• Title/Summary/Keyword: Diagnosis of City

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PAX1 Methylation Analysis by MS-HRM is Useful in Triage of High-grade Squamous Intraepithelial Lesions

  • Wang, Zhen-Ming
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.891-894
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    • 2014
  • This study is aimed to investigate the role of paired boxed gene 1 (PAX1) methylation analysis by methylation-sensitive high-resolution melting (MS-HRM) in the detection of high grade lesions in atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (ASC-H) and compared its performance with the Hybrid Capture 2 (HC2) human papillomavirus (HPV) test. In our study, 130 cases with a diagnosis of ASC-H from the cervical cytological screening by Thinprep cytologic test (TCT) technique were selected for triage. Their cervical scrapings were collected and evaluated by using PAX1 methylation analysis (MS-HRM) and high-risk HPV DNA test (HC2), followed by colposcopy and cervical biopsy. Chi-square test were used to test the differences of PAX1 methylation or HPV infection between groups. In the detection of CIN2+, the sensitivity, specificity, the PPV, NPV and the accuracy of PAX1 MS-HRM assay and high-risk HPV (HR-HPV) tests were respectively 80.6% vs 67.7%, 94.9% vs 54.5%, 83.3%, vs 31.8%, 94.0% vs 84.4%, and 91.5% vs 57.7%. The PAX1 MS-HRM assay proved superior to HR-HPV testing in the detection of high grade lesions (CIN2+) in ASC-H. This approach could screen out the majority of high grade lesion cases of ASC-H, and thus could reduce the referral rate to colposcopy.

The Study of Factors Affecting Functional Disability of the Low Back Pain Patients Using Oswestry Disability Index(ODI) Assessment Tool (Oswestry Disability Index(ODI) 평가 도구를 이용한 요통환자의 기능장애에 영향을 미치는 요인 연구)

  • Lee, Sang-Ho;Park, Ji-Whan
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.13 no.1
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    • pp.18-25
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    • 2007
  • Objective: The Purpose of this study is the factive and descriptive research to identify the factors affecting the functional disability of the chronic low back pain patients. We investigated the effect of ODI by the Questionnaire and questioned an 70 patients who were back pain unit at G university hospital in D city from March to May, 2007. The functional disorder in this study were based on the Oswestry Disability Index(ODI) lower back pain disability questionnaire by fairbank(1980), and these data were proceeded by using SPSS/WIN version 10.0. Result: 1. The functional disorder in accordance with age, gender, academic background, occupation, diagnosis, pain cause, pain experience, treatment duration had no significantly similar difference statistically(p>0.05). 2. The functional disorder in accordance with duration of painful generation had statistically significance(P<0.05). Conclusion: we could verify that duration of painful generation affect on the factors affecting the functional disability of the low back pain patients.

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The Relationship between Ophthalmic Refractive Errors and Factors of Nutrition and Health (건강 및 식이요인과 굴절이상 시력장애와의 관련성)

  • 김영옥;최혜정;이순영
    • Korean Journal of Community Nutrition
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    • v.5 no.4
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    • pp.608-614
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    • 2000
  • The purpose of this study was to evaluate the relative importance among various biological and environmental factors on refractive errors. Various factors such as diseases, health related behavior such as drinking, smoking and exercise, as well as dietary factors were considered as a possible determinant. Surveys of 492 residents over 20 years of age in Kuri city were conducted during 1998. The survey included a refractive error test adopting a autokerato-refractometer, dietary survey using a 24 hour recall method, disease survey including blood and other diagnosis tests, and a health behavior survey using questionnaires with variables of smoking, drinking, and exercise. A stepwise logistic regression analysis was adopted to analyse the relative importance among independent variables of health behaviors, disease, and dietary factors on ametropias. As a result, in the case of myopia, liver dysfunction appeared to be the most important factors followed by the health related behavior of smoking and exercise as the second most important factors. Nutrient factors such as carotene and protein appeared to be the third most important factors. Similar results had been shown in the case of the hyperopia. In summary, liver dysfunction and the health related behaviors of drinking and smoking appeared to be more influential factors on abnormal eye sight of myopia and hyperopia than dietary factors.

