• Title/Summary/Keyword: Detector sensitivity

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The Development of Extravasation Detection Accessory System for the Preventive Contrast Media Extravasation in the Computed Tomography: A Preliminary Report (CT 검사에서 조영제의 혈관외유출 예방을 위한 EDA 시스템 개발의 예비 보고)

  • Kweon Dae-Cheol;Jeong Seok-Hee;Kim Tae-Hyung;Kim Jeong-Goo;Park Peom
    • Progress in Medical Physics
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    • v.17 no.1
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    • pp.32-39
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    • 2006
  • To assess the ability of an extravasation detection accessory (EDA) system to detect clinically important extravascular injection of iodinated contrast material delivered with an automated power injector. Fifty patients referred for contrast material enhanced body computed tomography studied in a prospective, observation study in which the EDA system was used to identify and interrupt any injection associated with clinically Important extravasation. The presence or absence of extravasation was definitively established with multi-detector CT at the injection site (injection rate, $2.0{\sim}2.5$ mL/sec). There were two true positive, extravasation volumes $22{\sim}25$ mL. The EDA system had sensitivity in the detection of clinically important extravasation. The EDA system is easy to use, safe, and accurate In the monitoring of intravenous injections for extravasation, which may prove especially useful in CT applications.

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A Study on the Simultaneous Analysis of Fat-Soluble Vitamins in Food Stuffs and Vitamin Products by High Performance Liquid Chromatography (고성능 액체 크로마토그래피에 의한 식품 및 비타민 제제중의 지용성 비타민의 동시 분석에 관한 연구)

  • Poongzag Kim;Chong-Hyeak Kim
    • Journal of the Korean Chemical Society
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    • v.33 no.1
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    • pp.46-54
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    • 1989
  • The extraction method and quantitative analysis for the fat-soluble vitamins present in food stuffs and vitamin products have been investigated. The simultaneous separation and analysis of the vitamins by reverse phase high performance liquid chromatographic method was conducted using an isocratic elution with methanol : water (95 : 5) eluent on a Novapak $C_{18}$ column. The detection of vitamins was achieved by a variable wavelength UV detector. To improve the detection sensitivity detection wavelengths were set at the highest absorption bands such as 330, 265, 285, and 290nm for the respective vitamins. The analysis for the fat-soluble vitamins was finished within 40 minutes. Alkaline hydrolysis and enzymatic hydrolysis were investigated for the sample preparation; and liquid-liquid extraction and liquid-solid extraction were attempted for the extraction of vitamins. Both hydrolysis methods were turned out to be appropriate for the analysis for vitamins A, D, and E, while for the analysis of vitamin K the enzymatic hydrolysis method demonstrated better results. Diethyl ether, pentane, and n-hexane were found to give higher recovery for the liquid-liquid extraction and silica cartridge for the liquid-solid extraction.

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Development of hybrid shielding system for large-area Compton camera: A Monte Carlo study

  • Kim, Jae Hyeon;Lee, Junyoung;Kim, Young-su;Lee, Hyun Su;Kim, Chan Hyeong
    • Nuclear Engineering and Technology
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    • v.52 no.10
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    • pp.2361-2369
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    • 2020
  • Compton cameras using large scintillators have been developed for high imaging sensitivity. These scintillator-based Compton cameras, however, mainly due to relatively low energy resolution, suffer from undesired background-radiation signals, especially when radioactive materials' activity is very low or their location is far from the Compton camera. To alleviate this problem for a large-size Compton camera, in the present study, a hybrid-type shielding system was designed that combines an active shield with a veto detector and a passive shield that surrounds the active shield. Then, the performance of the hybrid shielding system was predicted, by Monte Carlo radiation transport simulation using Geant4, in terms of minimum detectable activity (MDA), signal-to-noise ratio (SNR), and image resolution. Our simulation results show that, for the most cases, the hybrid shielding system significantly improves the performance of the large-size Compton camera. For the cases investigated in the present study, the use of the shielding system decreased the MDA by about 1.4, 1.6, and 1.3 times, increased the SNR by 1.2-1.9, 1.1-1.7, and 1.3-2.1 times, and improved the image resolution (i.e., reduced the FWHM) by 7-8, 1-6, and 3-5% for 137Cs, 60Co, and 131I point source located at 1-5 m from the imaging system, respectively.

