• The Journal of the Korea Contents Association
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• v.14 no.5
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• pp.224-234
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• 2014

This study designed to nursing student's image of professional nurse before clinical practice using Q-methodology. Using Q-methodology, 43 nursing student sorted 34 statements selected professional nurse type. The statement positions on the sorting continuum were scored from +4(representing the highest level of agreement) through 0(at the neutral position on the continuum) through -4(representing the highest level of disagreement). Factor analysis of the data was undertaken using PC QUANL software to determine if any patterns were discernible. The three factors extracted eigenvalues greater than 1.0 and explained approximately 53.94% of the variation in responses(41.63, 7.41 and 4.9% respectively). The categories were labeled 'Nightingale's nursing philosophy type', 'Consideration of patient type' and 'Self-development type'. Twenty-two students who located to factor 1 "Nightingale's nursing philosophy type". Eleven students who located to factor 2 "Consideration of patient type". Three students sho located to the factor 3 "Self-development type". The significant differences found in the subjective structure of nursing student's image of professional nurse. The study results can be utilized in both an effective nursing education and clinical practice.

• The Journal of the Korea Contents Association
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• v.14 no.11
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• pp.175-185
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• 2014

This study is to develop a fatigue scale for the private security guard for a private security guard to effectively manage fatigue were tested for validity and reliability. To achieve that, this study employed purposive sampling to draw 300 samples among private security guards working for the security firms registered in Seoul District Police Office as of 2014, and used 259 samples for final analysis. Fatigue scale was developed on the basis of the scale development methods and procedures in previous studies. For data processing, SPSSWIN 18.0 program was applied to conduct exploratory factor analysis, reliability analysis, and correlation analysis, and AMOS 18.0 program was employed to conduct confirmatory factory analysis. This study came to the following conclusion. First, the validity of the fatigue measurement tool was high. In other words, content validity was high, and construct validity was also high. The factor loading of exploratory factor analysis was .452, and the standard value of confirmatory factor analysis was .403. Therefore, the tool satisfied the basis value of fit index. The sub categories of fatigue, finally drawn from validity test, were mental fatigue, nervous system dysfunction, physical deformity, and exhaustion. Secondly, the reliability of the fatigue measurement tool was high. In other words, according to item analysis, the correlation between items and their sub categories, and between items and total score was more than .602, relatively high. And the reliability coefficient (Cronbach's ${\alpha}$) was high, or more than .658. Fatigue Scale tool will be developed by private security guards in the present study is to measure the validity and reliability verification is clearly tired of the private security guards than the tools that are used in other studies in the existing area.

• Journal of Korean Academy of Nursing
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• v.26 no.1
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• pp.94-106
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• 1996

Nursing literature suggests that the self-concept of nurses gives an important implications to educators and administrators as well as clinicians for their professional development. With a view to exploring how nurses view themselves, the Professional Self-Concept of Nurses Instrument (PSCNI) using 27 Likert items was developed by Arthur in Australia in 1990. This study is an extension of the PSCNI using Korean samples with some modifications. A convenience sample was drawn from 800 nurses working in three university hospitals in Seoul ; three university hospitals in Kyonggi-do and a university hospital and a psychiatric hospital in Kangwon-do. Seven hundred questionnaires were analyzed using the statistical analysis system(SAS). The reliability of the scale was tested by test-retest and Cronbach's alpha. Differences in the PSCNI, which are closely related to demographic variables, were examined by t-test, ANOVA and the Duncan's multiple range test. Factor analysis was employed so as to examine component factors. The results are summarized as follows : 1. The test-retest reliability of the PSCNI was .79 and Cronbach's alpha was .85. Item correlations with total revealed consistent correlations and subscale reliability varied from .49 to .85. 2. The average score of PSCNI was 75.21 and average item score was 2.79. 3. Twenty four items were derived from the PSCNI 27 items and these items clustered in three component factors. The cumulative percent of variance was 38.12％ and for factor 1 was 22.81％, for factor 2, 9.79％ and for factor 3, 5.51％ respectively 4. A comparison of the scores for the dimensions of the PSCNI shows a relative difference in terms of mean item scores and in descending order, professional practice（m=2.83）, communication （m=2.82） and satisfaction（m=2.70）. 5. Professional self-concept of nurses was found to vary significantly according to age（P=.0001）, religion（P=.0001）, academic background（P= .0109）, marital status（P=.0001）, career（P= .0001） and position（P=.0001）. In conclusion, there was a correlation between professional self-concept of nurses, and life and work variables. This study provides an important message for administrators and nurse educators by highlighting factors which can be addressed by education programs, staff development and appraisal. While the test results largely confirm the Australian and Canadian tests, further research is necessary to improve the cumulative percent of variance instead of applying Arthur's PSCNI directly to Korean nurses.