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Monitoring Chigger Mites for Orientia tsutsugamushi in Field Small Mammals in Hwaseong-si, Gyeonggi-do, Korea, 2019-2020

  • Bahk, Young Yil;Ahn, Seong Kyu;Lee, Jinyoung;Kwon, Hyung Wook;Hong, Sung Jong;Kim, Tong-Soo
    • Parasites, Hosts and Diseases
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    • v.59 no.3
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    • pp.319-324
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    • 2021
  • Incidence of tsutsugamushi disease (scrub typhus) caused by Orientia tsutsugamushi, is steadily increasing. It is a mite-borne disease transmitted by chigger mites. In this study, the chigger mites were collected from field small mammals in Hwaseong-si (city), Gyeonggi-do (province), Korea, 2019 and 2020. The field small mammals captured were 56 Apodemus agrarius (94.9%) and 3 Crocidura lasiura (5.1%). A total of 7,531 chigger mites were collected from the captured small mammals. Using PCR test, 153 chigger mite pools were examined and 17 pools were reported positive for O. tsutsugamushi. The O. tsutsugamushi were identified to 5 strains; Jecheon strain was most prevalent, followed by Boryong strain. The other strains were OI011, Taguchi, and Shimokoshi. Collectively, these results provide essential regional information on mite-borne tsutsugamushi disease in the Hwaseong-si, and further contribute to bring awareness and rapid diagnosis for the tsutsugamushi disease.

A Study on the Remaining Concentration of Pesticides in Tap Water of Taejon City by Ellman′s Enzyme Method and the Countermeasure (Ellman 효소법에 의한 대전시 상수도내 살충제의 잔류농도 결정 및 그 대책에 관한 연구)

  • 이봉호;이영순;전종한
    • Journal of Environmental Science International
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    • v.8 no.1
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    • pp.19-26
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    • 1999
  • The degree of pesticides accumulation in tap water in Taejon from June 1995 to Apr 1996 was measured by Ellman's coupled enzyme assay. Since organic phosphate and carbamate pesticides specifically inhibit the neurotransmitter modulating enzyme acetylcholinesterase(AChE), the enzyme activity can be used as a diagnosis for the pesticides accumulation in water and various samples. During the period of this study, the enzyme activity was changed almost every week. The lowest enzyme activity was 64 % of that of the control reaction and there are several days showing about 100 % enzyme activity. In general, the enzyme activity is higher in summer than other seasons especially early spring times. The pH value of tap water was very close to neutral(pH 7.0) and it seems that the enzyme activity was not affected by the small pH changes. Either boiling of tap water or addition of NaOH solution decomposed the pesticide components. These results show that AChE assay is a convenient, sensitive, and reliable method for detection of pesticides in water samples.

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Analysis of the patient who were rejected by 119 emergency requests transferred (119 구급요청 거절 대상 환자의 이송 현황 분석)

  • Mun, Jun-Young;Choi, Jun-Won
    • The Korean Journal of Emergency Medical Services
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    • v.25 no.3
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    • pp.63-70
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    • 2021
  • Purpose: The study aimed to collect data from patients who were rejected by emergency requests for transfer to a tertiary hospital through 119 EMT and to analyze the data in the hospital to improve the plan. Methods: We analyzed 4,702 cases of emergency requests made by patients who were rejected by 119 emergency assistance out of the 22,568 patients who visited the emergency medical center in the C area of G metropolitan city from January 2018 through December 2020. The collected data were analyzed using IBM SPSS Statistics Version XX (IBM Corp., Armonk, N.Y., USA). Results: The major medical department with the largest number of such cases was the department of emergency medicine, with 2,519 cases (53.6%). Simple bruises were the most common diagnosis, with 2,819 cases (61.2%). KTAS classification was the highest with 3,562 patients (75.8%) in grade 4. As for the results, 4,084 patients (86.9%) were discharged from the hospital. Conclusion: Most of the patients who were rejected by emergency requests were non-emergency patients and were discharged from the hospital. emergency requests must be rejected at public relations and sites. In addition, the law should be amended to specifically present the reasons for refusal of emergency requests.

Heart Failure With Preserved Ejection Fraction and Frailty: From Young to Superaged Coexisting HFpEF and Frailty

  • Amina Rakisheva;Anzhela Soloveva;Anastasia Shchendrygina;Ilya Giverts
    • International Journal of Heart Failure
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    • v.6 no.3
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    • pp.93-106
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    • 2024
  • Being commonly diagnosed in elderly women and associated with comorbidities as well as ageing-related cardio-vascular changes, heart failure with preserved ejection fraction (HFpEF) has been recently considered as a distinct cardiogeriatric syndrome. Frailty is another frequent geriatric syndrome. HFpEF and frailty share common underlying mechanisms, often co-exist, and represent each other's risk factors. A threshold of 65 years old is usually used to screen patients for both frailty and HFpEF in research and clinical settings. However, both HFpEF and frailty are very heterogenous conditions that may develop at younger ages. In this review we aim to provide a broader overview on the coexistence of HFpEF and frailty throughout the lifetime. We hypothesize that HFpEF and frailty patients' profiles (young, elderly, superaged) represent a continuum of the common ageing process modified by cumulative exposure to risk factors resulting to a presentation of HFpEF and frailty at different ages. We believe, that suggested approach might stimulate assessment of frailty in HFpEF assessment and vice versa regardless of age and early implementation of targeted interventions. Future studies of pathophysiology, clinical features, and outcomes of frailty in HFpEF by age are needed.

