• Title/Summary/Keyword: Development factor

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A Study on the Development of the Korean Family Resilience Scale (한국가족의 기능 회복력 측정도구 개발 연구 - 만성질환아 가족을 대상으로 -)

  • ;;;;Hesook Suzie, Kim
    • Journal of Korean Academy of Nursing
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    • v.32 no.4
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    • pp.560-569
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    • 2002
  • The purpose of this study was to develop an instrument to measure family resilience for Korean families with a chronically ill child, and to test the validity and reliability of the instrument. Method: The items of instruments used based on the researchers' previous study of concept analysis of Korean family resilience. Nineteen item scales were developed with five domains. In order to test reliability and validity of the scale, data were collected from 231 families, who had a child with a chronic illness. Data was collected between August and September of 2001 in a 3rd level University Hospital in Seoul, Korea. Result: The results were as follows: As a result of the item analysis, 19 items were selected from the total of 37 items, excluding items with low correlation with the total scale. Five factors were evolved by factor analysis, which explained 56.4% of the total variance. The first factor 'Family strength' explained 28.5%, 2nd factor 'Family maturity' 8.7%, 3rd factor 'The ability to use of external resources' 7.0%, 4th factor 'Control' 6.6%, 5th factor 'The driving force for finance' 5.7%. The attributes in these factors were different with those identified by concept analysis of the family resilience in Korean families from the previous study. Cronbach's $\alpha$ coefficient of this scale was .8039 and Guttman spilt- half coefficient was .8184. Conclusion: The study support the reliability and validity of the scale. Because the main concept of family resilience was family strength, there were distinct differences in dimensions of family functioning scales.

A Study on the Quantitative and Evaluation Weights of National Greenhouse Gas Emission Factors in the Mineral Industry (광물산업의 국가온실가스배출계수 정량·평가항목 가중치에 관한 연구)

  • Yoon, Yoongjoong;Cho, Changsang;Jeon, Eui Chan
    • Journal of Climate Change Research
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    • v.9 no.1
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    • pp.81-90
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    • 2018
  • "The Framework Act on Low-Carbon Green Growth" specifies the requirements for the development and verification of emission factors for establishing reliable national greenhouse gas statistics. The scope of the regulations covers the development and validation of energy, industrial processes, solvents and other product use, agriculture, land use, land use change and emission and absorption coefficients of the forestry and waste sector as defined in the 1996 IPCC Guideline and GPG 2000, The minerals sector to be covered in this study belongs to industrial processes. As a representative method for quantifying and evaluating GHG emission factors, there are emission grade quality grading and DARS (Data Rating Rating System) in the 'Procedures for Preparing Emission Factor Documents (1997)' reported by US-EPA. However, the above two methods are not specific and comprehensive, and lack the details for accurate emission factor verification. Therefore, there is a need for a method for verifying and quantifying certified greenhouse gas emission factors that reflects characteristics of each industry sector in Korea and accord with IPCC G/L and GHG target management. In this study, we conducted a weighted study on quantitative and evaluation lists of emission factor using questionnaires to develop a more accurate methodology for quantifying national greenhouse gas emission factors in the mineral sector. Quantification and evaluation of emission factor are classified into essential verification and quality evaluation. The essential verifications are : administrative compatibility, method of determining emission factors, emission characteristics, sampling methods and analysis methods, representativeness of data. The quality evaluations consisted of the quality control of the data, the accuracy of the measurement and analysis, the level of uncertainty, not directly affect the emission factor, but consisted of factors that determine data quality.

Comparison of Gene Expression Levels of Porcine Satellite Cells from Postnatal Muscle Tissue during Differentiation

