• Title/Summary/Keyword: Development 2.0

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Callus Induction and Plant Regeneration Efficiency According to Tissue Culture Conditions in Teff grass (Eragrostis) (테프그라스 조직배양을 통한 캘러스 형성 및 식물체 재분화 효율)

  • Lee, Ki-Won;Moon, Jin Young;Park, Hyung Soo;Choi, Gi Jun;Kim, Ki-Yong;Ji, Hee Chung;Hwang, Tae Young;Lee, Sang-Hoon
    • Journal of Animal Environmental Science
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    • v.19 no.1
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    • pp.55-62
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    • 2013
  • Teff grass is a warm season C4 annual grass that is used for dry hay, silage and haylage. We have developed a high-frequency plant regeneration system for teff grass via callus culture using mature seeds. It was revealed that mature seeds cultured on MS medium supplemented with 2 mg/l 2,4-D, 0.5 g/L proline, 0.5 g/L casamino acid and 3 g/L Gelrite under light condition produced the highest percentage of callus formation (91.9%). Addition of cytokinins (BA) at 0.0~0.5 mg/L to media containing 2 mg/l 2,4-D enhanced callus growth. The most suitable medium for plant regeneration from dehydrated calli was MS agar medium supplemented with 0.1 mg/l NAA, 1 mg/l BA, 0.5 g/L proline, 0.5 g/L casamino acid 3 g/L Gelrite which induced the highest percentage of calli forming shoots (47.0%). The shoots were rooted at the highest rate (100%) when transferred onto 1/2 MS medium and acclimated in greenhouse conditions.

Development 2.0: Principles and Warnings for Leveraging Advances in Information Communication Technologies for Improved Development Efforts

  • Kang, Christina Soyeon;Lal, Bhavya
    • STI Policy Review
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    • v.1 no.3
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    • pp.25-37
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    • 2010
  • Advances in Information Communication Technologies (ICT) have demonstrated tremendous potential for solving development challenges and improving development processes, culminating in the new Development 2.0. Many development practitioners have embraced ICT (particularly on Web 2.0 and mobile phone technologies and applications), which have become hot topics in both the development community and the policy community as they engage in development practice and dialogue. Despite this excitement, there lacks among the policy community a robust understanding of the powers and pitfalls of ICT in development, executed actions to back the excited chatter, and dissemination of this understanding to practitioners and policymakers alike. We conducted a literature review, interviewed experts, and engaged in discussion with leaders in international development and science and technology policy to provide an operational framework base in which to view ICT in development. This framework regards ICT as tools that support more effective and efficient community development actions and appropriate consideration of general guidelines, which enable better engagement across and within sectors and individuals. Flexibility and accountability are critical requirements pervading throughout the various actions and guidelines, which promote transparent, partnership-based, and sustainable development. We highlight the strengths and weaknesses of ICT to focus on the cautions to keep ICT access and distribution in context, understand the various levels of technologies and services, and dig below the surface as excitement about ICT increases and threatens to become a short-term solution. We offer ideas for specific programs that policymakers can implement to contribute to a more efficient and effective development process to ultimately support global human development, but stress the endless possibilities that can be explored with creativity and flexibility beyond what is proposed here.

Properties and Fabrication of 5Cu0.6Fe0.4-Al2O3 Composite by High Frequency Induction Heated Sintering (고주파유도가열 소결에 의한 5Cu0.6Fe0.4-Al2O3 복합재료제조 및 기계적 성질)

  • Lee, Dong-Mok;Song, Jun-Young;Park, Na-Ra;Shon, In-Jin
    • Korean Journal of Metals and Materials
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    • v.47 no.11
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    • pp.754-758
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    • 2009
  • Dense $5Cu_{0.6}Fe_{0.4}-Al_{2}O_{3}$ composite was consolidated from mechanically synthesized powders by high frequency induction heating method within 2 min. Consolidation was accomplished under the combined effects of a induced current and mechanical pressure. Dense $5Cu_{0.6}Fe_{0.4}-Al_{2}O_{3}$ with relative density of up to 95% was produced under simultaneous application of a 80 MPa pressure and the pulsed current. Fracture toughness and hardness of the composite are $7.6MPa{\cdot}m^{1/2}$ and $844kg/mm^{2}$ respectively.

Protective Effect of Combinational Antidotes Composed of Physostigmine and Procyclidine Against Nerve-agent Poisoning

