• Title/Summary/Keyword: Design Test Evaluation

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Evaluation of bioequivalence of two enrofloxacin formulations after intramuscular administration in goats

  • Aboubakr, Mohamed Hafez
    • Korean Journal of Veterinary Research
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    • v.53 no.2
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    • pp.77-82
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    • 2013
  • The present study was planned to evaluate the bioequivalence of two commercial formulations of enrofloxacin, which have been marketed as 10% injectable solution after intramuscular administration at a single dose of 2.5 mg/kg body weight to 12 clinically healthy goats The study was carried out on the basis of crossover design. The two formulations were: Baytril as a reference product and Spectrama Vet as a test product. The plasma concentrations of enrofloxacin were measured by high performance liquid chromatography (HPLC) with UV detector. The pharmacokinetics of that data was performed using non-compartmental analysis. The maximum plasma concentration ($C_{max}$), time to reach peak concentration ($T_{max}$), area under concentration-time curve (AUC), elimination half-life ($t_{0.5el}$) were 1.14 and $1.05{\mu}g/mL$, 0.79 and 0.83 h, 5.70 and $5.79{\mu}g.h/mL$, 5.19 and 5.39 h for Baytril and Spectrama Vet, respectively. The 90% confidence interval for the mean ratio of $T_{max}$, $C_{max}$ and AUC were 94.72-116.2, 87.88-97.16 and 86.44-118.72%, respectively. These values falls within the European Medicines Agency bioequivalence acceptance range of 80-125% for both $T_{max}$ and AUC and between 75-133% for $C_{max}$. In conclusion, Spectrama-Vet is bioequivalent to Baytril and both products can be used as interchangeable drug in veterinary medicine practice.

Experimental Study on the Thermal Effect of BIPV Modules Depending on the Ventilation Type of PV Module Backside (후면 환기조건에 따른 건물외피용 태양광발전(BIPV) 모듈의 열적 영향에 관한 실험연구)

  • Yoon, Jong-Ho;Kim, Jae-Ung
    • Journal of the Korean Solar Energy Society
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    • v.26 no.1
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    • pp.81-89
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    • 2006
  • Building integrated photovoltaic (BIPV) system operates as a multi-functional building construction material. They not only produce electricity, but also are building integral components such as facade, roof, window and shading device. On the other hands lots of architectural considerations should be reflected such as Installation position, shading, temperature effect and so on. As PV modules function like building envelope in BIPV, combined thermal and PV performance should be simultaneously evaluated This study is on the combined thermal and PV performance evaluation of BIPV modules. The purpose of this study is to investigate a temperature effect of PV module depending on the ventilation type of PV module backside. Test cell experiment was performed to identify the thermal and power effect of PV modules. Measurement results on the correlation of temperature and power generation were obtained. Those results can be utilized for the development of optimal BIPV installation details in the very early design stage.

The Effects of County-of-Origin, BrandImage, and Corporate Image Dimensions on Brand Evaluations and Purchase Intentions of Smart Phones of Five Brands: A Comparative Study of China and Korea

  • Mo, Li;Zhai, Shuai
    • Journal of Distribution Science
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    • v.11 no.7
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    • pp.47-56
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    • 2013
  • Purpose - In the academic literature, the researches on a comparative study on purchase behaviors of the consumers from emerging and mature markets remain limited. Therefore, this empirical study is attempted to examine the effects of country of origin (COO), brand image and corporate image on the purchase behavior of Chinese consumers (as from emerging market) and Korean consumers (as from mature market). Research Design, data, methodology - In total, 615 valid questionnaires were collected from the main cities of China and Korea respectively, and a multiple group analysis was conducted to test the hypotheses with SPSS 16.0 and AMOS18.0. Results - Chinese consumers are not influenced by country-of-origin effect, whereas Korean consumers are sensitive to it. Both Chinese and Korean consumers are sensitive to brand image, whereas corporate image does appear to influence Chinese consumers but not Korean consumers. The effects of country-of-origin are not more influential in less developed market (China) than more developed market (Korea). Conclusions - According to the results of this empirical study, the country-of-origin effect does impact Korean consumers but not Chinese consumers' purchase behavior. Therefore, multinational companies are relatively free to make the decision, if Chinese consumers are the marketing targets, when choosing manufacturing sites.

