• 한국산림과학회지
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• 제98권1호
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• pp.26-32
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• 2009

현대 사회에는 도시 생활과 환경으로 인한 건강 문제가 증가하고 있는데 자연환경은 이러한 문제에 좋은 대안으로 대두되고 있다. 특히 숲과 나무는 예전부터 치유를 위한 공간으로 알려져 왔다. 주요우울장애는 매우 일반적이고 만성적인 질병으로 치료방법에는 약물치료와 다양한 심리치료가 포함되어 있다. 그러나 이러한 치료들은 환자들의 기능과 활동을 복귀시키는 것 보다는 기분 증상을 치료하는 것에 집중되어 있다. 본 연구에서는 우울증 환자들의 재활을 위한 산림활동 심리프로그램을 개발하였다. 본 연구에는 약물치료로 우울 증상은 개선되었으나 활동과 기능이 회복되지 못한 9명의 우울증 환자들이 참여하였다. 산림치유 프로그램은 4회기가 진행되었으며 매 회기마다 환자들의 우울증상과 심박변이도를 측정하였다. 4주간의 산림활동 심리프로그램 후 HRSD(Hamilton Rating Scale for Depression)로 측정된 우울감이 유의하게 감소하였으며, 건강관련 삶의 질을 측정하는 SF-36의 하위 척도의 점수가 상승하였고 심박통일성이 증가하였다. 본 예비적 연구 결과, 산림환경을 이용한 활동과 심리치료적 프로그램은 약물치료 중인 우울증 환자들의 기능회복과 재발방지에 긍정적인 역할을 할 가능성을 확인하였다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제11권1호
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• pp.60-69
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• 2000

목 적：본 연구는 소아, 청소년의 강박 증상을 평가하기 위한 도구인 아동용 예일-브라운 강박척도 (Children's Yale-Brown Obsessive Compulsive Scale：Y-BOCS)의 한국판을 제작하여 그 신뢰도와 타당도를 검증하고자 시행되었다. 방 법：강박장애로 진단된 42명의 아동과 청소년들을 대상으로 CY-BOCS를 시행하였다. 평가자간 신뢰도를 측정하기 위하여 20명의 환자를 2명의 평가자가 동시에 면담하였다. 수렴타당도와 변별타당도의 검증을 위해 총괄적인 임상 인상척도-강박장애(Clinical Global Impression-Obsessive Compulsive Disorder：CGI-OCD), 아동용 Leyton 강박 척도(Leyton Obsessional Inventory-Child Version：LOI-CV), 소아우울척도(Child Depression Inventory：CDI), 소아 상태-특성 불안척도(State-Trait Anxiety Inventory for Children：STAI-C)를 시행하였다. 결 과：Cronbach's ${\alpha}$값으로 평가한 내적 일치도는 0.86으로 높게 나타났다. CY-BOCS 전체 점수, 강박사고, 강박행동 소척도 점수에 대한 군내 내적일치도는 각각 0.94, 0.94, 0.84로 우수한 평가자간 일치도를 보였다. CY-BOCS 전체 점수와 CGI-OCD 점수간의 상관관계는 매우 높게 나타났고(r=0.88), LOICV 총점과도 통계적으로 유의한 상관관계(r=0.51)가 관찰되었다. CY-BOCS 전체 점수와 STAI-C의 상태불안 점수간에는 상관관계가 나타나지 않았고(r=0.25), 특성불안 점수(r=0.43) 및 CDI 점수(r=0.49) 와는 유의한 상관관계를 나타냈다. 결 론：본 연구결과, 한국판 CY-BOCS의 높은 타당도 및 신뢰도가 입증되었으며, 향후 강박 증상의 객관적인 평가 및 정량화를 위해 유용하게 사용될 수 있을 것이다.

• 농촌의학ㆍ지역보건
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• 제22권1호
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• pp.49-59
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• 1997

