 설사와 감염을 동반한 증례를 경험하였기에 보고하는 바이다.

• Asian-Australasian Journal of Animal Sciences
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• 제24권5호
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• pp.643-649
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• 2011

The objective of this study was to determine the effect of feeding direct-fed microbials (DFM) on the growth performance and prophylaxis of calf diarrhea during the pre-weaning period as an alternative to antibiotics. A multi-species DFM was formulated including three lactic acid bacteria (Lactobacillus salivarius Ls29, Pediococcus acidilactia Pa175, and L. plantarum Lp177), three Bacillus strains (B. subtilis T4, B. polymyxa T1 and SM2), one yeast, Saccharomyces boulardii, and a nonpathogenic E. coli Nissle 1917. Lactic acid bacteria and Bacillus strains were selected based on the antibacterial activity against various animal pathogens, especially pathogenic E. coli using agar diffusion methods in vitro. Test and control groups were fed milk replacer and calf starter supplemented with DFM ($10^9$ cfu each of eight species/d/head, n = 29) or with antibiotics (0.1% neomycin sulfate in milk replacer and Colistin 0.08% and Oxyneo 110/110 0.1% in calf starter, n = 15), respectively. Overall fecal score and the incidence rate of diarrhea were reduced in the DFM group compared to the antibiotics one. About 40% of calves in antibiotic group suffered from diarrhea while in DFM group only 14% showed diarrhea. There was no difference in the average daily gain and feed efficiency of two groups. The hematological levels of calves were all within the normal range with no significant difference. In conclusion, the feeding of multispecies DFM during the pre-weaning period could reduce calf diarrhea and there was no difference in the growth performance between the groups, thus showing the potential as an alternative to antibiotics.

• Parasites, Hosts and Diseases
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• 제52권5호
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• pp.479-485
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• 2014

Cryptosporidium diarrhea represents a relevant clinical problem in developing countries. In Al-Taif, a city of Saudi Arabia that lies at an altitude of an around 2 km above the sea level, Cryptosporidium infection seems to be undiagnosed in nearly all clinical laboratories. Furthermore, nothing was published regarding Cryptosporidium-associated diarrhea in this area. The objectives of this research were to (1) determine the Cryptosporidium prevalence among patients with diarrhea and (2) to estimate the performances of 3 different diagnostic methods. Total 180 diarrheal fecal samples, 1 sample per patient, were collected between January and August 2013. Samples were screened for Cryptosporidium with modified Zeihl Neelsen (ZN) microscopy, $RIDA^{(R)}$ Quick lateral flow (LF) immunotest, and a previously published PCR. The Cryptosporidium prevalence rate was 9.4% (17/180), 10% (18/180), and 11.6% (21/180) by microscopy, LF, and PCR test, respectively. Infection was significantly (P=0.004) predominant among children <5 years (22%) followed by children 5-9 years (11.1%). Although infection was higher in males than in females (16.2% males and 8.5% females), the difference was not statistically significant (P=0.11). Compared to PCR, the sensitivity of microscopy and the LF test were 80.9%, 85.7%, respectively. To conclude, high Cryptosporidium-associated diarrhea was found in this area especially in children ${\leq}9$ years. The PCR test showed the best performance followed by the LF test and ZN staining microscopy. The primary health care providers in Al-Taif need to be aware of and do testing for this protozoon, particularly for children seen with diarrhea.

• 한국동물위생학회지
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• 제31권3호
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• pp.265-272
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• 2008

Among calves' diseases, digestive diseases most frequently occur in Korea, and especially viral diarrhea is one of the most important diseases. This study was conducted to get some basic information for the control of the viral diarrhea in calves. The samples were obtained from 319 calves with clinical diarrhea from 195 farms in Gyeongnam south area (Gosung, Tongyung, Hadong) from June 2005 to August 2006, Viral detection was examined by polymerase chain reaction (PCR), Etiological viruses were detected from 171(53,6%) of 319 calves, and bovine rotavirus (BRV) were 130 (40,8%) and bovine viral diarrhea virus (BVDV) 41 (12,9%), and no coronavirus was confirmed, Statistical difference was found in BRV detection between summer (32.6%) and winter (57.7%). However there was no seasonal difference in BVDV. In detection rate of the calves under 19days, BRV was highest (55.1%), but BVDV lowest (5.1%). No big difference was in rate among herd size. However, BRV was lowest (26.8%) in the group over 51 heads, but BVDV was highest (19.5%) in the same.

• 혜화의학회지
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• 제13권1호
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• pp.225-241
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• 2004

Objectives & Methods: We investigated 45 books to study etiology, pathology and acupuncture & Moxibustion treatment of diarrhea. Result and Conclusion 1. The pathogenic factors of diarrhea are external sensation(外邪感受), jungjishiljo(情志失調), weakness of the spleen and stomach(脾胃虛弱), improper diet(飮食不節), sinyanghueson(腎陽虧損), sueumyujang(水飮留腸), liver Gi invades the sp1een(肝氣乘脾), uhhyuljeche(瘀血阻滯). 2. The etiological cause of diarrhea are closely related to the malfunction of the spleen & stomach(脾胃) and the related jang and bu(臟腑)'s pathological alternation such as spleen & stomach(脾胃), large intestine(大腸), small intestine(小腸), liver(肝), sp1een(脾), and kidney(腎). 3. Acupuncture and moxibustion treatment application of diarrhea with the meridian system are in the following order from the most often mentioned meridian system to the least, urinary bladder meridian(膀胱經), spleen meridian(脾經), stomach meridian(胃經), conception channel meridian(任脈經), liver mehdian(肝經), governor channel meridian(督脈經), large intestine meridian(大腸經), lung meridian(肺經), triple-warmer meridian(三焦經), gall bladder meridian(膽經), Pericardium meridian(心包經). 4. Acupuncture and moxibustion treatment application of diarrhea with meridian point are in the following order from the most often mentioned meridian point to the least, Cheonchu(天樞) sixteen times, Sin-gwol(神厥) fifteen times, Joksamni(足三理), Gwanwon(關元) each twelve times, Daejangsu(大腸兪) eleven times, Taechung(太衝), Bisu(脾兪), Sojangsu(小腸兪) each ten times,Sinsu(腎兪) nine times, CC12(中脘) eight times, Samchosu(三焦兪), gokcheon(曲泉), Harweom(下廉) each seven times, Samgan(三間), Sameungyo(三陰交), Yisa(意舍), Jungnyo, Gyeungmun(京門) each six times, Gyeonggol(京骨), Jangmun(章門) each five times, Sangnyeom(上廉), Hapgok(合谷), Yangmun(梁門), Sanggu(商丘), Yanggang(陽綱), Hoeyang(會陽), Gihyeol(氣穴), Taegye(太谿), Gihae(氣海) each four times.