• Title/Summary/Keyword: Design Template

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In-silico Modeling of Chemokine Receptor CCR2 And CCR5 to Assist the Design of Effective and Selective Antagonists

  • Kothandan, Gugan;Cho, Seung Joo
    • Journal of Integrative Natural Science
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    • v.5 no.1
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    • pp.32-37
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    • 2012
  • Chemokine receptor antagonists have potential applications in field of drug discovery. Although the chemokine receptors are G-protein-coupled receptors, their cognate ligands are small proteins (8 to 12 kDa), and so inhibiting the ligand/receptor interaction has been challenging. The application of structure-based in-silico methods to drug discovery is still considered a major challenge, especially when the x-ray structure of the target protein is unknown. Such is the case with human CCR2 and CCR5, the most important members of the chemokine receptor family and also a potential drug target. Herein, we review the success stories of combined receptor modeling/mutagenesis approach to probe the allosteric nature of chemokine receptor binding by small molecule antagonists for CCR2 and CCR5 using Rhodopsin as template. We also urged the importance of recently available ${\beta}2$-andrenergic receptor as an alternate template to guide mutagenesis. The results demonstrate the usefulness and robustness of in-silico 3D models. These models could also be useful for the design of novel and potent CCR2 and CCR5 antagonists using structure based drug design.

The Design and Implementation of Template Markup Language Script Processor for Electronic Shopping Mall based on XML (XML기반 전자 쇼핑몰을 위한 템플릿 마크업 언어 스크립트 처리기의 설계 및 구현)

  • 김규태;이수연
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.6 no.2
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    • pp.169-174
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    • 2002
  • According to the expansion of the E-Commerce based on Internet, the Interoperability between shopping malls and the expansibility of B2B has been needed. Also, Intelligent User Interface has been needed. The XML based Script Processor, the solution of the problem, is good for Interoperability and if a shopping mall is build by it, it is possible to do customer oriented display that an XML document is displayed with different looks by other style sheet according to customer's preference. In the proposed system, the TMP(Template Markup Language), an auto XML generation script, is defined by XML and the script processor is implemented to work on the shopping mall on the Web.

Development of Domain Model and Reuse Using Model Template (모델 템플리트를 이용한 도메인 모델 개발과 재사용)

  • 김지홍
    • Journal of Internet Computing and Services
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    • v.3 no.3
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    • pp.39-53
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    • 2002
  • Since domain model affects largely on the development of object model and design decisions, this model is widely used in the object-oriented and component-based system development. Current $\infty$ methods and UML notation, however, do not support both engineering with reuse and engineering for reuse, This problem causes delay in project development time and inadequate domain model. The integration of extended UML notation and reuse process method can provide a solution to the reusability problem. In this paper, we designed UML based domain model template for the reuse of domain model and proposed domain model development method for the reuse of analysis information, In addition, it was possible to represent reusable domain model template in UML and to develope domain model in the internet sales domain.

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A Robust Algorithm for Tracking Non-rigid Objects Using Deformed Template and Level-Set Theory (템플릿 변형과 Level-Set이론을 이용한 비강성 객체 추적 알고리즘)

  • 김종렬;나현태;문영식
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.40 no.3
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    • pp.127-136
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    • 2003
  • In this paper, we propose a robust object tracking algorithm based on model and edge, using deformed template and Level-Set theory. The proposed algorithm can track objects in case of background variation, object flexibility and occlusions. First we design a new potential difference energy function(PDEF) composed of two terms including inter-region distance and edge values. This function is utilized to estimate and refine the object shape. The first step is to approximately estimate the shape and location of template object based on the assumption that the object changes its shape according to the affine transform. The second step is a refinement of the object shape to fit into the real object accurately, by using the potential energy map and the modified Level-Set speed function. The experimental results show that the proposed algorithm can track non-rigid objects under various environments, such as largely flexible objects, objects with large variation in the backgrounds, and occluded objects.

A Film-Defect Inspection System Using Image Segmentation and Template Matching Techniques (영상 세그멘테이션 및 템플리트 매칭 기술을 응용한 필름 결함 검출 시스템)

  • Yoon, Young-Geun;Lee, Seok-Lyong;Park, Ho-Hyun;Chung, Chin-Wan;Kim, Sang-Hee
    • Journal of KIISE:Databases
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    • v.34 no.2
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    • pp.99-108
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    • 2007
  • In this paper, we design and implement the Film Defect Inspection System (FDIS) that detects film defects and determines their types which can be used for producing polarized films of TFT-LCD. The proposed system is designed to detect film defects from polarized film images using image segmentation techniques and to determine defect types through the image analysis of detected defects. To determine defect types, we extract features such as shape and texture of defects, and compare those features with corresponding features of referential images stored in a template database. Experimental results using FDIS show that the proposed system detects all defects of test images effectively (Precision 1.0, Recall 1.0) and efficiently (within 0.64 second in average), and achieves the considerably high correctness in determining defect types (Precision 0.96 and Recall 0.95 in average). In addition, our system shows the high robustness for rotated transformation of images, achieving Precision 0.95 and Recall 0.89 in average.