Backgrounds : There has been many studies investigating the causes of farmers' syndrome. In some studies, psychologic stress is related to farmer's syndrome. And the diagnostic criteria of farmer's syndrome is similar to those of generalized anxiety disorder. So we carried out this study to investigate the psychiatric causes of farmers' syndrome. Methods : This study was done in some rural and urban areas of Kyoungsangnam Province, July, August, October and November of 1996. Those who came to free medical service and completed interview, medical examination and laboratory examination and 20-59 years old were 150 persons. And those who came to health center for health examination and completed only interview and 20-59 years old were 94 persons. The questionnaire was composed of sociodemographic factors, health risk factors, farmer's syndrome, work load, BEPSI(inventory to measure stress), Spielberger's state-trait anxiety inventory, self-rating depression scale. To examine statistical significance, we used X2-test, Mantel-Haenszel test for linear association, t-test, ANCOVA, correlation, multiple regression, logistic regression. Results : The prevalence of farmer's syndrome, adjusted for age and sex with population of Kyungsangnam Province of 1993 was 208 per 1,000(90 per 1,000 in men and 329 per 1,000 in women). In bivariate analysis, farmer's syndrome was significantly related to age, sex, job, income, smoking, alcohol drinking, work load, BEPSI, state anxiety, trait anxiety, depression, body mass index, Hwa-Byung, hypertension, anemia. However, when age and sex were adjusted, job was not significantly related to farmer's syndrome. The score of farmer's syndrome was significantly related to age, sex, work load, BEPSI, trait anxiety by multiple regression. Farmer's syndrome was significantly related to increasing age(odd ratio 1.079, 95% C.I. 1.060 - 1.099), sex(odds ratio of male 0.434, 95% C.I. 0.349 - 0.540), and BEPSI(odds ratio 1.231, 95% C.I. 1.148 - 1.320) by logistic regression. Results of logistic regression analysis of the component symptoms of farmer's syndrome were as follows. Shoulder stiffness was significantly related to increasing age, female sex and BEPSI. Lumbago was significantly related to increasing age, female sex and trait anxiety. Numb limbs and nocturia was significantly related to increasing age and female sex. Breathlessness was significantly related to work load, sleeplessness was significantly related to depression, dizziness was significantly related to job and state anxiety, and abdominal fullness was significantly related to female sex. Conclusion : Farmers' syndrome was related to work load, but was more related to psychiatric factors such as BEPSI and trait anxiety. And the occupation was not risk factor of farmers' syndrome in this study, so further study is needed to investigate the cause of farmers' syndrome.

• Korean Journal of Acupuncture
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• 제27권4호
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• pp.97-109
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• 2010

Objective : To examine whether any correlation between tendency towards depression and tenderness at special acupuncture points exists, thus to explore the potential diagnostic property of acupuncture points. Methods : A total 31 subjects were included in this study. They filled out questionnaires about their mental [Beck Depression Inventory (BDI), Stress Response Inventory (SRI), Profile of Mood States (POMS)] and physical (fatigue due to overexertion, and food accumulation) symptoms. Identical weight around Alarm points (CV17, CV12, ST25, CV5, CV4, and LR13) and transport points (BL14, BL20, BL21, BL22, BL25, and BL27) was given using an algometer and the subjects rated their pain on an 11-point numerical rating scale. Heart rate variability (HRV) was also measured. Results : The subjects were divided into two groups, normal and depressive tendency groups with a cut-off point of nine on BDI. The depressive tendency group reported significantly higher values in SRI, POMS, and questionnaire for fatigue due to overexertion. In the pressure pain measurement, depressive tendency group had more pressure pain at CV12, left side of BL20, BL14, BL22 and both sides of BL21, BL25, BL27, significantly (each p<0.05). The data of HRV did not show significant differences between groups. Conclusions : People with a tendency towards depression may be prone to stress, negative mood, and fatigue due to overexertion. In addition, they may be more likely to develop tenderness at alarm points and transport points compared with healthy people. Further research is needed to confirm this finding.

• 한국산학기술학회논문지
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• 제19권1호
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• pp.355-367
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• 2018

본 연구는 C시에 소재한 보건소의 방문건강관리 대상 노인 중 만성 관절통증이 있는 65세이상 취약계층 재가 여성노인 234명을 대상으로 삶의 질에 영향을 미치는 주요 요인을 파악하기 위한 서술적 상관관계 연구이다. 본 연구의 자료는 일반적 특성, 통증양상, 통증정도, 지각된 건강상태, 일상생활능력, 수면양상, 우울, 삶의 질로 구성된 구조화된 설문지를 통해 2017년 2월 16일부터 3월 13일에 걸쳐 수집되었으며, t-test, ANOVA, 상관분석, 위계적 다중 회귀분석으로 분석하였다. 연구결과, 대상자의 일반적 특성을 포함하여 대상자의 삶의 질에 영향을 미친 변수는 우울(${\beta}=-.60$, p<.001), 통증정도(${\beta}=-.15$, p=.007), 의료보장 유형(${\beta}=.15$, p=.001), 지각된 건강상태(${\beta}=.14$, p=.007), 통증지속기간(${\beta}=-.10$, p=.019), 결혼상태(${\beta}=.10$, p=.024), 일상생활능력(${\beta}=.09$, p=.036)순으로 나타났으며, 모형의 총 설명력은 63.1%였다. 본 연구를 통해 만성 관절통증이 있는 재가 여성노인의 삶의 질을 향상시키기 위해서는 지역사회 중심의 체계적인 우울 예방 및 관리 프로그램 운영이 우선 실시되어야 하며, 특히 경제적으로 취약한 공적부조 대상 노인의 삶의 질에 관심을 기울여야 하고, 통증 발현 초기부터 통증에 대한 정확한 사정을 토대로 통증완화중재 개입을 시행해야 한다.

