• Title/Summary/Keyword: Developing Asia

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Antiaging and Whitening Activities of Ethanol Extract of Yuza (Citrus junos SIEB ex TANAKA) By-product (유자 부산물 에탄올 추출물의 항노화 및 미백효과)

  • Kim, Da-Sel;Kim, Dong-Hyun;Oh, Myoung-Jin;Lee, Kwang-Geun;Kook, Moo-Chang;Park, Chang-Seo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.36 no.2
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    • pp.137-143
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    • 2010
  • Yuza (Citrus junos Sieb ex TANAKA) is a citrus fruit that is cultivated in northeast Asia. Citron is known for containing abundant antioxidants such as vitamin C, flavonoids, for example hesperidin and hesperetin, and terpenoids such as limononin. When mature citron is processed for tea or other beverage food products in Korea, massive amounts of seeds and pericarp are remained as waste. This study aimed to exploit the processed remnant of Citron for developing functional cosmetic applications. Ethanol extracts of Yuza seed and pericarp did not show significant radical scavenging activities measured by DPPH (2,2-diphenyl-1-picrylhydrazyl) method. But they contained significantly high phenolic compounds. Cultured human dermal fibroblasts and HaCaT keratinocytes were irradiated with 25 mJ UVB and the citron extracts were added to the medium of each culture. Cellular damages caused by UVB irradiation were prevented by the addition of the Yuza extract. In addition, the reduction of the enhanced MMP-1 expression after irradiation of UVB in human dermal fibroblasts was observed. Also the increased level of pro-inflammtory TNF-$\alpha$ in the UVB irradiated HaCaT cells was decreased. The collagen expression was enhanced by the extract. Yuza extract markedly inhibited melanin production from $\alpha$-MSH treated B16F1 melanoma cells. Melanin assay, tyrosinase zymography results indicated that Yuza extract had strong depigmenting activity. In conclusion, Yuza ethanol extracts have good anti-photoaging and strong anti-melanogenic efficacies.

An Empirical Investigation into the Role of Core-Competency Orientation and IT Outsourcing Process Management Capability (핵심역량 지향성과 프로세스 관리역량이 IT 아웃소싱 성과에 미치는 연구)

  • Kim, Yong-Jin;Nam, Ki-Chan;Song, Jae-Ki;Koo, Chul-Mo
    • Asia pacific journal of information systems
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    • v.17 no.3
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    • pp.131-146
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    • 2007
  • Recently, the role of IT service providers has been enlarged from managing a single function or system to reconstructing entire information management processes in new ways to contribute to shareholder value across the enterprise. This movement toward extensive and complex outsourcing agreements has been driven by the assumption that outsourcing information technology functions is a reliable approach to maximizing resource productivity. Hiring external IT service providers to manage part or all of its information-related services helps a firm focus on its core business and provides better services to its clients, thus obtaining sustainable competitive advantage. This practice of focusing on the strategic aspect of outsourcing is referred to as strategic sourcing where the focus is capability sourcing, not procurement. Given the importance of the strategic outsourcing, however, to our knowledge, there is little empirical research on the relationship between the strategic outsourcing orientation and outsourcing performance. Moreover, there is little research on the factor that makes the strategic outsourcing effective. This study is designed to investigate the relationship between strategic IT outsourcing orientation and IT outsourcing performance and the process through which strategic IT outsourcing orientation influences outsourcing performance, Based on the framework of strategic orientation-performance and core competence based management, this study first identifies core competency orientation as a proper strategic orientation pertinent to IT outsourcing and IT outsourcing process management capability as the mediator to affect IT outsourcing performance. The proposed research model is then tested with a sample of 200 firms. The findings of this study may contribute to the literature in two ways. First, it draws on the strategic orientation - performance framework in developing its research model so that it can provide a new perspective to the well studied phenomena. This perspective allows practitioners and researchers to look at outsourcing from an angle that emphasizes the strategic decision making to outsource its IT functions. Second, by separating the concept of strategic orientation and outsourcing process management capability, this study provides practices with insight into how the strategic orientation can work effectively to achieve an expected result. In addition, the current study provides a basis for future studies that examine the factors affecting IT outsourcing performance with more controllable factors such as IT outsourcing process management capability rather than external hard-to-control factors including trust and relationship management. This study investigates the major factors that determine IT outsourcing success. Based on strategic orientation and core competency theories, we develop the proposed research model to investigate the relationship between core competency orientation and IT outsourcing performance and the mediating role of IT outsourcing process management capability on IT outsourcing performance. The model consists of two independent variables (core-competency-orientation and IT outsourcing process management capability), and two dependent variables (outsourced task complexity and IT outsourcing performance). Comprehensive data collection was conducted through an outsourcing association. The survey data were analyzed using a structural analysis method. IT outsourcing process management capability was found to mediate the effect of core competency orientation on both outsourced task complexity and IT outsourcing performance. Further analysis and findings are discussed.

