• Natural Product Sciences
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• v.14 no.4
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• pp.260-264
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• 2008

To find the antidiabetic activity of the tripterpenoid-rich fractions of Rubus coreanus (TRF-cor) and R. crataegifolius (TRF-cra) leaves or its main component niga-ichigoside $F_1$ (Niga-$F_1$), anti-hyperglycemic and antihyperlipidemic effects were investigated in the diabetic rat model induced by streptozotocin (STZ). Treatments of rats with 200 mg/kg of the TRF-cor, TRF-cra (each, p.o.) or 20 mg/kg of Niga-$F_1$ significantly inhibited the increase of blood glucose concentration about 44.8%, 28.7% or 20.6%, respectively, in the diabetic rats. In addition, treatments with those fractions inhibited the increase of serum concentrations of triglyceride, total cholesterol or LDL-cholesterol caused by STZ. The inhibitory rate on atherogenic index (AI) values of the TRFcor (200 mg/kg), TRF-cra (200 mg/kg) or Niga-$F_1$ (20 mg/kg)-treated groups were decreased about 55.7%, 36.3% or 22.6%, respectively, comparable to STZ-treated group. In the oral glucose tolerance test, treatment of TRF-cor or TRF-cra inhibited the increase of blood glucose concentration in the STZ-induced rats. Administration of 20 mg/kg of Niga-$F_1$ (p.o.) also exhibited similar effects with the effects of both TRFs at 200 mg/kg dose (p.o.). These results support that the triterpenoids, in particular Niga-$F_1$, are contributed to the antidiabetic effects of R. coreanus or R. crataegifolius.

• Nutrition Research and Practice
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• v.7 no.4
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• pp.294-301
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• 2013

In this study, we examined the hepatic anti-steatosis activity of carnosic acid (CA), a phenolic compound of rosemary (Rosmarinus officinalis) leaves, as well as its possible mechanism of action, in a high-fat diet (HFD)-fed mice model. Mice were fed a HFD, or a HFD supplemented with 0.01% (w/w) CA or 0.02% (w/w) CA, for a period of 12 weeks, after which changes in body weight, blood lipid profiles, and fatty acid mechanism markers were evaluated. The 0.02% (w/w) CA diet resulted in a marked decline in steatosis grade, as well as in homeostasis model assessment of insulin resistance (HOMA-IR) index values, intraperitoneal glucose tolerance test (IGTT) results, body weight gain, liver weight, and blood lipid levels (P < 0.05). The expression level of hepatic lipogenic genes, such as sterol regulating element binding protein-1c (SREBP-1c), liver-fatty acid binding protein (L-FABP), stearoyl-CoA desaturase 1 (SCD1), and fatty acid synthase (FAS), was significantly lower in mice fed 0.01% (w/w) CA and 0.02% (w/w) CA diets than that in the HFD group; on the other hand, the expression level of ${\beta}$-oxidation-related genes, such as peroxisome proliferator-activated receptor ${\alpha}$ (PPAR-${\alpha}$), carnitine palmitoyltransferase 1 (CPT-1), and acyl-CoA oxidase (ACO), was higher in mice fed a 0.02% (w/w) CA diet, than that in the HFD group (P < 0.05). In addition, the hepatic content of palmitic acid (C16:0), palmitoleic acid (C16:1), and oleic acid (C18:1) was significantly lower in mice fed the 0.02% (w/w) CA diet than that in the HFD group (P < 0.05). These results suggest that orally administered CA suppressed HFD-induced hepatic steatosis and fatty liver-related metabolic disorders through decrease of de novo lipogenesis and fatty acid elongation and increase of fatty acid ${\beta}$-oxidation in mice.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.41 no.4
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• pp.50-58
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• 2018

