• Title/Summary/Keyword: Development factor

Search Result 10,328, Processing Time 0.044 seconds

Research on the Impact of Logistics Industry Efficiency and Agglomeration Effect on Import and Export Trade in Korea

  • Cheng, Wen-Si
    • Journal of Korea Trade
    • /
    • v.25 no.5
    • /
    • pp.93-109
    • /
    • 2021
  • Purpose - The logistics industry is often featured by its location relevance and industrial concentration. Industrial concentration is conducive to the effective transmission of information by reducing transaction costs and improving transaction efficiency, thus promoting the development of trade. The main purpose of this paper is to measure the spatial total factor productivity and location quotient of the logistics industry in Korea, and to study the impact of the logistics industry efficiency and agglomeration effect on import and export trade in Korea. Design/methodology - First, used the spatial stochastic frontier method to measure the spatial total factor productivity of the logistics industry in Korea, this serves as the efficiency index of the logistics industry in various regions of Korea. Second, calculated the location quotient (LQ) of the logistics industry to measure the industry's concentration degree. Third, employed a spatial econometric model to analyze the impacts of factors such as the efficiency and concentration levels of the logistics industry on import and export trade in Korea. Findings - This study's main findings can be summarized as follows: this study found that the overall efficiency of the logistics industry in Korea needs to be improved, even though it showed an upward trend in all regions of the country; Moreover, the agglomeration level of Korea's logistics industry needs to be improved; Finally, the positive spatial correlation and industrial agglomeration effect of Korea's logistics industry had a positive impact on the country's import and export trade. Originality/value - This study is innovative in terms of research perspective and methods. Most of the previous studies have measured the development level of the logistics industry using the logistics performance index (LPI), Fewer studies have assessed through the spatial total factor productivity and location quotient of the logistics industry in Korea to measure the efficiency index of the logistics industry in various regions of Korea and concentration degree, as well as there was almost no study on the impact of logistics industry efficiency and agglomeration effect on import and export trade in Korea. This study addresses this limitation by analyzing the impacts of the efficiency and agglomeration effect of the logistics industry on import and export trade in Korea.

Transcriptome profiling and identification of functional genes involved in H2S response in grapevine tissue cultured plantlets

  • Ma, Qian;Yang, Jingli
    • Genes and Genomics
    • /
    • v.40 no.12
    • /
    • pp.1287-1300
    • /
    • 2018
  • Hydrogen sulfide ($H_2S$), a small bioactive gas, has been proved functioning in plant growth and development as well as alleviation of abiotic stresses, which including promoting seed germination, accelerating embryonic root growth, regulating flower senescence, inducing stomatal closure, and defending drought, heat, heavy metals and osmotic stresses etc. However, the molecular functioning mechanism of $H_2S$ was still unclear. The primary objective of this research was to analyze the transcriptional differences and functional genes involved in the $H_2S$ responses. In details, 4-week-old plantlets in tissue culture of grapevine (Vitis vinifera L.) cultivar 'Zuoyouhong' were sprayed with 0.1 mM NaHS for 12 h, and then transcriptome sequencing and qRT-PCR analysis were used to study the transcriptional differences and functional genes involved in the $H_2S$ responses. Our results indicated that 650 genes were differentially expressed after $H_2S$ treatment, in which 224 genes were up-regulated and 426 genes were down-regulated. The GO enrichment analysis and KEGG enrichment analysis results indicated that the up-regulated genes after $H_2S$ treatment focused on carbon metabolism, biosynthesis of amino acids, and glycolysis/gluconeogenesis, and the down-regulated genes were mainly in metabolic pathways, biosynthesis of secondary metabolites, and plant hormone signal transduction. Analyzing the transcription factor coding genes in details, it was indicated that 10 AP2/EREBPs, 5 NACs, 3 WRKYs, 3 MYBs, and 2 bHLHs etc. transcription factor coding genes were up-regulated, while 4 MYBs, 3 OFPs, 3 bHLHs, 2 AP2/EREBPs, 2 HBs etc. transcription factor coding genes were down-regulated. Taken together, $H_2S$ increased the productions in secondary metabolites and a variety of defensive compounds to improve plant development and abiotic resistance, and extend fruits postharvest shelf life by regulating the expression of AP2/EREBPs, WRKYs, MYBs, CABs, GRIP22, FERRITINs, TPSs, UGTs, and GHs etc.

