• Proceedings of the Korean Operations and Management Science Society Conference
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• 1989.10a
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• pp.108-125
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• 1989

A new product development is critical to the growth and success of most business firms. Increasingly, the new product development is recognized as an essential component of the corporate plan. But, relatively few research investigations have focused on the elements of a new product development strategy and its performance results. This study aims to identify the patterns of new product development strategy which business firms adopt, and its performance results. To identify these patterns and results, 268 firms in four industries known to be active in new product development were selected as a matter of convenience, and surveyed by the questionnaire and interviews. The questionnaire is composed of 67 strategy variables, 8 performance variables, and other variables. To analyze the data from samples, various statistical methods such as factor analysis, Pearson correlation analysis, sluster analysis, and one-way ANOVA were employed. This analysis brought forth the following major findings: First, three new product development strategy patterns were identified. Each strategy pattern was proved to be different from the others in terms of group of strategy elements that were adopted. Second, the new product development strategy was closely linked to its performance. Third, the difference of performance results among strategy groups in each industries was rather significant, however, the performance difference among industries in each strategy group was less significant.

• Journal of the Korea Society of Computer and Information
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• v.14 no.4
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• pp.131-139
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• 2009

The decision makers of IT projects are faced to situations to choose a best development method between inhouse development and solution purchase when companies must develop a new system or enhance the existed system. For those decision makers related to the IT projects, this study provides them with meaningful results through the ISBSG project repositary, how each development method, such as a development inhouse, a solution purchased, a combined method, impact the function point, which is a critical factor to measure the required time, efforts, cost of IT project development.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.6
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• pp.117-125
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• 2020

This paper aims to investigate FDI attractive factors, which are important to formulate policies to attract Korean direct investment into Vietnam. Based on the literature review and the results of interview with 27 Korean investors in Vietnam, we determined the model of variables attracting Korea's FDI into Vietnam. It is used to assess the impact of attractive factors belonging to three groups of variables to support investment decision; they are macroeconomics variables (including market size factor, labor cost factor, and market openness factor), policies variables (including monetary policy factor and tax rate gap factor), and microeconomics variables (geographic advantage factor representative by location). This research also utilized a relatively new quantitative research method based on the Autoregressive Distributed Lag model (ARDL) with the time data chain from 1995 to 2017 of Korean FDI into Vietnam. It analyzes long-term relationships between dependent variables and independent variables. The result of this study indicates that there are three positive factors (low wages, trade openness and government policy) explaining the FDI flows in the long term. The result also shows that incentive tax policy has had a positive impact on Korean FDI, which has satisfied the aim of seeking efficiency of Korean investors.

• Journal of the Korean Society of Costume
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• v.64 no.4
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• pp.106-117
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• 2014

The purpose of this study is to provide basic information for the development of well-fitting and comfortable brassieres for women in their 30s, based on the classification of breast shapes by utilizing 3D body measurement data of women in the age group. The result of processing the measurements from the 3D body scan data through RapidForm 2006 shows that while the vertical body measurements decrease, the horizontal measurements, which indicates the degree of obesity, increase proportionally with age. Also, the relevant measurements for upper breasts increase proportionally with age, while the measurements for lower part of the breasts decrease as the degree of sagging increases. Four composition factors of the breasts were identified through the factor analysis: Factor 1 is the level of volume in the breasts and the surrounding area; Factor 2 is the position of nipples and the shape of upper part of breasts; Factor 3 is the position and vertical length of the breasts; Factor 4 is the shape of lower part of breasts; and Factor 5 is the shape of inner part of breasts and degree of width between both breasts. The breasts have been categorized into three distinctive shapes: Breast Shape 1, Breast Shape 2 and Breast Shape 3. According to the results of the cluster analysis, the largest percentage (36.68%) of women in their 30s falls into the category of Breast Shape 2 with small volume and flat upper breasts, followed by Breast Shape 1 (32.66%) with large volume in the upper and lower parts of breasts, and large side to side area, and Breast Shape 3 (30.65%) with average volume and width between breasts.