  • Jeong, Jin Young;Kim, Jang Mi;Rajesh, Ramanna Valmiki;Suresh, Sekar;Jang, Gul Won;Lee, Kyung-Tai;Kim, Tae Hun;Park, Mina;Jeong, Hak Jae;Kim, Kyung Woon;Cho, Yong Min;Lee, Hyun-Jeong
    • Reproductive and Developmental Biology
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    • v.37 no.4
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    • pp.219-224
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    • 2013
  • Muscular satellite cell (SC), which is stem cell of postnatal pig, is an important for study of differentiation into adipogenesis, myogenesis, and osteoblastogenesis. In this study, we isolated and examined from pig muscle tissue to determine capacity in proliferate, differentiate, and expression of various genes. Porcine satellite cells (PSC) were isolated from semimembranosus (SM) muscles of 90~100 days old pigs according to standard conditions. The cell proliferation increased in multi-potent cell by Masson's, oil red O, and Alizarin red staining respectively. We performed the expression levels of differentiation related genes using real-time PCR. We found that the differentiation into adipocyte increased expression levels of both fatty acid binding protein 4 (FABP4) and peroxisome proliferator-activated receptor gamma ($PPAR{\gamma}$) genes (p<0.01). Myocyte increased the expression levels of the myosin heavy chain (MHC), myogenic factor 5 (Myf5), myogenic regulatory factor (MyoD), and Myogenic factor 4 (myogenin) (p<0.01). Osteoblast increased the expression levels of alkaline phosphatase (ALP) (p<0.01). Finally, porcine satellite cells were induced to differentiate towards adipogenic, myogenic, and osteoblastogenic lineages. Our results suggest that muscle satellite cell in porcine may influence cell fate. Understanding the progression of PSC may lead to improved strategies for augmenting meat quality.

Effects of Technology and Innovation Management and Total Factor Productivity on the Economic Growth of China

  • LEE, Jung Wan;XUAN, Ye
    • The Journal of Asian Finance, Economics and Business
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    • v.6 no.2
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    • pp.63-73
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    • 2019
  • The paper aims to investigate relationships between technology and innovation management, total factor productivity and economic growth in China. By comparing the trends in total factor productivity growth of industrialized economies (i.e. OECD), this study intends to showcase the importance of total factor productivity progress in the Chinese economy. The study employs time series data of an annual basis for the period from 1977 to 2016 retrieved from the World Development Indicator. The study employs unit root test, cointegration test, fully modified least squares estimation method, canonical cointegrating regression and dynamic least squares estimation method to test the hypotheses. The results of the cointegrating regression analysis show that manufacturing growth leads to an increase of total factor productivity in the short-run in China. The findings of the study suggest that manufacturing (i.e. technology and product innovation) is positively related to the increase of total factor productivity in the short-run and total output growth in the long-run. The findings suggest that promoting technology and innovation management and supporting R&D subsidies may reduce the marginal cost of conducting R&D and increase the rate of technology and innovation management and R&D activity and therefore, the total factor productivity growth rate.

Stress intensity factor and stress distribution near crack tip for infinite body containing regid inclusion with crack shape (균열형상의 강체함유물을 포함하는 무한체에 대한 균열선단 부근의 응력분포와 응력세기계수)

  • Lee, Kang-Young;Kim, Jong-Sung
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.22 no.3
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    • pp.680-683
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    • 1998
  • In case of the infinite body containing a rigid inclusion with line crack shape, stress intensity factor is determined and the relation between stress intensity factor and stress distribution near a crack tip is developed. Also, the relation between stress intensity factor and Kolosoff stress function is developed. Finally, these results are compared with those that the crack surface is under no traction.

Insulin-like Growth Factor-1 (IGF-1) Gene Expression Is Enhanced under Hypothermia but Depressed under Additional Ischemic Stimulus

  • Kwon, O-Yu;Kwon, Kisang;Yu, Kweon;Kim, Seung-Whan
    • Biomedical Science Letters
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    • v.21 no.2
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    • pp.126-130
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    • 2015
  • There are several studies that show hypothermia improves cellular ischemia damages on experimental and clinical bases. However, its exact molecular mechanisms are unclear. In this study, we demonstrate that hypothermia induced insulin-like growth factor 1 (IGF1) gene expression, and its expression was dramatically decreased under ischemic insults. It was also demonstrated that hypothermia activated endoplasmic reticulum (ER) stress sensors especially both the phosphorylation of $eIF2{\alpha}$ (eukaryotic translation initiation factor 2 alpha) and ATF6 (activating transcription factor-6) proteolytic cleavage. However, the factors of apoptosis and autophagy were not associated with hypothermia. We suggest that hypothermia-treated IGF1 gene expression after ischemia may show a good possibility for the development of treatments and diagnostic methods in cerebral ischemic damages.

