• Title/Summary/Keyword: Development factor

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Development and Characterization of Mobile Transceiver for Millimeter-Wave Channel Sounding Measurement (밀리미터파 채널사운딩 측정을 위한 이동형 송수신 장치의 개발과 특성평가)

  • Jonguk Choi
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.24 no.3
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    • pp.35-40
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    • 2024
  • In this paper, the design, implementation, and analysis of a device capable of transmitting and receiving millimeter-wave signals and performing channel sounding measurements in atmospheric conditions at distances of up to approximately 10km outdoors are presented. The device is expected to be instrumental in studying the propagation characteristics of millimeter-wave frequencies. Utilizing data such as received power levels and power delay profiles (PDPs), comparisons with predicted values using path loss, K-factor, and other propagation models are facilitated. The mobile transceiver unit, integrated onto a vehicle platform, allows for flexible adjustment of transmitter and receiver positions, while synchronization issues with distance are mitigated using a rubidium atomic clock. Furthermore, automatic boresight alignment using scanning techniques is employed to locate the main sector of the antenna.

Development of a Job Stress Measurement Tool for Nursing Managers in Small and Medium-Sized Hospitals (중소병원 간호관리자의 직무 스트레스 측정도구 개발)

  • Kim, Gaeun;Han, Suk Jung
    • Korean Journal of Occupational Health Nursing
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    • v.33 no.3
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    • pp.95-108
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    • 2024
  • Purpose: This study aimed to develop a tool to measure the job stress of nursing managers in small and medium-sized hospitals and to evaluate its reliability and validity. Methods: DeVellis' eight steps scale development process was applied. The initial questions were developed through a literature review and in-depth interviews, and content validity was evaluated by 13 experts. Data were collected from 193 nursing managers at small and medium-sized hospitals in Korea, 193 through exploratory factor analysis (EFA), and 192 through confirmatory factor analysis (CFA). Results: The scale consisted of 27 final items and seven factors, with a total variance of 66.76%. The CFA results were x2 =642.56, p<.001, GFI=.80, CFI=.92, and Cronbach's ⍺ for the overall scale was .82. Conclusion: The scale showed satisfactory validity and reliability, confirming its potential to become an appropriate tool for measuring the job stress of nursing managers in small and medium-sized hospitals.

Oral squamous carcinoma cells stimulated by Porphyromonas gingivalis-derived lipopolysaccharide induce osteoclastogenesis through a paracrine mechanism

  • Bo Ram Keum;Soon Chul Heo;Hyung Joon Kim
    • International Journal of Oral Biology
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    • v.49 no.3
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    • pp.79-86
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    • 2024
  • Periodontal disease (PD) is strongly linked to increased risk of oral squamous cell carcinoma (OSCC); however, the specific mechanism through which the development of PD and OSCC is simultaneously promoted remains unclear. This study explored the impact of periodontal pathogens on OSCC progression and the contribution of periodontal pathogen-stimulated OSCC to PD development. The expression of osteoclastogenesis-inducing factors was assessed using quantitative reverse transcription polymerase chain reaction analysis following stimulation of OSCC with lipopolysaccharide (LPS) derived from the periodontal pathogen Porphyromonas gingivalis (Pg), a pathogen commonly responsible for PD. The cell counting kit-8 assay was used to determine the effects of Pg-LPS on OSCC proliferation and drug resistance to cisplatin and 5-fluorouracil. The effects of conditioned medium (CM) derived from Pg-LPS-stimulated OSCC on osteoclastogenesis was evaluated using tartrate-resistant acid phosphatase (TRAP) staining on bone marrow-derived macrophages (BMMs). Pg-LPS administration in SCC-25 and YD-8 OSCC cell lines induced a significant increase in receptor activator of nuclear factor kappa-B ligand mRNA expression; however, it did not affect cell proliferation. Treatment with CM derived from Pg-LPS-stimulated SCC-25 or YD-8 cells markedly enhanced the formation of TRAP-positive multinucleated cells during osteoclast differentiation of BMMs. Altogether, these findings demonstrate that Pg-LPS-stimulated OSCC promoted osteoclastogenesis through a paracrine mechanism.

Software Development Effort Estimation for Testing Data Analysis (테스팅 데이터 분석을 통한 소프트웨어 개발 노력 추정)

  • Jung, Hye-Jung;Yang, Hae-Sool
    • The KIPS Transactions:PartD
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    • v.11D no.1
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    • pp.173-182
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    • 2004
  • The research to estimate development effort of software has been progress. But, it is not easy gain that testing data for estimating of development effort. Also, if we get the testing data, it is important that analysis testing data. In this paper, we study the data analysis of software development effort using the 789 software development projects which developed in the 1990's. Software development scale and software development team site are various. Using the characteristic of factor, we have to study characteristic of data and we estimate the development effort step by step. First, we prove the difference of development effort with the 789 project data according to development type, development environment, the development language etc. Also, we execute the crosstabs analysis that team site and function point.

