• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.491-495
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• 2016

Background: Small B-cell non-Hodgkins lymphoma (NHL) is difficult to be distinguished from non-neoplastic reactive processes using conventional haematoxylin-eosin (HE) staining due to different interpretations among pathologists with diagnosis based on morphologic features. Ancillary examinations such as immunohistochemical (IHC) staining are essential. However, negative or doubtful results are still sometimes obtained due to unsatisfactory tissue processing or IHC technique. The polymerase chain reaction (PCR) as a molecular diagnostic technique is very sensitive and specific. Clonality detection of heavy chain immunoglobulin (IgH) gene rearrangement has been widely used to establish diagnosis of B-cell NHL. Aims: To elaborate interobserver variation in small B-cell NHL diagnosis based on morphologic features only and to confirm sensitivity and specificity of the PCR technique as an ancillary method. Materials and Methods: A toptal of 28 samples of small B cell NHL and suspicious lymphoma were interpreted by 3 pathologists in Sardjito General Hospital based on their morphology only. The reliability of assessment and the coefficient of interobserver agreement were calculated by Fleiss kappa statistics. Interpretation results were confirmed with IHC staining (CD20, CD3, Bcl2). PCR was performed to analyze the clonality of IgH gene rearrangement. Results: Interobserver agreement in morphologic evalution of small B cell NHL and chronic lymphadenitis revealed kappa coefficient 0.69 included in the substantial agreement category. The cases were divided into 3 groups based on morphology and IHC results; lymphoma, reactive process and undetermined group. PCR analysis showed 90% sensitivity and 60% specificity. Conclusions: The present study revealed a substantial agreement among pathologists in small B-cell NHL diagnosis. For difficult cases, PCR is useful as complementary method to morphologic and IHC examinations to establish definitive diagnosis.

• 치과방사선
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• 제26권2호
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• pp.147-152
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• 1996

Six observers with different amount of experience in the field of Oral and Maxillofacial Radiology interpreted the radiographs of 13 cases of ameloblastoma and 8 cases of odontogenic keratocyct which were confirmed histopathologically and showed pseudo-multilocular appearance and scalloped border radiographically. The authors examined the accuracy of radiologic diagnoses, interobserver agrement and intraobserver agreement. The obtained results were as follows; 1. The accuracy of radiologic diagnosis ranged from 0.48 to 0.81. The average value was 0.61. 2. The accuracy of radiologic diagnosis for ameloblastoma(0.55) was lower than that for odontogenic keratocyst(0.70) (P<0.05). 3. The overall agreement among the 6 observers was 14.3％ at the first interpretation and 19.0％ at the second interpretation. 4. The intraobserver agreement of each observer expressed in kappa index ranged from -0.14 to 0.64. The overall intraobserver agreement was 0.29. 5. The intraobserver agreement of each observer for ameloblastoma and odontogenic keratocyst ranged from -0.07 to 0.65 and from -0.25 to 1.00, respectively. The overall intraobserver agreement for ameloblatoma and odontogenic keratocyst were 0.27 and 0.26, respectively. 6. The diagnostic accuracy highly correlated to the intraobserver agreement(r=0.6370).

• Journal of Acupuncture Research
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• 제23권1호
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• pp.71-93
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• 2006

Objectives : This study is performed for proposing reasonable clinical study protocol at International standard clinical study of osteoarthritis of Knee Joint. Methods : We gave the eighteen oriental medicine doctors the questionnaire and the video about female patient who diagnosed Knee joint of osteoarthritis above 60 years old and they tested same patients using differentiation of symptoms and signs. Then they retested it after We educated them with diagnosis education text. Conclusion : The improvement of diagnosis agreement can be possible by developing standardized the same patients using differentiation of symptoms and by reeducation about it.

• 동의생리병리학회지
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• 제20권3호
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• pp.740-747
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• 2006

This study was undertaken to clinically inspect the accuracy of DSOM-diagnosis System of Oriental Medicine, which were used for the object diagnosis of oriental medicine in the dept. of oriental OB&GY, oriental medical hospital of Dong-Eui University- about uterus myoma patients. We analyzed the prescription and consequence of diagnosis about 16 patients -who had uterus myoma, were treated more than one month, were improved in myoma size, dysmenorrhea, menorrhagia- in the oriental medical hospital of Dong-Eui University from January to December 2004. The calculation consequence of disease mechanism was as follows. The stagnation of Ki(氣滯), liver(肝), heart.(心) was 10 patients 71.4%, some deficiency(虛證), wet syndrome(濕), cold syndrome(寒) was 9 patients 64.3%, blood stasis(血奈) was 8 patients 57.1%. The agreement of consequence about DSOM and diagnosis was 13 patients, 92.9%.

• 한국병원경영학회지
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• 제11권3호
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• pp.56-72
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• 2006

This study aims to deal with hospital staff's recognition on the opening of the medical services market, their attitude to the opening - agreement and disagreement, and their intention to use a foreign hospital or to consult its doctors again. It was conducted for 450 employees of one university hospital located in Gyeonggi Province, Korea with systemized questionnaires. The main results of this study are as follows: First, Medical technicians showed the highest level recognition on the opening of the medical services market. Second, The percentage of agreement to the opening was the highest for medical technicians and lowest for doctors while that of agreement was the highest for doctors and lowest for nurses. For residents, among doctors, the percentage of disagreement was the lower than that of agreement. Third, the intention to use a foreign hospital and to consult its doctor again was the lowest for medical engineers and the highest for doctors. Fourth, The most urgent task for local hospitals to accomplish in response to the opening was the improvement of the diagnosis and treatment technologies for nurses, and the improvement of the service provided by the hospital staff for the others. For doctors, in particular, the improvement of the diagnosis and treatment technologies was just the fourth urgent task. In conclusion, the result varies to the type of occupation. Apparent difference was found for doctors, in particular, that seem to be directly affected by the opening of medical services market. Local hospitals and doctors, therefore, should make efforts together to improve the diagnosis and treatment technologies. All the hospital employees of every type of occupation, meanwhile, need to prepare for the opening with medical service of improved quality.