A Modified Quantum Dot-Based Dot Blot Assay for Rapid Detection of Fish Pathogen Vibrio anguillarum

  • Zhang, Yang;Xiao, Jingfan;Wang, Qiyao;Zhang, Yuanxing
    • Journal of Microbiology and Biotechnology
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    • v.26 no.8
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    • pp.1457-1463
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    • 2016
  • Vibrio anguillarum, a devastating pathogen causing vibriosis among marine fish, is prevailing in worldwide fishery industries and accounts for grievous economic losses. Therefore, a rapid on-site detection and diagnostic technique for this pathogen is in urgent need. In this study, two mouse monoclonal antibodies (MAbs) against V. anguillarum, 6B3-C5 and 8G3-B5, were generated by using hybridoma technology and their isotypes were characterized. MAb 6B3-C5 was chosen as the detector antibody and conjugated with quantum dots. Based on MAb 6B3-C5 labeled with quantum dots, a modified dot blot assay was developed for the on-site determination of V. anguillarum. It was found that the method had no cross-reactivity with other than V. anguillarum bacteria. The detection limit (LOD) for V. anguillarum was 1 × 103 CFU/ml in cultured bacterial suspension samples, which was a 100-fold higher sensitivity than the reported colloidal gold immunochromatographic test strip. When V. anguillarum was mixed with turbot tissue homogenates, the LOD was 1 × 103 CFU/ml, suggesting that tissue homogenates did not influence the detection capabilities. Preenrichment with the tissue homogenates for 12 h could raise the LOD up to 1 × 102 CFU/ml, confirming the reliability of the method.

A Study on the Distribution of Atmospheric Concentrations of Sulfur Compounds by GC/FPD (GC/FPD에 의한 대기 중 황화합물 농도분포에 관한 연구)

  • Yang, Sung Bong;Yu, Mee Seon;Hwang, Hee Chan
    • Analytical Science and Technology
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    • v.16 no.3
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    • pp.240-248
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    • 2003
  • Sulfur compounds which are well-known odor-active compounds in industrial area have very low detection threshold values. Trace amounts of volatile sulfur compounds in enviroment air around several odor sources were concentrated in liquid argon bath and determined by gas chromatograph with flame photometric detector (FPD) which exhibits very good selectivity and sensitivity. 25% ${\beta}$,${\beta}$-Oxydipropionitrile on 60/80 Chromosorb W was used as adsorbent for the preconcentration of sulfur compounds in air sample and also as packing material for a packed glass column. Concentration volume of air sample was different from place to place in the range of 0.1~3.0L. Atmospheric concentrations of sulfur compounds in air of residential districts and boundaries of business establishments, and also those in the exhausted gases of emission points such as a sewage disposal plant in industrial area were measured.

Comparison of SPECT Images with $^{99m}Tc$ Collimators ($^{99m}Tc$용 콜리메타의 성능과 SPECT 화상의 영향)

  • Lee, Man-Koo;Lee, Jeong-Ok;Park, Soung-Ock
    • Journal of radiological science and technology
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    • v.24 no.2
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    • pp.35-40
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    • 2001
  • Performance of SPECT imaging systems which use a rotating gamma camera, are affected by characteristics of the detector-collimator assembly, the data acquisition method, and the filter used in imaging reconstruction. The purpose of this study Is to examine image qualifies of SPECT with different types of low energy collimators. The SPECT imaging system in this study is a digital gamma camera system GCA-901A(Toshiba) and a data processing unit Scintipac-700(Shimadzu). The four types of collimators compared are UHR(ultra high resolution), LEHR(low energy high resolution), LEGP(low energy general purpose), and I-123 PAR(Parallel), with 0.27, 0.66, 1.00, and 2.06 relative sensitivity, respectively. In this case of the same collimators, the spatial resolutions measured in the slice plane showed a slight difference in the FWHM values(mean values of UHR, LEHR, LEGP, and I-123 PAR were 11.3 mm, 13.6 mm, 15.8 mm, and 20.4 mm, respectively) between the center and the circumference of the field of view, in the radial direction, but a large difference in the tangential direction, with lower FWHM values(values of UHR, LEHR, LEGP, and I-123 PAR were 8.4 mm, 8.7 mm, 9.3 mm, and 10.8 mm at 12 cm from the center, respectively). In comparison of SPECT images with the four types of collimators, except for the I-123 PAR collimator, image qualities of UHR, LEHR, and LEGP collimators showed only a slight difference. From the point of for, it is expected that the LEGP collimator would be suitable for SPECT imaging with $^{99m}Tc$.

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Development of a Driver Safety Information Service Model Using Point Detectors at Signalized Intersections (지점검지자료 기반 신호교차로 운전자 안전서비스 개발)

  • Jang, Jeong-A;Choe, Gi-Ju;Mun, Yeong-Jun
    • Journal of Korean Society of Transportation
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    • v.27 no.5
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    • pp.113-124
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    • 2009
  • This paper suggests a new approach for providing information for driver safety at signalized intersections. Particularly dangerous situations at signalized intersections such as red-light violations, accelerating through yellow intervals, red-light running, and stopping abruptly due to the dilemma zone problem are considered in this study. This paper presents the development of a dangerous vehicle determination algorithm by collecting real-time vehicle speeds and times from multiple point detectors when the vehicles are traveling during phase-change. For an evaluation of this algorithm, VISSIM is used to perform a real-time multiple detection situation by changing the input data such as various inflow-volume, design speed change, driver perception, and response time. As a result the correct-classification rate is approximately 98.5% and the prediction rate of the algorithm is approximately 88.5%. This paper shows the sensitivity results by changing the input data. This result showed that the new approach can be used to improve safety for signalized intersections.