Seismic Performance Evaluation of Reinforced Concrete Shear Wall Systems Designed with Special and Semi-Special Seismic Details (특수 및 준특수 상세에 따른 철근콘크리트 전단벽의 내진성능평가)

  • Oh, Hae Cheol;Lee, Kihak;Chun, Young Soo;Kim, Tae Wan
    • Journal of the Earthquake Engineering Society of Korea
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    • v.18 no.4
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    • pp.181-191
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    • 2014
  • This research presents the nonlinear analysis model for reinforced concrete shear wall systems with special boundary elements as proposed by the Korean Building Code (KBC, 2009). In order to verify the analysis model, analytical results were compared with the experimental results obtained from previous studies. Established analytical model was used to perform nonlinear static and dynamic analyses. Analytical results showed that the semi-special shear wall improved significantly the performance in terms of ductility and energy dissipation as expected based on previous test results. Furthermore, nonlinear incremental dynamic analysis was performed using 20 ground motions. Based on computer analytical results, the ordinary shear wall, special shear wall and newly proposed semi-special shear wall systems were evaluated based on the methods in FEMA P965. The results based on the probabilistic approaches accounting for inherent uncertainties showed that the semi-special shear wall systems provide a high capacity/demand (ACMR) ratio owing to their details, which provide enough capacity to sustain large inelastic deformations.

Fit Satisfaction of Formal Jackets in Apparel Product Websites - Focus on Plus-sized Women in Their 20s' and 30' -

  • Ha, Hee-Jung
    • The International Journal of Costume Culture
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    • v.12 no.1
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    • pp.71-84
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    • 2009
  • For fit satisfaction evaluation, the subjects were asked to put on the jackets from the seven manufacturers in random order, view how the jackets fit in a full-body mirror and answer questions regarding fitting in 22 specific areas, including the neck, shoulders, waist, hips and arms, as well as eight questions related to maneuverability. The surveys and evaluations were conducted between October 2007 and November 2008, and the compiled data were analyzed using the SPSS 14.0 statistics program. The One-way analysis of variance was performed to comparatively analyze the differences among the products from the seven manufacturers. Post-hoc tests were performed based on Duncan's test for the criteria that displayed significant differences. The results were summarized as follows. Fit evaluations were performed for the size 88 formal jackets from the seven manufacturers. All items, except the center front line, displayed significant differences at p<0.05 or higher among the manufacturers. The age group 20-39 felt that the main problems were in the shoulder, armscye, upper arm, waist, abdomen and hip areas. Modifying the shoulder area, armscye depth and hip areas severely compromises the jacket's balance, and attention to these areas must be given developed pattern design.

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Evaluation on Shear Behavior of Double-tee Dap-ends with the Least Depth from Optimization Proces (최적이론에 의하여 설계된 최소 깊이 더블티 댑단부 전단거동 평가)

  • 유승룡;김대훈
    • Journal of the Korea Concrete Institute
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    • v.11 no.4
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    • pp.43-54
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    • 1999
  • Shear tests are performed on four full-scale 12.5 m proto-type models, "least depth double tee," which are resulted from the optimization process. Domestic superimposed live load regulation, domestic material properties which is available to product. Korean building code requirements, construction environments and economy are considered as the main factors to establish the process. All of the specimens tested fully comply with the shear strength requirements as specified by ACI 318-95. The research has shown following results. 1) The development length requirement of ACI 318-95 does not seem a good predictor for the estimation of bond failure in a beam with the strands below the supports. 2) The load required for the first initial coner cracking in the dap end and first web shear cracking does not seem to have any relation with the dimension and shear strength of the section in the test beams. 3) The strand slip has a direct relationship with the web shear cracking. However, the coner cracking in the dap end does not give any help for the slip in anchorage. 4) Use of whole area for bearing steel at the bottom of dap end is desired for safe bearing pressure design in the precast prestressed double tee beams. 5) The deflection of beam influences directly on the amount of strand slip at the anchorage after initiation of it, and relationship between them are very linear.

Validity and Reliability of the Korean Version of the Observable Indicators of Nursing Home Care Quality Evaluation Instrument (한국형 노인요양시설 질 관찰평가도구의 타당도와 신뢰도 분석)