  • Kim, Yun-Bae;Cheon, Ki-Cheol;Hur, Gyeung-Haeng;Phi, Taek-San;Kim, Jee-Cheon;Deasik Hang
    • Toxicological Research
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    • v.16 no.3
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    • pp.195-200
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    • 2000
  • Antidotal efficacy of physostigmine plus procyclidine, the combinational prophylactics for organophosphate poisoning, was evaluated in rats and guinea pigs. To assess the dose-response relation-ship in rats, various doses (0.3-6.0mg/kg) of procyclidine in combination with a fixed dose (0.1mg/kg) of physostigmine were pretreated subcutaneously 30 min prior to subcutaneous exposure to nerve-agents. Physostigmine alone exerted protection ratios of 2.44, 1.20, 1.50, 1.50 and 2.20 folds for tabun, sarin, soman, cyclosarin and V-agent, respectively. Interestingly, coadmnistration of procyclidine with physostigmine exhibited remarkable synergistic effects in a dose-dependent manner, leading to 4.00~8.00 folds for tabun, 2.15-8.50 folds for sarin, 1.92~507 folds for so man, 2.15~2.90 folds for cyclosarin, and 2.71~10.50 folds for V-agent. On the contrary, a low effect (l.65 fold) was achieved with the traditional antidotes atropine (17.4 mg/kg) plus 2-pralidoxime (30 mg/kg) treated immediately after soman poisoning. Noteworthy, the combinational prophylactics markedly potentiated the effect of atropine plus 2-pralidoxime to 6.13 and 12.27 folds with 1.0 and 3.0 mg/kg of procyclidine, respectively, against soman poisoning. In guinea pigs, the physostigmine plus procyclidine prophylactics exerted protective effects of 3.00~4.70 folds against soman intoxcation, which were much higher at low doses (0.3~1.0 mg/kg) of procyclidine than those in rats. Taken together, it is proposed that the combinational prophylactics composed oj physostigmine and procyclidine could be a promising antidote regimen for the poisoning with organophosphates possessing diverse properties.

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A Study on Comparison of Development Productivity of Spring 2.5 and Seam 2.0 Based JPetStore Order System (JPetStore 주문시스템 기반으로 Spring 2.5와 Seam2.0의 개발 생산성 비교 연구)

  • Lee, Myeong-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.7
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    • pp.2610-2615
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    • 2010
  • This paper proposes an object-oriented software development guidance and an evaluation index for the productivity related to Spring 2.5 and Seam 2.0 framework. Lightweight container architecture, such as the EJB, but not heavy, to provide all of the architecture is possible. Currently in production until the lightweight container architecture, known most commonly used architecture framework is Spring and Seam. However, there is no comparison research about the performance of Spring 2.5 and Seam 2.0 framework with same identical platform. In this study, the Java Pet Store blueprint application development platform environment based on the same ordering system JPetStore Spring 2.5 and Seam 2.0 is in the design and implementation. In addition, comparison and standardization of software development productivity assessment is to provide guidance.

Ligand Based CoMFA, CoMSIA and HQSAR Analysis of CCR5 Antagonists

  • Gadhe, Changdev G.;Lee, Sung-Haeng;Madhavan, Thirumurthy;Kothandan, Gugan;Choi, Du-Bok;Cho, Seung-Joo
    • Bulletin of the Korean Chemical Society
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    • v.31 no.10
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    • pp.2761-2770
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    • 2010
  • In this study, we have developed QSAR models for a series of 38 piperidine-4-carboxamide CCR5 antagonists using CoMFA, CoMSIA and HQSAR methods. Developed models showed good statistics in terms of $q^2$ and $r^2$ values. Best predictions obtained with standard CoMFA model ($r^2$ = 0.888, $q^2$ = 0.651) and combined CoMSIA model ($r^2$ = 0.892, $q^2$ = 0.665) with electrostatics and H-bond acceptor parameter. The validity of developed models was assessed by test set of 9 compounds, which showed good predictive correlation coefficient for CoMFA (0.804) and CoMSIA (0.844). Bootstrapped analysis showed statistically significant and robust CoMFA (0.968) and CoMSIA (0.936) models. Best HQSAR model was obtained with a $q^2$ of 0.662 and $r^2$ of 0.936 using atom, connection, hydrogen, donor and acceptor as parameters and fragment size (7-10) with optimum number of 6 components. Predictive power of developed HQSAR model was proved by test set and it was found to be 0.728.

A Roentgenographic Study on the Development of Roots of Mandibular Permanent Posterior Teeth (하악영구구치 치근발육에 관한 방사선학적 연구)

  • 고명연;정성창
    • Journal of Oral Medicine and Pain
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    • v.6 no.1
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    • pp.23-34
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    • 1981
  • In order to evaluate the correlation of age with development stage on permanent lower posterior teeth. the author exmined the roentgeregrams in standard films taken by intraoral technic and analysed the development phases of 1358 teeth of 500 males ranging from 9 to 15 years. The development was divided into 7 phases : Crown complete (Cr. C.). Root length 1/4(R. 1/4) Root length /2 (R. 1/2) Apical closure complete (A.C) The obtained results were as follows : 1. The formation of roots in full length on posterior teeth was complete as follow : a. Roots of 1st premolar : 12.72 years b. Roots of 2nd premolar : 12.94 years c. Meral Roots of 2nd molar : 13.38 years d. Distal Roots of 2nd molar : 13.46 years 2. The formation of apical forman of premolar was closured as follows : a. Apical foramen of root of 1st premolar : 13.64 years b. Apical foramen of root of 2nd premolar : 13.93 years 3. As a general rule. the mesial roots of second molar were developed earlier than distal roots of second molar. 4. In the correlation of age with the development stage, the regression equations. the correlation coefficents. and the sample numbers were “Y = 0.8370x + 10.2160, r = 0.71(p<0.01), n = 318”on lower first premolar, “Y = 0.6984x + 10.2148, r = 0.71(p<0.01), n = 385”on lower second premolar, “Y = 0.8810x + 10.2040, r = 0.65(p<0.01), n = 344”on mesial Root of lower second molar, and “Y = 0.7310x + 10.7940, r = 0.66(p<0.01), n = 311”on Distal Root of lower second molar respectively.

