• Journal of Aerospace System Engineering
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• v.6 no.3
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• pp.1-6
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• 2012

It is booming to use computer owing to the information society, and embedded software application have grown in airborne systems and equipment. So this introduces airborne software, RTCA DO-178B, life cycle and its data, and software development pitfalls in design and certification.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.23 no.6
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• pp.422-428
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• 2011

Optimal reliability indices were found by optimizing life cycle cost(LCC) of pier type quay walls. Failure probability of pier and shore bridge were calculated by response surface method. Then, they were used to obtain recovery cost after damage. Costs for initial construction and maintenance were also considered in finding optimal reliability indices. Target reliability indices which may be used in reliability based design were suggested by numerical examples under seismic load and ship load.

• Biomolecules & Therapeutics
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• v.20 no.2
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• pp.177-182
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• 2012

Tetrazolium violet is a tetrazolium salt and has been proposed as an antitumor agent. In this study, we reported for the first time that tetrazolium violet not only inhibited human lung cancer A549 cell proliferation but also induced apoptosis and blocked cell cycle progression in the G1 phase. The results showed that tetrazolium violet significantly decreased the viability of A549 cells at $5-15{\mu}M$. Tetrazolium violet -induced apoptosis in A549 cells was confirmed by H33258 staining assay. In A549, tetrazolium violet blocked the progression of the cell cycle at G1 phase by inducing p53 expression and further up-regulating p21/WAF1 expression. In addition, an enhancement in Fas/APO-1 and its two forms of ligands, membrane-bound Fas ligand (mFasL) and soluble Fas ligand (sFasL), as well as caspase, were responsible for the apoptotic effect induced by tetrazolium violet. The conclusion of this study is that tetrazolium violet induced p53 expression which caused cell cycle arrest and apoptosis. These findings suggest that tetrazolium violet has strong potential for development as an agent for treatment lung cancer.

• Journal of Information Technology Services
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• v.22 no.3
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• pp.65-83
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• 2023

Due to the development of modern technology and the enlargement of industrial scale, the scale of many projects is expanding and the complexity is also increasing. Individual management of existing projects cannot effectively manage projects in this trend, and it is necessary to systematically manage the entire process from initiation to completion. Accordingly, the need for integrated management and life cycle management that can efficiently manage the entire project is emerging, and for this, a systematic project management system is also required. PMS enables efficient project management by linking business processes such as resource, schedule, scope, and output management of a project with separately separated infrastructure accordingly. In this paper, a research model was proposed to manage the project from the perspective of implementing integrated management and life cycle management, especially during R&D project execution, and to prove the mediating role between PMS and R&D project performance for this purpose. The proposed research model will be able to help companies and organizations that feel the need to implement integrated management and life cycle management and are preparing to build a PMS-type system or that have already been established to efficiently perform project management.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.3
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• pp.240-247
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• 2021

As competition among companies has intensified and the life cycle of products has been shortened, strong innovation is needed to meet consumers' needs. In addition, it is necessary to shorten the life cycle of the product and reduce the time required for technology development for the competitive advantage of the product. In particular, venture companies where new technologies and ideas are important require more innovative capabilities than others companies. Therefore, this study analyzed the impact of technology innovation capabilities (product development process capability, human resource capability and financial capability) on sales by technology development for small and medium venture companies and analyzed moderating effect of technology development period on the relationship between technology innovation capabilities and sales by technology development. The data of 'Small and Medium Business Technology Statistics' collected by the government every year were used for analysis. Technology-intensive ventures were extracted from this data. In addition, the moderating effect was analyzed through hierarchical regression analysis. This study shows that product planning capability, test capability, and R&D expenditure have a positive impact on sales by technology development. In this study, the product development period showed a positive moderating effect on product development capability and sales performance. On the other hand, the product development period showed a negative moderating effect on R&D expenditure and sales by technology development.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.1282-1288
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• 2011

Recently, the demand regarding reliability and safety of the railroad are increased as built to high-speed railway and Driverless LRT systems. Accordingly, effective management of construction projects is being applied, with the introduction and use of PMIS computerized systems. Due to the construction of railways, from the start of PMIS research planning, design, procurement, to construction and commissioning, various expertise is being carefully gathered, and by integrating it into the unified budget ideas and processes, rational, efficient, organized, and manageable financial plans are developed for the computerized system. However, the current PMIS does not take into account the life-cycle. Therefore, this study is to bring attention to the BIM smart BOM-based configuration management for life-cycle through the consideration for railway construction project management.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2017.05a
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• pp.272-273
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• 2017

As businesses put a greater emphasis on outward appearances, the demand for external window cleaning has been on the rise. However, with the conventional labor-intensive window cleaning method, it is hard to meet this demand. Therefore, this study proposes a Life Cycle Cost (LCC) analysis model for a guiderail-type cleaning robot, and estimate the LCCs of the conventional method and the cleaning robot. The findings of this research are expected to serve as a guide for future development of a cleaning robot.

• Journal of the Korea Safety Management & Science
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• v.8 no.1
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• pp.113-130
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• 2006

As environmental damage increase by a highly developed material civilization of today, many companies take a growing immensely interest in the influence of environment for beginning a new paradigm year by year. The previous assessments dose not run the gamut of industry but is confined within a certain facility or an area. Industrial processes and operations can not be accomplished independently but are connected with each others through suppliers and customer, and these ideas are fundamental notions of Life Cycle Assessment(LCA). This paper will introduce Life Cycle Assessment(LCA) in environment which is rising, and would like to build environmental management system using approach of Quality Function Deployment(QFD) and Safety Function Deployment(SFD) belonging to the assessment method.

• Journal of the Korean housing association
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• v.15 no.1
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• pp.33-40
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• 2004

Considering the present development situation of rental apartment since 1982, the supply of rental housing for low-income dwellers has contributed a amount of quantities, but has been deficient qualities in housing policy. To propose the device of remodeling for low-income dwellers in deteriorated apartment, this study investigated the energy consumption of central heating system and the characteristics of maintenance cost in permanent rental apartment. The results of evaluation of alternative heating systems by Life Cycle Costing in permanent rental apartment were as follows; From Life Cycle 15∼20 years by Present Worth Method, the economic heating system of remodeling is central heating system (heat source: B-C oil), unit heating system(natural gas), central heating system(natural gas) in order.

• Proceedings of the Korean Society of Computer Information Conference
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• 2014.07a
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• pp.93-94
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• 2014

Enterprises or public organizations have invested in development of their information systems and operated them repeatedly. Since these information systems projects have unique characteristics such as technology sensitiveness, network effectiveness, embeddedness, and externality, these investment projects have been not taken care of in the field of administration and evaluation. And then, it is difficult to manage and monitor them. In this research, we propose a evaluation life cycle management model on the basis of result to evaluate information systems. This life cycle model with ten stages would furnish a guide to introduction of total evaluation systems.