A Design and Implementation of System for Wireless Web Service in Multi-Platform Handhold Devices (멀티 플랫폼 이동단말기의 무선 웹 서비스를 위한 시스템 설계 및 구현)

  • Ryu, Dong-Yeop;Han, Seung-Hyun;Lee, Keun-Soo
    • Journal of the Korea Society of Computer and Information
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    • v.10 no.4 s.36
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    • pp.355-364
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    • 2005
  • An example of such a new device is a mobile phone. The demand for wireless data communication is growing rapidly. However, agencies have not yet completed the standardization of the markup language. Due to the evolution of the Mobile Device, the agencies in this field have provided different data formats with each Mobile Device Platform. Traditionally, contents are hand-tailored to suit the target devices. A key problem is that the characteristics and capabilities of mobile devices are too diverse to service the most suitable mobile contents. Owing to this problem, the need for a reusable document description language increases. In this paper, we defined Template file that is common data to service mobile devices. We proposed method that could be effective wireless web service though design and the implementation of the Call Manager & the XSL Generator. In the methodology, when requesting wireless internet service, the mobile device finds out Markup language and hardware specification of the mobile device through the Call Manager component supports. The XSL Generator component creates XSL file dynamically that is the most suitable to device. Finally, contents is serviced to each device by XSLT.

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Design and Implementation of EDI Document Exchange system based on XML (XML에 기반한 EDI 문서교환 시스템 설계 및 구현)

  • Im, Young-Tae;Han, Woo-Yong;Jung, Hoe-Kyung
    • The Transactions of the Korea Information Processing Society
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    • v.7 no.11S
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    • pp.3603-3612
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    • 2000
  • This paper presents is for the design and implementation of EDI document exchange system based on XML To create a customized document of the users' choice, it designed and created the transaction processor and the template manager, and to make it accessable with the original EDI, a converter function is included, Also, on this system, this protocol stores EDI message structure that needed to exchange as XML format and controls it as DOM API for user can use previous system, And provides interface for user can create template files with converter and transfer necessary elements that can be chosen by user. For this purpose, This system proposes a shows structure information and document converting mechanism solution of EDI documents based on by using XML which does not show proper document conversion mechanism solution in other system so far.

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A Study on the Using of BIM Data and Template for Construction Progress Management (건설공정관리를 위한 BIM데이터와 템플릿 활용 방안)

  • Oh, Kun-Soo;Park, So-Hyun;Song, Jung-Woo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.8
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    • pp.157-163
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    • 2016
  • BIM is currently applied in some domestic construction firms, but it is not being actively utilized due to changes in working environments and qualms about new studies. In order to utilize a BIM model in the design phase, process information is needed during construction, but the input system and utilization method of the process information's state are not complete. Therefore, we propose a BIM template for construction progress management that can show basic BIM information as the construction progresses in an easy and convenient way. This method will facilitate the adoption of BIM and enhance the productivity of construction companies. To this end, we designed a progress explorer for step-by-step progress and work schedules, and we generated three-dimensional views and a progress list by applying unit information (primary units, part units, and detail units) of the work breakdown structure (WBS) to the parameters. To use the BIM template, work progress information is input to the BIM modeling objects through Dynamo. We also used Dynamo for quick and easy calculation of the quantity of materials needed for construction work. To test the BIM template, we applied it to an actual project and evaluated its visibility and a progress list. The results showed that the proposed BIM template facilitates progress management of a project and can thus facilitate the adoption of BIM and improve the productivity of construction companies.

Development of Module for Consumer Content Area Based on the Backward Design (백워드 디자인(Backward Design)에 기초한 소비 단원의 수업 모듈 개발)

  • Lee, Gyeong Suk;Yoo, Taemyung
    • Journal of Korean Home Economics Education Association
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    • v.27 no.2
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    • pp.95-119
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    • 2015
  • This study discussed the major notion of backward design placing emphasis on performance and evaluation, and clarified the concepts of 'understanding' and 'enduring understanding' based on the literature of Wiggins and McTighe and previous studies. This study also developed a sample curriculum module for a consumer unit for 7 class hours based on the 'Understanding by Design' template. This study concluded that backward design can contribute to achieving student's high performance from evaluation planning prior to actual instruction, to utilizing learning with higher order thinking and skills by analyzing key concepts, and to reconstructing curriculum contents considering a teacher's perspective, students' needs, and each school's situation and context.

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Design of an Mail Delivery System based on Mail Template (템플릿기반 메일 전송 시스템 설계)

  • 정옥란;조동섭
    • Proceedings of the Korean Information Science Society Conference
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    • 2002.10e
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    • pp.454-456
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    • 2002
  • 인터넷의 발달로 인하여 웹을 통한 문서 송수신이 많아지면서 이메일의 사용자도 기하급수적으로 늘어나고 있다. 또한 전자상거래에서 무수한 개인적, 직접적 정보 서비스를 이메일로 이용하게 됨에 따라 빠르고 정확한 전송시스템이 현안이 되고 있다. 특히 전자상거래의 상업적 메일은 대량의 메일을 항상 송신해야 하고, 멀티미디어 자료들이 내재되어 있어 메일 용량이 커져서 메일 전송 시 많은 부하가 발생할 수밖에 없는 현실이다. 본 연구는 이러한 문제를 해결하기 위하여 전자상거래의 메일 특수성에 맞춰 템플릿(template)기반 메일 전송방법을 제안하고자 한다. 이는 시간 축을 기준으로 각각의 클라이언트에게 보내는 내용이 같은 항목 하에 일부 내용만이 바뀌는 수평적 유사성(horizontal similarity), 보내지는 폼의 전체적인 디자인 변화나 회사의 정보가 변경되는 수직적 유사성(vertical similarity)특징을 이용한다. 유사성을 가진 메일을 보낼 때 하나의 템플릿으로 작성해서 보내게 되면, 그 이후에는 템플릿 외 사용자 정보만을 전송하게 되며, 메일클라이언트는 컴퓨터에서 이러한 템플릿을 가지고 원래의 메일로 복원을 하게 된다. 이는 전체적인 메일 전송량을 현저하게 줄일 수 있게 해 준다.

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