• Journal of Korean Neurosurgical Society
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• 제47권2호
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• pp.89-94
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• 2010

Objective : To evaluate the role of cranial sonography and computed tomography in the diagnosis of neonatal intracranial hemorrhage and hypoxic-ischemic injury in an Indian set-up. Methods : The study included 100 neonates who underwent cranial sonography and computed tomography (CT) in the first month of life for suspected intracranial ischemia and hemorrhage. Two observers rated the images for possible intracranial lesions and a kappa statistic for interobserver agreement was calculated. Results : There was no significant difference in the kappa values of CT and ultrasonography (USG) for the diagnosis of germinal matrix hemorrhage/intraventricular hemorrhage (GMH/IVH) and periventricular leucomalacia (PVL) and both showed good interobserver agreement. USG, however detected more cases of GMH/IVH (24 cases) and PVL (19) cases than CT (22 cases and 16 cases of IVH and PVL, respectively). CT had significantly better interobserver agreement for the diagnosis of hypoxic ischemic injury (HII) in term infants and also detected more cases (33) as compared to USG (18). CT also detected 6 cases of extraaxial hemorrhages as compared to 1 detected by USG. Conclusion : USG is better modality for imaging preterm neonates with suspected IVH or PVL. However, USG is unreliable in the imaging of term newborns with suspected HII where CT or magnetic resonance image scan is a better modality.

• 대한한의진단학회지
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• 제21권1호
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• pp.13-25
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• 2017

Objectives The purpose of this study was to evaluate the reliability and the validity of Mibyeong Questionnaire (MQ). The subjects enrolled in this study was 165 from July 2015 to Jan. 2016. The surveys were conducted twice with 3 month terms. Methods The Cronbach's ${\alpha}$ analysis for internal reliability, Pearson Correlation Coefficient analysis for test-retest reliability, Factor analysis with varimax rotation for construct validity, Kappa analysis for diagnostic reliability were used. The significant p-value was less than 0.05. Results and Conclusions The result showed that the Cronbach's ${\alpha}$ of MQ was .857-.937 and total was .913. The reliabilities between test and retest for the MQ were .666-.832 (0.416-0.673, in case of including recovery question) in intraclass correlation coefficient (ICC). The Kappa of recovery question in each item was ranged 0.23(80.6% in agreement rate) to .46(87.9% in agreement rate). In test-retest the Kappa value of Mibyeong diagnosis referred by median value was .418(71% in agreement rate). This study revealed that MQ is a reliable and valid questionnaire.

• Clinics in Shoulder and Elbow
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• 제24권2호
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• pp.98-105
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• 2021

Background: Our aim is to determine the interobserver reliability for surgeons to detect Hill-Sachs lesions on magnetic resonance imaging (MRI), the certainty of judgement, and the effects of surgeon characteristics on agreement. Methods: Twenty-nine patients with Hill-Sachs lesions or other lesions with a similar appearance on MRIs were presented to 20 surgeons without any patient characteristics. The surgeons answered questions on the presence of Hill-Sachs lesions and the certainty of diagnosis. Interobserver agreement was assessed using the Fleiss' kappa (κ) and percentage of agreement. Agreement between surgeons was compared using a technique similar to the pairwise t-test for means, based on large-sample linear approximation of Fleiss' kappa, with Bonferroni correction. Results: The agreement between surgeons in detecting Hill-Sachs lesions on MRI was fair (69% agreement; κ, 0.304; p<0.001). In 84% of the cases, surgeons were certain or highly certain about the presence of a Hill-Sachs lesion. Conclusions: Although surgeons reported high levels of certainty for their ability to detect Hill-Sachs lesions, there was only a fair amount of agreement between surgeons in detecting Hill-Sachs lesions on MRI. This indicates that clear criteria for defining Hill-Sachs lesions are lacking, which hampers accurate diagnosis and can compromise treatment.

• Journal of Acupuncture Research
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• 제30권4호
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• pp.161-167
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• 2013

Objectives : This study was done for comparing the result of Sasang constitution diagnosis using portable Ryodoraku and that of self-report questionare for Sasang constitution classification II QSCC II. Methods : We investigated 41 cases to collect the data. we analyzed the result of portable Ryodoraku and self-report(QSCC II). Results : 1. The degree of agreement between those results from portable Ryodoraku and QSCC II was statistically significant. 2. The dgree of agreement between those results from portable Ryodoraku and QSCC II was statistically significant in male and female. Conclusions : It is suggested that portable Ryodoraku should be available for diagnosing Sasang constitution.

• KIEE International Transactions on Electrophysics and Applications
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• 제3C권4호
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• pp.130-135
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• 2003

This study describes neural network based dissolved gas analysis using composition patterns of gas concentrations for transformer fault diagnosis. DGA samples were gathered from related literatures and classified into six types of faults and then a neural network was trained using the DGA samples. Diagnosis tests were performed by the trained neural network with DGA samples of serviced transformers, fault causes of which were identified by actual inspection. Diagnosis results by the neural network were in good agreement with actual faults.