Development of Tobacco Ripeness Grading Meter Using the Color Sensor (칼라센서를 이용한 담배 완숙도의 식별장치 개발)

  • 이대원;이용국
    • Journal of the Korean Society of Tobacco Science
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    • v.16 no.1
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    • pp.26-33
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    • 1994
  • A tobacco ripeness grading meter was designed and constructed using the color sensor, its performance was evaluated. A degree of ripeness grading of a leaf is very closely related to the measured tobacco leaf color. Measuring the small amount of the reflectance precisely depends on the apparatus including color sensor, light source, detector sensitivity, and geometric characteristics of appratus. To analyze and minimize the variational effects, experiments to select the proper condition were performed. Because of the combined effect mentioned above, the system has some variation on its response. Basis on the results of the experiments, prototype was developed and interfaced to a computer system. The main components of prototype included a tungsten lamp as a light source, Amorphous full color sensor with three filters, regulated D.C. power supply, OP - AMP(741 TC) for amplification, AR - B3001 board for interfacing to a computer with analog to digital conversion, and a compatible IBM PC XT computer. The experimental results of the developed ripeness tobacco leaf measurement system are summarized as following: [1] The output readings of ripeness grade meter for tobacco leaf, which is based on harvesting time, showed the apparent difference in variety of different quality. It was considered suitable that three filters(red, green, blue) in Amorphous full color sensor could be used in four different ripeness degree measurement of tobacco leaf. [2] The output readings of ripeness grade meter for tobacco leaf, which is based on government procurement, showed apparent difference in variety of different quality. Tobacco leaf varieties to stalk position are divided into tips, leaf, cutters, and primings, It is considered suitable that only red filter in the sensor could be used to classify the grade of tobacco leaf within the same kind tobacco stalk. However, the ripeness grade meter was not adequate to classify all the tobacco grades in the four different tobacco leaves.

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Detection Range Improvement of Radiation Sensor for Radiation Contamination Distribution Imaging (방사선 오염분포 영상화를 위한 방사선 센서의 탐지 범위 개선에 관한 연구)

  • Song, Keun-Young;Hwang, Young-Gwan;Lee, Nam-Ho;Na, Jun-Hee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.23 no.12
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    • pp.1535-1541
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    • 2019
  • To carry out safe and rapid decontamination in radiological accident areas, acquisition of various information on radiation sources is needed. In particular, to figure out the location and distribution of radiation sources is essential for rapid follow-up and removal of contaminants as well as minimizing worker damage. The radiation distribution detection device is used to obtain the position and distribution information of the radiation source. In the case of a radiation distribution detection device, a detection sensor unit is generally composed of a single sensor, and the detection range is limited due to the physical characteristics of the single sensor. We applied a calibration detector for controlling the detection sensitivity of a single sensor for radiation detection and improved the limited detection range of radiation dose rate. Also, gamma irradiation test confirmed the improvement of radiation distribution detection range.

Calibration of ShadowCam

  • David Carl Humm;Mallory Janet Kinczyk;Scott Michael Brylow;Robert Vernon Wagner;Emerson Jacob Speyerer;Nicholas Michael Estes;Prasun Mahanti;Aaron Kyle Boyd;Mark Southwick Robinson
    • Journal of Astronomy and Space Sciences
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    • v.40 no.4
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    • pp.173-197
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    • 2023
  • ShadowCam is a high-sensitivity, high-resolution imager provided by NASA for the Danuri (KPLO) lunar mission. ShadowCam calibration shows that it is well suited for its purpose, to image permanently shadowed regions (PSRs) that occur near the lunar poles. It is 205 times as sensitive as the Lunar Reconnaissance Orbiter Camera (LROC) Narrow Angle Camera (NAC). The signal to noise ratio (SNR) is greater than 100 over a large part of the dynamic range, and the top of the dynamic range is high enough to accommodate most brighter PSR pixels. The optical performance is good enough to take full advantage of the 1.7 meter/pixel image scale, and calibrated images have uniform response. We describe some instrument artifacts that are amenable to future corrections, making it possible to improve performance further. Stray light control is very challenging for this mission. In many cases, ShadowCam can image shadowed areas with directly illuminated terrain in or near the field of view (FOV). We include thorough qualitative descriptions of circumstances under which lunar brightness levels far higher than the top of the dynamic range cause detector or stray light artifacts and the size and extent of the artifact signal under those circumstances.