• Korean Journal of Cleft Lip And Palate
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• v.4 no.1
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• pp.13-26
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• 2001

Cleft lip and/or palate is the congenital orofacial malformation most commonly occurred in humans, The disease is multifactorial and is probably caused by genetic and/or environmental factors, So, there are many problems in research concerning etiology and in treatment of the disease, Even the most practiced and sophisticated methods of surgical repair are necessarily followed by scar contraction and fibrosis, which result in skeletal defects, dental abnormalities, cosmetic disfigurement, and speech impairment, As a result, Fetal surgery can be considered but practiced rarely when the deformity is not fatal to life, And treatment of cleft palate is performed in the form of medicine projection into uterus in animal experiments, Many studies show that growth factor and its receptor emerge from the developing palate; and the epidermal growth factor receptors have a important role in craniofacial development and in palatal fusion, The palatal morphogenesis of the avine is different from the mammal's; it takes the form of physiologic cleft palate, Recently, cleft palate fusion experiment was performed when the avine were in the period of palate formation through the exogenous TGF-β3 addition, and it showed that the exogenous TGF-β3 makes fusion of divided palate through certain process when cleft palate is occurred in palatal formation, In this study, I had the conformation of the fusion of cleft palate through the addition of TGF-β in case of chicken embryo, and observed the effect of TGF-β in EGF receptor distribution, And the following is the results of this study, 1. In case of the TGF-βl and β3 addition group, there was the decrease of EGFR(Epidermal Growth Factor Receptor) immunoreactivity in mesenchymal cells beneath the medial edge epithelium and also in epithelial mesenchymal interface which is between medial edge epithelium and nasal septum in 72 hours, 2, The immunoreactivity of the control group resembles that of normal chicken embryo palate in development, 3. In the view through fluorescence confocal microscopy, there was confluence in TGF-β3 addition group, This shows that the confluence induced by exogenous TGF-β3 is related to EGFR expression in palate of chicken embryo, which is a physiologic cleft palate model.

• KDI Journal of Economic Policy
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• v.26 no.2
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• pp.249-280
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• 2004

This paper analyzes the industrial growth of Korea in the 1990s and its relationship with the nation's export performance. The result shows that total factor productivity (TFP) played a significant role in the growth of some industries, where in particular a sharp increase in TFP was observed in the electrics and electronics industry and the automobile industry in the late 1990s. While CEPII RCA indexes for the Korean industries such as IT industry and automobile industry significantly increased since 1998, only limited evidence was found that TFP or TFI influenced RCA. Investigating Korea's export performance in the Northeast Asian context, this paper shows that, in the 1990s, the growth of Korea's exports to Japan was led by industries that recorded relatively fast growth in total factor input (TFI). In contrast, that to China was almost equally contributed by industries that experienced relatively fast growth in TFP or TFI. This paper also investigates competition between Korea and China, and Korea and Japan in the world market. The competition between Korea and China was relatively stronger for the Korean industries to whose growth TFI made a more significant contribution. While no decisive evidence is found for the relationship between TFP growth in Korean industries and their competition against Japan in the world market, it is revealed that the competition between Korea and Japan became less intense for the Korean industries to whose growth TFI made a stronger contribution. In this regard, the paper supports the view of 'nut-cracking' that the Korean economy has lost its competitiveness in the sectors where it maintained comparative advantage, but failed to catch up more advanced countries such as Japan by gaining competitiveness in more capital or technology intensive sectors.

• Asian-Australasian Journal of Animal Sciences
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• v.22 no.4
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• pp.471-482
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• 2009