• 동의신경정신과학회지
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• 제28권3호
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• pp.217-230
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• 2017

Objectives: This study was conducted to review studies on somatization disorder in traditional Chinese medicine. Methods: We reviewed studies in the China National Knowledge Infrastructure (CNKI) to 2017. Keywords were 軀體化障碍, Somatization disorder, somatic symptom disorder. We included Randomized Controlled Trial (RCT), and excluded non-Randomized Controlled Trial (nRCT), non-related somatization disorder or traditional Chinese medicine, non-clinical trials, dissertations for degrees. Jadad scale and Cochrane Library's Risk of Bias (RoB) were used for assessment of the quality of studies. Results: Twelve studies were selected. The Chinese Classification of Mental Disorders-3 (CCMD-3) was most frequently used as diagnostic criteria for somatization disorder. As for outcome measurement, Hamilton Rating Scale for Depression (HAMD) was used most commonly. Meta-analysis of 10 studies revealed effective rate of Chinese Herbal Medicine groups (CHM) was significantly higher than Western Medicine groups (WM) (RR: 1.14, 95% CI: 1.02 to 1.27, p=0.02, $I^2=40%$). There was no significant difference in effective rate of CHM+WM and WM (RR: 1.12, 95% CI: 0.84 to 1.49, p=0.46, $I^2=83%$). And also, effective rate of Acupuncture group (Acu) revealed no significant difference compared to that of WM (RR: 1.17, 95% CI: 0.95 to 1.44, p=0.13, $I^2=84%$). For HAMD, there was significant difference in CHM vs, WM group and Acu vs. WM group. Quality of selected 12 RCTs was low. Conclusions: Therapies practiced in traditional Chinese medicine may be effective options for somatization disorder. treatment. For further clinical studies in Korean medicine, this study could be groundwork for development of diagnosis and treatment on somatization disorder.

• 동의신경정신과학회지
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• 제5권1호
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• pp.41-60
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• 1994

The objective of this paper is to verify clinical effects of Lyu's Soyosan(柳氏逍遙散) and Lyu's Kwipithang(柳氏歸脾湯). They were prescribed to the enperimental student group suffering from mental stress and annoyed by psychological instability. From the biochemical examination before and after medication, we measure the amount of hormonal variation in thyroid hormone(TSH, $T_4$) and adrenocortical hormone(ACTH, cortisol) The results are as follows. 1. The average of self-rating anxiety scale(SAS) in test group is $41.00\;{\pm}\;7.84$. This value is statistical significant and higher than one of normal person(age 20-39). The average of a global assesment of recent stress(GARS) scale is $28.62\;{\pm}9.00$. There is statistical correlation coefficient between SAS and GARS (p < 0.001). 2. Both Lyu's Soyosan(柳氏逍遙散) and Lyu.s Kwipithang (柳氏歸脾湯) groups show statistically significant reduction of total cholesterol and triglyceride level in serum lipid after ten day medication. 3. It is observed that Lyu's Soyisan(柳氏逍遙散) and Luy's Kwipithang (柳氏歸脾湯) groups have increasing tendency of TSH. The statistically significant reduction of $T_4$ was found in two groups after ten day medicaton. 4. It is observed that Lyu's Soyosan(柳氏逍遙散) and Lyu's kwipithang (柳氏歸脾湯) group have statistically significant reduction of serum cortisol level after ten day medication, Both groups have statistically significant reduction of plasma ACTH level after twenty day medication. From these results, it is verified that both Lyu's Soyosan(柳氏逍遙散) and Lyu's Kwipithang (柳氏歸脾湯) have anti-stress effects against psychological instability and mental stress. The Lyu's Soyosn(柳氏逍遙散) shows special effectiveness in depression of liver-energy(肝氣鬱結) and the Lyu's Kwipitang (柳氏歸脾湯) is also effective in deficiency heart-blood(心血不足).