• Journal of the Korean Institute of Landscape Architecture
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• v.30 no.2
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• pp.39-49
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• 2002

The purpose of this study is to propose an objective and rational methodology for the selection of proposed sites far the National Trust(NT), which is the new alterative proposal far the conservation of natural environments destroyed by injudicious land development and economic growth. That is to enforce many analysis for the effective estimation of rare ecological and landscape resources and to propose a model based on estimation and united indicators. Using the estimative model, we apply it to the selection of the proposed site in micro scale and simultaneously offer the basic methodology of effective and systematic land conservation in macro scale. The results of this study are as follows: 1) The results of analysis for the reliability of estimative items and indicators, presented no problem in that the coefficient of reliability was over 0.7. 2) The correlation measure of the estimative indicator indicated that 'succession'and 'regenerating restorability' were highly correlative in the item of plants. Another three items showed a tendency to be alike. 3) The results of factor analysis on the characteristics of indicators, classified plants into four categories including a stable factor. The item of animals was classified as a stable and rare factor. The item of landscape was classified as a physical and mental factor and the environment as a pollutional and conditional factor. 4) The model of estimation created through factor analysis was valid for the approval of the regression model because significant probability was 0.00. When we consider the NT proposed site as a complex body that is composed of diverse natural and manmade resources, certainly the synthetic methodology of estimation is needed. If these studies are carried out, NT sites will be selected more rationally and effectively than at present. Consequently, they have the potential to play a core role of natural ecosystem conservation in Korea.

• Journal of the Korean Society of Costume
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• v.63 no.1
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• pp.97-107
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• 2013

To give satisfaction with the fit to a wearer, the wearer's body size and body types should be considered first, this study conducted the descriptive statistical analysis on the upper body measurements of women in their 20s because their body shape has reached the completion stage of adult female's physical development. Also, the analysis classified their upper body types into groups to secure basic data for (maximum satisfaction with the fit of ready-to-wear clothing. The factor analysis was conducted using 49 items of measurement. The main factor analysis was used as a factor extraction method. After extracting the factors with Eigenevalues over 1, the factor loadings were drawn using the Varimax rotation. As a result, 6 factors were extracted. To secure internal consistency, factors that could lower the reliability of the experiment were taken out, so only 36 of the 49 items were used for the analysis. After selecting the items to recognize the main features of each body type, they were used for the final factor analysis. The entire R square of the 6 factors was 84.06%. To classify the upper body types of women in their 20s and to recognize the main features of each body shape type, the researcher conducted the cluster analysis with the items generated from the factor analysis. Through the cluster analysis, the upper body type of women in their 20s were classified into 3 body types. Also, since there are some restrictions on this research objects in terms of local and numbers of measured objects, the results of the this research should only be used as basic data.

• Journal of Life Science
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• v.22 no.5
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• pp.569-574
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• 2012

This study was conducted to investigate the effect of exercise on oxidative stress, nerve growth, and hepatocyte growth factors in obese children. After 12 weeks of aerobic exercise training, the aforementioned parameters before and after the training were compared. As a result, the nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) were shown to be lower in the OT than in the NT before and after the training, respectively ($p$ <0.05). The NGF was shown to have increased in both groups after the training ($p$ <0.05). The hepatocyte growth factor (HGF) was shown to be higher in the OT than in the NT before the training ($p$ <0.05), with no difference found afterwards. The malondialdehyde (MDA), ox-LDL, and 8-OHdG (Oxo-2'-deoxyguanosine) were shown to be higher in the OT than in the NT ($p$ <0.05). For ox-LDL, a difference was found between before and after the training ($p$ <0.05). The results of this study showed that obesity induced oxidative stress and caused the abnormalities of nerve and HGF secretion in obese children, and that the 12 weeks of aerobic exercise increased NGF levels, thereby promoting the development of neurogenesis in children.