Entrepreneurs' Competencies and Business Performance: A Meta-Analysis (창업가의 역량이 기업성과에 미치는 영향에 대한 메타분석)

  • Lee, Hye Young;Kim, Jin Soo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.14 no.5
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    • pp.13-24
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    • 2019
  • The purpose of this study is to provide a theoretical basis for future studies by systematically integrating existing empirical studies that examine the relationship between the entrepreneurs' competencies and business performance. As the results of empirical studies examining the relationship between the entrepreneurs' competencies and business performance are mixed, this study tries to derive different results from individual studies through meta-analysis into standardized statistics(effect sizes). To accomplish the purpose, this study developed hypotheses about the positive effects of the entrepreneurial competencies including opportunity recognition competency, managerial competency, technical-functional competency, strategic competency, and relationship competencies on the business performance through theoretical reviews of the literature. Also, this study conducted meta-analysis with 15 sample data using open source based statistical program 'R'. The results of this study are as follows. The opportunity recognition competency, managerial competency, technical-functional competency, strategic competency, and relationship competency were found to significantly affect financial business performance. Also, each of the factors had a moderate effect size on the performance. Among these competencies, the most effective factor was the strategic competency, followed by the opportunity recognition competency, technical-functional competency, and relationship competency. There is still no study using meta-analysis on the relationship between the entrepreneurs' competencies and business performance in South Korea. Therefore, the results of this study are expected to provide implications for developing the theoretical basis of future studies.

The Prospect of the Development of Sea&Air Transportation Routes around the Yellow Sea Regions (환황해권 Sea&Air 수송의 발전 가능성 전망)

  • Kim, Tae-Seung;Won, Dong-Woo;Yun, Jung-Won
    • Journal of Korea Port Economic Association
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    • v.22 no.3
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    • pp.189-207
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    • 2006
  • As the development of Northeast Asian logistics hub becomes one of the national agenda for further development, the sea&Air transport around the Yellow Sea regions has drawn attention of many scholars and government officials. The Sea&air transport is a mode of transportation combining the advantage of high-speed in air transport with the advantage of low-price in sea transport. Hence the sea&air aims at a niche market between air and sea. This paper reviews the possibility of development of the sea&air transport in the aspects of competitiveness over other modes, future demand condition, and the change of the technology and transport environment. The result is that the sea&air is competitive in the aspect of time as well as cost, and sustainable in the aspect of future demand condition. But, it is not stable in the aspect of the conditions of technology or transport demand. Especially, the progress of air transport technology which is aiming at the door-to-door transport among mid- and small- cities, and the rapidly increasing strategic alliances of international airlines with Chinese airlines for the market of China will undermine the stability of the sea&air transport seriously As alternatives, this paper proposes the 3-stage development strategy of sea&air transport. First, at the stage of transshipement, the development of high speed vessels to reduce the time crossing the Yellow Sea and the proactive marketing strategy to induce Chinese-owned products should be emphasized. Second, the value added logistics activity which will secure the demand of the sea&air transport should be developed. Third, demand creation by developing the SCM hub in Incheon is final goal for the logistics hub strategy as well as the sea&air transport.

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Inhibitory Effects of Ethanol Extract from Angelica tenuissima Root on Oxidative Stress and Melanogenesis

