• The Korean Journal of Physiology and Pharmacology
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• v.1 no.5
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• pp.591-595
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• 1997

An ex vivo assay determining the flavin-containing monooxygenase (FMO) activity in perfused rat liver has been developed by assessing the rate of thiobenzamide S-oxide (TBSO) formation from the infused thiobenzamide (TB). The hepatotoxicity by TB or TBSO was not a critical factor for maintaining the FMO activity for up to 50 min. The FMO activity expressed in nmoles TBSO produced/g liver/min was the same for the recycling and non-recycling perfusion. This implies that reduction of the oxidized TBSO back to the parent compound (TB) is negligible. Hydrolysis of the collected perfusates with either ${\beta}-glucuronidase$ or arylsulfatase did not increase the TBSO level and thus, TBSO does not appear to undergo conjugation either to glucuronide or sulfate esters. Thus, measuring the rate of TB S-oxidation in the isolated perfused liver with 1 mM TB for 50 min provides a useful tool for evaluation of the hepatic FMO activity in the absence of hepatic necrosis and without the interferences caused by further conjugation or back reduction of the TBSO to the parent TB.

• Korean Journal of Veterinary Research
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• v.48 no.3
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• pp.357-361
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• 2008

Although power analysis is of important tool of research, investigators in veterinary medicine are unaware of the concepts of the statistical power. Two types of error occur in classical hypothesis testing and, those errors should be avoided, if possible. Since power is highly dependent on the sample size, whenever declaring non-statistically significant result they should consider the potential for committing a Type II error in their studies, which refers to the probability of falsely stating that two treatments are equivalent despite true difference between them. Also, sample size determination is one of the most important tasks facing the researcher when planning a diagnostic study, and provides valuable information on the characteristics of a test performance. This type of analysis forms the basis for proper interpretation of test results. The aim of this article was to re-evaluate some selected studies on diagnostic test reported in the domestic veterinary publications to determine the power and necessary sample size for inequality testing to ensure the desired power. Power calculations were illustrated using real-life examples of comparison of a new test and a reference test for detecting antibodies of various animal diseases. Factors affecting to the power were also discussed.

• Journal of Institute of Control, Robotics and Systems
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• v.12 no.2
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• pp.119-129
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• 2006

Art psychotherapy is widely accepted as an effective tool for diagnosis and treatment of psychological disorders. Important factors for art psychotherapy diagnosis, based on the projection theory that the world of the inner mind appears in drawings, include main color and imbalance of a drawing. This paper develops a system for a machine to determine the main color and the imbalance of a drawing by color recognition and edge detection. Our proposed color recognition procedure adopts NBS(National Bureau of Standards) distance between colors in HVC(Hue, Value, Chroma) color space which is most similar to the human eye's color perception. Our edge detection procedure applies blurring, clustering and transformation to a standard color in a series. Our system considers the numbers of pixels and clusters for each color as a criterion for main color and the frequency of edge coordinates for each region for imbalance. The proposed machine procedure, verified through case studies, can help overcome the subjectivity, ambiguity and uncertainty in human decision involved in art psychotherapy.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2000.11a
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• pp.295-298
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• 2000

In this research, a novel sampling strategy for a CMM to inspect freeform surfaces is proposed. Unlike primitive surfaces, it is not easy to determine the number of sampling points and their locations for inspecting freeform surfaces. Since a CMM operates with slower speed in measurement than optical measuring devices, it is important to optimize the number and the locations of sampling points in the inspection process. When a complete inspection of a surface is required, it becomes more critical. Among various factors to cause shape errors of a final product, curvature characteristic is essential due to its effect such as stair-step errors in rapid prototyping and interpolation errors in NC tool paths generation. Shape errors are defined in terms of the average and standard deviation of differences between an original model and a produced part. Proposed algorithms determine the locations of sampling points by analyzing curvature distribution of a given surface. Based on the curvature distribution, a surface area is divided into several sub-areas. In each sub-area, sampling points are located as further as possible. The optimal number of sub-areas. In each sub-area, sampling points are located as further as possible. The optimal number os sub-areas is determined by estimating the average of curvatures. Finally, the proposed method is applied to several surfaces that have shape errors for verification.

• Structural Engineering and Mechanics
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• v.18 no.5
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• pp.591-607
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• 2004

The substance of the use of the derived non-linear creep constitutive equations under variable stress levels (see first part of the paper, Kmet 2004) is explained and the strategy of their application is outlined using the results of one-step creep tests of the steel spiral strand rope as an example. In order to investigate the creep strain increments of cables an experimental set-up was originally designed and a series of tests were carried out. Attention is turned to the individual main steps in the production and application procedure, i.e., to the one-step creep tests, definition of loading history, determination of the kernel functions, selection and definition of constitutive equation and to the comparison of the resulting values considering the product and the additive forms of the approximation of the kernel functions. To this purpose, the parametrical study is performed and the results are presented. The constitutive equations of non-linear creep of cable under variable stress history offer a strong tool for the real simulation of stochastic variable load history and prediction of realistic time-dependent response (current deflection and stress configuration) of structures with cable elements. By means of suitable stress combination and its gradual repeating various loads and times effects can be modelled.

