• 대한물리치료과학회지
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• 제30권3호
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• pp.49-58
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• 2023

Background: This study aims to examine the useful- ness of the portable spirometer "The Spirokit" as a clinical diagnostic device through technology introduction, precision test, and correction. Design: Technical note Methods: "The Spirokit" was developed using a propeller-type flow rate and flow rate measurement method using infrared and light detection sensors. The level of agreement between the Pulmonary Waveform Generator and the measured values was checked to determine the precision of "The Spirokit", and the correction equation was included using the Pulmonary Waveform Generator software to correct the error range. The analysis was requested using the ATS 24/26 waveform recognized by the Ministry of Food and Drug Safety and the American Thoracic Society for the values of Forced Voluntary Capacity (FVC), Forced Expiratory Volume in 1second (FEV1), and Peak Expiratory Flow (PEF), which are used as major indicators for pulmonary function tests. All tests were repeated five times to derive an average value, and FVC and FEV1 presented accuracy and PEF presented accuracy as the result values. Results: FVC and FEV1 of 'The Spirokit' developed in this study showed accuracy within ± 3% of the error level in the ATS 24 waveform. The PEF value of 'The Spirokit' showed accuracy within the error level ± 12% of the ATS 26 waveform. Conclusion: Through the results of this study, the precision of 'The Spirokit' as a clinical diagnosis device was identified, and it was confirmed that it can be used as a portable pulmonary function test that can replace a spirometer.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5551-5556
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• 2012

Cytological examination is widely used as a diagnostic tool because of the ease of collecting cells from the involved area. However, the diagnostic yield of cytological examination is unsatisfactory; the reasons include sampling error, poorly prepared samples, small numbers of malignant cells, and low grades of cellular atypia. In this study, we focused on the high infectivity of adenovirus towards epithelial cells and applied the luciferase-expressing adenoviral vector to a new cancer cell detection tool. In addition, adenoviral infectivity was enhanced by modifying viral fiber proteins. The sensitivity of the diagnostic tool was tested using the NCI-H1299 lung cancer cell line, and validated in body fluid samples from cancer patients with a variety of etiology. Results showed that the adenovirus efficiently transfected NCI-H1299 with high sensitivity. Only 10 cancer cells were sufficient for detection of luciferase signals. In body fluid samples, the adenovirus confirmed the diagnosis for malignant and benign cancer, but not in non-epithelial cell derived samples. This study provides proof-of-concept for a more reliable and sensitive diagnostic tool for epithelium-derived cancer.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제11권1호
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• pp.91-99
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• 2000

목 적：주의력결핍 과잉운동 장애의 진단과 치료 효과를 평가하기 위해 전산화된 한국판 주의력 장애 진단 시스템(ADHD Diagnostic System：ADS)을 개발한 후, 연령별 규준을 산출하였다. 방 법：서울, 경기도, 강원도 지역의 유치원, 초등학교, 중학교에 재학중인 5세에서 15세 연령범위의 총 847명(남자 429명, 여자 418명)의 정상 아동 및 청소년이 규준집단으로 연구에 참여하였다. 또한 ADS의 신뢰도와 변별 타당도를 검증하기 위해 서울대학병원 소아정신과에서 DSM-IV 기준에 의해 ADHD로 진단받은 아동 30명이 본 연구에 포함되었다. 정상 집단의 아동들에게는 그들이 다니는 학교의 컴퓨터실에서 ADS를 실시하였고, ADHD 아동들에게는 소아정신과 외래 임상심리실에서 ADS를 실시한 후, 정상 아동의 자료에 입각해서 연령별 규준을 산출하였고, 신뢰도와 타당도 분석을 하였다. 결 과：ADS의 내적 일치도 계수(Cronbach's ${\alpha}$)는 .85이었다. 정상 집단과 ADHD 집단간에 오경보 오류를 제외한 모든 측정치에서 유의미한 차이가 있었다. 요인분석 결과, ADS 시각, 청각 검사에서 모두 3개의 요인이 산출되었다. 요인 1은 '주의력 요인'으로 누락오류, 오경보 오류, 민감도(d')가 포함되었고, 요인 2는 '정보처리 속도 요인'으로 정반응시간, 정반응시간의 표준편차가 여기에 해당되며, 요인 3은'충동성 요인'으로 반응기준(${\beta}$)이 포함되었다. 요인 1, 2, 3은 ADHD의 핵심적 증상과 정확하게 일치하므로, 이상과 같은 요인분석 결과는 ADS가 주의집중력 장애를 도구로써 구성 타당도가 있음을 입증해주었다. 판별분석 결과, 시각, 청각 ADS가 정상 아동과 ADHD 아동의 96.7%를 정확하게 변별해 주는 것으로 나타났다. 논 의：ADS가 주의력 결핍-과잉 운동 장애를 일관성이 있게 평가하는 신뢰롭고, 타당한 검사로 입증되었고, ADS를 통해 정상 집단과 ADHD 집단을 정확하게 분류할 수 있음이 시사되었다.