Development for Determining Impact Factor with Respect to Traffic Loads of Highway Bridges (고속도로 교량국조물의 통행차량에 의한 충격계수 산정방법 개발)

  • 구봉근;신재인;류택은;이재범;류연종
    • Proceedings of the Korea Concrete Institute Conference
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    • 2001.11a
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    • pp.809-814
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    • 2001
  • In this paper, dynamic properties of a bridge by traffic loads, is proposed as a reasonable method for the determining the impact factor. In addition, impact factors obtained from previous inspection reports were classified by the span length of the bridge, kind of the bridge and type of the bridge and adjusted the result of the impact factor by the statistical method and presented problems. Also, the determining method of the impact fatter using traffic load is proposed and compared the proposed method with the specification code. The method estimating the impact factor by the traffic loads can be efficiently concluded to the response of structure as reflecting the impact factor and saving the investigation cost. Also it is expected to use to maintenance of structures using the usual test of the bridge.

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A Forecast Model on Vocational High School for Runaway Students Using Data Mining (데이터 마이닝을 적용한 실업계 고등학생의 가출 예측모형)

  • Lee, Ju-Rhee
    • Journal of Families and Better Life
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    • v.27 no.2
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    • pp.203-211
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    • 2009
  • This study was conducted to evaluate a forecast model designed to describe a vocational high school for runaway students. The study included 2000 adolescents from the KEEP(Korean Education and Employment Panel). A Data mining decision tree model revealed that: (1) Suicide ideation was a risk factor for running away among smokers. (2) High self-evaluation was a risk factor for running away among individuals that smoked and had no suicide ideation. (3) Drinking was predicted as a risk factor for no smokers, while family life dissatisfaction was predicted as a risk factor among non-smokers that drank. (4) Negative relationship with mother was predicted as a risk factor among non-drinking non-smoking.

Hemophilia (혈우병)

  • Yoo, Ki Young
    • Clinical and Experimental Pediatrics
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    • v.49 no.8
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    • pp.821-829
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    • 2006
  • Hemophilia is the most common coagulation disorder. It has a long history. Hemophilia A is caused by FVIII gene mutation, and hemophilia B by FIX gene mutation. Those genes are located on X chromosome long arm. Bleedings in hemophiliacs predominantly occur in joints and muscles. Because those site are insufficient in tissue factor to induce hemostasis. Among joints knee, ankle and elbow are most frequently affected because their synovial structure is vulnerable to injury compared to other joints. Hemophilia is diagnosed with factor assay. Severe hemophilia is below 1% of FVIII : C, moderate between 1% and 5%, mild over 5%. Carrier detection and prenatal diagnosis have been conducted with RFLP-based linkage analysis and DNA sequencing. Mainstay of treatment is factor replacement therapy so far. Bleedings can be controlled by infusion of factor concentrates. Hemophilc arthropathy and muscle contracture are representative sequelae. Complications of facotor replacement therapy are inhibitor development and infections. Hemophiliacs with inhibitor should be managed with large dose factor concentrate, bypassing agent, ITI and immunosuppression. Ultimately, hemophilia could be cured by gene therapy.

Development of Critical Heat Flux Correction Factor for Water under Flow Oscillation Conditions

  • Kim, Yun-Il;Baek, Won-Pil;Chang, Soon-Heung
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.11a
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    • pp.242-247
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    • 1996
  • Flow oscillations in boiling channels induces a drastic reduction of the (critical heat flux) CHF or premature burnout. However, most of CHF works and correlations have been focused on stable flow conditions without considering flow oscillation. Therefore to improve the understanding on flow oscillation CHF, in this paper a new CHF correction factor to predict the CHF values under flow oscillation conditions has been developed from 126 experimental data. Also to investigate the dominant factor on flow oscillation CHF parametric trends are analyzed by using the developed correction factor. The overall mean accuracy ratio of the developed correction factor is 1.033 with a standard deviation of 0.195. The RMS errors 0.198. Its assessment shows that the predictions agree well with the experimental data within 25% error bounds.

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