Process Capability ($C_{pk}$) is a representative measure of how well the producer manages dispersion and bias for the specifications needed by the consumer. This is expressed as a ratio of 6 times the natural tolerance to the specification. As the producer manages the dispersion small, the capacity index becomes higher. And it is classified into 5 grades according to the degree of management. It is a measure of the quality of processes used in most industrial fields. However, $C_{pk}$ is calculated by only reflecting the mean and dispersion of the process, there is a disadvantage that it can not give information about the economic loss caused by the inconsistency of the process with the target value. Overcoming these drawbacks, process capability indexes reflecting various types of loss functions such as $C_{pm}$, $C^+_{pm}$ and $C_{pl}$ have been developed. However, all of these previous studies have applied the limit to the consumer specification, which is based on the traditional and passive quality perception that the quality characteristic should exist within the limits of the consumer specification. In this study, we will develop 'Customer Satisfaction Quality Indicator (CSQI)' which is a quantitative indicator that can be fully evaluated when the manufacturer's specification limit, which is an aggressive quality strategy, is applied. This is expected to be useful decision information for both producers and consumers.

• Journal of Korean Society of Forest Science
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• v.87 no.3
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• pp.404-414
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• 1998

The purpose of this study was to investigate the influence of air pollution using epiphytic lichens on forest trees around Ulsan and Onsan industrial complex from April to June, 1997. The distribution of lichens was investigated at 58 sampled sites. In this study, 16 kinds of epiphytic lichens were recorded, of them, Lepraria sp. having a tolerance to air pollution showed the highest frequency as 30.85%, and in order of Lecanora strobilina(26.18%) and Parmelia austrosinensis(13.42%) unknown to tolerance of air pollution. The number of lichens was gradually decreased around industrial complex, where so - called "lichen desert" was detected. As being distant from the industrial complex, the mean degrees of cover were increased. The degrees of cover in the investigated sites ranged from I to V. According to $SO_2$ concentration limiting lichen's growth, the pattern of distribution of Cladonia sp., Dirinaria applanata, Parmelia austrosinensis, Lepraia sp. and Lecanora strobilina were dissimilar by sensitivity to air pollution Especially Lepraria sp. and Lecanora strobilina were widely distributed to degree of cover from I to V, and as the both had a similar distribution pattern, it could be inferred that Lecanora strobilina had also a tolerance to air pollution. The IAP values ranging from 0 to 64.3 were arranged into six groups and the investigated area was delineated into six IAP zones to represent degree of air environment. It was a high IAP value as being distant from industrial complex. The mare IAP increased, the more number of kinds of lichens increased. It was confirmed that the number of species, coverage and IAP value of epiphytic lichens showed a tendency to decrease of urban area and industrial complex.

• Korean Journal of Ecology and Environment
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• v.51 no.1
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• pp.86-95
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• 2018

The objective of this study was to describe the development and testing of an initial ecological health assessment model, based on the index of biological integrity (IBI) using fish assemblages, before establishing the final and currently used model for ecological health assessment, conservation and management of freshwater fish in Korea. The initial fish IBI model was developed during 2004~2006 and included 10 metrics, and in 2007 the final IBI 8-metric model was established for application to streams and rivers in four major Korean watersheds. In this paper, we describe how we developed fish sampling methods, determined metric attributes and categorized tolerance guilds and trophic guilds during the development of the multi-metric model. Two of the initial metrics were removed and the initial evaluation categories were reduced from six to four (excellent, good, fair, poor) before establishing the final national fish model. In the development phase, IBI values were compared with chemical parameters (BOD and COD as indicators of organic matter pollution) and physical habitat parameters to identify differences in IBI model values between chemical and physical habitat conditions. These processes undertaken during the development of the IBI model may be helpful in understanding the modifications made and contribute to creating efficient conservation and management strategies for stream environments to be used by limnologists and fish ecologists as well as stream/watershed managers.