  • Lee, Ji-A
    • Journal of Korean Academy of Nursing
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    • v.38 no.3
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    • pp.474-482
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    • 2008
  • Purpose: The purposes of this study were; 1) to test the validity and reliability of the Korean version of Rantz's Observable Indicators of Nursing Home Care Quality Instrument (ONHQ) and 2) to evaluate the quality of Korean nursing homes. Methods: The study employed a three-phase methodological research design. 1) The original instrument of Rantz's. ONHQ was translated into Korean and modified by Korean nursing home experts. 2) A pilot study using the modified instrument was done in 20 nursing homes to examine inter-rater reliability. 3) The validity and reliability were tested.in 98 nursing homes. Results: Seven factors were extracted through factor analysis: 'communication', 'care delivery', 'grooming', 'odor, 'environment-basics', 'environment-access', and 'environment-homelike'. These factors explained 86.07% of the total variance. Cronbach's alpha coefficient of the 30 items was .97 indicating a high internal consistency of the instrument. Inter-rater reliability according to Kappa was .82. The average score of nursing home quality was 112.07 indicating an average range of quality level. Conclusion: The Korean version of the ONHQ was identified as a tool with a high degree of validity and reliability. This tool can be effectively used to assess the quality of nursing homes by professions as well as family members.

A LONG-TERM FIELD TEST OF A LARGE VOLUME IONIZATION CHAMBER BASED AREA RADIATION MONITORING SYSTEM DEVELOPED AT KAERI

  • Kim, Han-Soo;Ha, Jang-Ho;Park, Se-Hwan;Kim, Jung-Bok;Kim, Young-Kyun;Jin, Hyung-Ho
    • Journal of Radiation Protection and Research
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    • v.34 no.2
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    • pp.77-81
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    • 2009
  • An Area Radiation Monitoring System (ARMS) ionization chamber, which had an 11.8 L active volume, was fabricated and performance-tested at KAERI. Low leakage currents, linearities at low and high dose rates were achieved from performance tests. The correlation coefficients between the ionization currents and the dose rates are 1 at high dose rate and 0.99 at low dose rate. In this study, an integration-type ARMS ionization chamber was tested over a year for an evaluation of its long-term stability at a radioisotope (RI) repository of the Young-gwang nuclear power plant. The standard deviation of dose rate of 1 day data and over a 100-days mean value were 6.2 $\mu$R/h and 2.9 $\mu$R/h, respectively. The fabricated ARMS ionization chamber showed stable performance from the results of the long-term tests. Design and performance characteristics of the fabricated ionization chamber for the ARMS from performance-tests are also addressed.

A Study on the Behavior Evaluation & Box Shape Designs of FRP Stiffeners (FRP 보강재의 Box 형상 설계 및 거동 평가에 관한 연구)

  • Jung, Woo-Young;Song, Young-Jin
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.04a
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    • pp.165-168
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    • 2008
  • This paper presents the design, fabrication and performance of a reinforced concrete beam strengthened by GFRP box plate and its possibility for structural rehabilitations. The load capacity, ductility and failure mode of reinforced concrete structures strengthened by FRP box plate were investigated and compared with traditional FRP plate strengthening method. This is intended to assess the feasibility of using FRP box plate for repair and strengthening of damaged RC beams. A series of four-point bending tests were conducted on RC beams with or without strengthening FRP systems the influence of concrete cover thickness on the performance of overall stiffness of the structure. The parameters obtained by the experimental studies were the stiffness, strength, crack width and pattern, failure mode, respectively. The test yielded complete load-deflection curves from which the increase in load capacity and the failure mode was evaluated.

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An Experimental Study on the Minimum Ignition Energy in Low Voltage Spark Discharge by Electrode Material (방전전극 재질과 최소점화에너지에 관한 실험 연구)

  • Choi, Sang-Won
    • Journal of the Korean Society of Safety
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    • v.27 no.3
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    • pp.63-70
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    • 2012
  • In the hazardous areas where explosive gases, vapor or mists exist, electrical apparatus and installations must be the explosion-proof construction to prevent or limit the danger of the ignition of potentially explosive atmosphere. In Korea, nine types of protection have been specified in the government regulations at present: flameproof enclosure, pressurization, oil immersion, increased safety, intrinsic safety, non-incendive, powder filling, encapsulation, and special types. Among these types, the intrinsic safety has the construction which limit or by-pass igniting the electric energy using electronic devices. This type has lots of merits but at the same time requires a high-degree of technology. In this paper, we investigated several dominating factors which affect the minimum ignition energy; this energy plays a very important role in design and evaluation of the intrinsic safety type electrical apparatus. Electrode material, which is one of the most important factors, was intensively studied for the five sorts of material(Al, Cd, Mg, Sn, and Zn) with performing experiment in a low-voltage inductive circuit using IEC-type(International Electro-technical Commission) spark apparatus. The experimental results show that the minimum ignition energy of electrode material is varied: highest in Cd and lowest in Sn. We also confirmed the effect of electrode make-and-break speed.