Priority for Developing Emission Factors and Quantitative Assessment in the Forestry Sector (산림부문의 국가온실가스 배출·흡수계수 개발 필요 우선순위 및 정량평가 방법론)

  • Han, Seung Hyun;Lee, Sun Jeoung;Chang, Hanna;Kim, Seongjun;Kim, Raehyun;Jeon, Eui-Chan;Son, Yowhan
    • Journal of Climate Change Research
    • /
    • v.8 no.3
    • /
    • pp.239-245
    • /
    • 2017
  • This study aimed to suggest priority for developing emission factor (EF) and to develop the methodology of quantitative assessment of EF in the forestry sector. Based on the stock-difference method, 17 kinds of EFs (27 EFs based on forest types) were required to calculate the carbon emission in the forestry sector. Priority for developing EFs followed the standards, which is a development plan by the government agency, importance of carbon stock for greenhouse gas, and EFs by the species. Currently, the most urgent development of EFs was carbon fraction in biomass and carbon stock in dead wood. Meanwhile, the quantitative assessment of EF consisted of 7 categories (5 categories of compulsory and 2 categories of quality evaluation) and 12 verification factors. Category in compulsory verification consisted of administrative document, determination methodology of emission factors, emission characteristic, accuracy of measurement and analysis, and data representative. Category in quality evaluation consisted of data management and uncertainty estimates. Based on the importance of factors in the verification process, each factor was scored separately, however, the score needs to be coordinated by the government agency. These results would help build a reliable and accurate greenhouse gas inventory report of Korea.

The Effects of Productization, Organizational, Overseas Market Adaptation Competences on Export Performance: Focus on Korean Electromagnetic Wave Shielding Firms (기업의 제품화 역량, 조직역량, 해외시장 적응역량이 수출성과에 미치는 영향: 전자파 차폐 기업을 중심으로)

  • Park, Won-Cheol;Oh, Ka-Young
    • Asia-Pacific Journal of Business
    • /
    • v.11 no.3
    • /
    • pp.307-344
    • /
    • 2020
  • Purpose - The purpose of this study is to examine effects of productization and organizational competences on export performance of electromagnetic shielding companies and to analyze moderating effects of overseas market adaptation competences. For this, hypotheses were established by reviewing previous studies and an empirical analysis was conducted for testing. Design/methodology/approach - For this study, a survey was conducted for workers at electromagnetic shielding companies and 250 valid responses out of 300 questionnaires were aquired. A frequency analysis of related variables was conducted. Through an exploratory factor analysis, validity and reliability tests of measuring tools were conducted and a descriptive statistics was analyzed for collected data result and hypotheses testing. Findings - A correlation analysis was conducted to examine relationships among variables. Construct, convergent and discriminant validities were analyzed after a confirmatory factor analysis and a multi-group confirmatory factor analysis. Finally, with a verified model, the hypotheses and the moderating effects were tested. The results are as follows: First, the productization competence has a positive effect on export performance; Second, the organizational competence has a positive effect on export performance. Especially, the organizational competence has more effect on export performance than the productization competence. Although a development of new technology and product is important in terms of performance, along with these competences, a way of acquiring new skills and knowledge, and internalization and adaptation in organizations have more effect on export performance. Third, overseas market adaptation competence moderates effects of organizational and productization competences. Research implications or Originality - It is necessary to seek out opportunities for workers to participate in actively, such as conferences and seminars, to strengthen organizational competence. It is strongly believed that a constant development of high quality product will contribute to export performance. Lastly, in a policy level, supports on SMEs by governments are to be strengthened by providing with finance and human resource.

Risk assessment and evaluation of epidermal growth factor (EGF) transgenic soybean: responses of Cyprinus carpio fed on EGF transgenic soybean