• Journal of Korean Home Economics Education Association
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• v.9 no.1
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• pp.83-94
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• 1997

The purpose of this study was to provide fundamental information for the determination on secondary Home Economics educations contents on food/nutrition. For this purpose, the Home Economics teachers’needs assessment was performed in view of three(technical, interpretive, emancipatory) systems of action. Questionnaire survey was performed. Among 564 questionnaires sent to Home Economics teachers of 396 secondary school selected by systemic random sampling 362 questionnaires were received and 335 questionnaires were analyzed for this study. As a statistical tool, SPSS/PC(sup)+ was used to analyze frequency, mean, standard deviation, T-test and ANOVA. The major findings in this study were as followings： 1. The most important system of action Home Economics teachers recognized on the contents of food/nutrition was interpretive action, followed by emancipatory action. Technical action was turned out to be the least important system of action. 2. Home Economics teachers recognized that the content of interpretive action was the most achieved action in the text book. The least achieved action was emancipatory action, and the middle was technical action. 3. The needs related to contents of emancipatory action was the highest, followed by interpretive action. The lowest needs was the contents related to technical action. 4. Home Economics teacher’s personal background and situation variables make no difference in the importance, achievement in the text book, and the needs of food/nutrition contents.

• BMB Reports
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• v.29 no.1
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• pp.45-51
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• 1996

Most expressed HLA loci exhibit a remarkable degree of allelic polymorphism, which derives from sequence differences predominantly localized to discrete hypervariable regions of the amino-terminal domain of the molecule. In this study, the HLA-DRB1 genotypes were determined in eighteen control cell lines and 112 unrelated Koreans using the PCR-SSP (Polymerase Chain Reaction-Sequence Specific Primer) technique. 29 specific primer pairs in assigning the DRB1 gene were used. The results of control cells correlated well with the data which was previously reported. The heterozygosity and homozygosity of the DRB1 gene were 0.786 and 0.214, respectively. In a total of 41 different DRB1 alleles and 83 genotypes, the most frequent allele and genotype were DRB1*04 and DRB1*0901/1501, respectively. This study shows that the PCR-SSP technique is relatively simple, fast and a practical tool for the determination of the HLA-DRBI genotypes. Moreover, these results-allele and genotype frequency and heterozygosity of the HLA DRB1 gene-could be useful for database study before being applied to individual identification and transplantation immunity.

• 한국전산유체공학회:학술대회논문집
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• 1995.10a
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• pp.160-168
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• 1995

This paper describes computational efforts on the various energy and environmental problems using Patankar's SIMPLE method. The specific problems included in this study are : pollutant and flammable material dispersions in open and confined areas, aerator-induced flow in a lake for DO(dissolved oxygen) concentration, primary clarifier for water and waste water treatment, hood ventilation in workplace, cyclone and LNG combustors and Dow chlorination reactor. A control-volume based finite-difference method is employed together with the power-law scheme. The pressure-velocity coupling is resolved by the use of the revised version of SIMPLE, says SIMPLER and SIMPLEC. The Reynolds stresses are closed using the standard or the RNG $k-{\varepsilon}$ models. Turbulent reaction is modeled using two fast chemistry methods such as eddy breakup and conserved scalar models. Further, a nonequilibrium model is developed for the application of the chlorination process in the Dow reactor. Other important empirical models and physical insights appeared in this study are presented and discussed in a brief note. The computational method developed in this study is considered, in general, as a viable tool for the design and determination of the optimal condition of various engineering system of interest.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2003.10a
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• pp.201-206
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• 2003

In this paper, it is presented a new technique to the design and real-time implementation of fuzzy control system based-on digital signal processors in order to improve the precision and robustness for system of industrial robot. Fuzzy control has emerged as one of the most active and fruitful areas for research in the applications of fuzzy set theory, especially in the real of industrial processes. In this thesis, a self-organizing fuzzy controller for the industrial robot manipulator with a actuator located at the base is studied. A fuzzy logic composed of linguistic conditional statements is employed by defining the relations of input-output variable of the controller, In the synthesis of a FLC, one of the most difficult problems is the determination of linguistic control rules from the human operators. To overcome this difficult, SOFC is proposed fir a hierarchical control structure consisting of basic level and high level that modify control rules. The proposed SOFC scheme is simple in structure, fast in computation and suitable for implementation of real-time control. Performance of the SOFC is illustrated by simulation and experimental results for robot with eight joints.

• Journal of computational fluids engineering
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• v.2 no.1
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• pp.93-108
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• 1997

This paper describes several computational results on the various energy and environmental problems using Patankar's SIMPLE method. The specific problems included in this study are : pollutant and flammable material dispersions in open and confined areas, buoyancy-driven flow in a lake, primary clarifier for water and waste water treatment, hood ventilation in workplace. cyclone combustor and Dow chlorination reactor. A control-volume based finite-difference method is employed together with the power-law scheme. The pressure-velocity coupling is resolved by the use of the revised version of SIMPLE, says SIMPLER and SIMPLEC. The Reynolds stresses are closed using the standard or RNG κ-ε models. A nonequilibrium turbulent reaction model is developed for the application of the chlorination process in the Dow thermal reactor. Other important empirical models and physical insights appeared in this study are presented and discussed in a brief note. The computational method developed in this study is considered, in general, as a viable tool for the design and determination of the optimal operating condition of various environmental engineering system of interest.