Nutrient availability may control muscle growth directly and indirectly through its influence on regulatory factors. We analyzed the effects of nutrient availability on the breast muscle insulin-like growth factor system. Real time RT-PCR was used to quantify the level of transcription in breast muscle from Langshan (LS) layer and Arbor Acres (AA) broiler chickens subjected to different feeding regimens during embryonic and postnatal development. The AA chickens were fed AA diet (AA, control group) while the LS chickens were either fed LS diet (LL) or AA diet (LA). According to our results, insulin-like growth factor (IGF)-II (embryonic day 16 (E16) - postnatal day 42 (P42)), IGF-I receptor (IGF-IR, E18-P42), and IGF binding protein (IGFBP)-2 (E18-P42), -5 (E16-P14), -7 (E12-P0), and -3 (E12-P0) were positively correlated with IGF-I, while IGFBP-3 (P0-P28) was negatively correlated with IGF-I. In comparison, IGF-IR (E18-P42), IGFBP-2 (E18-P42), IGFBP-5 (E14-P0), and IGFBP-3 (E16-P0) were positively correlated with IGF-II, while IGF-IR (E10-E16) and IGFBP-3 (P0-P28) were negatively correlated with IGF-II. Moreover, IGFBP-2 (E16-P42), -7 (E10-E16), and -3 (E10-E16) were positively correlated with IGF-IR, while IGFBP-3 (P0-P28) was negatively correlated with IGF-IR. Finally, IGFBP-7 (E12-P0) was positively correlated with IGFBP-3, while IGFBP-2 (P0-P28) and -7 (P0-P42) were negatively correlated with IGFBP-3. Overall, the AA chickens exhibited higher levels of IGF-I, IGF-IR, and IGFBP-2 mRNA expression than the LL chickens, while the opposite was true for IGFBP-7. No strain differences in IGF-I, IGF-IR, and IGFBP-7 mRNA expression were detected between LA and AA chickens; however, a strain difference was observed for IGFBP-2. LA chickens exhibited higher levels of IGFBP-2 than LL chickens, while the opposite was true for IGFBP-7. Our data show the first evidence that certain genes may be correlated during specific developmental periods and that strain differences in the expression of those genes in LS and AA chickens are due to differential responses to the same diet.

• Journal of Korean Academy of Nursing
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• v.29 no.6
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• pp.1365-1378
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• 1999

This study is a methodological research study to develop an instrument to measure in patients with cancer and to test the validity and reliability of the instrument. The research procedure was as follows : 1) The first step was to develop conceptual framework based on a comprehensive review of the literature and in-depth interviews with patients with cancer. This conceptual framework was organized in to three dimensions (the intrapersonal dimension, the significant-other and context related dimension, the transcendental dimension). Initially 59 items were adopted. 2) These items were analyzed through the index of content validity(CVI) and 53 items were selected which met more than 80% on the CVI. 3) The pretest was carried out with 87 patients with cancer. After the pretest results were analyzed by item analysis, 44 items were selected. A second test of content validity was conducted and 6 items were eliminated considering the 80% CVI. 4) To test for reliability and validity, data collection was done during the period from January 25, 1999, to February 26, 1999. The subjects for the test were 160 patients with cancer and 185 healthy persons. analysis, item analysis and multitrait-multimethod method to analyze validity. The findings are as follows : 1) The Cronbach's alpha coefficient for internal consistency was .92 for the total 38 items and .79, .82, .85, for the three dimensions in that order. 2) The item analysis was based on the corrected item to total correlation coefficient( .30 or more) and information about the alpha estimate if this item was dropped from the scale. 3) As a result of the initial factor analysis using principal component analysis and varimax rotation, one item was deleted because of factor complexity (indiscriminate factor loadings). In the secondary factor analysis, 7 factors with eigenvalue of more than 1.0 were extracted and these factors explained 56 percents of the total variance. The seven factors were labeled as 'family relationship', 'emotional condition', 'physical discomfort', 'meaning and goal of life', 'contextual stimuli', 'change of body image', 'guilt feelings'. 4) The convergence effect between this instrument and the life satisfaction scale was identified and there was significant positive correlation(r= .52, p= .00). The discriminant validity between this instrument and the depression scale(CES-D) was tested and there was significant negative correlation(r= -.50, p= .00). The instrument for accessing the suffering of patients with cancer developed in this study was identified as a tool with a high degree of reliability and validity. In this sense, this tool can be effectively utilized for assessment in caring for patients with cancer.

• Journal of the Korean Institute of Landscape Architecture
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• v.27 no.4
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• pp.1-12
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• 1999