  • Oh, Sung-Dug;Min, Seok-Ki;Kim, Jae Kwang;Park, Jung-Ho;Kim, Chang-Gi;Park, Soo Yun
    • Korean Journal of Agricultural Science
    • /
    • v.47 no.4
    • /
    • pp.815-827
    • /
    • 2020
  • The epidermal growth factor (EGF) transgenic soybean was developed and biosynthesis of human epidermal growth factor (hEGF) in soybean seeds was confirmed. Also, EGF transgenic soybean were found to contain a herbicide resistance selectable marker by introduction of phosphinothricin acetyltransferase (PAT) gene from the Streptomyces hygroscopicus. For biosafety assessment, the EGF transgenic soybean expressing the EGF biosynthesis gene EGF and herbicide resistant gene PAT was tested to determine effects on survival of Cyprinus carpio, commonly used as a model organism in ecotoxicological studies. C. carpio was fed 100% ground soybean suspension, EGF soybean or non-genetically modified (GM) counterpart soybean (Gwangan). Gene expression of EGF soybean was confirmed by PCR and ELISA to have EGF/PAT. Feeding test showed that no significant differences in cumulative immobility or abnormal response between C. carpio samples fed on EGF soybean and non-GM counterpart soybean. The 48 h-EC50 values of the EGF and non-GM soybean were 1,688 mg·L-1 (95% confidence limits: 1,585 - 1,798 mg·L-1) and 1,575 mg·L-1 (95% confidence limits: 1,433 - 1,731 mg·L-1), respectively. The soybean NOEC (no observed effect concentration) value for C. carpio was suggested to be 625 mg·L-1. We concluded that there was no significant difference in toxicity for non-target organisms (C. carpio) between the EGF soybean and non-GM counterparts.

Aster saponin A2 inhibits osteoclastogenesis through mitogen-activated protein kinase-c-Fos-NFATc1 signaling pathway

  • Su, Xiang-Dong;Yang, Seo Y;Shrestha, Saroj K;Soh, Yunjo
    • Journal of Veterinary Science
    • /
    • v.23 no.4
    • /
    • pp.47.1-47.11
    • /
    • 2022
  • Background: In lipopolysaccharide-induced RAW264.7 cells, Aster tataricus (AT) inhibits the nuclear factor kappa-light-chain-enhancer of activated B cells and MAPKs pathways and critical pathways of osteoclast development and bone resorption. Objectives: This study examined how aster saponin A2 (AS-A2) isolated from AT affects the processes and function of osteoclastogenesis induced by receptor activator of nuclear factor kappa-B ligand (RANKL) in RAW264.7 cells and bone marrow macrophages (BMMs). Methods: The cell viability, tartrate-resistant acid phosphatase staining, pit formation assay, polymerase chain reaction, and western blot were carried out to determine the effects of AS-A2 on osteoclastogenesis. Results: In RAW264.7 and BMMs, AS-A2 decreased RANKL-initiated osteoclast differentiation in a concentration-dependent manner. In AS-A2-treated cells, the phosphorylation of ERK1/2, JNK, and p38 protein expression were reduced considerably compared to the control cells. In RAW264.7 cells, AS-A2 suppressed the RANKL-induced activation of osteoclast-related genes. During osteoclast differentiation, AS-A2 suppressed the transcriptional and translational expression of NFATc1 and c-Fos. AS-A2 inhibited osteoclast development, reducing the size of the bone resorption pit area. Conclusion: AS-A2 isolated from AT appears to be a viable therapeutic therapy for osteolytic illnesses, such as osteoporosis, Paget's disease, and osteogenesis imperfecta.

A study for the development and validation of a dog owner's parenting behavior scale (반려견 보호자 양육행동 척도 개발 및 타당화 연구)

  • Shim, Hae Mee;Park, Heejoon;Han, Jin Soo;Lee, Donghyuck
    • Korean Journal of Veterinary Research
    • /
    • v.62 no.3
    • /
    • pp.21.1-21.10
    • /
    • 2022
  • With the increasing population of companion dogs, the social cost derived from their behavioral problems is increasing. Therefore, it is important to understand the environment to provide experience for dogs via interactions with their owners to prevent and solve these problems. The parenting behavior of dog owners as an environmental factor has a profound impact on the behavior development of dogs, as does the parenting behavior on children. Therefore, this study aimed to develop a scale to assess the dog owner's parenting behavior. Exploratory factor analysis involving 300 participants resulted in a scale with four subscales, Positive Education, Involvement of Socialization, Intimacy, and Stable Responses, and 19 items. Confirmatory factor analysis was then performed to verify its reliability and validity. The result of parenting behaviors assessed by this scale was significantly different between a group with dogs with problematic behavior (n = 141) and those without (n = 159). Overall, a dog owner's parenting behavior involves affection and control aspects, but the role required specifically in the control aspect is distinguished from the parenting behavior with children. The findings in the present study will provide dog owners with effective education that will help prevent dogs from developing behavioral problems.