• 대한영상의학회지
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• 제84권6호
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• pp.1324-1336
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• 2023

목적 이첨 대동맥 판막의 아형과 판막 석회화의 정도에 따른 심장 CT와 경흉부심초음파의 이첨 대동맥 판막 진단 능력을 비교해 보고자 한다. 대상과 방법 대동맥 판막 치환술 전 심장 CT와 경흉부 심초음파를 시행한 266명의 환자(이첨 대동맥 판막, 106명; 삼첨 대동맥 판막, 166명)를 후향적으로 포함하였다. 심장 CT를 이용하여 판막의 모양을 평가하였고, 관상동맥 칼슘 측정 CT를 이용하여 판막의 칼슘 정도를 정량화하였다. 대동맥 판막은 융합형과 2-대동맥동형 아형으로 분류하였다. 심장 CT와 경흉부 심초음파의 진단정확도는 수술 소견을 대비표준으로 하여 계산하였다. 결과 CT는 이첨 대동맥 판막을 진단함에 있어서 경흉부 심초음파보다 민감도, 음성 예측도, 정확도에서 통계적으로 유의하게 높은 값을 보여주었다(각각 p < 0.001, p < 0.001, p = 0.003). 경흉부 심초음파는 판막의 석회화가 증가할수록 민감도가 감소하는 경향을 보였다. CT와 경흉부 심초음파 간의 진단 오류율은 2-대동맥동형 아형에서 10.9%, 융합형 아형에서 28.3%였다(p = 0.044). 결론 심장 CT는 이첨 대동맥 판막을 진단함에 있어 경흉부 심초음파보다 높은 진단능을 보여주며, 특히 판막 석회화가 심하거나 융합형의 아형인 환자에서 이첨 대동맥 판막을 진단하는데 도움을 줄 수 있다.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제54권11호
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• pp.493-497
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• 2005

This paper dealt with the influence of harmonic voltages on arrester diagnostics and its compensation method by using a designed Pspice arrester model. A pure sinusoidal voltage and its 3$^{rd}$ harmonic voltage were applied to the model, and the leakage current components were analyzed. The simulation results have shown that the peak value of resistive leakage current depends not only on the phase of the 3$^{rd}$ harmonic voltage but also on the magnitude of it. In this paper, an approximated 5$^{th}$ order polynomial formula by the Least-Square-Technique was derived, and correction factors which compensate the error caused by the 3$^{rd}$ harmonic voltage were calculated.

• 대한의용생체공학회:의공학회지
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• 제9권2호
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• pp.185-194
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• 1988

The dual-energy technique win used to separate the bone-only and tissue-only images from the conventional chest images. The equivalent thickness of the basic materials are estimated from low and high energy images of a given complex materials using the attenuation coefficient of ma serial componens. We showed that the image quality of dual-energy imaging method can be influenced by the ponlinearity and noise components of system and spectrum distributions The quantitative analysis of Calcium component was performed by dual-energy technique and it is shown that the concentration of the Calcium could be accurately estimated within 5% error range.

• 대한안전경영과학회지
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• 제18권1호
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• pp.141-145
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• 2016

This study was to improve to utilization of non dosimetry measurements for X-ray radiography. Experiments was passed off varying the X-ray tube voltage and the thickness of the aluminum filter by actual dose. Calculated results was set to the first beam quality factors, calculated first correction coefficient by the Microsoft Excel program was set as the second beam quality factors. To make the non dosimetry measurements simply, the Excel program apply to the new beam quality factors, the error was compared to the previous studies, and the results verify the calculated value of smaller errors.

• 대한기관식도과학회지
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• 제16권1호
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• pp.59-63
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• 2010

Cystic hygroma is a rarc congenital malformation of the lymphatic system and seen rarely in adults. It represents an error in communication between the large draining lymphatic channels and the venous system, Conventional surgical excision remains the most popular method of treatment in many developing countries despite the dangers associated with treatment modality. We present a case of huge cervical cystic hygroma in a 26-year old female who was treated with OK-432 sclerotherapy.

• 대한인간공학회지
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• 제32권1호
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• pp.1-7
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• 2013

Objective: This study proposes the application of Ecological Interface Design(EID) method that is effective for situation awareness in digitalized environment. Background: While cognitive interface design method such as Information Rich Display(IRD) is simply focused on existing information for user, EID method helps users' resource to be solved to higher ion task such as diagnostic and problem solving. Method: Using EID method based on Work Domain Analysis (WDA), it was analyzed and designed for Steam Generator(SG) Water Level control process in a digitalized Main Control Room of Nuclear Power Plant. Proposed EID example is evaluated through interviews by expert & operator. Results: The result of expert & operator showed that EID display might give an aid for operator's decision. Conclusion: The results can reduce critical accidental damage that occurred due to cognitive load and so critical human error. Application: This study may be impact on situation awareness study for digitalized interface design.

• Journal of Mechanical Science and Technology
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• 제19권2호
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• pp.716-727
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• 2005

Comprehensive measurements for velocity and temperature fields have been conducted. A Micro PIV 2-color LIF system have been setup to measure the buoyancy driven fields in a 1-mm heated channel with low Grashof-Prandtl numbers [$86]. Fluorescence microscopy is combined with an MPIV system to obtain enough intensity images and clear pictures from nano-scale fluorescence particles. The spatial resolution of the Micro PIV system is $75{\mu}m\;by\;67{\mu}m$ and error due to Brownian motion is estimated $1.05\%$. Temperature measurements have achieved the $4.7\;{\mu}m$ spatial resolution with relatively large data uncertainties the present experiment. The measurement uncertainties have been decreased down to less than ${\pm}1.0^{\circ}C$ when measurement resolution is equivalent to $76\;{\mu}m$. Measured velocity and temperature fields will be compared with numerical results to examine the feasibility of development as a diagnostic technique.