Expression of Anthrax Lethal Factor, a Major Virulence Factor of Anthrax, in Saccharomyces cerevisiae (Yeast내에서 탄저병 원인균인 Bacillus anthracis의 치사독소인 Lethal Factor 단백질 발현)

  • Hwang Hyehyun;Kim Joungmok;Choi Kyoung-Jae;Chung Hoeil;Han Sung-Hwan;Koo Bon-Sung;Yoon Moon-Young
    • Korean Journal of Microbiology
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    • v.41 no.4
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    • pp.275-280
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    • 2005
  • Anthrax is an infectious disease caused by the gram-positive bacterium, Bacillus anthracis. Anthrax toxin is a tripartite toxin comprising of protective antigen (PA), lethal factor (LF) and edema factor (EF). PA is the receptor-binding component, which facilitates the entry of LF or EF onto the cytosol. LF is a zinc-dependent metalloprotease, which is a critical virulence factor in cytotoxicity of infected animals. Therefore, it is of interest to develop its potent inhibitors for the neutralization of anthrax toxin. The first step to identify the inhibitors is the development of a rapid, sensitive, and simple assay method with a high-throughput ability. Much efforts have been concentrated on the preparation of powerful assays and on the screening of inhibitors using these system. In the present study, we have tried to construct anthrax lethal factor in yeast expression system to prepare cell-based high-throughput assay system. Here, we have shown the results covering the construction of a new vector system, subcloning of LF gene, and the expression of target gene. Our results are first trial to express LF gene in eukaryote and provide the basic steps in design of cell-based assay system.

The feasibility analysis for energy utilization of forest biomass (산림 바이오매스의 에너지 활용을 위한 타당성 분석)

  • Kang, Hyeun Koo;Park, Kee Chul;Kim, Lae Hyun
    • Journal of Energy Engineering
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    • v.23 no.1
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    • pp.7-20
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    • 2014
  • The optimal woodchip production system was developed and the production cost of a forest woodchip fuel was calculated for utilizing the pitch pine, which covers around 480,000ha nationwide. the marginal price of the woodchip fuel considering the factor of supply price, electricity and heat selling price as well as capacity factor were suggested and the economic sensitivity analysis was conducted for various scenario. The most important variable which determine economic feasibility was a fuel cost for the power generation facility. If the electricity price is higher than the current SMP(System Marginal Price) or the capacity factor is higher than 80%, there fully is a benefit to consume the woodchip fuels produced in the suggested production system in this study. In addition, the additional benefit becomes more obvious when considering REC(Renewable Energy Certificate) and CDM(Clean Development Mechanism). Therefore, it is strongly suggested for domestic power generation sector to utilize the forest biomass fuel to achieve the obligatory target of RPS.

A Study of Perceived Discomfort of The Patients Under Local Anesthesia - Centering Around the Development of Measures - (국소마취 수술환자의 불편감에 관한 연구 - 도구개발을 중심으로 -)

  • Lee, Gyeong Sug;Kim, Mi Ja;Park, Sun Mi;Paek, Sun Young;Lee, Yang Sug;Bae, Sang Do;Choi, Jung Hoon
    • Quality Improvement in Health Care
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    • v.7 no.1
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    • pp.6-17
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    • 2000
  • Background : This study was attempted to provide a basic information necessary for the development of measures evaluating perceived discomfort of the patients under local anesthesia and the developments of nursing intervention and nursing standard. Method : The study subjects were a convenience sample of 100 surgical patients under local anesthesia. The researcher visited the patients directly and explained the purpose of the study to them. Then they were asked to fill out questionnaires which were developed and structured by the researcher, under their prior permission. Out patient's data were collected at recovery room after operation. Results : Factor analysis on measures evaluating the patients under local anesthesia showed that the measures consisted of eight factors including "explanation", "humane treatment", "motion limitation", "pain", "no togetherness", "waiting", "the environment of operating room", and "unkindness". When analyzing each of the factors regarding their degree of contribution to perceived discomfort, it was found that "waiting" was highest in terms of the degree. According to general chara-cteristics of the sampled patients, the factor of "explanation" contributed to perceived discomfort more in male patients than female ones. Regarding parts of medical examination, the patients of otorhinolaryngology felt perceived discomfort most because of the factor of "pain". Conclusion : To relieve perceived discomfort the patients under local anesthesia require providing individually systematized nursing services which can reduce perceived discomfort according to each of the factors. In doing so, an unlimited attention and much effort should be given to realize CQI reaching the dimension of increase in comfort as well as decrease perceived discomfort.

