• 대한의생명과학회지
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• 제20권3호
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• pp.168-172
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• 2014

It has recently been shown that hypothermia treatment improves brain ischemia injury and is being increasingly considered by many clinicians. However, the precise roles of hypothermia for brain ischemia are not yet clear. In the present study we demonstrated firstly that hypothermia induced beta-catenin-interacting protein 1 (CTNNBIP1) gene expression and its expression was dramatically decreased under ischemic conditions. It was also demonstrated that hypothermia activated endoplasmic reticulum (ER) stress sensors especially both, the phosphorylation of $eIF2{\alpha}$, and ATF6 proteolytic cleavage. However, the factors of apoptosis and autophagy were not associated with hypothermia. These findings suggested that hypothermia controlled CTNNBIP1 gene expression under ischemia, which may provide a clue to the development of treatments and diagnostic methods for brain ischemia.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 하계종합학술대회 논문집(5)
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• pp.106-109
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• 2000

The diode characteristics for therapy radiation sensor have been studied by irradiating therapy radiation from the MM22 microtron accelerator. Signal processing has been performed in the pulse mode which can process the signal fast. We have designed integrator, peak detector and synchronization circuit to detect diode signal in the pulse mode for implementation of portal image. We also read the diode signal by A/D board and displayed the peak value with LabView program. Because the quality of portal image obtained by film in the case of therapy radiation is much worse than that of diagnostic film, Digital radiography system by rectifier diode detector was suggested for portal Image.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 추계학술대회 논문집 학회본부 C
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• pp.1081-1083
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• 1999

The capacitive coupling technique has been used as conventional method for PD detection on the power cable line. Recently, however PD measurement using by high frequency is known to have an excellent sensitivity comparison with low frequency on-site. In this paper, the high frequency characteristic of two type of metal foil sensor was studied and the technique was proved to be more effective diagnostic method than conventional method for qualification of EHV cable and accessories.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.428-431
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• 1997

This study is the basic research on esophageal balloon dialation with automatic detection of the pressure change in the balloon and analysis using personal computer. In conventional method, the esophageal stricture is cured by surgically. Recently, balloon dialation method has been proposed and is popularized. In balloon dialation, detecting esophageal rupture is very important. When using radiological investigation, the leak of contrast medium is very dangerous. In proposed method, the detection of esopageal rupture can be peformed by detecting and analyze the pressure change of dialation balloon. Experimental system is composed of balloon catheter, pressure pump, pressure sensor, A/D converter and PC.

• The Plant Pathology Journal
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• 제34권2호
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• pp.85-92
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• 2018

Enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR), widely used for the detection of plant viruses, are not easily performed, resulting in a demand for an innovative and more efficient diagnostic method. This paper summarizes the characteristics and research trends of biosensors focusing on the physicochemical properties of both interface elements and bioconjugates. In particular, the topological and photophysical properties of quantum dots (QDs) are discussed, along with QD-based biosensors and their practical applications. The QD-based Fluorescence Resonance Energy Transfer (FRET) genosensor, most widely used in the biomolecule detection fields, and QD-based nanosensor for Rev-RRE interaction assay are presented as examples. In recent years, QD-based biosensors have emerged as a new class of sensor and are expected to open opportunities in plant virus detection, but as yet there have been very few practical applications (Table 3). In this article, the details of those cases and their significance for the future of plant virus detection will be discussed.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2001년도 춘계학술대회 논문집 유기절연재료 전자세라믹 방전플라즈마 연구회
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• pp.79-83
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• 2001

This is an investigation on the propagation characteristics of AE signal in GIS. The selection of measuring position and resonant frequency of AE sensor is one of the most important factor to optimize a diagnostic system. And natural frequency and harmonic response characteristics are indispensable to optimize those factors. So, in this investigation, we make a 3D model of 362kV GIS and make a modal and harmonic analysis to survey the vibro-acoustic property. Through the result of the analysis, we can make a further understanding on the vibro-acoustic characteristics of GIS.

• Smart Structures and Systems
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• 제5권2호
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• pp.139-152
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• 2009

Globally, civil infrastructures are deteriorating at an alarming rate caused by overuse, overloading, aging, damage or failure due to natural or man-made hazards. With such a vast network of deteriorating infrastructure, there is a growing interest in continuous monitoring technologies. In order to provide a true distributed sensor and control system for civil structures, we are developing a Structural Nervous System that mimics key attributes of a human nervous system. This nervous system is made up of building blocks that are designed based on mechanoreceptors as a fundamentally new approach for the development of a structural health monitoring and diagnostic system that utilizes the recently developed piezo-fibers capable of sensing and actuation. In particular, our research has been focused on producing a sensory nervous system for civil structures by using piezo-fibers as sensory receptors, nerve fibers, neuronal pools, and spinocervical tract to the nodal and central processing units. This paper presents up to date results of our research, including the design and analysis of the structural nervous system.

• Journal of Magnetics
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• 제14권3호
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• pp.132-136
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• 2009

This study investigated the radial pulse waveform obtained by a medical pulsimeter sensor. A pulse-sensing part array consisting of multiple Hall devices was located over a skin-contacting part with a hard magnetic material. The periodic movement of the magnetic material of the skin-contacting part affected the magnetic field in the pulse-sensing part array and was detected by multiple Hall devices. The analysis of a radial pulse waveform that is measured noninvasively by detecting the changes of the magnetic field can be used to develop a new diagnostic algorithm of oriental medical apparatus.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 학술회의 논문집 정보 및 제어부문 B
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• pp.920-923
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• 2003

An wearable electrocardiogram (ECG) monitoring system is a widely used non-invasive diagnostic tool for ambulatory patient who may be at risk from latent life-threatening cardiac abnormalities. In this paper, we have a portable ECG monitoring system with conductive fiber which was characterized by the small-size and the low power consumption. The system consists of conductive fibers, one-chip microcontroller, ECG preprocessing circuit, and monitoring software to be able to record and analyze in PC. ECG preprocessing circuit is made of pre-amplifier with gain of 10, band-pass filter with bandwidth of 0.5-120Hz and 2.5V offset circuit for A/D conversion. ECG signals obtained by sensor are included with corrupted noises such as a baseline wandering, 60 Hz power noise and interference noise by body movement. For cancellation corrupted noises in signals obtained by conductive fiber, we used the wavelet decomposition of wavelet transforms in MATLAB toolbox.

• 센서학회지
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• 제20권4호
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• pp.266-271
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• 2011

A reflection-type fiber-optic pH sensor, which is composed of a pH sol-gel film, plastic optical fibers, a mirror, a light source and a spectrometer, is developed in this study. As pH indicators, a bromthymol blue, a cresol red and a thymol blue are used, and they are immobilized in the sol-gel films. The emitted light from a light source is guided by a fiber-optic Y-coupler and plastic optical fibers to the pH sol-gel film in a pH sensing probe. The pH change in the sensing probe gives rise to a change in the color of the pH sol-gel film, and the optical characteristic of reflected light through the pH sol-gel film is also changed. Therefore, we have measured the spectra of reflected lights, which are changed according to the color variations of the pH sol-gel films with different pH values, by using of a spectrometer. Also, the relationships between the pH values and the intensities of reflected lights are obtained on the basis of the color variations of the pH sol-gel films.