• Korean Journal of Ecology and Environment
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• v.45 no.3
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• pp.314-321
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• 2012

To quantitatively assess the effects of turbidity on egg development and larval fish survival, a laboratory fish rearing experiment was applied to different life stages (newly hatched larval stage, juvenile stage and pre-adult stage) of the Zacco platypus, one of the most universal and tolerant species in Korea. According to the stress index of turbidity in water with exposure time, three different treatments, including a reference condition (1~7 NTU) as well as intermediate (20~150 NTU) and high turbidity conditions (400~1,000 NTU) were applied, and egg hatching and larval fish mortality rates were observed. The mortality rates of newly hatched larval fish were significantly different among treatments (ANOVA, $F_{2,3}$=17.79, p<0.05). Average rates of survival to hatching were 20.9% (${\pm}0.1%$) for reference condition, 11% (${\pm}6.9%$) for intermediate level and 3.2% (${\pm}3.7%$) for high level conditions, respectively. A sudden change of mortality at the high level was observed within 5 days of the experiment. About 84% of juvenile fish survived until 20 experimental periods under conditions of reference turbidity, while survival under conditions of intermediate turbidity was over 80% of larval fish until day 13 of the experiment, but dropped to less than 10% after day 14 and 15 of two experiments. Fish mortality appeared from day 6 of the high turbidity experiment, and 50% mortality was achieved at day 9 to 10 of experiment. Full mortality occurred at day 14 of the experiment (RM-ANOVA, $F_{2,38}$, p<0.005). In the pre-adult stage experiment, no mortality was observed during the experiment at reference level treatment (20 days), while only slight mortality rates were observed for both intermediate and high levels until day 5 of the experiment, however, no further fish died in either experiment. It was significantly different compared to reference condition (RM-ANOVA, $F_{2,20}$=8.28, p<0.01), but no difference was observed between intermediate and high level conditions. Consequently, this tolerant species has been determined to be well adapted to high levels of turbidity in its adult stage, but more vulnerable throughout earlier life stages.

• Korean Journal of Food Science and Technology
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• v.43 no.2
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• pp.235-239
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• 2011

Liquid-state fermentation of Monascus koji was performed using 10% honey as the nutrient source. The rheological characteristics of flour doughs with added red koji broth were evaluated and revealed the following results. The falling number which represents the paste characteristics decreased, as the amount of added red koji broth increased. Adding 10% broth resulted in a falling number of $363{\pm}7.8s$ and with 20% it was $318{\pm}2.1s$. In the measurement of gelatinization using a rapid visco analyzer, increasing the red koji broth decreased peak viscosity, peak viscosity time, holding strength, final viscosity and set-back values, but initial pasting temperature and breakdown value increased. In the farinograph measurements, no significantly different absorption was found between the control and the treatments, and the results were 64.3-65.0%. The consistency and tolerance index of the doughs were higher in the treatments than the control. Increasing the broth addition ratio increased the measurement values, however development time and time to break down the doughs decreased. Stability also decreased and adding 20% broth resulted in a 9.3 min development time, and adding 40% broth resulted in a 3.0 min development time. In the alveographic analysis, the $P_{max}$ (overpressure) value of the control was 158.0 mm. $P_{max}$ value increased to 190.0 mm after adding 40% broth. However the values of L, G and W were higher in the control. As a result, little influence on dough rheology was observed by adding red koji broth 20%.

• Korean Journal of Environment and Ecology
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• v.33 no.2
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• pp.187-201
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• 2019