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Effects of Diets Supplemented with Recombinant Epidermal Growth Factor and Glutamine on Gastrointestinal Tract Development of Early-weaned Piglets

  • Lee, D.N.;Chang, W.F.;Yu, I.T.;Chiou, Peter W.S.;Weng, C.F.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.4
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    • pp.582-589
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    • 2008
  • This study attempted to determine effects of recombinant porcine epidermal growth factor (pEGF) and glutamine (Gln) supplement on the growth performance and intestinal development of piglets weaned at 14 days of age. A total of ninety-six piglets were allotted to one of four dietary treatments which comprised inclusion of 1.0 mg pEGF supernatant/kg diet or 0.5% Gln both alone and in combination. Each treatment consisted of four replicates with six pigs per pen for a 28 days experimental period. Two pigs per replicate were sacrificed and gastrointestinal tract samples were collected on day 14. Data showed that dietary treatment failed to promote growth performance. On day 14, diets supplemented with pEGF elevated pancreatic chymotrypsin, jejunal alkaline phosphatase, sucrase, lactase and maltase activities (p<0.05), but failed to alter the small intestinal villus morphology, DNA, or protein content of gastrointestinal mucosa. Diets supplemented with Gln increased pancreatic chymotrypsin activity, tended to enhance the protein contents of gastric (p = 0.08) and jejunal mucosa (p = 0.09) but did not influence the serum IgA level or the enzyme activity in the gastrointestinal tract. On day 28, the diets supplemented with Gln increasedt (p<0.05) serum IgA and the proliferation of peripheral blood mononuclear cells by PHA stimulation. However, a combination of pEGF and Gln did not have a synergistic effect on these biomarkers in early-weaned piglets. The results demonstrate that diets supplemented with recombinant pEGF supernatant indeed improve intestinal digestive enzyme activity and diets supplemented with Gln increases the immune response in early-weaned piglets.

Analysis of determinant Factor for Industrial Complex Location (산업단지 입지 결정요인 분석)

  • Lee, Jae-Tak;Kim, Dong-Il
    • Journal of the Korea Convergence Society
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    • v.8 no.12
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    • pp.343-349
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    • 2017
  • In this study, the factors of the industrial complexes were analyzed in a comprehensive review, and the research model was developed and related variables were adopted to the purpose of this study. Also, the determinants of location are analyzed by three factors of infrastructure stabilization, industrial resource access, and residential neighborhood factors. For the analysis of this study, the hypothesis was analyzed through the path analysis of the SEM through the set hypotheses based on the research model. As a result of analysis, it is analyzed that TI factors and RA factors of infrastructure, IF group, are both influenced by industrial location. In addition, there is a statistically significant correlation in the analysis between the parameters of the NEF and the determinants of industrial location. The results of this study are expected to provide useful guidelines for industrial infrastructure development and industrial complex development projects at national and local government.

Effects of a Novel p.A41P Mutation in the Swine Myogenic factor 5 (MYF5) Gene on Protein Stabilizing, Muscle Fiber Characteristics and Meat Quality

  • Ryu, Youn-Chul;Lee, Eun-A;Chai, Han-Ha;Park, Jong-Eun;Kim, Jun-Mo
    • Food Science of Animal Resources
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    • v.38 no.4
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    • pp.711-717
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    • 2018
  • Myogenic factor 5 (MYF5) plays an important role in regulating skeletal muscle fiber characteristics, consequently affecting meat production and quality. We identified a novel p.A41P mutation in exon1 of the porcine MYF5 gene by direct sequencing. The mutation was predicted to be destabilizing in protein structure based on the resultant amino acid substitution. We estimated the significant substitution effect of p.A41P on the energy stabilization of Myf5 protein structure. Then, we demonstrated that the mutation in Yorkshire population significantly affected muscle fiber type I composition (p<0.05), loin-eye area of lean meat content (p<0.05) and filter-fluid uptake of meat quality (p<0.01). Furthermore, dominant effects significantly influenced total muscle fiber number (p<0.05). This study suggests that the novel p.A41P mutation in porcine MYF5 may be a valuable genetic marker to affect the muscle fiber characteristics and consequently improve meat production quality and quantity.