• 정신신체의학
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• 제4권1호
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• pp.13-20
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• 1996

This study was performed to explore the frequency of panic attack induced by sodium lactate in alcohol dependence patients and to compare the extent of blunted growth hormone reponses after clonidine infusion with that of normal controls. The authors investigated 10 alcohol dependence patients receiving inpatient care in Hangang Sacred Heart Hospital from March 2, 1993 to August 31, 1993 and 10 normal controls. The disagnosis of alcohol dependence was based on DSM-III-R. Thirty minutes after the sodium lactate infusions clonidins were administrated. Venous bloods were sampled before the sodium lactate infusions, and 30, 45, 60, 90 minutes after the administrations of clonidine. Plasma growth hormone levels were measured by RIA method. The results were as follows : 1) In the questionaires of Hamilton Anxiety Rating Scale, Hamilton Depression Raing Scale, CAGE, Korean MAST, the scores of alcohol dependent patients were higher than those of normal controls. 2) Sixty percent of alcohol dependence patients and twenty percent of normal controls had panic attacks induced by sodium lactate. 3) All panic attacks induced by sodium lactate were relieved after clonidine infusions. 4) There were blunted growth hormone responses after clonidine infusions in alcohol dependence patients who had sodium lactate induced panic attacks like panic disorder patients. These results suggest that alcohol dependence patients may have noradrenergic abnormality same as panic disorder patients and two disorder may have high biological correlations each other.

• 생물정신의학
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• 제22권4호
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• pp.163-172
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• 2015

Objectives This study was aimed to examine the multidimensional relationship between auditory verbal hallucinations (AVHs) and Positive and Negative Syndrome Scale (PANSS) factors of psychopathology in the patients with schizophrenia. And we explored the differences between assessments to hallucination by the clinicians and patients. Methods 82 patients with schizophrenia who were assessed by the Hamilton Program for Schizophrenia Voices Questionnaire (HPSVQ), Psychotic Symptom Rating Scale-Auditory Hallucination (PSYRATS-AHS), and the PANSS were recruited. Hwang's five-factor model of PANSS, items and total scores of hallucination scales, Kim's and Haddock's factor models of hallucination were applied to examine the correlations between psychopathology and AVHs. AVH-positive patients was 50 in PANSS-HPSVQ group and 24 in PANSS-PSYRATS-AHS. These two groups were separately analyzed. Results Among the five factors of the PANSS, negative and depression/anxiety factors were correlated with the total scores of HPSVQ and PSYRATS-AHS, and positive and autistic preoccupation factors were correlated only with the total score of PSYRATS-AHS. The activation factor was correlated with none of the total scores of HPSVQ/PSYRATS-AHS. These correlation patterns of a total score of HPSVQ/PSYRATS-AHS were same in the emotional factor of HPSVQ and physical factor of PSYRATS-AHS respectively. In the items which showed significant correlations, correlation coefficients of PANSS-PSYRATS-AHS group ranged between 0.406-0.755 and those of PANSS-HPSVQ ranged between 0.283-0.420. Conclusions This study suggested that the psychopathological domains of schizophrenia were differentially correlated with AVHs and the assessment of AVHs by clinicians and patients showed substantial differences which should be integrated into the therapeutic interventions.

• 대한불안의학회지
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• 제16권1호
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• pp.41-48
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• 2020

Objective : There have been limited scientific studies differentiating those who attempt suicide from those who think about suicide but do not attempt suicide. Altered event-related potential (ERP) performance, such as GoNogo ERP has been regarded as the neurocognitive processes associated with behavioral inhibition and poor impulse control. The purpose of this study was to investigate the association between Nogo ERP and suicide attempt. Methods : A total of 63 participants (33 participants with suicide ideation and 30 with suicide attempt) were recruited, and performed GoNogo tasks during the electroencephalogram measurement. Depression, anxiety, emotional regulation and impulsivity were evaluated by self-rating scales. The clinical measures and Nogo P3 component were compared between the groups. The correlational analyse was conducted to evaluate the relationship between the clinical characteristics and the Nogo P3 component. Results : Participants with suicide attempt significantly decreased the Nogo P3 amplitudes at the frontal-central electrode than participants with suicide ideation (p=0.004, FDR adjusted p=0.032). In the correlation analysis, the Nogo P3 amplitude at frontal-central electrode was correlated with the total score of the Barrett impulsivity scale (r=-0.383, p=0.002), attentional impulsivity (r=-0.365, p=0.003) and motor impulsivity (r=-0.389, p=0.002) subscales of the Barrett impulsivity scale. Conclusion : These findings suggest that the decreased Nogo P3 amplitude may be one of the candidates of biological marker for poor impulse control in those who attempt suicide.