This study aims to find basic data for using the quantitative assessment of the sustainability and establishing the systematic index of the planning for local cities to consider the environmentally sound and sustainable development. The research designs to review professional responding to surveys preceded by separate questionnaires and interviews from book reviews, and suggests to make an assessment model of the sustainability for local cities. The research found consequently as follows. Firstly, the research survey items were decides totally 52, grouped 9 assessmental issues and distributed under 4 assessmental domains for the sustainability from the references of book reviews. Secondly, the research result concentrated on the followings from the professional responding to surveys. 1. A most influent factor is the distribution of animals and plants in a nature domain. The next influent factors are the ratio of mass-transportation systems, the numbers of the species of animals and plants, the acreage of conservative forestry, the numbers of reused water resources, and the usage number of water supply, orderly in the nature domain. 2. A most influent factor is the usage number of synthetic detergents in a pollution domain. The next influent factors are the volume of waste water, the number of registered vehicles, the degree of soil pollution, and the charge of development imposition, orderly in the pollution domain. 3. A most influent factor is the acreage of athletic facilities, in an urban domain. the next influent factors are the acreage of recreational facilities, the number and acreage of cultural assets, the number of cultural facilities, the acreage of landscape conservation area, the charge of cultural asset management, orderly in the urban domain. 4. A most influent factor is the number of waste disposal facilities in a participation domain. The next influent factors are the capacity of reused waste, the usage of synthetic detergents, the ratio of waste water disposal, orderly in the participation domain. 5. A most contributed influent domain to the assessment of the sustainability for local cities is the urban domain. The next influent domains are nature domain, participation domain, and pollution domain, orderly in the contribution of the assessment of the sustainability. But, the pollution domain is little relationship with the sustainability. Therefore, it is clear that the abundant greens and the improved level of culture are dominant influences on the sustainabiligy, as like improving the ratio of roadside trees, the acreage of parks, and enlarging the number of cultural facilities.

• Korean Journal of Environmental Biology
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• v.36 no.2
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• pp.131-139
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• 2018

The warming of water as a result of climate change affects fish habitat. Variations in water temperature affect fish physiology almost totally. The rise in water temperature due to climate change leads to hypoxia following decreased oxygen solubility and decreased binding capacity of oxygen-carrying hemoglobin. This study was conducted to evaluate the health status of Atlantic salmon (Salmo salar) fry at elevated water temperatures($20^{\circ}C$) compared with optimum water temperature ($15^{\circ}C$). The method facilitated the detection of biomarker genes using NGS RNAseq analysis and evaluation of their expression pattern using RT-qPCR analysis. The biomarker genes included interferon alpha-inducible protein 27-like protein 2A transcript variant X3, protein L-Myc-1b-like, placenta growth factor-like transcript variant X1, fibroblast growth factor receptor-like 1 transcript variant X1, transferrin, intelectin, thioredoxin-like, c-type lectin lectoxin-Thr1-like, ladderlectin-like and calponin-1. The selected biomarker genes were sensitive to changes in water temperature based on NGS RNAseq analysis. The expression patterns of these genes based on RT-qPCR were similar to those of NGS RNAseq analysis.

• Korean Journal of Clinical Laboratory Science
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• v.36 no.2
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• pp.163-172
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• 2004

Mast cells (MCs) have been implicated in the pathogenesis of tissue fibrosis. However, the role of MC in the development of liver fibrosis has not been fully elucidated. Stem cell factor (SCF) is known to recruit MCs to the liver following injury as it induces mast cell proliferation, survival and differentiation from resident tissue precursors. This study examines the interaction between activated hepatic stellate cells (HSCs) and MCs in rat fibrotic liver, and SCF production by HSCs during culture in vitro. Rats were studied 4, 7, 14 and 21 days after bile duct ligation (BDL). Fibrogenesis was assessed by a measurement of collagen stained with sirius red F3B. Activated HSCs and MCs were identified by ${\alpha}$-smooth muscle actin (${\alpha}-SMA$) immunohistochemical and alcian blue staining and measured by a computerized image analysis system. SCF production was determined in rat HSC cultures using Western blotting. Mild fibrotic changes were noted in BDL rat livers as early as 4 days after induction of cholestasis. Significant expansion and organization of fibrous tissue has occurred in day 14 BDL rats which progressed to bridging fibrosis by day 21. In BDL rats, both a large number of activated HSCs and MCs were detected in portal tracts and fibrous septa. Both area of activated HSCs infiltration and density of MCs were significantly higher in all BDL group compared with Shams. In BDL rats, both areas of activated HSCs infiltration and density of MCs were no significant difference between day 4 and 7 and were significantly higher in day 14. However, the areas of activated HSCs infiltration were significantly lesser in day 21 and the densities of MCs were significantly higher in day 21 compared with day14 BDL. In BDL rats, both areas of activated HSCs infiltration and density of MCs were highly correlated with areas of fibrosis. Western blotting showed that SCF protein was consistently produced in activated HSCs by culture on plastic and freshly isolated HSCs expressed relatively little 30kD SCF compared to late primary culture activated HSCs (day 14) and passaged HSCs. These results suggest that HSCs activated in vitro produce SCF, and may play an important role in recruiting mast cells to the liver during injury and fibrosis.