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Effect of Curing Additives on Color Property of Smoked Duck Meat (염지제가 훈연오리의 육색 특성에 미치는 영향)

  • Kang, Geunho;Cho, Soohyun;Seong, Pil-Nam;Park, Kyoungmi;Kang, Sun Mun;Park, Beom-Young
    • Korean Journal of Poultry Science
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    • v.40 no.3
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    • pp.179-185
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    • 2013
  • This study was conducted to investigate the effect of curing additives on color property of smoked duck meat. Curing process of samples was performed one of the following treatments: C, non-curing: T1, 2.43% salt: T2, 2.43% salt + 0.49% tripolyphosphate (TPP): T3, 2.43% salt + 0.49% TPP + 0.002% nitrite: T4, 4.76% duck seasoning: and T5, 1.47% salt + 0.24% TPP + 0.2% L-ascorbic acid. Instrumental meat color of both breast and thigh of smoked duck showed that the CIE $a^*$ value of the T4 was significantly (p<0.05) higher than that of the other treatments, whereas T5 had a significantly (p<0.05) higher CIE $b^*$ value than the other treatments. In results of nitroso pigment, T5 of smoked duck breast was significantly (p<0.05) higher value compared to other treatments, whereas T3 and T5 of smoked duck thigh had a significantly (p<0.05) higher value than other treatments. Heme pigment contents of control and T5 was significantly (p<0.05) higher value compared to other treatments in smoked duck breast. Meat color of T3 by sensory evaluation showed redder (p<0.05) than other treatments. These results suggested that using L-ascorbic acid is revealed to be pink color without nitrite or pigment when manufacturing of smoked duck meat.

A Longitudinal Study on Farm Householder's Perception of Economic Problem (전업${\cdot}$겸업 농가의 가정 내 경제문제 인지의 변화)

  • Cho, Young-Sook;Lee, Duk-Jae;Hwang, Dae-Yong;Park, Eun-Shik;Ko, Jeong-Sook
    • Journal of Agricultural Extension & Community Development
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    • v.13 no.2
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    • pp.265-276
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    • 2006
  • This study focused on the trends in recognising an economic concern as the most difficult problem in the farm household that was categorised as a full-time farm household or a part-time household according to income structure from agricultural activity. Log-linear models were suggested to compare the change of recognising an economic problem between year 2003 and 2005. As a result, there was no significant difference in recognising an economic problem between full-time farm household and part-time farm household both in 2003 ($x^2$=0.04;p=0.84) and in 2005 ($x^2$=1.08; p=0.30). It was revealed, however, that full-time farm household had increasingly recognised an economic problem over years. Log-linear models showed that full-time farm households tended to recognise the economic problem 1.11 times as much as part-time farm households in 2005, compared to 0.97 times in 2003.

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Quantitation and Radical Scavenging Activity Evaluation of Iridoids and Phenylethanoids from the Roots of Phlomis umbrosa (Turcz.) using DPPH Free Radical and DPPH-HPLC Methods, and their Cytotoxicity

  • Le, Duc Dat;Nguyen, Duc Hung;Zhao, Bing Tian;Min, Byung Sun;Song, Si Whan;Woo, Mi Hee
    • Natural Product Sciences
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    • v.25 no.2
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    • pp.122-129
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    • 2019
  • The roots of Phlomis umbrosa (Turcz.) (Phlomidis Radix) have been traditionally used to treat cold, reduce swelling and staunch bleeding. Four iridoids (1 - 3 and 5) and six phenylethanoid derivatives (4, and 6 - 10) were isolated from the roots of P. umbrosa. A simple, sensitive, and reliable analytical HPLC/PDA method was developed, validated, and applied to determine 10 marker compounds in Phlomidis Radix. Furthermore, the isolates were evaluated for cytotoxic and anti-oxidant activities as well as DPPH-HPLC method. Among them, compounds 4 and 6 - 9 displayed potent anti-oxidant capacities using DPPH assay with $IC_{50}$ values of $27.7{\pm}2.4$, $10.2{\pm}1.1$, $18.0{\pm}0.8$, $19.1{\pm}0.3$, and $19.9{\pm}0.6{\mu}M$, and compounds 6, 8, and 9 displayed significant cytotoxic activity against HL-60 with $IC_{50}$ values of $35.4{\pm}3.1$, $18.6{\pm}2.0$, and $42.9{\pm}3.0{\mu}M$, respectively.