• Health Policy and Management
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• v.20 no.2
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• pp.40-52
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• 2010

Health insurance fees are set by relative value scales and conversion factors. Since 2008 the conversion factor has been classified into 7 according to the provider type, and a separate contract has been made respectively. As such classification of the conversion factor reflects only the different characteristics of providers, however, further classification to reflect the different cost structures of providers is proposed. Cost varies according to the type of not only providers but also services each provider supply. In fact different cost structures of providers are the result of their different services. This study analyzed the cost structure of medical services to propose a new approach to the classification of the conversion factor. This study analyzed the cost structure of medical services using cost data constructed in the revision study of relative value scales. The cost data consist of doctor's fee, support staff's fee, cost of medical equipments, cost of medical supplies and indirect cost. The proportion of each cost component to the total cost was analyzed in terms of service department and service type. 72 service groups are defined in terms of the combination of service department and service type. Through cluster analysis, 72 service groups were reduced into 7 clusters each of which has a similar cost structure. Conversion factor is contracted annually to reflect the change in the cost of providing medical services. So the classification of conversion factor has to be based on the cost structures of medical services, not the characteristics of providers. Service clusters derived in this study can be used as a new classification for health insurance fee contract.

• Archives of Plastic Surgery
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• v.40 no.6
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• pp.676-686
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• 2013

Background To overcome the potential drawbacks of a short half-life and dose-related adverse effects of using active transforming growth factor-beta 1 for cartilage engineering, a cell-mediated latent growth factor activation strategy was developed incorporating latent transforming growth factor-${\beta}$1 (LTGF) into an electrospun poly(L-lactide) scaffold. Methods The electrospun scaffold was surface modified with NH3 plasma and biofunctionalised with LTGF to produce both random and orientated biofunctionalised electrospun scaffolds. Scaffold surface chemical analysis and growth factor bioavailability assays were performed. In vitro biocompatibility and human nasal chondrocyte gene expression with these biofunctionalised electrospun scaffold templates were assessed. In vivo chondrogenic activity and chondrocyte gene expression were evaluated in athymic rats. Results Chemical analysis demonstrated that LTGF anchored to the scaffolds was available for enzymatic, chemical and cell activation. The biofunctionalised scaffolds were non-toxic. Gene expression suggested chondrocyte re-differentiation after 14 days in culture. By 6 weeks, the implanted biofunctionalised scaffolds had induced highly passaged chondrocytes to re-express Col2A1 and produce type II collagen. Conclusions We have demonstrated a proof of concept for cell-mediated activation of anchored growth factors using a novel biofunctionalised scaffold in cartilage engineering. This presents a platform for development of protein delivery systems and for tissue engineering.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.10
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• pp.1674-1682
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• 2020

Objective: This study aimed to elucidate the effect of miR-140 on the proliferation of porcine fetal fibroblasts (PFFs) and identify the target genes of miR-140 in PFFs. Methods: In this study, bioinformatics software was used to predict and verify target genes of miR-140. Quantitative polymerase chain reaction and western blot were used to detect the relationship between miR-140 and its target genes in PFFs. Dual luciferase reporter gene assays were performed to assess the interactions among miR-140, type 1 insulin-like growth factor receptor (IGF1R), and SRY-box 4 (SOX4). The effect of miR-140 on the proliferation of PFFs was measured by CCK-8 when PFFs were transfected with a miR-140 mimic or inhibitor. The transcription factor SOX4 binding to promoter of IGF1R was detected by chromatin immunoprecipitation assay (ChIP). Results: miR-140 directly targeted IGF1R and inhibited proliferation of PFFs. Meanwhile, miR-140 targeted transcription factor SOX4 that binds to promoter of porcine IGF1R to indirectly inhibit the expression of IGF1R. In addition, miR-140 inhibitor promoted PFFs proliferation, which is abrogated by SOX4 or IGF1R knockdown. Conclusion: miR-140 inhibited PFFs proliferation by directly targeting IGF1R and indirectly inhibiting IGF1R expression via SOX4, which play an important role in the development of porcine fetal.