Diagnosis and Control System of Wastewater Treatment Processes Using Intelligent Approaches (지능형 기법을 이용한 축산폐수처리장의 진단ㆍ제어 시스템)

  • Bae, Hyeon;Seo, Hyun-Yong;Jun, Byong-Hee;Kim, Sung-Shin;Kim, Ye-Jin
    • Proceedings of the IEEK Conference
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    • 2003.07d
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    • pp.1315-1318
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    • 2003
  • Wastewater treatment processes are usually located in the outskirts of cities. But these processes should be dealt with continuous maintenance by expert operators. Therefore, in this paper, unmaned and automated control system is designed for the SBR(Sequencing Batch Reactor) plant. This plant is constructed in Gimhae city. Networks and wireless modules are employed for the data transmission. A local controller is in the SBR plant as a client and a monitoring system is located in the other place as a server. Remote control and monitoring system are constructed at the laboratory of ours. Measured data from plant sensors are translated to the remote site using communication modules, and then the data could be displayed and analyzed by means of remote monitoring and control systems.

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Evaluation of a Community-Based Rehabilitation Program in Wonju City (원주시 지역사회중심 재활사업 평가)

  • Yi, Chung-Hwi;Lee, Hyun-Ju
    • Physical Therapy Korea
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    • v.10 no.1
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    • pp.139-158
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    • 2003
  • This study evaluated the community-based rehabilitation services provided by the Wonju Public Health Center from Jan. 2000 to Dec. 2002. Ninety-four persons with disabilities dwelling in the community participated and the surveys were completed in an interview during home visits. The respondents' demographic, socio-economic, and medical characteristics, rehabilitation service received, willingness to receive home-visit rehabilitation services, and satisfaction with the rehabilitation services were analyzed by frequency and percentage. A Likert scoring system consisting of five agreement-disagreement categories was applied to each item, consisting of Very Satisfied, Satisfied, So-So, Poorly Satisfied, and Very Poorly Satisfied. The major findings were as follows: 1) The rehabilitation services used included medical rehabilitation (26.9%), followed by social assistance (23.5%), diagnosis by a physician at home (17.3%), medical examination (12.3%), housekeeping services (6.2%), and vocational and educational rehabilitation (3.5%). 2) Of the medical services, the respondents desired physical therapy at home and free rental of rehabilitation equipment, such as wheelchairs, canes, walkers, the most, followed by home visit occupational therapy, nursing services, and oriental medicine service in descending order. 3) Some of the respondents expressed so-so satisfaction (50.0%) or dissatisfaction (16.9%) with the rehabilitation services provided by the Wonju Public Health Center. These findings should prove useful when planning or extending community-based rehabilitation programs for the homebound disabled in the community.

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The Validation of the Estimate Adolescents' Parents Attachment level by the Bird's Nest Drawings (새둥지화를 통한 청소년의 부모애착수준 타당화 연구)

  • Kim, Gab-Sook;Jeon, Young-Sook
    • Korean Journal of Human Ecology
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    • v.17 no.6
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    • pp.1065-1077
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    • 2008
  • The purpose of this study was to verify whether BND test was an appropriate tool for diagnosis of attachment security and to investigate difference of responsive Characteristics to the Bird's Nest Drawings according to parents attachment degree. The subjects in the study were 525 students, selected from senior high schools in D-city. The instruments used were parents attachment scale and Bird's Nest Drawings, and Discriminant analyses and crosstab analyses were used. The results were as follows. First, attachment indicators in the Bird's Nest Drawings discriminated according to group of parents attachment. Second, for male student, there was a significant difference placement nest, eggs, entire birds family, quality of line and tree picture according to attachment to father. For female student, there was a significant difference eggs, entire birds family, quality of line and tree picture according to attachment to father. For male student, there was a significant difference nest contents, placement nest, eggs, entire birds family, quality of line and tree picture according to attachment to mother. For female student, placement nest, space, nest size, eggs, entire birds family and quality of line according to attachment to mother.