This study examined the physicochemical water quality and evaluated the ecological health in 14 sites of Geum River (upstream, mid-stream, and downstream) using the fish community distribution and guilds and eight multi-variable matrices of FAI (Fish Assessment Index) during June 2008-May 2009. The analysis of the water quality variables showed no significant variation in the upstream and mid-stream but a sharp variation due to the accumulation of organic matter from the point where the treated water of Gap and Miho streams flew. The analysis of physicochemical water properties showed that BOD, COD, TN, TP, Cond, and Chl-a tended to increase while DO decreased to cause eutrophication and algae development from the downstream where Miho and Gap stream merged. The analysis of fish community showed that the species richness index and species diversity index increased in the mid-stream area but decreased in the downstream area, indicating the stable ecosystem in the upper stream and the relatively unstable ecosystem in the downstream. The analysis of the species distribution showed that the dominant species were Zacco platypus that accounted for 20.9% of all fish species and Zacco koreanus that accounted for 13.1%. The analysis of the fish tolerance and feeding guild characteristics showed that the sensitive species, the insectivore species, and the aquatic species were dominant in the mid-stream point. On the other hand, contaminants from the sewage water treatment plant of Miho stream had a profound effect in the downstream to show the dominance of tolerant species, omnivorous species, and lentic species. Therefore, it is necessary to improve water quality by reducing the load of urban pollutants and to pay attention to the conservation and restoration of aquatic ecosystems.

• Korean Journal of Environmental Biology
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• v.34 no.4
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• pp.223-232
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• 2016

Drought is one of important environmental stress for plant. Drought has deleterious effect to plant growth including maize (Zea mays L.) such as vegetative and/or reproductive growth, root extension, photosynthesis efficiency, flowering, anthesis-silking interval (ASI), fertilization, and grain filling. In this study, we screened drought tolerant maize in 21 cultivars from different sources, sixteen NAM parent lines (B73, CML103, CML228, CML247, CML277, CML322, CML333, CML69, Ki11, Ki3, Ky21, M37W, Mo18w, NC350, Oh43 and Tx303), four Korean hybrids (Cheongdaok, Gangdaok, Kwangpyeongok and Pyeonganok) and one Southeast Asian genotype (DK9955). Drought stress (DS) index was evaluated with leaf rolling score at seedling stage and ASI at silking date. The leaf rolling scoring of CML228, DK9955 and Ki11 were determined 1.28, 1.85, 1.86, respectively. However, M37W, Kwangpyeongok, B73 and NC350 were determined over the 3. ASI analysis revealed that CML228, CML103, Cheongdaok, NC350, B73, CML322, Kwangpyeongok and Ki11 are represented less than 5 days under DS and less than 3 days of difference between DS and well-watered (WW), but CML69, Ki3, Pyeonganok, M37W, Mo18w and Gangdaok were represented more than 10 days under DS and more than 8 days of difference between DS and WW. Multi-Dimensional Scaling (MDS) analysis determined CML228, Ki11, and CML322 were regarded as drought tolerance cultivars. Eventually, Ki11 showed genetic similarity with Korean cultivars by QTL analysis and MDS analysis. Ki11 has a potential for development of drought tolerance maize with Korean cultivars.

• Culinary science and hospitality research
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• v.19 no.4
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• pp.119-135
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• 2013

This study investigates waxy barley powder substituted for wheat flour in bread recipes with the amounts of 0%(control), 5%, 10%, 15% and 20%. Waxy barley powder consisted of 8.33% of moisture content, 10.47% of crude protein, 1.63% of crude fat, and 2.97% of crude ash. Sedimentation value and pelshenke value have decreased as the waxy barley powder content increased. The farinograph measurement result of the bread made with waxy barley powder showed that consistency, water absorption, development time, stability and time breakdown have increased as the waxy barley powder content increased. The amylograph measurement result of the bread made with waxy barley powder showed that T have increased as the waxy barley powder content increased. Their P, H and P-H have decreased as the ingredient contents increased. Baking loss and specific loaf volume have decreased as the waxy barley powder content increased. The chromaticity measurement result of the bread made with waxy barley powder showed no significant difference as the waxy barley powder content increased. The texture measurement result showed that the hardness and gumminess of bread have increased as the waxy barley powder content increased. Their cohesiveness, springiness and chewiness have decreased as the ingredient contents increased. Overall preference scores showed a high acceptability for the bread made with 10% waxy barley powder.