Leptomeningeal Metastasis in Gliomas : Clinical Characteristics and Risk Factors

  • Jeyul Yang;Ji-Woong Kwon;Sang Hoon Shin;Heon Yoo;Kyu-Chang Wang;Sang Heyon Lee;Ho-Shin Gwak
    • Journal of Korean Neurosurgical Society
    • /
    • v.66 no.4
    • /
    • pp.465-475
    • /
    • 2023
  • Objective : Our objective is to analyze the occurrence, clinical course and risk factors for glioma patients with leptomeningeal metastasis (LM) according to different metastasis patterns and clinical variables. Methods : We retrospectively reviewed data from 376 World Health Organization (WHO) grade II-IV adult glioma patients who were treated in the National Cancer Center from 2001 to 2020. Patients who underwent surgery at other institutions, those without initial images or those with pathologically unconfirmed cases were excluded. LM was diagnosed based on magnetic resonance imaging (MRI) findings or cerebrospinal fluid (CSF) cytology. The metastasis pattern was categorized as nodular or linear according to the enhancement pattern. Tumor proximity to the CSF space was classified as involved or separated, whereas location of the tumor was dichotomized as midline, for tumors residing in the thalamus, basal ganglia and brainstem, or lateral, for tumors residing in the cerebral and cerebellar hemispheres. Results : A total of 138 patients were enrolled in the study. A total of 44 patients (38%) were diagnosed with LM during a median follow-up of 9 months (range, 0-60). Among the clinical variables, tumor proximity to CSF space, the location of the tumor and the WHO grade were significant factors for LM development in univariate analysis. In multivariate analysis, the midline location of the tumor and WHO grade IV gliomas were the most significant factor for LM development. The hazard ratio was 2.624 for midline located gliomas (95% confidence interval [CI], 1.384-4.974; p=0.003) and 3.008 for WHO grade IV gliomas (95% CI, 1.379-6.561; p=0.006). Conclusion : Midline location and histological grading are an important factor for LM in glioma patients. The proximity to the CSF circulation pathway is also an important factor for WHO grade IV glioma LM. Patients carrying high risks should be followed up more thoroughly.

Development and validation of the Korean Game Addiction Scale for Children and Adolescents (한국형 아동/청소년 게임 중독 척도의 개발 및 타당화)

  • Kim, Kyo-Heon;Choi, Hoon-Seok;Kwon, Sun-Jung;Ryong, Joung-Soon
    • Korean Journal of Health Psychology
    • /
    • v.14 no.3
    • /
    • pp.511-529
    • /
    • 2009
  • The purpose of this study was to develop and validate Korean Game Addiction Scale for children and adolescents. Data from a representative sample of 3,115 children and adolescents residing in Korea were analyzed to identify the factor structure and reliability of the scale. In addition, criterion-related evidence of validity (concurrent and convergent) was examined. Consistent with our theoretical assumptions, the Korean Game Addiction Scale revealed a stable higher order factor structure (second order-one factor, first order-seven factors), and the reliability of the scale was high (average Cronbach's alpha = .84, six week test-retest reliability = .75). The scale was also showed high levels of concurrent and convergent validity. Implications of the findings and directions for future research on game addiction are discussed.

Development of Evaluation Items for Physical Therapy Clinical Practice

  • Seung-Hwa Jung;Joo-hee An;Seul-Ki Han;Dae-Sung Park;Cheong Hoon Kim
    • Physical Therapy Rehabilitation Science
    • /
    • v.13 no.1
    • /
    • pp.71-77
    • /
    • 2024
  • Objective: The purpose of this study is to present practice guidelines on what physical therapy students must learn during clinical training and how to evaluate them. Design: Design & development research Methods: A Delphi survey was conducted with 16 experts. Experts who participated in the study were asked to respond to 15 musculoskeletal system, 14 nervous system, and 12 physical factor therapy items through an online survey with a 5-point Likert score for each item regarding suitability and importance. Results: As a result of defining the core basic physical therapy skills that students in the Department of Physical Therapy must learn through clinical practice and in the process of evaluating them, there was a strong opinion that among the specific fields of physical therapy, evaluation items related to the musculoskeletal system, nervous system, and cardiorespiratory system were important. On the contrary, physical factor therapy showed poor results. Conclusions: In a previous study, opinions on the specialty of physical therapists were collected from current physical therapists, and the field of physical factor therapy was evaluated low. I think this reflects the perception that treatment using electricity has been commonly used in the field of physical therapy for a long time and does not require deep expertise among clinicians. Physical therapy clinical practice guidelines and efficient operation plans for clinical practice were presented. Through this, it can be usefully applied in hospitals where physical therapy students undergo clinical training in the future.