  • Koo, Hyun Jung;Lee, Sung Ryul;Park, Yuna;Lee, Jin Woo;So, Gyeongseop;Kim, Sung Hyeok;Ha, Chang Woo;Lee, Sang Eun;Bak, Jong Phil;Ham, Su Ryeon;Lim, Hyosun;Kim, Youn Kyu;Sohn, Eun-Hwa
    • Korean Journal of Plant Resources
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    • v.31 no.4
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    • pp.312-321
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    • 2018
  • Angelica tenuissima, also known as Ligusticum tenuissimum, is classified as a food-related plant and has been used as traditional medicines treating headache and anemia in Asia. However, its anti-melanogenic effect has not been reported in detail. When the extract of Angelica tenuissima (ATE) was prepared by the extraction with 70% EtOH at $80^{\circ}C$ (final yield = 22%), the contents of decursin and Z-ligustilide in ATE were determined 0.06% and 8.43%, respectively. Total flavonoid and phenolic content in mg ATE were $5.52{\pm}0.07{\mu}g$ quercetin equivalents and $237.27{\pm}13.24{\mu}g$ gallic acid equivalents, respectively. Antioxidant capacity of ATE determined by DPPH and ABTS assay was increased with a dose dependent manner up to $1000{\mu}g/m{\ell}$. The amount of melanin synthesis followed by ${\alpha}-melanocyte$ stimulating hormone on B16F10 cells were significantly reduced in the presence of ATE (250 to $1000{\mu}g/m{\ell}$, p<0.05). ATE (125 to $1000{\mu}g/m{\ell}$, p<0.05) suppressed the tyrosinase activity but did not show any significant effect on ${\alpha}-glucosidase$ activity at the same condition. Taken together, ATE possesses tyrosinase inhibitory potential with significant antioxidant capacities. These effects of ATE might be involved in suppression of melanin synthesis, at least, in B16F10 cells. The anti-melanogenic potential of ATE will provide an insight into developing a new skin whitening product.

Development of New Strains of Wolfiporia cocos for Sclerotium Formation by 2-Way Cross-Breeding (이원교배에 의해 균핵 형성하는 복령 균주 개발)

  • Ka, Kang-Hyeon;Kim, Suyeon;Park, Mi-Jeong;Jeong, Yeun Sug;Ryoo, Rhim;Jang, Yeongseon;Choi, Jong-Woon;Kim, Seong Hwan
    • The Korean Journal of Mycology
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    • v.49 no.3
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    • pp.405-412
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    • 2021
  • Wolfiporia cocos is an important medicinal fungus that has been used in regions of Northeast Asia including Korea, Japan, and China. W. cocos is classified in Korea into two types (red bokryeong and white bokryeong) based on the internal colors (yellow orange-pale pink and white) of the sclerotium. Generally, the W. cocos type cultivated on farms produces white sclerotium. In this study, we endeavored to select strains that form sclerotium in sawdust medium using 2-way cross-breeding among two cultivated strains and three wild strains. Monospores were isolated from the fruiting bodies of cultivated and wild strains on potato dextrose agar. Thirty-nine strains of 338 hybrid strains isolated formed sclerotia with white or yellow colors upon culture for 3 months in Pinus densiflora sawdust medium. Selection for sclerotium forming strains using sawdust culture follows a very simple and easy procedure that is presented for the first time in this paper. We plan to test selected strains in the field to aid in developing new varieties for the future.

Determinants of New Product Performance and Environmental Dynamics as a Moderating Effect (신제품개발성과의 결정요인과 환경동태성의 조절효과)

  • Liu, Zhen;Bang, Ho-Yeol
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.1
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    • pp.845-858
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    • 2019
  • The most serious problem company facing in today's business environment is the failure of new product development outcomes. Statistically, almost half of the new products released each year failed. Despite the innovative technological advances, consumers' expectation level become much higher and global competition is intensifying. In addition, the new product life cycle is becoming shorter and shorter. It is difficult for a company to survive without developing long-lived products. The most important issue in a company's success and failure is the successful development and introduction of new products. Previous research has presented many determinants to achieve a successful new product development. This study focuses on dynamic competence as an important determinant, and identifies the constituting elements. Enterprises need to acquire, absorb, integrate and reconfigure their resources to survive and develop continuously. It is necessary to hold a dynamic ability switching resource bases in order to adapt to changing environments. The results of this study are as follows: First, the effect of learning, reconfiguration, and alliance capabilities on the new product development of small and medium-sized manufacturing enterprises seems to be positive. Second, the integrative and reconfiguration capabilities positively affect a new product development under high environmental turbulence.

A Study on the Design of Mathematics Education Program for Foreign Students Majoring in Natural Science and Engineering at University in Korea (이공계 대학 유학생을 위한 수학교육 프로그램 설계 및 적용)

  • Kim, Soocheol
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.5
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    • pp.147-157
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    • 2019
  • In this study, mathematics education program was developed for the foreign students who entered the science and engineering college of Korea in order to improve their basic competency and to prevent dropouts. It is applied to 5 Chinese students, 4 male students and 1 female student. Three students are majoring in engineering college and two students are majoring in natural science college. Before applying the mathematics education program to foreign students, most students did not draw a graph of the 'irrational function' and the 'exponential function' and did not understand the concept of the 'limit' at all. However, after applying the mathematics program, all foreign students were able to draw graphs of the various function and the limit values were calculated accurately. Through the results of this study, the researcher proposes some of the following. When developing mathematics education programs for foreign students, it is very important to develop teaching materials suitable for their level. Textbook developers need to select and organize contents that are essential for learning in university mathematics and to present mathematical concepts and examples considering the Korean language level of foreign students. Moreover, it will be necessary to try to present mathematical terms commonly used in Korea in their native language or English.

Anti-obesity and Anti-diabetic Effects of the Fermented Ethanol Extracts from White Jelly Fungus (Tremella fuciformis Berk) with Lactobacillus rhamnosus BHN-LAB 76 (Lactobacillus rhamnosus BHN-LAB 76로 발효한 흰목이버섯 (Tremella fuciformis Berk) 추출물의 항비만 및 항당뇨 효과)

  • Yoon, Yeo-Cho;Kim, Byung-Hyuk;Kim, Jung-Gyu;Lee, Jun-Hyeong;Park, YeEun;Park, Hye-Suk;Hwang, Hak-Soo;Kwon, Gi-Seok;Lee, Jung-Bok
    • Microbiology and Biotechnology Letters
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    • v.47 no.3
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    • pp.323-331
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    • 2019
  • White jelly fungus (Tremella fuciformis Berk; TF) has been used as a traditional medicine in Asia; it is known to prevent hypertension, aging, cancer, and arteriosclerosis. This study aimed to investigate the anti-diabetic effects of fermented Tremella fuciformis Berk (FTF) ethanol extracts fermented with L. rhamnosus BHN-LAB 76. We show that FTF increases the ${\alpha}$-glucosidase inhibitory activity and suppress the adipogenesis of 3T3-L1 adipocytes. These inhibitory effects of FTF are accompanied by the regulation of the phosphorylation of AMPK, JNK, and Akt. These data demonstrate that FTF not only inhibits adipogenesis by affecting the adipogenic signaling, but also increases the anti-diabetic effects by regulating the insulin signaling pathway. Therefore, we suggest that the FTF can be used for developing functional food and cosmetics materials.

Antioxidant and α-Glucosidase Inhibition Activity of Solvent Fractions from Prunus mume Ethanol Extract (매실 순차분획물의 용매별 항산화 활성 및 α-glucosidase 억제 효과)

  • Kim, Jeong-Ho;Cho, Hyun-Dong;Won, Yeong-Seon;Park, Wool-Lim;Min, Hye-Ji;Han, Sim-Hee;Moon, Kwang-Deog;Seo, Kwon-Il
    • Journal of Life Science
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    • v.29 no.10
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    • pp.1111-1119
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    • 2019
  • Prunus mume, known as maesil in Korea, has been widely cultivated in East Asia and used as medication and food. However, because most of the previous studies concerning P. mume had been investigated its under extract state, detailed studies are still required for its extensive utilization. In this study, we evaluated the antioxidant and ${\alpha}-glucosidase$ inhibitory activities of solvent fractions of P. mume ethanol extracts. The ethyl acetate fraction showed higher DPPH radical scavenging activity, ABTS radical scavenging activity, reducing power, and hydrogen peroxide scavenging activity than other fractions. The DPPH radical scavenging activities of ethyl acetate fraction was 67.79%; ABTS radical scavenging activity was 60.03%; reducing power ($OD_{670}$) was 1.26; and hydrogen peroxide scavenging activity was 93.18% at $500{\mu}g/ml$. Also, the ethyl acetate and methanol fraction showed effective levels of ${\alpha}-glucosidase$ inhibition activity (69.25% and 72.29% at $500{\mu}g/ml$). Total polyphenol contents and total flavonoid contents of the ethyl acetate fraction were 88.28 mg/g (gallic acid equivalent) and 70.38 mg/g (quercetin equivalent), respectively. These results suggest that the physiological activities of the ethyl acetate fraction are associated with its polyphenol and flavonoid contents. Therefore, this study can be used as basic data for developing natural antioxidants and potential functional material using P. mume.